Formulating With Whey In A Fully Transparent Market. Chris Lockwood, PhD President May 22-23, 2018

Transcription

1 Formulating With Whey In A Fully Transparent Market Chris Lockwood, PhD President May 22-23, 2018

2 Driving Protein Demand Only Major Nutrient That Stimulates Muscle Building (Muscle Protein Synthesis, or MPS) Increased Calorie-Burning (Thermogenic) vs CHO or FAT Reduces Hunger More than CHO or FAT Increases Body Fat and Weight Loss, and Reduces Negative Effects on Lean Body Mass when Combined w/ a Calorie-Restricted Diet Reduces Age- or Inactivity-induced Muscle and Strength Loss Improves Insulin Sensitivity and Blood Glucose Control Supports Healthy Blood Pressure and Inflammatory Response Critical for a Robust Immune System Westerterp-Plantenga MS et al. 2012; Leidy HJ 2014; Clifton PM et al. 2014; Petzke KJ et al. 2014; Margolis LM and Pasiakos SM. 2013; Guadagni M and Biolo G. 2009; Teunissen-Beekman KF and van Baak MA. 2013; McLean RR et al

3 Why Whey? WHEY EGG CASEIN MEAT SOY PROTEIN ALGAE PEA HEMP RICE OTHER PLANT

4 Whey Most Effective Protein Source for Stimulating MPS Fast(est) Protein Increases Essential (EAA), Branched-Chain Amino Acid (BCAA), and Bioactive Peptide Rate of Appearance in Blood Powerful Antioxidant Support Increases Glutathione Reduces Inflammation and Cortisol Response / Improves Recovery from Physiological Stress Increases Non-Glucose Insulin Release Improves Exercise Recovery Anabolism, Increases Blood Flow, Reduces Muscle Breakdown, Improves Glucose Metabolism and More Morifuji M et al. 2010; Ha E and Zemel MB. 2003; Katsanos CS et al. 2008; Beelen M et al. 2008; Dangin M et al. 2002; Krissansen GW. 2007; Calbet JA and Holst JJ. 2004; Lockwood CM et al. 2017; Hulmi JJ et al. 2010; Devries MC and Phillips SM. 2015; Miller PE et al. 2014; Moore DR et al

5 Survive -v- Thrive Milk Protein Isolate ( SMP ) Preferentially Increases Protein Synthesis Efficiency in Skeletal Muscle ( P area ) Soy Protein Isolate ( SSP ) Preferential to Non-Skeletal Muscle ( S bed ) & Increases Nitrogen Excretion / Loss Fouillet H et al. J Nutr 2002;132:

6 Fast Effects via Fast Protein? At Rest: Whey +93% > Casein Whey +18% > Soy After Exercise: Whey +122% > Casein Whey +31% > Soy Tang JE et al. J Appl Physiol 2009;107:

7 Just the EAAs or Leucine? Mobley et al. J Dairy Sci 2017;100(1):48-64

8 Protein Type I Adaptation Potential Training Type II Adaptation Potential Whey Skeletal Muscle Adaptation Potential Whey 2x MORE Effective Than Increasing Skeletal Muscle Resistance Training Adaptation Mobley et al. Nutrients 2017;9:972

9 Testosterone, Not Leucine? RODENTS HUMANS Mumford et al. [In Review] 54 mg Leu Post-Ex 50 mg Leu Post-Ex WPC = +33.3% Increase in Circulating Testosterone Mobley et al. [in Review]

10 Anabolic : Catabolic Whey Post-Exercise Testosterone Whey Post-Exercise Cortisol Kraemer WJ et al. J Am Coll Nutr 2013;32(1):66-74

11 Does Protein Form Matter? Any Whey Muscle Mass Extensive WPH Fat Loss Lockwood CM et al. J Amer Coll Nutr 2017;36(1):16-27

12 Moderate WPH (~12 DH) vs WPC FAT & CHO Metabolism PRO min Post-Prandial Roberts MD et al. Appl Physiol Nutr Metab 2014;39:

13 Form & Source Specificity Hydrolysates Acute Anabolism Protein Source Affects Metabolism Morifuji M et al. J Agric Food Chem 2010;58:

14 But Plant Protein Pandemonium Whey IS Vegetarian Whey IS Sustainable / Renewable Whey CAN BE Certified Non-GMO Whey CAN BE Certified Organic Whey IS Gluten Free Whey IS Easy to Flavor* Whey IS Easy to Digest Whey IS Low Allergen* Whey IS A Complete, High Quality Protein And, Whey IS The Human Body s First Protein

15 No Other Protein Is More Natural LACTATION PERIOD WHEY (%) CASEIN (%) Early Mature Late No Vegan Moms Do NOT Produce Vegan Milk Liao Y et al. J Proteome Res 2017;16(11): ; Kunz C and Lonnerdal B. Acta Paediatr 1992;81(2):107-12

16 Win, The Full Transparency Whey Invest In Experimental & Finished Product Research Publish Analytical Testing Nutritionals Amino Acid Profiles M.W. Profiles Contaminants (e.g., Pesticide Residues, HMs) Full Disclosure Labeling of Protein Blends Social Warrior Marketing 3 rd Party Validation Certs & Seals Animal Husbandry / Happy Cows Story Telling

17 Cut A New Path, But Don t Plant Landmines

18 Which Whey?

19 Formula Recommendations Size Strength Performance WPC WPI Low DH WPH (< 10%) (from WPC) (from WPC) (from WPC) Mod DH WPH (10%-25%) High DH WPH (> 25%) Weight Body Fat Aging Effects Clinical Health Keto Diet / (from WPI) (from WPI) Carb Restricted Lactose Avoidance (from WPI) (from WPI) (from WPI) (from WPI) Low Allergenicity Affordable Pricepoint Fashion Over Function (i.e., Taste & Speed to Market Priority)

20 Thank You Chris Lockwood, PhD, CSCS (phone)