SAFETY DATA SHEET Protein A - Alkaline Phosphatase

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1 Revision Date 02/09/2015 Revision 1 SAFETY DATA SHEET SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identfer Product name Product No Relevant identfed uses of the substance or mixture and uses advised against Identfed uses Chemical reagent 1.3. Details of the supplier of the safety data sheet Supplier Innova Biosciences Ltd. Babraham Hall Babraham Cambridge CB22 3AT Tel. +44(0) Fax. +44(0) info@innovabiosciences.com 1.4. Emergency telephone number +44 (0) (Mon-Fri, 09:00-17:00, UK Time) SECTION 2: HAZARDS IDENTIFICATION 2.1. Classifcaton of the substance or mixture Classifcaton (EC 1272/2008) Physical and Chemical Hazards Human health Environment Classifcaton (1999/45/EEC) The Full Text for all R-Phrases and Hazard Statements are Displayed in Secton Label elements Label In Accordance With (EC) No. 1272/2008 No pictogram required. Supplemental label informaton 2.3. Other hazards EUH208 Contains ALKALINE PHOSPHATASE. May produce an allergic reacton. This product does not contain any PBT or vpvb substances. SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 3.2. Mixtures ALKALINE PHOSPHATASE < 1% CAS-No.: EC No.: Classifcaton (EC 1272/2008) Resp. Sens. 1 - H334 Classifcaton (67/548/EEC) R42. 1 / 6

2 The Full Text for all R-Phrases and Hazard Statements are Displayed in Secton 16. Compositon Comments The data shown are in accordance with the latest EC Directves. SECTION 4: FIRST AID MEASURES 4.1. Descripton of frst aid measures Inhalaton Move the exposed person to fresh air at once. May cause irritaton to the respiratory system. If symptoms of irritaton or sensitsaton occur (shortness of breath, wheezing or laboured coughing), call a doctor. Ingeston Immediately rinse mouth and provide fresh air. Get medical atenton if any discomfort contnues. Drink plenty of water. Skin contact Remove afected person from source of contaminaton. Wash the skin immediately with soap and water. Get medical atenton if any discomfort contnues. Eye contact Immediately fush with plenty of water for up to 15 minutes. Remove any contact lenses and open eyelids widely. If irritaton persists: Seek medical atenton and bring along these instructons Most important symptoms and efects, both acute and delayed Inhalaton May cause an asthma-like shortness of breath. Risk of sensitsaton or allergic reactons among sensitve individuals. Ingeston No specifc symptoms noted. Skin contact No specifc symptoms noted. Eye contact No specifc symptoms noted Indicaton of any immediate medical atenton and special treatment needed No specifc frst aid measures noted. Treat Symptomatcally. SECTION 5: FIREFIGHTING MEASURES 5.1. Extnguishing media Extnguishing media This product is not fammable. Use fre-extnguishing media appropriate for surrounding materials Special hazards arising from the substance or mixture Hazardous combuston products There are no antcipated hazardous decompositon products associated with this material. Unusual Fire & Explosion Hazards No unusual fre or explosion hazards noted Advice for frefghters Special Fire Fightng Procedures No specifc fre fghtng procedure given. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautons, protectve equipment and emergency procedures For personal protecton, see secton Environmental precautons Not relevant considering the small amounts used Methods and material for containment and cleaning up Avoid dust formaton. Absorb with inert, damp, non-combustble material, then fush area with water. Ensure sufcient ventlaton Reference to other sectons For waste disposal, see secton / 6

3 SECTION 7: HANDLING AND STORAGE 7.1. Precautons for safe handling Avoid inhalaton of dust. Avoid spilling, skin and eye contact Conditons for safe storage, including any incompatbilites Store at -20 C 7.3. Specifc end use(s) The identfed uses for this product are detailed in Secton 1.2. SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1. Control parameters Ingredient Comments No exposure limits noted for ingredient(s) Exposure controls Protectve equipment Engineering measures No specifc ventlaton requirements noted, except this product must not be used in a confned space without good ventlaton. Respiratory equipment Suitable respiratory protecton must be used at high concentratons. Hand protecton No specifc hand protecton noted, but gloves may stll be advisable. Eye protecton Wear approved chemical safety goggles where eye exposure is reasonably probable. Hygiene measures When using do not eat, drink or smoke. Wash hands at the end of each work shif and before eatng, smoking and using the toilet. SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 9.1. Informaton on basic physical and chemical propertes Appearance Freeze dried solid Colour White. Odour Odourless. Solubility Soluble in water. Inital boiling point and boiling range ( C) No informaton required. Meltng point ( C) No informaton required. Relatve density Not relevant Vapour density (air=1) Vapour pressure Evaporaton rate ph-value, Conc. Soluton Viscosity 3 / 6

4 Solubility Value (G/100G C) Decompositon temperature ( C) Odour Threshold, Lower Flash point ( C) Auto Igniton Temperature ( C) Flammability Limit - Lower(%) Flammability Limit - Upper(%) Partton Coefcient (N-Octanol/Water) Explosive propertes Oxidising propertes 9.2. Other informaton No informaton required. SECTION 10: STABILITY AND REACTIVITY Reactvity There are no known reactvity hazards associated with this product Chemical stability Stable under normal temperature conditons Possibility of hazardous reactons Conditons to avoid There are no known conditons that are likely to result in a hazardous situaton Incompatble materials Materials To Avoid No specifc, or groups of materials are likely to react to produce a hazardous situaton Hazardous decompositon products None under normal conditons. SECTION 11: TOXICOLOGICAL INFORMATION Informaton on toxicological efects Toxicological informaton Risk of sensitsaton or allergic reactons among sensitve individuals. Avoid inhalaton of dust. Inhalaton Risk of sensitsaton or allergic reactons among sensitve individuals. Ingeston May cause discomfort if swallowed. Skin contact Powder may irritate skin. 4 / 6

5 Eye contact Partcles in the eyes may cause irritaton and smartng. SECTION 12: ECOLOGICAL INFORMATION Ecotoxicity Not regarded as dangerous for the environment Toxicity No data available Persistence and degradability Degradability There are no data on the degradability of this product Bioaccumulatve potental Bioaccumulatve potental No data available on bioaccumulaton. Partton coefcient Mobility in soil Mobility: The product is soluble in water Results of PBT and vpvb assessment This product does not contain any PBT or vpvb substances Other adverse efects SECTION 13: DISPOSAL CONSIDERATIONS Waste treatment methods Dispose of waste and residues in accordance with local authority requirements. SECTION 14: TRANSPORT INFORMATION Road Transport Notes Rail Transport Notes Sea Transport Notes Air Transport Notes Not Classifed UN number UN proper shipping name Transport hazard class(es) Packing group Environmental hazards Environmentally Hazardous Substance/Marine Pollutant No. 5 / 6

6 14.6. Special precautons for user Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code SECTION 15: REGULATORY INFORMATION Safety, health and environmental regulatons/legislaton specifc for the substance or mixture Approved Code Of Practce Safety Data Sheets for Substances and Preparatons. EU Legislaton Regulaton (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registraton, Evaluaton, Authorisaton and Restricton of Chemicals (REACH), establishing a European Chemicals Agency, amending Directve 1999/45/EC and repealing Council Regulaton (EEC) No 793/93 and Commission Regulaton (EC) No 1488/94 as well as Council Directve 76/769/EEC and Commission Directves 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC, including amendments. Regulaton (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classifcaton, labelling and packaging of substances and mixtures, amending and repealing Directves 67/548/EEC and 1999/45/EC, and amending Regulaton (EC) No 1907/2006 with amendments Chemical Safety Assessment No chemical safety assessment has been carried out. SECTION 16: OTHER INFORMATION Revision Date 02/09/2015 Revision 1 Risk Phrases In Full R42 NC Hazard Statements In Full H334 May cause sensitsaton by inhalaton. May cause allergy or asthma symptoms or breathing difcultes if inhaled. Disclaimer This informaton relates only to the specifc material designated and may not be valid for such material used in combinaton with any other materials or in any process. Such informaton is, to the best of the company's knowledge and belief, accurate and reliable as of the date indicated. However, no warranty guarantee or representaton is made to its accuracy, reliability or completeness. It is the user's responsibility to satsfy himself as to the suitability of such informaton for his own partcular use. 6 / 6

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