Material Safety Data Sheet

Transcription

1 Creation Date: Revision Date: Material Safety Data Sheet 1 Chemical Product and Company Identification Material Name Relaxin-3 (h) [125I] Version # 01 CAS # Mixture Item # NEX418010UC Identification Of The Company/Undertaking Emergency Telephone Number Hazardous component(s) PerkinElmer Life and Analytical Sciences 710 Bridgeport Avenue Shelton, CT Technical Support CHEMTREC Emergency Phone Composition / Information on Ingredients CAS # Percent PEL TLV ppm 20 1-PROPANOL ppm 200 Non-hazardous component(s) CAS # Percent WATER Other components below reportable levels 3 Hazards Identification Potential Short Term Health Effects Skin This product may be harmful if it is absorbed through the skin Eyes Contact may irritate or burn eyes Inhalation May cause irritation of respiratory tract Ingestion Do not ingest Target Organs Eyes Kidney Liver Blood Central nervous system 4 First Aid Measures General advice If you feel unwell, seek medical advice (show the label where possible) First Aid Skin contact Rinse with water Consult a physician 1 / 5

2 Eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician Inhalation Move to fresh air Oxygen or artificial respiration if needed Get medical attention immediately Ingestion If swallowed, seek medical advice immediately and show this container or label Have victim rinse mouth thoroughly with water 5 Fire Fighting Measures Suitable extinguishing media Do not use a solid water stream as it may scatter and spread fire Use extinguishing measures that are appropriate to local circumstances and the surrounding environment Carbon dioxide (CO2) Dry chemical Specific methods In the event of fire, cool tanks with water spray Water mist may be used to cool closed containers 6 Accidental Release Measures Personal precautions Use personal protective equipment Keep people away from and upwind of spill/leak Environmental precautions Prevent further leakage or spillage if safe to do so Methods for cleaning up Dam up Soak up with inert absorbent material Containment Procedures Stop the flow of material, if this is without risk Dike the spilled material, where this is possible Prevent entry into waterways, sewers, basements or confined areas 7 Handling and Storage Handling Keep away from heat and sources of ignition Handle and open container with care Storage Use care in handling/storage 8 Exposure Controls / Personal Protection Exposure Limit Values ACGIH - Threshold Limits Values - Time Weighted Averages (TLV-TWA) 1-PROPANOL ppm TWA ppm TWA OSHA - Final PELs - Time Weighted Averages (TWAs) 1-PROPANOL ppm TWA; 500 mg/m3 TWA ppm TWA; 70 mg/m3 TWA Exposure Controls Engineering measures to reduce exposure Provide adequate ventilation Provide adequate local exhaust ventilation to maintain worker exposure below exposure limits Hygiene measures Handle in accordance with good industrial hygiene and safety practice 2 / 5

3 Respiratory protection In the case of respirable dust and/or fumes, use self-contained breathing apparatus Wear a positive-pressure supplied-air respirator Eye protection If splashes are likely to occur, wear: goggles Avoid contact with eyes 9 Physical & Chemical Properties General Information Form Liquid Important health, safety and environmental information Flash Point Auto Ignition Flammability Class Boiling Point Melting Point Vapor Pressure Volatile Organic Stability No hazards to be especially mentioned Incompatibility 428 F (6 C) estimated 7331 F (3895 C) estimated Flammable IB 1789 F (816 C) estimated F (-127 C) estimated hpa estimated 50 % estimated 10 Chemical Stability & Reactivity Information Strong oxidizing agents Further information Stable at normal conditions 11 Toxicological Information Acute Toxicity NIOSH - Selected LD50s and LC50s 1-PROPANOL Oral LD50 Rat: 1870 mg/kg; Oral LD50 Mouse: 6800 mg/kg; Dermal LD50 Rabbit: 4060 mg/kg Inhalation LC50 Rat: 7551 ppm/8h; Inhalation LC50 Mouse: 2693 ppm/1h; Oral LD50 Rat: 2460 mg/kg; Oral LD50 Mouse: 269 mg/kg; Dermal LD50 Rabbit: 1250 µl/kg Carcinogenicity Data Ingredient(s) 1-PROPANOL - ACGIH Animal Carcinogen - ACGIH Not Classified Carcinogen ACRYLONITRILE - OSHA Select Carcinogen - OSHA Possible Select Carcinogen - ACGIH Animal Carcinogen - NTP Suspected Carcinogen 3 / 5

4 Symptoms and Target Organs NIOSH - Pocket Guide - Target Organs 1-PROPANOL skin, eyes, respiratory system, GI tract, CNS kidneys, liver, CVS, CNS, respiratory system Further information Not available 12 Ecological Information Ecotoxicity Ecotoxicity - Freshwater Fish Species Data 1-PROPANOL Hr LC50 fathead minnow: 4480 mg/l (flow-through) Hr LC50 fathead minnow: 1640 mg/l (flow-through) Ecological Information This material is not expected to be harmful to aquatic life Components of this product have been identified as having potential environmental concerns Other adverse effects Ecological injuries are not known or expected under normal use 13 Disposal Considerations Disposal Instructions In accordance with local and national regulations Dispose in accordance with all applicable regulations If discarded, this product is considered a RCRA ignitable waste, D001 Dispose of this material and its container at hazardous or special waste collection point 14 Transportation Information US DOT IATA Other Information Not classified as dangerous in the meaning of transport regulations 15 Regulatory Information CERCLA/SARA Section 313 Material Ingredient(s) US Federal Regulations Relaxin-3 (h) [125I] OSHA Process Safety Standard: This material is not known to be hazardous by the OSHA Highly Hazardous Process Safety Standard, 29 CFR CERCLA/SARA - Hazardous Substances and their Reportable Quantities lb final RQ; 2270 kg final RQ CERCLA/SARA - Section Emission Reporting % de minimis concentration TSCA (Toxic Substances Control Act) - Section 12(b) - Export Notification Section 4 4 / 5

5 State Regulations This product does not contain a chemical known to the State of California to cause cancer, birth defects or other reproductive harm Massachusetts - Right To Know List 1-PROPANOL Present Present Massachusetts - Toxics Use Reduction Act CERCLA and 313 chemical International Regulations Canada - WHMIS - Ingredient Disclosure List 1-PROPANOL % (English Item 1355, French Item 187) % (English Item 12, French Item 43) 16 Other Information Disclaimer The information provided in this Material Safety Data Sheet is based on our present knowledge, and believed to be correct at the date of publication However, no representation is made concerning its accuracy and completeness It is intended as guidance only, and is not to be considered a warranty or quality specification All materials may present unknown hazards, and should be used with caution Although certain hazards are described, we cannot guarantee that these are the only hazards which exist PerkinElmer Life and Analytical Sciences shall not be held liable for any damage resulting from handling or from contact with the product 5 / 5