MSDS# Section 1 - Chemical Product and Company Identification MSDS Name: Buffer Concentrate ph 10.00

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1 Material Safety Data Sheet Buffer Concentrate ph 1000 MSDS# Section 1 - Chemical Product and Company Identification MSDS Name: Buffer Concentrate ph 1000 Catalog Numbers: NC , SB Synonyms: None Fisher Scientific Company Identification: One Reagent Lane Fair Lawn, NJ For information in the US, call: Emergency Number US: CHEMTREC Phone Number, US: CAS#: Disodium EDTA %: 09 EINECS#: CAS#: Sodium hydroxide %: 17 EINECS#: C CAS#: Potassium chloride %: 40 EINECS#: CAS#: Water %: 900 EINECS#: Section 2 - Composition, Information on Ingredients

2 CAS#: Boric acid %: 30 EINECS#: Text for R-phrases: see Section 16 None listed None listed Section 3 - Hazards Identification EMERGENCY OVERVIEW Caution! This is expected to be a low hazard for usual industrial handling May cause eye, skin, and respiratory tract irritation Target Organs: None Potential Health Effects Eye: Skin: Ingestion: Inhalation: Chronic: Eyes: Skin: Ingestion: Inhalation: Notes to Physician: General Information: May cause eye irritation May cause mild skin irritation Low hazard for usual industrial handling May cause gastric disturbances and electrolytic imbalance May cause respiratory tract irritation Low hazard for usual industrial handling No information found Section 4 - First Aid Measures Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids If irritation develops, get medical aid Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes Get medical aid if irritation develops or persists Wash clothing before reuse Do not induce vomiting If victim is conscious and alert, give 2-4 cupfuls of milk or water Never give anything by mouth to an unconscious person Get medical aid if irritation or symptoms occur Remove from exposure and move to fresh air immediately If not breathing, give artificial respiration If breathing is difficult, give oxygen Get medical aid if cough or other symptoms appear Section 5 - Fire Fighting Measures As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes Extinguishing Substance is noncombustible; use agent most appropriate to extinguish surrounding fire Media: Autoignition Not applicable Temperature: Flash Point: Not applicable Explosion Limits: Lower: Explosion Limits: Upper: NFPA Rating: health: 1; flammability: 0; instability: 0; General Information: Section 6 - Accidental Release Measures Use proper personal protective equipment as indicated in Section 8 Absorb spill with inert material (eg vermiculite, sand or earth), then place in suitable container Avoid

3 Spills/Leaks: runoff into storm sewers and ditches which lead to waterways Clean up spills immediately, observing precautions in the Protective Equipment section Provide ventilation Section 7 - Handling and Storage Wash thoroughly after handling Use with adequate ventilation Avoid contact with eyes, skin, and clothing Keep Handling: container tightly closed Avoid ingestion and inhalation Storage: Store in a cool, dry, well-ventilated area away from incompatible substances Keep containers tightly closed Section 8 - Exposure Controls, Personal Protection Chemical Name ACGIH NIOSH OSHA - Final PELs Disodium EDTA none listed none listed none listed Sodium hydroxide 2 mg/m3 Ceiling 10 mg/m3 IDLH 2 mg/m3 TWA Potassium chloride none listed none listed none listed Water none listed none listed none listed Boric acid 2 mg/m3 none listed none listed (inhalable fraction, listed under Borate compounds, inorganic); 6 mg/m3 STEL (inhalable fraction, listed under Borate compounds, inorganic) OSHA Vacated PELs: Disodium EDTA: None listed Sodium hydroxide: None listed Potassium chloride: None listed Water: None listed Boric acid: None listed Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower Use adequate ventilation to keep airborne concentrations low Exposure Limits Personal Protective Equipment Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face Eyes: protection regulations in 29 CFR or European Standard EN166 Skin: Wear appropriate protective gloves to prevent skin exposure Clothing: Wear appropriate protective clothing to prevent skin exposure Follow the OSHA respirator regulations found in 29 CFR or European Standard EN 149 Use a Respirators: NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced Section 9 - Physical and Chemical Properties Physical State: Liquid Color: clear colorless Odor: none reported ph: 100 Vapor Pressure: Vapor Density: Evaporation Rate: Viscosity: Boiling Point: Freezing/Melting Point:

4 Chemical Stability: Conditions to Avoid: Incompatibilities with Other Materials Hazardous Decomposition Products Hazardous Polymerization RTECS#: LD50/LC50: Carcinogenicity: Other: Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: Mixture Molecular Weight: Not applicable Section 10 - Stability and Reactivity Stable under normal temperatures and pressures None reported None Has not been reported Section 11 - Toxicological Information CAS# : AH CAS# : WB CAS# : TS CAS# : ZC CAS# : ED ED CAS# : Oral, mouse: LD50 = 2050 mg/kg; Oral, rabbit: LD50 = 2300 mg/kg; Oral, rat: LD50 = 2 gm/kg; CAS# : Draize test, rabbit, eye: 400 ug Mild; Draize test, rabbit, eye: 1% Severe; Draize test, rabbit, eye: 50 ug/24h Severe; Draize test, rabbit, eye: 1 mg/24h Severe; Draize test, rabbit, skin: 500 mg/24h Severe; CAS# : Draize test, rabbit, eye: 500 mg/24h Mild; Oral, mouse: LD50 = 1500 mg/kg; Oral, rat: LD50 = 2600 mg/kg; CAS# : Oral, rat: LD50 = >90 ml/kg; CAS# : Oral, mouse: LD50 = 3450 mg/kg; Oral, rat: LD50 = 2660 mg/kg; Oral, rat: LD50 = 2500 mg/kg; Disodium EDTA - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65 Sodium hydroxide - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65 Potassium chloride - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65 Water - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65 Boric acid - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65 See actual entry in RTECS for complete information Section 12 - Ecological Information Section 13 - Disposal Considerations Dispose of in a manner consistent with federal, state, and local regulations US DOT Section 14 - Transport Information

5 Shipping Name: Not regulated as a hazardous material Hazard Class: UN Number: Packing Group: Canada TDG Shipping Name: Hazard Class: UN Number: Packing Group: USA RQ: CAS# : 1000 lb final RQ; 454 kg final RQ European/International Regulations US Federal TSCA European Labeling in Accordance with EC Directives Safety Phrases: S 24/25 Avoid contact with skin and eyes WGK (Water Danger/Protection) Canada CAS# : 2 CAS# : 1 CAS# : 1 CAS# : CAS# : 1 Section 15 - Regulatory Information CAS# is listed on Canada's DSL List CAS# is listed on Canada's DSL List CAS# is listed on Canada's DSL List CAS# is listed on Canada's DSL List CAS# is listed on Canada's DSL List Canadian WHMIS Classifications: This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations CAS# is not listed on Canada's Ingredient Disclosure List CAS# is listed on Canada's Ingredient Disclosure List CAS# is not listed on Canada's Ingredient Disclosure List CAS# is not listed on Canada's Ingredient Disclosure List CAS# is listed on Canada's Ingredient Disclosure List CAS# is listed on the TSCA Inventory CAS# is listed on the TSCA Inventory CAS# is listed on the TSCA Inventory CAS# is listed on the TSCA Inventory CAS# is listed on the TSCA

6 Inventory Section 16 - Other Information MSDS Creation Date: 3/05/1999 Revision #6 Date 7/20/2009 The information above is believed to be accurate and represents the best information currently available to us However, we make no warranty of merchantibility or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use Users should make their own investigations to determine the suitability of the information for their particular purposes In no event shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential, or exemplary damages howsoever arising, even if the company has been advised of the possibility of such damages

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