Tween-20 - ULTRA PURE

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1 Tween-20 - ULTRA PURE Catalog number: EC-607 Non-ionic surfactant for Western blotting and other molecular biology and biochemistry applications. Tween-20 is a Registered Trademark of ICI Americas

2 MATERIAL SAFETY DATA SHEET Date revised: 7/24/20 1. Chemical Product and Company Identification Product Name: Tween 20 Product Number: EC-607 Chemical names/description Polyoxyethylene sorbitan monolaurate; Polysorbate 20 ManufacturerNational Diagnostics305 Patton Drive Atlanta, GA Conforms to regulation (EC) no. EU 453/2010 Telephone Numbers(404) (800) Emergency Numbers Chemtrec (U.S. & Canada) (outside U.S. & Canada) 2. Composition/Information on Ingredients Component List Component % Comp. CAS # EC # TLV Polysorbate none established EEC LABEL SYMBOL AND CLASSIFICATION This product has no classification due to EU directives. 3. Hazards Identification Appearance and Odor Amber liquid EMERGENCY OVERVIEW - IMMEDIATE HAZARD MAY CAUSE IRRITATION TO SKIN AND EYES. EMERGENCY OVERVIEW - CHRONIC HAZARD WARNING TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED. Potential Health Effects Not expected to be a health hazard by inhalation. Large doses may produce abdominal spasms, diarrhea. May cause irritation or sensitization in sensitive individuals. May cause irritation. Signs and Symptoms of Overexposure Not expected to be a health hazard by inhalation. Abdominal spasms, diarrhea. Redness, swelling. 1/4

3 Pain, redness. Carcinogenicity Not listed as a known or anticipated carcinogen by NTP or IARC. Mutagenicity Reproductive Toxicity Teratogenic Effects Routes of Entry Target Organ Statement 4. First Aid Measures Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician. Give several glasses of water to drink to dilute. If large amounts were swallowed, get medical advice. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse. Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately. 5. Fire Fighting Measures Flash Point: 148 Flash Point Method: CC Flammable Limits: N.A. Autoignition Temperature: N.A. Extinguishing media Use media appropriate to the primary cause of fire. Protective Equipment In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Hazardous Combustion Products Carbon dioxide and carbon monoxide. Unusual Fire and Explosion Hazards Not considered an explosion hazard. 6. Accidental Release Measures Steps to be taken in case material is released or spilled Ventilate area of leak or spill. Contain and recover liquid when possible. Collect liquid in an appropriate container or absorb with an inert material (e.g., vermiculite, dry sand, earth), and place in a chemical waste container. Waste Disposal Method Disposal must be made in accordance with applicable federal, state, and local regulations. Personal Precautions Wear appropriate protective equipment as specified in Section Handling and Storage Handling Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Storage Keep in a tightly closed container, stored in a cooled, dry, ventilated area. Protect from physical damage. Isolate from incompatible 2/4

4 materials (section 10). Storage Temperature Room Temperature Disposal Observe all national, state, and local regulations regarding disposal. 8. Exposure Controls/Personal Protection Airborne Exposure Limits Component: Polysorbate 20 ACGIH Threshold Limit Value (TLV): none established OSHA Permissable Exposure Limit (PEL): None established Engineering Controls Not expected to require any special ventilation. Respiratory Protection Not expected to require personal respirator usage. Eye Protection Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area. Protection Wear protective gloves and clean body covering clothing. Other Control Measures N.A. 9. Physical Properties Boiling point ( o C) > 100C (> 212 F) Evaporation rate No information found Melting point ( o C) No information found Solubity in water Soluble Vapor pressure (mmhg) ph No information found Vapor density (Air = 1) No information found Specific gravity (H 2 O = 1) 1.11 % volatile by volume Stability and Reactivity Stability Stable under ordinary conditions of use and storage. Conditions to Avoid Incompatibles. Hazardous Decomposition Products Carbon dioxide and carbon monoxide may form when heated to decomposition. Hazardous Polymerization Will not occur under normal conditions of use (See Sections 10.4 & 10.5). Incompatibles Strong oxidizers, acids. 11. Toxicological Information Product LD50 Values Oral Rat LD50 (mg/kg) Dermal Rabbit LD50 (mg/kg): Component Cancer List Status NTP Carcinogen 3/4

5 Known Anticipated IARC Category Polysorbate 20 No No none 12. Ecological Information 13. Disposal Considerations Observe all national, state, and local regulations regarding disposal. 14. Transport Information DOT IATA IMO 15. Regulatory Information United States TSCA Regulatory Statement All intentional ingredients are listed on the TSCA Inventory. SARA 311/312 Hazard Categories Component Fire Pressure Reactivity Acute Chronic Polysorbate 20 No No No Yes No Europe EEC Regulatory All intentional ingredients are listed on the European EINECS Inventory. EEC LABEL SYMBOL AND CLASSIFICATION 16. Other Information MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users. 4/4

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