Safety Data Sheet Vitamin D3 1.0 Mio IU/G in Corn Oil Revision date : 2017/02/16 Page: 1/10

Transcription

1 Revision date : 2017/02/16 Page: 1/10 1. Identification Product identifier used on the label Recommended use of the chemical and restriction on use Recommended use*: food additive(s); Vitamin * The Recommended use identified for this product is provided solely to comply with a Federal requirement and is not part of the seller's published specification. The terms of this Safety Data Sheet (SDS) do not create or infer any warranty, express or implied, including by incorporation into or reference in the seller's sales agreement. Details of the supplier of the safety data sheet Company: BASF CORPORATION 100 Park Avenue Florham Park, NJ 07932, USA Telephone: Emergency telephone number CHEMTREC: BASF HOTLINE: HELP (4357) Other means of identification Synonyms: cholecalciferol 2. Hazards Identification According to Regulation 2012 OSHA Hazard Communication Standard; 29 CFR Part Classification of the product Acute Tox. 4 (oral) Acute toxicity Acute Tox. 4 (dermal) Acute toxicity STOT RE 1 Specific target organ toxicity repeated exposure Label elements Pictogram:

2 Revision date : 2017/02/16 Page: 2/10 Signal Word: Danger Hazard Statement: H312 H302 H372 Harmful in contact with skin. Harmful if swallowed. Causes damage to organs through prolonged or repeated exposure. Precautionary Statements (Prevention): P280 Wear protective gloves/clothing. P260 Do not breathe dust/gas/mist/vapours. P270 Do not eat, drink or smoke when using this product. P264 Wash with plenty of water and soap thoroughly after handling. Precautionary Statements (Response): P311 Call a POISON CENTER or doctor/physician. P303 + P352 IF ON SKIN (or hair): Wash with plenty of soap and water. P361 Take off immediately all contaminated clothing. P301 + P330 IF SWALLOWED: rinse mouth. Precautionary Statements (Disposal): P501 Dispose of contents/container to hazardous or special waste collection point. Hazards not otherwise classified If applicable information is provided in this section on other hazards which do not result in classification but which may contribute to the overall hazards of the substance or mixture. High risk of slipping due to leakage/spillage of product. Labeling of special preparations (GHS): The following percentage of the mixture consists of components(s) with unknown hazards regarding the acute toxicity: 98 % 3. Composition / Information on Ingredients According to Regulation 2012 OSHA Hazard Communication Standard; 29 CFR Part CAS Number Weight % Chemical name % Corn oil % Vitamin D3 4. First-Aid Measures Description of first aid measures General advice: Remove contaminated clothing.

3 Revision date : 2017/02/16 Page: 3/10 If inhaled: Keep patient calm, remove to fresh air, seek medical attention. If on skin: Wash thoroughly with soap and water. If irritation develops, seek medical attention. If in eyes: Wash affected eyes for at least 15 minutes under running water with eyelids held open. If irritation develops, seek medical attention. If swallowed: Rinse mouth and then drink plenty of water. Seek medical attention. Most important symptoms and effects, both acute and delayed Symptoms: The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11., Further important symptoms and effects are so far not known. Hazards: No applicable information available. Indication of any immediate medical attention and special treatment needed Note to physician Treatment: Symptomatic treatment (decontamination, vital functions). 5. Fire-Fighting Measures Extinguishing media Suitable extinguishing media: water spray, carbon dioxide, dry powder, foam Special hazards arising from the substance or mixture Hazards during fire-fighting: carbon monoxide, carbon dioxide, 2-propenal, harmful vapours The substances/groups of substances mentioned can be released in case of fire. Burning produces harmful and toxic fumes. Advice for fire-fighters Protective equipment for fire-fighting: Firefighters should be equipped with self-contained breathing apparatus and turn-out gear. Further information: Dispose of fire debris and contaminated extinguishing water in accordance with official regulations. 6. Accidental release measures Further accidental release measures: High risk of slipping due to leakage/spillage of product. Personal precautions, protective equipment and emergency procedures

4 Revision date : 2017/02/16 Page: 4/10 Ensure adequate ventilation. Spilled material may cause slippery floors. Avoid contact with the skin, eyes and clothing. Environmental precautions Do not discharge into drains/surface waters/groundwater. Methods and material for containment and cleaning up For large amounts: Dike spillage. Pump off product. For residues: Contain with absorbent material (e.g. sand, silica gel, acid binder, general purpose binder, sawdust). Dispose of absorbed material in accordance with regulations. 7. Handling and Storage Precautions for safe handling Ensure thorough ventilation of stores and work areas. Wear suitable protective clothing and gloves. Avoid contact with the skin, eyes and clothing. Keep container tightly sealed. Protection against fire and explosion: Prevent electrostatic charge - sources of ignition should be kept well clear - fire extinguishers should be kept handy. Conditions for safe storage, including any incompatibilities No applicable information available. Further information on storage conditions: Protect from the effects of light. Keep container tightly closed and dry; store in a cool place. Protect from air. 8. Exposure Controls/Personal Protection Components with occupational exposure limits Corn oil OSHA PEL PEL 5 mg/m3 Respirable fraction ; PEL 15 mg/m3 Total dust ; TWA value 15 mg/m3 Total dust ; TWA value 5 mg/m3 Respirable fraction ; Advice on system design: Ensure adequate ventilation. Local exhaust ventilation preferred. Personal protective equipment Respiratory protection: Wear respiratory protection if ventilation is inadequate. Wear a NIOSH-certified (or equivalent) organic vapour/particulate respirator. Suitable respiratory protection for higher concentrations or long-term effect: Hand protection: Chemical resistant protective gloves, Suitable materials, plastic, rubber Eye protection: Safety glasses with side-shields.

5 Revision date : 2017/02/16 Page: 5/10 Body protection: Body protection must be chosen depending on activity and possible exposure, e.g. head protection, apron, protective boots, chemical-protection suit. General safety and hygiene measures: Handle in accordance with good industrial hygiene and safety practice. Avoid contact with the skin, eyes and clothing. Do not breathe vapour/spray. No eating, drinking, smoking or tobacco use at the place of work. Hands and/or face should be washed before breaks and at the end of the shift. Store work clothing separately. 9. Physical and Chemical Properties Form: oily Odour: odourless Odour threshold: not applicable, odour not perceivable Colour: white to slightly yellow ph value: insoluble Melting point: approx. -14 C Boiling point: The substance / product decomposes therefore not determined. Sublimation point: No applicable information available. Flash point: C (DIN 51584) Flammability: not highly flammable Lower explosion limit: For liquids not relevant for classification and labelling. Upper explosion limit: For liquids not relevant for classification and labelling. Autoignition: approx. 330 C Vapour pressure: The product has not been tested. Vapour density: No applicable information available. Partitioning coefficient n- not applicable for mixtures octanol/water (log Pow): Thermal decomposition: No applicable information available. Viscosity, dynamic: approx mpa.s (ASTM D ) ( 24 C) Viscosity, kinematic: No applicable information available. Solubility in water: ( C) emulsifiable Solubility (quantitative): No applicable information available. Solubility (qualitative): No applicable information available. Evaporation rate: No applicable information available. Other Information: If necessary, information on other physical and chemical parameters is indicated in this section. 10. Stability and Reactivity Reactivity No hazardous reactions if stored and handled as prescribed/indicated. Corrosion to metals: No data available. Oxidizing properties: not fire-propagating

6 Revision date : 2017/02/16 Page: 6/10 Chemical stability The product is stable if stored and handled as prescribed/indicated. Possibility of hazardous reactions No hazardous reactions if stored and handled as prescribed/indicated. Conditions to avoid Avoid all sources of ignition: heat, sparks, open flame. See MSDS section 7 - Handling and storage. Incompatible materials azides, oxidizing agents Hazardous decomposition products Decomposition products: Hazardous decomposition products: No hazardous decomposition products if stored and handled as prescribed/indicated. Thermal decomposition: No applicable information available. 11. Toxicological information Primary routes of exposure Routes of entry for solids and liquids are ingestion and inhalation, but may include eye or skin contact. Routes of entry for gases include inhalation and eye contact. Skin contact may be a route of entry for liquefied gases. Acute Toxicity/Effects Acute toxicity Assessment of acute toxicity: Of moderate toxicity after single ingestion. Of low toxicity after shortterm skin contact. Oral Type of value: LD50 Species: rat Value: mg/kg Literature data. Inhalation Type of value: LC50 Species: rat Value: approx mg/l Exposure time: 4 h Tested as dust aerosol. Literature data. The EU classification 'very toxic by inhalation' obtained from examination with inhalable aerosol.

7 Revision date : 2017/02/16 Page: 7/10 Dermal Type of value: LD50 Species: rat Value: mg/kg Literature data. Irritation / corrosion Assessment of irritating effects: May cause slight irritation to the eyes. May cause slight irritation to the skin. Sensitization Assessment of sensitization: Based on available Data, the classification criteria are not met. Aspiration Hazard No aspiration hazard expected. Chronic Toxicity/Effects Repeated dose toxicity Assessment of repeated dose toxicity: Repeated oral exposure to small quantities may affect certain organs. The substance may cause damage to the kidney even after repeated ingestion of low doses, as shown in animal studies. The substance may cause damage to blood vessels even after repeated ingestion of low doses, as shown in animal studies. Genetic toxicity Assessment of mutagenicity: No mutagenic effect was found in various tests with bacteria, microorganims and mammalian cell culture. Literature data. Information on: D,L-alpha-Tocopherol Assessment of mutagenicity: Results from a number of mutagenicity studies with microorganisms, mammalian cell culture and mammals are available. Taking into account all of the information, there is no indication that the substance is mutagenic. Carcinogenicity Information on: D,L-alpha-Tocopherol Assessment of carcinogenicity: In long-term studies in rats in which the substance was given by feed, a carcinogenic effect was not observed. The product has not been tested. The statement has been derived from substances/products of a similar structure or composition. Reproductive toxicity Assessment of reproduction toxicity: After the uptake of low doses an impairment of fertility will not be expected in humans. Symptoms of Exposure

8 Revision date : 2017/02/16 Page: 8/10 The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11., Further important symptoms and effects are so far not known. 12. Ecological Information Toxicity Aquatic toxicity Assessment of aquatic toxicity: There is a high probability that the product is not acutely harmful to aquatic organisms. The product has not been tested. The statement has been derived from the properties of the individual components. Toxicity to fish LC50 (96 h) > 10,000 mg/l, Leuciscus idus (DIN Part 15, static) The product has low solubility in the test medium. An aqueous dispersion has been tested. Tested above maximum solubility. The details of the toxic effect relate to the nominal concentration. Aquatic invertebrates EC50 (48 h) > 100 mg/l, Daphnia magna (OECD Guideline 202, part 1, static) The product has low solubility in the test medium. An eluate has been tested. The details of the toxic effect relate to the nominal concentration. No toxic effects occur within the range of solubility. Aquatic plants EC50 (96 h) > 0.17 mg/l (growth rate), Selenastrum capricornutum (OECD Guideline 201, static) The product has low solubility in the test medium. An eluate has been tested. No toxic effects occur within the range of solubility. The statement of the toxic effect relates to the analytically determined concentration. No observed effect concentration (96 h) 0.17 mg/l (growth rate), Pseudokirchneriella subcapitata (OECD Guideline 201, static) The statement of the toxic effect relates to the analytically determined concentration. The product has low solubility in the test medium. An eluate has been tested. No toxic effects occur within the range of solubility. Microorganisms/Effect on activated sludge Toxicity to microorganisms OECD Guideline 209 aerobic activated sludge, domestic/ec20 (0.5 h): > 1,000 mg/l Persistence and degradability Assessment biodegradation and elimination (H2O)

9 Revision date : 2017/02/16 Page: 9/10 The product is virtually insoluble in water and can thus be separated from water mechanically in suitable effluent treatment plants. Bioaccumulative potential Assessment bioaccumulation potential Discharge into the environment must be avoided. Mobility in soil Assessment transport between environmental compartments No data available. 13. Disposal considerations Waste disposal of substance: Observe national and local legal requirements. Container disposal: Dispose of in accordance with national, state and local regulations. 14. Transport Information Land transport USDOT Not classified as a dangerous good under transport regulations Sea transport IMDG Not classified as a dangerous good under transport regulations Air transport IATA/ICAO Not classified as a dangerous good under transport regulations 15. Regulatory Information Federal Regulations Registration status: Chemical TSCA, US released / listed Food TSCA, US released / exempt EPCRA 311/312 (Hazard categories): Acute; Chronic State regulations State RTK CAS Number Chemical name PA Corn oil

10 Revision date : 2017/02/16 Page: 10/10 NFPA Hazard codes: Health : 1 Fire: 1 Reactivity: 0 Special: HMIS III rating Health: 1 Flammability: 1 Physical hazard: Other Information SDS Prepared by: BASF NA Product Regulations SDS Prepared on: 2017/02/16 We support worldwide Responsible Care initiatives. We value the health and safety of our employees, customers, suppliers and neighbors, and the protection of the environment. Our commitment to Responsible Care is integral to conducting our business and operating our facilities in a safe and environmentally responsible fashion, supporting our customers and suppliers in ensuring the safe and environmentally sound handling of our products, and minimizing the impact of our operations on society and the environment during production, storage, transport, use and disposal of our products. IMPORTANT: WHILE THE DESCRIPTIONS, DESIGNS, DATA AND INFORMATION CONTAINED HEREIN ARE PRESENTED IN GOOD FAITH AND BELIEVED TO BE ACCURATE, IT IS PROVIDED FOR YOUR GUIDANCE ONLY. BECAUSE MANY FACTORS MAY AFFECT PROCESSING OR APPLICATION/USE, WE RECOMMEND THAT YOU MAKE TESTS TO DETERMINE THE SUITABILITY OF A PRODUCT FOR YOUR PARTICULAR PURPOSE PRIOR TO USE. NO WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, ARE MADE REGARDING PRODUCTS DESCRIBED OR DESIGNS, DATA OR INFORMATION SET FORTH, OR THAT THE PRODUCTS, DESIGNS, DATA OR INFORMATION MAY BE USED WITHOUT INFRINGING THE INTELLECTUAL PROPERTY RIGHTS OF OTHERS. IN NO CASE SHALL THE DESCRIPTIONS, INFORMATION, DATA OR DESIGNS PROVIDED BE CONSIDERED A PART OF OUR TERMS AND CONDITIONS OF SALE. FURTHER, YOU EXPRESSLY UNDERSTAND AND AGREE THAT THE DESCRIPTIONS, DESIGNS, DATA, AND INFORMATION FURNISHED BY OUR COMPANY HEREUNDER ARE GIVEN GRATIS AND WE ASSUME NO OBLIGATION OR LIABILITY FOR THE DESCRIPTION, DESIGNS, DATA AND INFORMATION GIVEN OR RESULTS OBTAINED, ALL SUCH BEING GIVEN AND ACCEPTED AT YOUR RISK. END OF DATA SHEET