Reagent R1, Reagent R2, Reagent R3, Diluent, Calibrators and Controls
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1 Date of issue: 06/05/2015 Date of Revision: 06/08/2015 Revision: B SECTION 1 Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form Product name Product code Mixture 25-OH Vitamin D Assay Reagent R1, Reagent R2, Reagent R3, Diluent, Calibrators and Controls DZ688C, 1.2. Relevant identified uses of the substance or mixture and uses advised against 1.3. Details of the supplier of the safety data sheet Supplier: Diazyme Laboratories Gregg Court Poway, CA T DZ688C-R1, DZ688C-R2, DZ688C-R3, DZ688C-R4, DZ688C-CAL, DZ688C-CON Authorized Representative: MDSS GmbH Schiffgraben 41 Germany (+49) Emergency telephone number Emergency number SECTION 2 Hazards identification 2.1. Classification of the substance or mixture Classification (GHS-US) Dimethyl Sulfoxide Applicable to Reagent R1 only CAS: Contact your local health authority or poison control center in an emergency. Manufacturer contact number for the US is as follows: (858) Flam. Liq. 4 H227 Full text of H-phrases: see section Label elements GHS-US labeling Signal word (GHS-US) Hazard statements (GHS-US) Precautionary statements (GHS-US) Warning H227 - Combustible liquid P210 - Keep away from heat/sparks/open flames/hot surfaces. - No smoking P280 - Wear protective gloves/protective clothing/eye protection/face protection P370+P378 - In case of fire: Use... to extinguish P403+P235 - Store in a well-ventilated place. Keep cool P501 - Dispose of contents/container to Other hazards (for all components) 2.4. Unknown acute toxicity (GHS-US) SECTION 3 Composition/information on ingredients 3.1. Substance 3.2. Mixture 06/05/2015 SDS 1082 Rev B EN (English US) Page 1
2 Name Product identifier % Classification (GHS-US) Flam. Liq. 4 H227 Dimethyl Sulfoxide (DMSO) (CAS No) (Reagent R1 only) Full text of H-phrases: see section 16 SECTION 4 First aid measures 4.1. Description of first aid measures First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact First-aid measures after ingestion Remove person to fresh air and keep comfortable for breathing. Wash skin with plenty of water. Rinse eyes with water as a precaution. Call a poison center/doctor/physician if you feel unwell Most important symptoms and effects, both acute and delayed 4.3. Indication of any immediate medical attention and special treatment needed Treat symptomatically. SECTION 5 Firefighting measures 5.1. Extinguishing media Suitable extinguishing media 5.2. Special hazards arising from the substance or mixture Fire hazard Reactivity 5.3. Advice for firefighters Protection during firefighting SECTION 6 Accidental release measures Water spray. Dry powder. Foam. Carbon dioxide. Combustible liquid Personal precautions, protective equipment and emergency procedures For non-emergency personnel Emergency procedures For emergency responders Protective equipment 6.2. Environmental precautions Avoid release to the environment Methods and material for containment and cleaning up Methods for cleaning up Other information The product is non-reactive under normal conditions of use, storage and transport. Do not attempt to take action without suitable protective equipment. Self-contained breathing apparatus. Complete protective clothing. Ventilate spillage area. No open flames, no sparks, and no smoking. Do not attempt to take action without suitable protective equipment. For further information refer to section 8: "Exposure controls/personal protection". Take up liquid spill into absorbent material. Notify authorities if product enters sewers or public waters. Dispose of materials or solid residues at an authorized site Reference to other sections For further information refer to section 13. SECTION 7 Handling and storage 7.1. Precautions for safe handling Precautions for safe handling Hygiene measures Ensure good ventilation of the work station. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Wear personal protective equipment. Do not eat, drink or smoke when using this product. Always wash hands after handling the product Conditions for safe storage, including any incompatibilities Storage conditions Store in a well-ventilated place. Keep cool Specific end use(s) 06/05/2015 SDS 1082 Rev B EN (English US) 2/1
3 SECTION 8 Exposure controls/personal protection 8.1. Control parameters 25-OH Vitamin D Assay ACGIH OSHA 8.2. Exposure controls Appropriate engineering controls Hand protection Eye protection Skin and body protection Respiratory protection Environmental exposure controls SECTION 9 Physical and chemical properties Ensure good ventilation of the work station. Protective gloves. Safety glasses Information on basic physical and chemical properties Physical state Color Odor Odor threshold ph Melting point Freezing point Boiling point Flash point Relative evaporation rate (butyl acetate=1) Flammability (solid, gas) Explosion limits Explosive properties Oxidizing properties Vapor pressure Relative density Relative vapor density at 20 C Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. Avoid release to the environment. Liquid Mixture contains one or more component(s) which have the following colour(s): Colourless Colourless to white White There may be no odour warning properties, odour is subjective and inadequate to warn of overexposure. Mixture contains one or more component(s) which have the following odour(s): Odourless Almost odourless Garlic odour Solubility Water Solubility in water of component(s) of the mixture : : : 42 g/100ml : 100 g/100ml : : 100 g/100ml : 12 g/100ml Log Pow Log Kow Auto-ignition temperature Decomposition temperature Viscosity Viscosity, kinematic Viscosity, dynamic 9.2. Other information SECTION 10 Stability and reactivity Reactivity The product is non-reactive under normal conditions of use, storage and transport Chemical stability Stable under normal conditions. 06/05/2015 SDS 1082 Rev B EN (English US) 3/1
4 10.3. Possibility of hazardous reactions No dangerous reactions known under normal conditions of use Conditions to avoid Avoid contact with hot surfaces. Heat. No flames, no sparks. Eliminate all sources of ignition Incompatible materials Hazardous decomposition products Under normal conditions of storage and use, hazardous decomposition products should not be produced. SECTION 11 Toxicological information Information on toxicological effects Acute toxicity Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity (single exposure) Specific target organ toxicity (repeated exposure) Aspiration hazard SECTION 12 Ecological information Toxicity Ecology - general The product is not considered harmful to aquatic organisms or to cause long-term adverse effects in the environment Persistence and degradability Bioaccumulative potential Mobility in soil Other adverse effects Effect on the global warming No known ecological damage caused by this product. SECTION 13 Disposal considerations Waste treatment methods Waste treatment methods Dispose of contents/container in accordance with licensed collector s sorting instructions. SECTION 14 Transport information Department of Transportation (DOT) Applicable to Reagent R2, Reagent R3 and Diluent only In accordance with DOT Transport document description UN1687 Sodium azide, 6.1, II UN-No.(DOT) UN1687 Proper Shipping Name (DOT) Sodium azide Transport hazard class(es) (DOT) Class Poisonous materials 49 CFR Hazard labels (DOT) Poison inhalation hazard Packing group (DOT) II - Medium Danger 06/05/2015 SDS 1082 Rev B EN (English US) 4/1
5 DOT Packaging Non Bulk (49 CFR 173.xxx) 212 DOT Packaging Bulk (49 CFR 173.xxx) 242 DOT Special Provisions (49 CFR ) DOT Packaging Exceptions (49 CFR 173.xxx) 153 DOT Quantity Limitations Passenger aircraft/rail (49 CFR ) DOT Quantity Limitations Cargo aircraft only (49 CFR ) DOT Vessel Stowage Location DOT Vessel Stowage Other Additional information Other information IB8 - Authorized IBCs: Metal (11A, 11B, 11N, 21A, 21B, 21N, 31A, 31B and 31N); Rigid plastics (11H1, 11H2, 21H1, 21H2, 31H1 and 31H2); Composite (11HZ1, 11HZ2, 21HZ1, 21HZ2, 31HZ1 and 31HZ2); Fiberboard (11G); Wooden (11C, 11D and 11F); Flexible (13H1, 13H2, 13H3, 13H4, 13H5, 13L1, 13L2, 13L3, 13L4, 13M1 or 13M2). IP2 - When IBCs other than metal or rigid plastics IBCs are used, they must be offered for transportation in a closed freight container or a closed transport vehicle. IP4 - Flexible, fiberboard or wooden IBCs must be sift-proof and water-resistant or be fitted with a siftproof and water-resistant liner. 25 kg 100 kg A - The material may be stowed on deck or under deck on a cargo vessel and on a passenger vessel Stow away from heavy metals and their compounds,52 - Stow separated from acids,91 - Stow separated from flammable liquids No supplementary information available. ADR Transport by sea UN-No. (IMDG) 1687 Proper Shipping Name (IMDG) SODIUM AZIDE Class (IMDG) Toxic substances Packing group (IMDG) II - substances presenting medium danger Air transport UN-No. (IATA) 1687 Proper Shipping Name (IATA) Sodium azide Class (IATA) Toxic Substances Packing group (IATA) II - Medium Danger SECTION 15 Regulatory information US Federal regulations International regulations CANADA EU-Regulations Classification according to Regulation (EC) No. 1272/2008 [CLP] Classification according to Directive 67/548/EEC [DSD] or 1999/45/EC [DPD] National regulations US State regulations SECTION 16 Other information Full text of H-phrases Flam. Liq. 4 Flammable liquids Category H227 Combustible liquid SDS US Diazyme 06/05/2015 SDS 1082 Rev B EN (English US) 5/1
6 This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product 06/05/2015 SDS 1082 Rev B EN (English US) 6/1
Date of issue: 05/31/2015 Date of Revision: 06/04/2015 Revision: C. Reagent R1, Reagent R2, Calibrators and Controls
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