Complying with 1907/2006/EEC Regulation of 16 December 2006 ("REACH Regulation") and REGULATION(EC) No 1272/2006(CLP)

Transcription

1 Substance Name: PHTHALC ANHYDRDE Page of 4 Complyng wth 907/2006/EEC Regulaton of 6 December 2006 ("REACH Regulaton") and REGULATON(EC) No 272/2006(CLP) Secton. DENTFCATON OF THE SUBSTANCE/PREPARATON AND OF THE COMPANY/ UNDERTAKNG. Product dentfer Substance Name: PHTHALC ANHYDRDE Trade name: PHTHALC ANHYDRDE Synonyms: 2-Benzofuran-,3,-done, Phthalc acd anhydrde,,2-benzene-dcarboxylc acd anhydrde, Phthalandone. Chemcal formula: C8H403 Product type: Anhydrde of organc aromatc d!carboxylc " acd. CAS number: EC number: S REACH regstratonno(s): Relevant dentfeduses of the substance or mxture and uses advsed aaanst ntended Uses: Phthalc anhydrde s used as an ntermedate and as a monomer for polymer formaton. dentfed Uses: Producton of Substance Use as anntermedate Use as a Monomer for Polymer Formaton. Use n Formulaton, Mxture, Refllng and Loadng. Use as a Laboratory Chemcal. Uses advsed aganst: Ths product s not recommended for any ndustral, professonal or consumer use other thanthe dentfeduses above. There s no consumer use of Phthalc anhydrde..3 Detals of the suppler of the safetv data sheet Company/undertakngdentfcaton Suppler/Manufacturer: Everchem Specalty Chemcals 400 N. Provdence Road Meda, PA 9063, USA Tel: (484) Fax: (484) E-mal address of person responsble for ths SOS: gamram@orl.co.l.4 Emergency telephone number For Chemcal Emergency - Spll, Leak, Fre, Exposure or Accdent Call CHEMTREC Day or Nght USA + Canada = /

2 Substance Name: PHTHALC ANHYDRDE Page 2 of 4 Secton 2. HAZARDSDENTFCATON 2. Classfcaton of the substance or mxture Accordng to EC Drectve 200/59/EC Most mportant Hazards: "_" / Classfcaton n accordance to Regulaton (EC)No. 272/2008 (CLP/GHS) Physcal / Chemcal Hazards: Not Classfed Health Hazards: Acute toxcty - Oral, Category 4 Eye damage, Category Respratory senstzaton, Category Skn senstzaton, Category Skn rrtaton, Category 2 Specfc target organ toxcty - nhalaton, Category 3 Envronmental Hazards: Not Classfed Classfcaton accordng to Drectve 67/548/EEC (DSD) or 999/45/EC Xn-Harmful R22: harmfulf swallowed R3738: rrtatng to respratory system and skn R4: rsk of serous damage to eyes R42/43: may cause senstzaton by nhalaton and skn contact! f 2.2 Label elements Labelng n accordance wthregulaton272/2098 (CLP) Hazard pctograms: Sgnal word: Danger

3 Substance Name: PHTHALC ANHYDRDE Page 3 of 4 Hazard statements: H302: Harmfulf swallowed. H335: May cause respratory rrtaton. H35: Causes skn rrtaton. H38: Causes serous eye damage. H334: May cause allergy or asthma symptoms or breathng dffcultes f nhaled. H37: May cause an allergc skn reacton. Precautonary Statements: P232: Protect product from mosture P26: Avod breathng dust. P264: Washhands thoroughly after handlng. P280: Wear protectve gloves/protectve clothng/eye protecton/face protecton. P30+P32: F SWALLOWED: call a POSON CENTER or doctor / physcan f you feel unwell. P302+P352: F ON SKN: Wash wth plenty of soap and water. P305+P35+P338: F N EYES: Rnse cautously wth water for several mnutes. Remove contact lenses, f present and easy to do. Contnue rnsng. P337+P33: F eyes rrtaton occurs: Get medcal advce/attenton. P402+P233: Store n a well-ventlated place. Keep contaner tghtly closed. 2.3 Other hazards N/A Secton 3. COMPOSTON/NFORMATON ON NGREDENTS Substance/preparaton Formula: C8H4O3 Molecular wegth: 48.2 g/mol ngredent name PHTHALC ANHYDRDE REACHregstratonno CAS number EC number o/o EU Classfcaton z 99.8% Xn; R22 X; R4 X; R37/38 R42/43 GHS Classfcaton Acute Tox. 4 H302 Eye damage H38 Skn rrt. 2 H35 STOT SE 3 H335 Resp. Sens. H334 Skn Sens. H37 There are no addtonal ngredents present whch, wthn the current knowledge of the suppler and n the concentratons applcable, are classfed as hazardous to health or the envronment and hence requre reportng n ths secton. Occupatonal exposure lmts, f avalable, are fsted n secton & See secton 6 for the full text of theh-statements and R-phrases declared above.

4 \, SAFETY DATA SHEET Substance Name: PHTHALC ANHYDRDE Page4 of 4 Secton 4. FRST AD MEASURES 4. Product-specfc hazards Causes eye damage. Causes sknrrtaton / senstzaton. May cause respratory senstzaton. 4.2 General advce Take care to self-protect by avodng becomng contamnated. Seek medcal assstance - show the safety data sheet or label f possble. 4.3 Descrpton of frst ad measures nhalaton: Move exposed person to fresh ar. f t s suspected that fumes are stll present, the rescuer should wear an approprate mask or self-contaned breathng apparatus. Keep person warm and at rest. f not breathng, f breathng s rregular or f respratory arrest occurs, provde artfcal respraton or oxygen by traned personnel. t may be dangerous to the person provdng ad to gve mouth-to-mouth resusctaton. Get medcal attenton. f unconscous, place n recovery poston and get medcal attenton mmedately. Mantan an open arway. Loosen tght clothng such as a collar, te, belt or wastband. n the event of any complants or symptoms, avod further exposure. } f { } } 2 "j ngeston: Wash out mouth wth water. Move exposed person to fresh ar. Keep person warm and at rest. f materal has been swallowed and the exposed person s conscous, gve small quanttes of water to drnk. Stop f the exposed person feels sck as vomtng may be dangerous. Do not nduce vomtng unless drected to do so by medcal personnel. f vomtng occurs, the head should be kept low so that vomt does not enter the lungs. Get medcal attenton. Never gve anythng by mouth to an unconscous person. f unconscous, place n recovery poston and get medcal attenton mmedately. Mantan an open arway. Loosen tght clothng such as a collar, te, belt or wastband. \ Skn contact: Sold Materal: Flush contamnated skn wth plenty of water. Remove contamnated clothng and shoes. Contnue to rnse for at least 0 mnutes. Get medcal attenton. n the event of any complants or symptoms, avod further exposure. Wash clothng before reuse. Clean shoes thoroughly before reuse. Materal n Lqud State: Wash skn mmedately wth plenty of water and soap. Call a physcan. CONTACT WTH THE HOT MELT: Coolng mmedately wth plenty of water. Do not remove product crusts whch may have formed nether forcbly nor by applyng any solvents to the skn nvolved. n order to obtan medcal care for possble bums and for a smooth cleansng of the skn, seek medcal advce mmedately. Eye contact: Sold Materal: Get medcal attenton mmedately. mmedately Rush eyes wth plenty of water, occasonally lnng the upper and lower eyelds. Check for and remove any contact lenses. Contnue to rnse for at least 0 mnutes. Chemcal bums must be treated promptly by a physcan. Materal n Lqud State: mmedately Rush eyes wth runnng water for at least 5 mnutes, keepng eyelds open. Seek mmedate medcal attenton. 4.4 Advce to physcan Causes eye damage. Causes sknrrtaton / senstzaton. Materal may cause respratory senstzaton. No specfc antdote; medcal staff contacts Posons nformaton Center. All treatments should be based on observed sgns and symptoms of dstress n the patent. Consderaton should be gven to the possblty that overexposure to materals other than ths product may have occurred.

5 J 5 f SAFETY DATA SHEET Substance Name: PHTHALC ANHYDRDE Page 5 of 4 Secton 5: FRE-FGHTNG MEASURES 5. Extnaushna meda Sutable extnqushna meda: Use an extngushng agent sutable for the surroundng fre. Examples: water spray, water fog or foam. For small fre use dry powder or carbon doxde (002) extngusher, dry sand or fre fghtng foam. J Unsutable extnqushnq meda: None are known. 5.2 Hazardous combuston products Decomposton products may nclude the followng materals: carbon oxdes (carbon monoxde and carbon doxde), smoke and soot. 5.3 Specal exposure hazards durna fre fqhtnq No specfc fre or exploson hazard. Promptly solate the scene by removng all persons from the vcnty of the ncdent f there s a fre. No acton shall be taken nvolvng any personal rsk or wthout sutable tranng. J! 2 j 5 : ~ 5.4 Specal protectve measures for frefahters Fre-fghters should wear approprate protectve equpment and self contaned breathng apparatus (SCBA) wth a full face-pece operated n postve pressure mode. Other: All combuston resdues and contamnated water from fre-fghtng should be dsposed of accordng tolocal regulatons Secton 6: ACCDENTAL RELEASE MEASURES 6. Preventon of secondary rsk None. 6.2 Personal precautons No acton shall be taken nvolvng any personal rsk or wthout sutable tranng. Keep unnecessary and unprotected personnel from enterng. Do not touch or walk through splt materal. Provde adequate ventlaton. Put on approprate personal protectve equpment (see secton 8). 6.3 Envronmental precautons Avod dspersal of splled materal and runoff and contact wth sol, waterways, drans and sewers. nform the relevant authortes f the product has caused envronmental polluton (sewers, waterways, sol or ar). Large spll: Move contaners from spll area. Prevent entry nto sewers, water courses, basements or confned areas. Vacuum or sweep up materal and place n a desgnated, labeled waste contaner. Dspose of va a lcensed waste dsposal contractor. Small spll: Move contaners from spll area. Vacuum or sweep up materal and place n a desgnated, labeled waste contaner. Dspose of va a lcensedwaste dsposal contractor.

6 Substance Name: PHTHALC AMHYDRDE Page 6 of Reference to other sectons See Secton for emergency contact nformaton. See Secton8 for nformaton on approprate personal protectve equpment. See Secton 3 for addtonal waste treatment nformaton. Secton 7: HANDLNG AND STORAGE 7. Advce on safe headlne Preventon of user exposure: Put on approprate personal protectve equpment. Eatng, drnkng and smokng should be prohbted n areas where ths materal s handled, stored and processed. Persons wth a hstory of skn senstzaton problems or asthma, allerges or chronc or recurrent respratory dsease should not be employed n any process n whch ths product s used. Do not get n eyes or on skn or clothng. Do not ngest. Use only wth adequate ventlaton. Wear approprate resprator whenventlatonsnadequate., } J Preventon of fre and exploson: Avod contact wth heat and gnton sources and wth strong oxdzng agents. Precautons whle movng the product: Keep n the orgnal contaner or an approved alternatve made from a compatble materal, kept tghtly closed when not n use. Empty contaners retan product resdue and canbe hazardous. Hygene Measures: Workers should wash hands and face before eatng, drnkng and smokng. 7.2 Condtons for safe storaae. ncludng anv ncompatbltes Techncal measures: Store n accordance wth local regulatons. Store n orgnal contaner protected from drect sunlght n a dry, cool and well ventlated area, away from ncompatble materals (see secton0) and food and drnk. Use approprate contanment to avod envronmental contamnaton. Storage precautons: Keep contaner tghtly closed and sealed untl ready for use. Contaners that have been opened must be carefully resealed and kept uprght to prevent leakage. Do not store n unlabelled contaners. Eatng, drnkng and smokng should be prohbted n areas where ths materal s handled, stored and processed. Remarks: Avod all possble sources of gnton(spark or fame). Take precautonary measures aganst electrostatc dscharges.

7 SAFETY DATA SHEET Substance Name: PHTHALC ANHYDRDE Page 7 of 4 ncompatble products: Avod contact wth strong oxdzng agents, amnes and strong bases. Packagng materals: Recommended: Use orgnal contaner. 7.3 Specfc end use(s): Secton 8: EXPOSURE CONTROL / PERSONAL PROTECTON 8. Rsk management measures OccupatonalExposure Controls: Techncal measures: Use only wth adequate ventlaton. f user operatons generate dust, fumes, gas, vapour or mst, use process enclosures, local exhaust ventlaton or other engneerng controls to keep worker exposure to arborne contamnants below any recommended or statutory lmts. Occupatonal Exposure Lmts: Refer to the CSR. Derved No Effect Level (DNELf r { \ ~ \! Exposure Pattern Route Workers General Populaton Long-term - systemc effects Oral N/A 5 mg/kg bw/day Long-term - systemc effects Dermal 0 mg/kg bw/day 5 mg/kg bw/day Long-term - systemc effects nhalaton 35.2 mg/m3 8.6 mg/m3 Predcted No EHect Concentraton /PNEC\ PNEC freshwater mg/ PNEC ntermttent 5.6 mg/ PNEC marne water 0. mg/ PNEC sedment freshwater 3.80 mg/kg wwt PNEC sedment marne water 0.38 mg/kg wwt PNEC sewage treatment plant 0 mg/ 8.2 Exposure controls Enaneerna Controls Recommended montorng procedures: f ths product contans ngredents wth exposure lmts, personal, workplace atmosphere or bologcal montorng may be requred to determne the effectveness of the ventlaton or other control measures and/or the necessty to use respratory protectve equpment. Reference should be made to European Standard EN 689 for methods for the assessment of exposure by nhalaton to chemcal agents and natonal gudance documents for methods for the determnaton of hazardous substances.

8 Substance Name: PHTHALC ANHYDRDE Page 8 of 4 Person Protectve measures Respratory protecton: Use a properly ftted, ar-purfyng or ar-fed resprator complyng wth an approved standard f a rsk assessment ndcates ths s necessary. Resprator selecton must be based on known or antcpated exposure levels, the hazards of the product and the safe workng lmts of the selected resprator. Recommended: n case of dust formaton partcle flter P2. Eye protecton: Safety eyewear complyng wth an approved standard should be used when a rsk assessment ndcates ths s necessary to avod exposure to lqud splashes, msts, gases or dusts. Recommended: Tghtly fttng safety goggles. Skn protecton Hand protecton: Sold Materal: Chemcal-resstant, mpervous gloves complyng wth an approved standard should be worn at al tmes when handlng chemcal products f a rsk assessment ndcates ths s necessary. After contamnaton wth product change the gloves mmedately and dspose of them accordng to relevant natonal andlocal regulatons. <hour (breakthrough tme): use Ntrle rubber - NBR gloves. Lqud (Molten) Materal: Chemcal-resstant, mpervous gloves or gauntlets complyng wth an approved standard should be worn at all tmes when handlng chemcal products f a rsk assessment ndcates ths s necessary. After contamnaton wth product change the gloves mmedately and dspose of them accordng to relevant natonal and local regulatons. < hour (breakthrough tme): use PVC or Rubber gloves. : Skn and body (other than the hands): Personal protectve equpment for the body should be selected based on the task beng performed and the rsks nvolved and should be approved by a specalst before handlng ths product. Recommended: chemcal-resstant protectve sut. Hyqenc measures: W ash hands, forearms and face thoroughly after handlng chemcal products, before eatng, smokng and usng the lavatory and at the end of the workng perod. Approprate technques should be used to remove potentally contamnated clothng. Wash contamnated clothng before re-usng. Ensure that eyewash statons and safety showers are close to the workstatonlocaton. Envronmental exposure controls: Techncal measures: Emssons from ventlaton or work process equpment should be checked to ensure they comply wth the requrements of envronmental protecton legslaton. n some cases, fume scrubbers, flters or engneerng modfcatons to the process equpment may be necessary to reduce emssons to acceptable levels. Secton 9: PHYSCAL AND CHEMCAL PROPERTES Generalnformaton Physcal state: Sold Colour: Whte Odour: Not avalable Molecular weght: 48.2

9 / Substance Name: PHTHALC ANHYDRDE Page 9 of 4 Safety data ph: Not avalable Bolng pont/bolng range: 284.5V at 03 hpa. Auto-gnton temperature: 580oC Flash pont: 52oC Flammablty: Non flammable sold. Explosve propertes: Non explosve. Oxdzng propertes: Not oxdzng. Vapor pressure (hpa, 26.6'C): Relatve densty:.527 g*cm-3 at 20.C Water solublty: mg/ (substance s hydrolytcally unstable at ph 4, 7 and 9). Solublty n organc solvents: Substance s soluble n formc acd (470 g/ at 20'C) and soluble n carbon dsulfde. Log partton coeffcent n-octanol / Water:.60 at 20V Vscosty (Dynamc):.9 mpa*s at 32'C,.25 mpa*s at 55'C. Vapour densty: Sold materal Evaporaton rate (n-butyl acetate=): Sold materal \ Other nformaton: Me/tngpont / meltngrange: 3.6oC Surface tenson: sold materal Granulometry: N/A Dssocaton constants (of Phthalc acd): pkal = 2.97, pka2 = 5.43 at 35'C. Secton 0: STABLTY AND REACTVTY 0. Stabltv The product s stable at normal storage, handlng and use temperatures. 0.2 Condtons to avod Heat, sparks, gnton ponts, names, statc electrcty. 0.3 Materals to avod Keep away from water, alkals, alcohols, oxygen, oxdzng agents, acds, ntrte, Metallc oxdes. The substance s ar senstve. 0.4 Hazardous Decomposton products Under normal condtons of storage and use, hazardous decompostonproducts should not be produced. ncomplete combuston and thermolyss produce potentally toxc gases such as: carbon monoxde, carbon doxde and soot. 0.5 Hazard polymerzaton: N/A

10 Substance Name: PHTHALC AMHYOROE Page 0 of 4 Secton : TOXCOLOGCAL NFORMATON. nformaton ontoxcoloacal effects Acute toxcty by oral route, nhalaton and dermal route: Phthalc anhydrde s classfed under Annex of Dr 67/548/EEC as X, R22 - Harmful f swallowed, wth correspondng classfcaton under CLP of H302 - Harmful f swallowed. Product / ngredent name Phthalc Anhydrde Test Speces Does LD5O, Oral Rat (male),530 mg/kg bw LC5O, dscrmnatng dose,nhalaton Rat (male/female) 3,60 mg/m3 ar 3! LD5O, dscrmnatng dose, Dermal Rabbt 3,60 mg/kg bw Skn rrtaton / corroson: rrtatng. Eye rrtaton: rrtatng / Skn 6en6tzaton: Senstzng. Reepratory eenetzaton: Senstzng. Repeated dose toxcty - Oral route: NOAEL: 500 mg/kg body weght/day. CMR Effects: Ì Mutagencty: Genetc toxcty: Negatve. Carcnogencty: No evdence of carcnogencty was seen. Oral route - NOAEL: 000 mg/kg body weght/day. Reproductve toxcty: weghtday. No evdence of toxcty to reproductve organs. NOAEL:,000 mg/kg body Developmental toxcty: bw/day. Phthalc anhydrde s not a developmental toxcant. NOAEL:,700 mg/kg Toxcoknetca: Upon exposure to Phthalc anhydrde, the materal s easly hydrolyzed to Phthalc acd, whch s secreted. No evdence of conjugate formaton. The half-lfe of Phthalc acd was not determned. Chronc/Other _Effects: No relevant addtonal data s avalable.

11 / 4 " SAFETY DATA SHEET Substance Name: PHTHALC ANHYDRDE Page of 4 Secton 2: ECOLOGCAL NFORMATON General Remark on Ecotoxcty Testng: Phthalc anhydrde reacts rapdly wth water, formng phthalc acd. Snce the half-lfe of phthalc anhydrde n water s n the range of seconds to mnutes, vrtually tests wth phthalc anhydrde n aquatc solutons measure effects of phthalc acd rather than phthalc anhydrde. Consequently, phthalc acd can also be used as the test substance to evaluate the aquatc effects of phthalc anhydrde. Substance name Toxcty to ash Toxcty to nvertebrates Toxcty to algae/ terrestral plants Toxcty to other aquatc organsms Other data (brds, bees, plants etc.)! Phthalc Anhydrde LC5O/ 7 days: 560 mg/ (Dano rero) Long term result: NOEC 0 mg/ (Oncorhynchus myk!ss) EC5o / 48H; >640 mg/ (Daphna magna) Long term result: EC5o / 2 days: 0 mg/ (based on reproducton, may be a pheffect). (Daohna maana\ EC5o/72H: >00 mg/ (Desmodesmus subspculatus) EC5o / 3 days: 73 mg/ at ph=2.80 (based on frut germnaton). (Lactuca salva) Amphban: LCD/24H: 224 mg/ (Bufo bufo japoncus) N/A :! ~ " t Actvated sludge nhbton of oxygen consumptontestng (SO 892). EC5o (3hr): > 000 mg/ Moblty n sol: Adsorpton/desorpton - The substance does not adsorb to sedments and suspended solds, as the expermental Koc of 3 suggests that phthalc acd has a hgh moblty n sol. Persstence andoearadabtv Botc - Phthalc anhydrde and the hydrolyss product phthalc acd are readly bodegradable. ^botc Photodegradaton n ar - An atmospherc half-lfe of 2.4 days for phthalc anhydrde and 3 days for phthalc acds estmated for ndrect photodegradaton. Oegradaton products: not measured. Photodegradaton n water - n the hydrosphere, phthalc anhydrd s transformed photochemcally under anaerobc condtons showng polymerzaton to polyphenyl. The half-lfe s n the range from hours. For photo-oxdaton n sea water a half-lfe of 0.93 hours s obtaned. Hydrolyss - Phthalc anhydrde hydro/yses by 50 % wthn 30.5 seconds n the presence of water at ph7 and25oc, formng phthalc acd. Boaccumulatve potental: Phthalc anhydrde has low potental to boaccumulate based on a log Kow of.6 (BCF s calculated to be 3.4). The hydrolyss product, phthalc acd, has a calculated BCF of 3.6, ands also has a low potental to boaccumulate. Secondary posonng: Rsk characterzaton s not requred, because the substance s readly bodegradable and rsk of boaccumulaton s low.

12 Substance Name: PHTHALC ANHYDRDE Page2 of 4 Result of PBT/vPvB assessment (f CSR s requred): Phthalc anhydrde and ts hydrolyss product Phthalc acd are nether a PBT nor a vpvb substance. Other adverse effects: N/A Secton 3: DSPOSAL CONSDERATONS 3.Methods of dsposal Examne possbltes for re-utlzaton. Product resdues and un-cleaned empty contaners should be packaged, sealed, labeled, and dsposed of or recycled accordng to relevant natonal and local regulatons. W here large quanttes are concerned, consult the suppler. When un-cleaned empty contaners are passed on, the recpent must be warned of any possble hazard that may be caused by resdues. For dsposal wthn the EC, the approprate code accordng to the European Waste Lst (EWL) should be used. t s among the tasks of the polluter to assgn the waste to waste codes specfc to ndustral sectors and processes accordng to the European Waste Lst (EWL). 3.2 Hazardous waste The classfcaton of the product may meet the crtera for a hazardous waste. T Secton 4: TRANSPORT NFORMATON 4. Land Transportaton (ADR/RD\ / nland Waterwav Transport (AND(R)` UNnumber: Not regulated as a hazardous materal Proper shppngname: PHTH&LfC ANHYDRDE ~ 4.2 Marne Transport (MDG) UN number: Not regulated as a hazardous materal Proper shppng name: PHTHALC ANHYDRDE Envronmental Hazard: No 4.3 Ar Transport (CAO/ATA) UNnumber: Not regulated as a hazardous materal Proper shppngname: PHTHKLC-ANHYD- RlD- E ~ 4.4 f shpped n molten form: Land Transportaton (ADR/RD) / nland Waterwav Transport (AND(R)) / Marne Transport (MDG) UN number: 3256 Proper shppngname: ELEVATED TEMPERATURE LQUD, N.O.S Chemcal name: PHTHALC ANHYDRDE Hazard class: Packng group: ADR/RD-Labels: 3 3 (Nammable lqud)

13 Substance Name: PHTHALC ANHYDRDE Page 3 of 4 Marne Transport (MDG) UN number: 3256 Proper shppng name: ELEVATED TEMPERATURE LQUD, Flammable N.O.S (Phthalc anhydrde) Hazard class: 3 Packng group: EmS number: Labels: 3 Envronmental Hazard: No Ar Transport (CAO/ATA) Not allowed. F-E, S-D.Natonal Fre Protecton AssocatonHazard Ratngs- NFPA (R): Health Hazard - 2 Flammablty - Reactvty - Secton 5: REGULATORY NFORMATON 5. Safetv. health and envronmental reaulatons/leaslaton specfc for the substance or mxture EU Drectves 67/548/EEC and 999/45/EC (ncludng amendments) and take nto account the ntended product use. EU Regulaton (EC) No.907/2006 (REACH) EU Regulaton (EC) No 272/2008 (CLP) 5.2 Chemcal safetv assessment n accordance wth REACH artcle 4, a Chemcal Safety Assessment has been carred out for ths substance. Secton 6: OTHER NFORMATON Full text of R-phrases referred to n sectons 2 and 3: R22 "Harmful f swallowed R37/38 - rrtatng to respratory system and skn R4 - Rsk of serous damage to eyes R42/43 - May cause senstzaton by nhalaton and skn contact Safety phrases: SO2 - Keep out of the reach of chldren Do not breathe vapour / spray S22 ' - Do not breathe dust. S24/25 - Avod contact wth skn and eyes S26 - n case of contact wth eyes, rnse mmedately wth plenty of water and seek medcal advce. 537/39 - Wear sutable gloves and eye/face protecton S46 - f swallowed, seek medcal advce mmedately and show ths contaner or label

14 / SAFETY DATA SHEET Substance Name: PHTHALC ANHYDRDE Page 4 of 4 Full text of Hazards Statements referred to n sectons 2 and 3: H302 - Harmful f swallowed. H335 - May cause respratory rrtaton. H35 - Causes skn rrtaton. H38 - Causes serous eye damage. H334 - May cause allergy or asthma symptoms or breathng dffcultes f nhaled. H37 - May cause an allergc skn reacton. Precautonary Statements: P232 - Protect product from mosture P26 - Avod breathng dust. P264 - Wash hands thoroughly after handlng. P280 - Wear protectve gloves/protectve clothng/eye protecton/face protecton. P3O+P32 - F SWALLOWED: call a POSON CENTER or doctor / physcan f you feel unwell. P302+P352 - F ON SKN: Wash wth plenty of soap and water. P305+P35+P338 - F NEYES: Rnse cautously wth water for several mnutes. Remove contact lenses, f present and easy to do. Contnue rnsng. P337+P33 - F eyesrrtaton occurs: Get medcal advce/attenton. P402+P233 - Store n a well-ventlated place. Keep contaner tghtly closed.!'! ~ Tranng advce: Before usng/handlng the product one must read carefully present MSDS. Recommended restrcton: N/A Key Legend nformaton: ACGH- Amercan Conference of Governmental ndustral Hygensts OSHA- Occupatonal Safety and Health Admnstraton NTP- Natonal Toxcology program ARC- nternatonal Agency for Research on Cancer ND- Not Determned N/A- Not avalable R-phrases- Rsk phrases S-phrases- Safety phrases H-statements - Hazard statements P-statements - Preoautonary statements Verson no. Date of ssue: 30/08/20