qscript XLT cdna SuperMix MATERIAL SAFETY DATA SHEET

Transcription

1 Page 1 of 9 SECTION 1 PRODUCT AND COMPANY IDENTIFICATION Product Identifier: qscript XLT cdna SuperMix Product Code(s): Catalog numbers: , , General Use: Laboratory reagent MSDS Issue Date: 16 June, 2014 For Research Use Only, Not for Use in Diagnostic Procedures Manufacturer: QUANTA BIOSCIENCES INC. 202 PERRY PKWY., SUITE 1 GAITHERSBURG, MD USA Phone: (800) FAX: (301) technical.support@quantabio.com Emergency Telephone: Quanta BioSciences: (240) (09:00 to 17:00 EST) Or contact your local distributor for Quanta BioSciences products. SECTION 2 HAZARDS IDENTIFICATION GHS Classification Not a hazardous substance or mixture. GHS Label element Not a hazardous substance or mixture. Potential Health Effects Aggravated Medical Condition: Symptoms of Overexposure: None known. No information availbale Carciniogenicity: IARC ACGIH OSHA NTP No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.

2 Page 2 of 9 SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS Hazardous Ingredients CAS Registry No. Percentage (wt/wt) glycerol magnesium chloride, hexahydrate ammonium chloride SECTION 4 FIRST AID MEASURES General advice If inhaled In case of skin contact In case of eye contact If swallowed Most important symptoms and effects, both acute and delayed Notes to physician Show this safety data sheet to the doctor in attendance. Move to fresh air. If symptoms persist, call a physician. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. If symptoms persist, call a physician. Remove contact lenses. Protect unharmed eye. Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If accidentally swallowed obtain immediate medical attention. Rinse mouth with water. Never give anything by mouth to an unconscious person. No information available. No information available. SECTION 5 FIRE FIGHTING MEASURES Suitable extinguishing media Specific hazards during firefighting Hazardous combustion products Specific extinguishing methods Further information Special protective equipment for firefighters Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Exposure to decomposition products may be a hazard to health. No hazardous combustion products are known In the event of fire and/or explosion do not breathe fumes. Wear self contained breathing apparatus for fire fighting if necessary.

3 Page 3 of 9 SECTION 6 ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures METHODS FOR CLEANING UP: Use personal protective equipment. See Section 8. Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. Keep in suitable, closed containers for disposal SECTION 7 HANDLING AND STORAGE Advice on safe handling Materials to avoid Storage For personal protection see section 8. Smoking, eating and drinking should be prohibited in the application area. Do not store near acids. Store at -20 C in closed original container. Keep away from food, drink and animal feeding stuffs. Store away from incompatible materials. SECTION 8 EXPOSURE CONTROLS / PERSONAL PROTECTION Components CAS-No. Value type (Form of exposure) Control Basis parameters / Permissible concentration 5 mg/m3 OSHA Z-1 glycerol TWA (mist, respirable fraction) TWA (mist, total 15 mg/m3 OSHA Z-1 dust) TWA (Total) 10 mg/m3 OSHA P0 TWA (Respirable 5 mg/m3 OSHA P0 fraction) TWA 10 mg/m3 ACGIH ammonium TWA 10 mg/m3 ACGIH chloride STEL 20 mg/m3 ACGIH TWA (Fumes) 10 mg/m3 NIOSH REL ST (Fumes) 20 mg/m3 NIOSH REL TWA 10 mg/m3 OSHA P0 STEL 20 mg/m3 OSHA P0

4 Page 4 of 9 Personal protective equipment Hand protection Remarks: Eye Protection: Skin and body protection: Hygiene measures: The choice of an appropriate glove does not only depend on its material but also on other quality features and is different from one producer to the other. Take note of the information given by the producer concerning permeability and break through times, and of special workplace conditions (mechanical strain, duration of contact Gloves Safety glasses. Choose body protection according to the amount and concentration of the dangerous substance at the work place. Footwear protecting against chemicals. Keep away from food and drink. When using do not eat, drink or smoke. SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES Appearance Colour Odour Odour Threshold ph Melting point/range Flash Point Evaporation rate Burning rate Upper explosion limit Lower explosion limit Vapour pressure Relative vapour density Relative density Density Solubility(ies) Water solubility Solubility in other solvents Partition coefficient: n-octanol/water Auto-ignition temperature Thermal decomposition Viscosity Viscosity, dynamic Viscosity, kinematic Explosive properties Oxidizing properties liquid clear 8.3 (22ºC) Completely soluble

5 Page 5 of 9 SECTION 10 STABILITY AND REACTIVITY Reactivity: Chemical stability: Possibility of hazardous reactions: Conditions to avoid: Incompatible materials Hazardous decomposition products No decomposition if stored and applied as directed. No decomposition if stored and applied as directed. Stable under recommended storage conditions. Hazardous decomposition products formed under fire conditions. No data available No data available No decomposition if stored and applied as directed SECTION 11 TOXICOLOGICAL INFORMATION Acute Toxicity Acute oral toxicity Acute inhalation toxicity Acute dermal toxicity : : : Components: glycerol: Acute oral toxicity Acute dermal toxicity : LD50 Oral rat: mg/kg : LD50 dermal rabbit: mg/kg magnesium chloride, hexahydrate: Acute oral toxicity : LD50 Oral rat: mg/kg ammonium chloride Acute oral toxicity : LD50 Oral rat: mg/kg Skin corrosion/irritation May cause skin irritation in susceptible persons Components: glycerol: Species/: rabbit Exposure time: 24 hours Result: mild skin irritation Serious eye damage/eye irritation

6 Page 6 of 9 Remarks: May irritate eyes Components: glycerol: Species/: rabbit Exposure time: 24 hours Result: mild eye irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity Reproductive toxicity STOT - single exposure STOT - repeated exposure Aspiration toxicity Further information SECTION 12 ECOLOGICAL INFORMATION Ecotoxicity Toxicity to fish Toxicity to algae Toxicity to bacteria Components: glycerol: Toxicity to fish ammonium chloride: Toxicity to fish : : : :LC50 (Leuciscus idus (golden orfe)): >250 mg/l Exposure time: 48 hours :LC50 (Ceriodaphnia (water flea)): 209mg/l Exposure time: 96 hours LC50 (Oncorhynchus mykiss (rainbow trout)): 3.98 mg/l Exposure time: 96 hours Toxicity to daphnia and other aquatic invertebrates EC50 (Daphnia magna (Water flea)): 161 mg/ Exposure time: 48 hours Persistence and degradability

7 Page 7 of 9 No data available Bioaccumulative potential Bioaccumulation Partition coefficient: n-octanol/water : : Mobility in soil Other adverse effects SECTION 13 DISPOSAL CONSIDERATIONS Disposal methods Contaminated packaging : Empty containers should be taken to an approved waste handling site for recycling or disposal SECTION 14 TRANSPORT INFORMATION UNRTDG Not regulated as a dangerous good IATA-DGR Not regulated as a dangerous good IMDG-Code Not regulated as a dangerous good Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code National Regulations 49 CFR Not regulated as a dangerous good Special precautions for user Remarks Not classified as dangerous in the meaning of transport regulations SECTION 15 REGULATORY INFORMATION OSHA Hazards Harmful by ingestion EPCRA Emergency Planning and Community Right-to-Know Act CERCLA Reportable Quantity Components CAS-No. Component RQ (lbs) ammonium chloride SARA 304 Extremely Hazardous Substances Reportable Quantity This material does not contain any components with a section 304 EHS RQ.

8 Page 8 of 9 SARA 311/312 Hazards SARA 302 SARA 313 : No SARA Hazards : SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. : SARA 313: this material does not contain any chemical components with known CAS numbers that exceed the threshold (De Miniis) reporting levels established by SARA Title III, Section 313. Clean Air Act The following chemical(s) are listed as HAP under the U.S. Clean Air Act, Section 12 (40 CFR 61): This product does not contain any chemicals listed under the U.S. Clean Air Act Section 112(r) for Accidental Release Prevention (40 CFR , Subpart F).The following chemical(s) are listed under the U.S. Clean Air Act Section 111 SOCMI Intermediate or Final VOC's (40 CFR ): Glycerol Clean Water Act The following Hazardous Substances are listed under the U.S. Clean Water Act, Section 311, Table 116.4A: ammonium chloride The following Hazardous Chemicals are listed under the U.S. Clean Water Act, Section 311, Table 117.3: ammonium chloride This product does not contain any toxic pollutants listed under the U.S. Clean Water Act Section 307 U.S. State Regulations California Proposition 65 - This product contains the following Proposition 65 chemicals: None This product has been classified according to the hazard criteria of the CPR and the MSDS contains all of the information required by the CPR. WHMIS Hazard class: D2B SECTION 16 OTHER INFORMATION MSDS Status: Version 1.0 Original NFPA:

9 Page 9 of 9 This material is sold for research and development purposes only. It is not for any human or animal therapeutic or clinical diagnostic use. It is not intended for food, drug, household, agricultural, or cosmetic use. An individual technically qualified to handle potentially hazardous chemicals must supervise the use of this material. The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. qscript is a trademark of Quanta BioSciences, Inc.