MATERIAL SAFETY DATA SHEET

Transcription

1 1. IDENTIFICATION CATALOG NO. Detector AP Chemiluminescent Blotting Kit , Issue Date:21 March, 2006 Revision Date: 21 January, 2004 Reagents That Contain Hazardous Materials Catalog No. Formamide Hybridization Buffer , , , CDP-Star , , Detector Block Solution 5X , Detector Block Powder See Attached Material Safety Data Sheets For Reagents Listed Above

2 1. IDENTIFICATION CATALOG NO. Formamide Hybridization Buffer , , , COMPOSITION AND INGREDIENTS INFORMATION Reagent Weight % CAS # Formamide <50% Issue Date:20 March, HAZARDS IDENTIFICATION Toxic. May cause harm to fetus. Risk of serious damage to eyes. Irritating to respiratory system and skin. Readily absorbed through skin. Target organs: blood, central nervous system. 4. FIRST-AID PROCEDURES Inhalation: Remove subject to fresh air. If not breathing, give artificial respiration. Seek medical attention if necessary. Eye and Skin Contact: Flush eyes or skin with copious amounts of water for at least 15 minutes. Discard contaminated clothing. Seek medical attention if necessary. Swallowing: If conscious, wash out mouth with water. Seek medical attention. 5. FIRE FIGHTING PROCEDURES Extinguishing Media: Foam, Alcohol Foam, CO 2, Dry Chemical and Water/Fog. Unusual Fire and Explosion Hazards: Emits toxic fumes under fire conditions. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. 6. ACCIDENTAL RELEASE MEASURES Wear self-contained breathing apparatus, rubber boots and heavy rubber gloves. Contain spill and then absorb with sand or vermiculite. Ventilate area and wash spill site after pickup. Avoid contact with skin and clothing. 7. EXPOSURE CONTROL (PERSONAL PROTECTIVE EQUIPMENT) Personal Protection: Wear MSHA/NIOSH approved respirator, chemical-resistant gloves, safety goggles and other protective clothing. Use only in a chemical fume hood, near a safety shower and eye bath. Do not breathe vapor, or get on eyes, skin or clothing. Wash thoroughly after handling. Avoid prolonged or repeated exposure 8. HANDLING AND STORAGE Store at 2-8 C. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance: Clear solution; light golden color Melting or Freezing Point: <0 C/32 F (water) Boiling Point: >100 C/212 F (water) Solubility in Water: Dilutable Flash Point (Setaflash): No flash observed 10. STABILITY AND REACTIVITY INFORMATION Stable Hazardous Decomposition Products: Carbon Monoxide, Carbon Dioxide, Nitrogen Oxides Hazardous Polymerization: Will not occur. Incompatible Materials and Conditions to Avoid: Strong oxidizing agents, acids and bases.

3 MSDS: Formamide Hybridization Buffer , , , TOXICOLOGICAL INFORMATION Acute Effects: Readily absorbed through skin. May be harmful by inhalation, ingestion or skin absorption. Causes severe eye irritation. Causes skin irritation. Material can cause severe burns and blisters which may not be immediately visible or painful. The full extent of tissue damage may not be apparent for hours. Chronic effects: May cause congenital malformation in fetus. Target organs: Blood, Central nervous system, Liver, Kidneys. To the best of our knowledge, the chemical, physical and toxicological properties of this material have not been thoroughly investigated. 12. ECOLOGICAL INFORMATION 13. DISPOSAL GUIDELINES Dissolve or mix with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all Federal, State and Local laws concerning health and pollution. 14. TRANSPORT INFORMATION Does not meet the definition of a hazardous material for US DOT transportation purposes. 15. REGULATORY INFORMATION AND CONSIDERATIONS This product is a mixture that may contain one or more hazardous chemicals. The hazardous ingredients listed are only those as required by 29 CFR g 2.C1 16. OTHER The above information is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. KPL shall not be held liable for any damage resulting from handling or from contact with the above product. Users should make their own investigations to determine the suitability of the information for their particular purposes.

4 1. IDENTIFICATION Catalog No. CDP-Star , , , COMPOSITION AND INGREDIENTS INFORMATION Reagent Weight % CAS Disodium 2-chloro-5-(4-methoxyspiro (1,2-dioxetane-3,2 -(5 -chloro)-tricyclo ( ,7 )decan)-4-yl)-1-phenyl phosphate <2% Tropix Buffer (amino alcohol) <3% Issue Date:20 March, HAZARDS IDENTIFICATION The toxicological properties of CDP-Star have not been investigated. All materials and mixtures may present unknown hazards and should be used by workers technically qualified to handle potentially hazardous chemicals. The buffering components are known to be caustic and an irritant to the upper respiratory tract upon prolonged inhalation. 4. FIRST-AID PROCEDURES Inhalation: Remove subject to fresh air. Seek medical attention if necessary. Eye and Skin Contact: Flush eyes or skin with copious amounts of water. Discard contaminated clothing. Seek medical attention. Swallowing: If conscious, wash out mouth with water. Seek medical attention. 5. FIRE FIGHTING PROCEDURES Extinguishing Media: Foam, Alcohol Foam, CO 2, Dry Chemical and Water/Fog. Unusual Fire and Explosion Hazards: Upon evaporation of water, may omit toxic fumes under fire conditions. Wear self contained breathing apparatus and protective clothing to prevent contact with skin and eyes. 6. ACCIDENTAL RELEASE MEASURES Contain spill and then absorb with an inert cellulosic material such as absorbent paper. Evaporate the water and transfer impregnated material to a suitable container for disposal. Avoid contact with skin and clothing. 7. EXPOSURE CONTROL (PERSONAL PROTECTIVE EQUIPMENT) Personal Protection: Wear impervious gloves, safety glasses or goggles and lab coat or other protective clothing. Handle near a safety shower and eyewash station. 8. HANDLING AND STORAGE Store at 2-8 C. Protect from light and heat. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance: Clear solution Melting or Freezing Point: <0 C/32 F (water) Boiling Point: 100 C/212 F (water) Solubility in Water: Dilutable 10. STABILITY AND REACTIVITY INFORMATION Stable Hazardous Decomposition Products: Carbon Monoxide, Carbon Dioxide, Phosphorus oxides, Phosphines, Hydrogen chloride Hazardous Polymerization: Will not occur. Incompatibility Materials to Avoid: Strong oxidizing or reducing agents, acids, combustible materials.

5 MSDS: CDP-Star , , , TOXICOLOGICAL INFORMATION The toxicological properties of CDP-Star have not been investigated. All materials and mixtures may present unknown hazards and should be used by workers technically qualified to handle potentially hazardous chemicals. The buffering components are known to be caustic and an irritant to the upper respiratory tract upon prolonged inhalation. 12. ECOLOGICAL INFORMATION 13. DISPOSAL GUIDELINES Burn in a chemical incinerator with an afterburner and scrubber. Observe all Federal, State and Local laws concerning health and pollution. 14. TRANSPORT INFORMATION 15. REGULATORY INFORMATION AND CONSIDERATIONS This product is a mixture that may contain one or more hazardous chemicals. The hazardous ingredients listed are only those as required by 29 CFR g 2.C1 16. OTHER The above information is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. KPL shall not be held liable for any damage resulting from handling or from contact with the above product. Users should make their own investigations to determine the suitability of the information for their particular purposes.

6 1. IDENTIFICATION CATALOG NO. Detector Block Solution 5X , COMPOSITION AND INGREDIENTS INFORMATION Reagent Weight % CAS # 1 M Tris HCl, ph % HAZARDS IDENTIFICATION Inhalation: Irritating to mucus membranes and upper respiratory tract. Eye and Skin: Causes eye irritation. Prolonged contact can cause skin irritation. 4. FIRST-AID PROCEDURES Inhalation: Remove subject to fresh air. If not breathing, give artificial respiration. If breathing is labored, give oxygen. Seek medical attention. Eye and Skin Contact: Flush eyes with copious amounts of water for at least 15 minutes. In case of skin contact, flush the area with copious amounts of water. Wash contaminated clothing before reuse. Seek medical attention if necessary. 5. FIRE FIGHTING PROCEDURES Extinguishing Media: Use extinguishing media appropriate to surrounding fire conditions. Use Water Spray, Carbon Dioxide, Dry Chemical Powder or Appropriate Foam. Unusual Fire and Explosion Hazards: May emit toxic fumes under fire conditions. Wear self-contained breathing apparatus and appropriate clothing to prevent contact with skin and eyes. 6. ACCIDENTAL RELEASE MEASURES If spilled, first contain the spill. Wear chemical safety goggles, rubber boots, heavy gloves and other appropriate protective apparel. Clean up the spill with absorbent material and place in closed containers for disposal. Wash the spill site thoroughly. Ventilate area before returning to the spill site. 7. EXPOSURE CONTROL (PERSONAL PROTECTIVE EQUIPMENT) Inhalation: May be harmful if inhaled in large quantities. Use in a well ventilated area with caution. Eye Contact: Direct contact will result in irritation. Wear chemical safety eyewear for eye protection. Skin Contact: Prolonged and repeated contact with product may cause irritation. Wear rubber gloves when handling this material. Respiratory Protection: None required if good ventilation is maintained. Otherwise wear an MSHA/NIOSH approved respirator for your protection. 8. HANDLING AND STORAGE Store at 2-8 C. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance: Clear, brownish solution. Solubility in Water: Dilutable 10. STABILITY AND REACTIVITY INFORMATION Stable under ordinary use and storage.

7 MSDS: Detector Block Solution (5X) , TOXICOLOGICAL INFORMATION Hazardous Polymerization: Will not occur. Incompatibility Materials to Avoid: Incompatible with bases and strong oxidizing agents. Hazardous Combustion or Decomposition Products: Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides. 12. ECOLOGICAL INFORMATION No information found. 13. DISPOSAL GUIDELINES Observe all Federal, State and Local laws concerning health and pollution. 14. TRANSPORT INFORMATION 15. REGULATORY INFORMATION AND CONSIDERATIONS This product is a mixture that may contain one or more hazardous chemicals. The hazardous ingredients listed are only those as required by 29 CFR g 2.C1 16. OTHER The above information is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. KPL shall not be held liable for any damage resulting from handling or from contact with the above product. Users should make their own investigations to determine the suitability of the information for their particular purposes.

8 Issue Date:23 March, 2006 Revision Date: 5 February, IDENTIFICATION Catalog No Detector Block Powder COMPOSITION AND INGREDIENTS INFORMATION Reagent Weight % CAS # Proprietary Component 100% Proprietary (Trade Secret per 29 CFR i 1) 3. HAZARDS IDENTIFICATION Eye: Dust can be mildly irritating. Skin: Inhalation: Ingestion: 4. FIRST-AID PROCEDURES Unlikely to be necessary. Eye and Skin Contact: Flush eyes with water and wash skin with soap and water. Inhalation: Ingestion: 5. FIRE FIGHTING PROCEDURES Flashpoint: 550 F Extinguishing Media: Water Spray, CO 2, Dry Chemicals Special Firefighting Procedures: At high temperatures (+750 ) in a building fire, there will be considerable smoke before and after combustion in which case, smoke inhalation protection should be used. Unusual Fire and Explosion Hazards: At high temperatures (+750 ) in a building fire, there will be considerable smoke before and after combustion in which case, smoke inhalation protection should be used. 6. ACCIDENTAL RELEASE MEASURES Scoop up powder into suitable container. 7. EXPOSURE CONTROL (PERSONAL PROTECTIVE EQUIPMENT) Eye Contact: Goggles may be used when dumping bags. Inhalation: Local exhaust desirable when dumping bags. Skin Contact: Protective gloves, clothing or other equipment in accordance with current GMP standards. Respiratory Protection: Dust respirator 3M Part no: 8800 or other NIOSH approved version. Work/Hygenic Practices: In accordance with current GMP standards. 8. HANDLING AND STORAGE Avoid overexposure to excessive dust particles. Store away from heat and water sources. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance: Cream color, granular powder, slight chessy odor Melting or Freezing Point: Boiling Point: Solubility in Water: Colloidally dispersible Specific Gravity (H 2 O = 1): 1.28

9 MSDS: Detector Block Powder STABILITY AND REACTIVITY INFORMATION Stability: Stable Conditions to Avoid: Practices which produce dust. Incompatibilities: None. Hazardous Combustion or Decomposition Products: None. Hazardous Polymerization: Will Not Occur 11. TOXICOLOGICAL INFORMATION Acute Effects: Eyes: dust can be mildly irritating. 12. ECOLOGICAL INFORMATION 13. DISPOSAL GUIDELINES As a food product and in accordance with local, state and federal regulations covering solid waste disposal. 14. TRANSPORT INFORMATION Not regulated. 15. REGULATORY INFORMATION AND CONSIDERATIONS 16. OTHER The above information is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. KPL shall not be held liable for any damage resulting from handling or from contact with the above product. Users should make their own investigations to determine the suitability of the information for their particular purposes.