MATERIAL SAFETY DATA SHEET

Transcription

1 Page 1 of 8 1 CHEMICAL PRODUCT AND COMPANY INFORMATION Product Description ACETONITRILE-D3 (D, 99.8%) Cambridge Isotope Laboratories, Inc. 50 Frontage Rd ANDOVER, MA USA Web Site Phone Numbers Emergency Contact Emergency Phone Customer Service Phone Transportation cilsales@isotope.com Chemtrec (24 hours) (8:30-5:30 EST) (24 hours) 2 HAZARDS IDENTIFICATION OSHA Hazards Flammable liquid, Target Organ Effect, Harmful by ingestion. Harmful by skin absorption, Irritant. Target Organs Lungs, Blood, Kidney, Liver, Central nervous system. GHS Classification Flammable liquids (Category 2) Acute toxicity, Oral (Category 4) Acute toxicity, Inhalation (Category 4) Acute toxicity, Dermal (Category 4) Skin irritation (Category 3) Serious eye damage (Category 1) GHS Label Information Signal Word Danger Hazards Identification Flame

2 Page 2 of 8 Corrosion Exclamation mark Hazard Statement(s) Highly flammable liquid and vapour. Harmful if swallowed or in contact with skin. Causes mild skin irritation. Causes serious eye damage. Harmful if inhaled. Precautionary Statement(s) Keep away from heat/sparks/open flames/hot surfaces- No smoking. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse with water for several minutes. Remove contact lenses. HMIS Ratings Chronic Health * Physical 0 Flammability 3 Health 2 NFPA Codes Fire 3 Health 2 Reactivity 0 Potential Health Effects Eyes Ingestion Inhalation Skin Causes eye irritation. Harmful if swallowed. May be harmful if inhaled. Causes respiratory tract irritation. Harmful if absorbed through skin. Causes skin irritation. 3 COMPOSITION / INFORMATION ON INGREDIENTS Composition / Information on Ingredients Synonyms Methyl cyanide. ACN. Chemical Formula CD3CN Molecular Weight CAS No EC No Index No FIRST AID MEASURES First Aid Measures

3 Page 3 of 8 Eyes Ingestion Inhalation Skin Additional Information Flush eye with water for 15 minutes. Get medical attention. Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get immediate medical attention. Wash off with soap and plenty of water. Consult a physician. Consult a physician. Show this safety data sheet to the doctor in attendance. Move out of dangerous area. 5 FIRE FIGHTING MEASURE Fire Fighting Measures Extinguishing Media Fire Fighting Equipment Fire Fighting Procedures For small fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large fires, apply water from as far as possible. Use very large quantities (flooding) of water applied as a mist or spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Wear self contained breathing apparatus for fire fighting if necessary. Use water spray to cool unopened containers. 6 ACCIDENTAL RELEASE MEASURES Accidental Release Measures Personal Precautions Environmental Precautions Methods and materials for containment and cleanup Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations.

4 Page 4 of 8 7 HANDLING AND STORAGE Precautions for Safe Handling Handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Use explosion-proof equipment. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electrostatic charge. Conditions for Safe Storage Storage Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place. hygroscopic Handle and store under inert gas. 8 EXPOSURE CONTROL / PERSONAL PROTECTION OSHA HAZARDOUS COMPONENTS (29 CFR ) CHEMICAL NAME OSHA PEL ACGIH TLV ACETONITRILE TWA 40 ppm 20 ppm STEL 60 ppm Personal Protecton Eyes - Face Skin Respiratory Protective Clothing Work Hygienic Practices Tightly fitting safety goggles. Faceshield (8-inch minimum). Complete suit protecting against chemicals, Flame retardant antistatic protective clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. When appropriate, use NIOSH/CEN approved respirator. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. 9 PHYSICAL AND CHEMICAL PROPERTIES Physical and Chemical Properties (Unlabeled Compound) Form Color Liquid, clear Colourless

5 Page 5 of 8 Odor Pungent ph No data available. Melting Point -48 C (-54 F) Boiling Point C ( F) Flashpoint 2.0 C (35.6 F) Lower Explosion 4.4 %(V) Limit Upper Explosion 16 % (V) Limit Vapor Pressure 97.1 hpa (72.8 mmhg) at 20.0 C (68.0 F) Solubility in Water Soluble Partition Coefficient log Pow: Auto Ignition 523 C (973 F) Temperature 10 STABILITY AND REACTIVITY Stability and Reactivity Chemical Stability Possibility of Hazardous Reactions Conditions to Avoid Hazardous decomposition products Materials to avoid Stable if stored under recommended conditions. Vapors may form explosive mixture with air. Extremes of temperature and direct sunlight. Formed under fire conditions: Carbon oxides, nitrogen oxides. Acids, Bases, Oxidizing agents, Reducing agents, Alkali metals. 11 TOXICOLOGICAL INFORMATION Acute Toxicity LC50 Inhilation Rat LD50 Dermal Rabbit LD50 Oral Rat Serious Damage/Eye Irritation 8h ppm 2,000 mg/kg 2,460 mg/kg Eyes - Rabbit - Severe eye irritation.

6 Page 6 of 8 Skin Corrosion/Irritation Inhalation Respiratory or Skin Sensitization Germ Cell Mutagenicity IARC NTP OSHA Reproductive Toxicity Skin - rabbit - Mild skin irritation. Did not cause sensitization on laboratory animals. No component of this product present at levels greater than or equal to 0.1% is identifiable as probable, possible, or confirmed human carcinogen by IARC. No component of this product present at levels greater than or equal to 0.1% is identifiable as a known or anticipated carcinogen by NTP. No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Specific Target Organ Toxicity Single Exposure No data available. Repeated Exposure No data available. Other Information RTECS AL ECOLOGICAL INFORMATION Toxicity Toxicity to Fish LC50 Toxicity to Daphnia and Other Aquatic Invertebrates EC50 Persistance and Degradability Bioaccumulative Potential Mobility in Soil Pimephales promelas (fathead minnow) - 1, mg/l - 96h Daphnia magna (Water flea) - 3,600 mg/l - 48 h

7 Page 7 of 8 PBT and vpvb Assessment Other Adverse Effects 13 DISPOSAL CONSIDERATIONS Disposal Considerations Product Disposal Waste materials should be disposed of under conditions which meet Federal, State, and Local environmental control regulations. 14 TRANSPORT INFORMATION Transportation Information-DOT/IATA/IMDG UN Number 1648 Prop. Ship. Name Acetonitrile Hazard Class 3 Packing Group II Reportable Quantity 5000 lbs (RQ) DOT US Marine Pollutant No Poison Inhalation No Hazard 15 REGULATORY INFORMATION Regulatory Information Flammable liquid, Target Organ Effect, Harmful by ingestion. Harmful by skin absorption, Irritant. SARA Sara 302 Component Sara 313 Component SARA 311/312 Hazards Fire (Y/N) Acute (Y/N) No chemicals in this material are subject to the reporting requirements. Yes Y Y

8 Page 8 of 8 Chronic (Y/N) Y STATE REGULATIONS Massachusetts Right to Know Pennsylvania Right to Know New Jersey Right to Know California Proposition 65 Yes Yes Yes This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm. Canada DSL Status EU Hazard All components of this product are on the Canadian DSL list. Flammable. Harmful. Irritant. Corrosive. Safety Statements Keep away from sources of ignition - No smoking. Wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Risk Statements Highly flammable. Harmful by inhalation, in contact with skin and if swallowed. Risk of serious damage to eyes. 16 OTHER INFORMATION Additional MSDS Information This product is not radioactive. The data given for this product are those of the corresponding unlabeled compound, unless specifically indicated otherwise. Health and safety data for labeled compounds are generally not available, but are assumed to be similar or identical to the corresponding unlabeled compound. Approved On 09/10/12 Version Number 2