: Bst DNA Polymerase, Exo-

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1 Revision date: 02/10/2016 Version: 1.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product name Product form : Bst DNA Polymerase, Exo- : Mixture Product code : , , Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture 1.3. Details of the supplier of the safety data sheet Lucigen Corporation 2905 Parmenter Street Middleton, WI U.S.A. Phone: (608) Fax: (608) techserv@lucigen.com : Laboratory Reagents For in vitro Research Use Only 1.4. Emergency telephone number Emergency number : (Lucigen: Monday-Friday, 8:00AM-5:00PM) SECTION 2: Hazards identification 2.1. Classification of the substance or mixture GHS-US classification Not classified 2.2. Label elements GHS-US labelling No labelling applicable 2.3. Other hazards 2.4. Unknown acute toxicity (GHS-US) No data available SECTION 3: Composition/information on ingredients 3.1. Substance Glycerol in aqueous solution Mixture Name Product identifier % Glycerol, CAS# Contains no other hazardous ingredients at levels requiring disclosure by the OSHA Hazard Communication Standard (29 CFR ). SECTION 4: First aid measures Ingredient in 1 component: Description of first aid measures First-aid measures general First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact First-aid measures after ingestion : If exposed or concerned, get medical attention/advice. Show this safety data sheet to the doctor in attendance. Wash contaminated clothing before re-use. Never give anything to an unconscious person. : IF INHALED: Remove to fresh air and keep at rest in a comfortable position for breathing. : IF ON SKIN (or clothing): Remove affected clothing and wash all exposed skin with water for at least 15 minutes. : IF IN EYES: Immediately flush with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do so. Continue rinsing. : IF SWALLOWED: rinse mouth thoroughly. Do not induce vomiting without advice from poison control center or medical professional. Get medical attention if you feel unwell Most important symptoms and effects, both acute and delayed Symptoms/injuries : Not expected to present a significant acute hazard under anticipated conditions of normal use. Symptoms/injuries after inhalation : May cause upper respiratory irratation. Symptoms/injuries after skin contact : May cause skin irritation. 02/10/2016 Bst DNA Polymerase, Exo- Page 1

2 Symptoms/injuries after eye contact Symptoms/injuries after ingestion : Direct contact with the eyes is likely to be irritating. : May cause gastrointestinal irritation Indication of any immediate medical attention and special treatment needed SECTION 5: Firefighting measures 5.1. Extinguishing media Suitable extinguishing media : Dry powder. Foam. Sand. Water spray. Carbon dioxide Special hazards arising from the substance or mixture Fire hazard : Product is not flammable. Explosion hazard : Product is not explosive. Reactivity : No dangerous reactions known under normal conditions of use Advice for firefighters Firefighting instructions Protection during firefighting : Use water spray or fog for cooling exposed containers. Exercise caution when fighting any chemical fire. Do not dispose of fire-fighting water in the environment. : Do not enter fire area without proper protective equipment, including respiratory protection. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures General measures For non-emergency personnel : Ventilate area. Evacuate area. Keep upwind. Spill should be handled by trained clean-up crews properly equipped with respiratory equipment and full chemical protective gear (see Section 8). Protective equipment : Wear Protective equipment as described in Section For emergency responders Protective equipment : Wear suitable protective clothing, gloves and eye or face protection. For further information refer to section 8: "Exposure controls/personal protection" Environmental precautions Prevent entry to sewers and public waters. Notify authorities if liquid enters sewers or public waters. Avoid release to the environment Methods and material for containment and cleaning up For containment Methods for cleaning up 6.4. Reference to other sections SECTION 7: Handling and storage : Contain any spills with dikes or absorbents to prevent migration and entry into sewers or streams. : Soak up spills with inert solids, such as clay or diatomaceous earth as soon as possible. This material and its container must be disposed of in a safe way, and as per local legislation Precautions for safe handling Precautions for safe handling : Do not handle until all safety precautions have been read and understood. Wear recommended personal protective equipment. Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work. Keep away from sources of ignition - No smoking Conditions for safe storage, including any incompatibilities Storage conditions : Store in a well-ventilated place. Keep container tightly closed. SECTION 8: Exposure controls/personal protection 8.1. Control parameters 8.2. Exposure controls Appropriate engineering controls Personal protective equipment : Provide adequate general and local exhaust ventilation. Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Use explosion-proof equipment with flammable materials. Ensure adequate ventilation, especially in confined areas. : Gloves. Protective goggles. 02/10/2016 Bst DNA Polymerase, Exo- 2/5

3 Hand protection Eye protection Skin and body protection Respiratory protection : Use gloves chemically resistant to this material when prolonged or repeated contact could occur. Gloves should be classified under Standard EN 374 or ASTM F1296. Suitable gloves for this specific application can be recommended by the glove supplier. Suggested glove materials are: Neoprene, Nitrile/butadiene rubber, Polyethylene, Ethyl vinyl alcohol laminate, PVC or vinyl. : Use eye protection suitable to the environment. Avoid direct contact with eyes. : Wear long sleeves, and chemically impervious PPE/coveralls to minimize bodily exposure. : Use NIOSH-approved dust/particulate respirator. Where vapor, mist, or dust exceed PELs or other applicable OELs, use NIOSH-approved respiratory protective equipment. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state : Liquid Color Odor Odor Threshold ph Relative evaporation rate (butylacetate=1) Melting point Freezing point Boiling point Flash point Auto-ignition temperature Decomposition temperature Flammability (solid, gas) Vapour pressure Relative vapour density at 20 C Relative density Solubility Log Pow Log Kow Viscosity, kinematic Viscosity, dynamic Explosive properties Oxidising properties Explosive limits 9.2. Other information SECTION 10: Stability and reactivity Reactivity No dangerous reactions known under normal conditions of use Chemical stability Stable under use and storage conditions as recommended in section Possibility of hazardous reactions Conditions to avoid Incompatible materials Hazardous decomposition products SECTION 11: Toxicological information Information on toxicological effects Acute toxicity 02/10/2016 Bst DNA Polymerase, Exo- 3/5

4 Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitisation Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity (single exposure) Specific target organ toxicity (repeated exposure) Aspiration hazard Symptoms/injuries after inhalation Symptoms/injuries after skin contact Symptoms/injuries after eye contact Symptoms/injuries after ingestion : May cause upper respiratory irratation. : May cause skin irritation. : Direct contact with the eyes is likely to be irritating. : May cause gastrointestinal irritation. SECTION 12: Ecological information Toxicity Persistence and degradability Bioaccumulative potential Mobility in soil Other adverse effects SECTION 13: Disposal considerations Waste treatment methods Waste treatment methods Waste disposal recommendations : Obtain the consent of pollution control authorities before discharging to wastewater treatment plants. Product should not be discharged to surface waters without a NPDES permit. : Dispose in a safe manner in accordance with local/national regulations. Avoid release to the environment. SECTION 14: Transport information In accordance with DOT Not hazardous for transport Additional information Other information : No supplementary information available. Transport by sea Air transport SECTION 15: Regulatory information US Federal regulations Bst DNA Polymerase, Exo- All chemical substances in this product are listed in the EPA (Environment Protection Agency) TSCA (Toxic Substances Control Act) Inventory or are exempt International regulations US State regulations California Proposition 65 This product does not contain any substances known to the state of California to cause cancer and/or reproductive harm 02/10/2016 Bst DNA Polymerase, Exo- 4/5

5 Glycerol ( ) U.S. - Massachusetts - Right To Know List U.S. - New Jersey - Right to Know Hazardous Substance List U.S. - Pennsylvania - RTK (Right to Know) List SECTION 16: Other information Indication of changes : Revision 1.0: New SDS Created. Revision date : 02/10/2016 Other information : Author: RJB. NFPA health hazard NFPA fire hazard NFPA reactivity : 0 - Exposure under fire conditions would offer no hazard beyond that of ordinary combustible materials. : 0 - Materials that will not burn. : 0 - Normally stable, even under fire exposure conditions, and are not reactive with water. HMIS III Rating Health : 0 Flammability : 0 Physical : 0 Personal Protection : This information is disclosed to the best of Lucigen s knowledge. This document does not constitute a contractual relationship with product end users or handlers with respect to the possible presence of hazards in this item. Disposal should be in accordance with applicable regional, national and local laws and regulations. 02/10/2016 Bst DNA Polymerase, Exo- 5/5