THE PURITAN BENNETT 980 VENTILATOR CLINICAL APPLICATIONS LESSON PLAN

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1 THE PURITAN BENNETT 980 VENTILATOR CLINICAL APPLICATIONS LESSON PLAN

2 OVERVIEW This guide is provided as a convenience companion document to the Operator s Manual. It is not intended to replace the Operator s Manual, which should always be available while using the ventilator. It is important to familiarize yourself with all information in the Operator s Manual relevant to your institution s use of the ventilator, including on-screen help, instructions, warnings and cautions.

3 CONTENTS Puritan Bennett Leak Sync Software Noninvasive Ventilation Volume Control Plus Pressure Control Puritan Bennett BiLevel Software Puritan Bennett PAV *+ Software Tube Compensation Software Volume Support Puritan Bennett NeoMode 2.0 Software Puritan Bennett Proximal Flow Sensor 3 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

4 PURITAN BENNETT LEAK SYNC SOFTWARE

5 PROBLEM: WHERE DO LEAKS COME FROM? Patient interface ETT (cuffed, deflated cuff or cuffless) Trach tube (cuffed, deflated cuff or cuffless) Mask or other external interface Breathing circuit system 5 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

6 PROBLEM: COMMON LEAK CHALLENGES Auto-triggering Late cycling-off of pressure support and volume support breaths Overestimation of delivered tidal volume/flow The possible need for frequent manual adjustments 6 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

7 PROBLEM: LEAKS Studies show that air leaks occur in up to 70% of children and can lead to significant clinical consequences, including 1,2 : Inconsistent ventilatory delivery 1 Unreliable lung function testing 2 Inappropriate clinical assessment due to error in monitored volume 1 Increased work of breathing due to trigger asynchronies 2 Year Author Key Results 2010 Mahmoud 1 An air leak of 40% indicated the displayed V T was underestimated by 1.2 ml/kg, thus by about 24% of target V T (generally 5 ml/kg) Main 2 Leaks larger than 20% resulted in inconsistent tidal volume delivery and gross overestimation of compliance (C) and resistance (R) regardless of ventilator mode. 1. Mahmoud RA, Proquitté H, Fawzy N, Bührer C, Schmalisch G. Tracheal tube airleak in clinical practice and impact on tidal volume measurement in ventilated neonates. Pediatr Crit Care Med. 2011;12(2): Main E, Castle R, Stocks J, James I, Hatch D. The influence of endotracheal tube leak on the assessment of respiratory function in ventilated children. Intensive Care Med. 2001;27(11): Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

8 SOLUTION: PURITAN BENNETT LEAK SYNC SOFTWARE Leak Sync software may reduce leakrelated ventilation and monitoring problems* during both inspiration and exhalation Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 2013;58(12): (Puritan Bennett 840 Leak comp software was in the study). *Compared to when Leak Sync is off 8 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

9 SOLUTION: PURITAN BENNETT LEAK SYNC SOFTWARE Reduces auto-triggering and delayed cycling 1 Leak compensates the data values for V TI (displayed as V TL ) and V TE Servo-controls breath delivery based on leak-compensated values Works in VC+ and VS 1. Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 2013;58(12): (Puritan Bennett 840 Leak comp software was in the study). 9 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

10 PURITAN BENNETT LEAK SYNC SOFTWARE UPDATES Name: Leak Compensation changed to Leak Sync VC+ and VS added Defaults to ON with NIV and neonatal 10 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

11 POTENTIAL BENEFITS OF PURITAN BENNETT LEAK SYNC SOFTWARE May reduce manual adjustments of sensitivity settings 1 Improves triggering and cycling 2 Leak compensates the data values for inspiratory and expiratory volumes to make them more relevant to the clinical situation 1 Allows for VC+ and VS Enables avoidance of nuisance alarms May provide reassurance of appropriate level of ventilatory support by servocontrolling volume-targeted breath types from a leak-compensated V TI (displayed at V TL ) data value 1 1. Puritan Bennett TM 980 Series Ventilator Operator s Manual Leak Sync Addendum Page B-2 2. Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 2013;58(12): (Puritan Bennett 840 Leak comp software was in the study). 11 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

12 PURITAN BENNETT LEAK SYNC SOFTWARE SETUP Menu tab/setup/more settings Enabled or disabled Enabled by default with neonatal patient type and also when NIV is selected Set D SENS in L/min 12 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

13 DISPLAY CHANGES WITH LEAK SYNC SOFTWARE ENABLED LS on vent setup button D SENS = L/min (not %) V TL and V TE = estimated patient values Graphic displays estimated lung flows Data displayed: V LEAK %LEAK LEAK (leak rate@peep) 13 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

14 PERFORMANCE The Puritan Bennett 840 ventilator with Leak Compensation software outperformed all other ventilators included in the studies. 1 Invasive ventilation Noninvasive ventilation The Puritan Bennett 840 ventilator outperformed all other ventilators in this study by requiring fewer breaths to achieve synchronization during increasing and decreasing leaks. 1 The study demonstrated wide variations between the ability of ventilators to compensate for an air leak during noninvasive ventilation. 1 The Puritan Bennett 840 and Philips Respironics TM * V60 ventilators were the only ventilators in this study that adapted well to increasing or decreasing leaks Oto J, Marchese A, Kacmarek M. A comparison of leak compensation in acute care ventilators during invasive ventilation: a lung model study. Respir Care. 2013;58: Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

15 HOW PURITAN BENNETT LEAK SYNC SOFTWARE WORKS Defaults on: NIV or Neonatal Defaults off: INV/Pediatric or Adult Adjusts within ~ 3 breaths V TL and V TE compensated display Flow/volume graphics leak compensated Bias flow automatically adjusted 15 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

16 CAPABILITIES AND LIMITATIONS Capabilities Neonate, pediatric and adult invasive and non-invasively Dynamic compensation of leaks during invasive and noninvasive ventilation Limitations Leak Sync software not active with: Tube compensation (TC) Proportional Assist * Ventilation (PAV *+ software) 16 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

17 NONINVASIVE VENTILATION

18 PROBLEM: INVASIVE AND NONINVASIVE VENTILATION PRESENT CHALLENGES Mechanical ventilation may lead to significant asynchrony. 1 Leaks may impact patient tolerance to NIV. 2 Leaks may result in monitoring errors, breath management issues, and trigger and cycle asynchrony Mahmoud RA, Proquitté H, Fawzy N, Bührer C, Schmalisch G. Tracheal tube airleak in clinical practice and impact on tidal volume measurement in ventilated neonates. Pediatr Crit Care Med. 2011;12(2): Vignaux L, Vargas F, Roeseler J, et al. Patient-ventilator asynchrony during non-invasive ventilation for acute respiratory failure: a multicenter study. Intensive Care Med. 2009;35(5): Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

19 SOLUTION: NON-INVASIVE VENTILATION (NIV) WITH PURITAN BENNETT LEAK SYNC SOFTWARE NIV ventilation selection Use with mask or other leak-prone patient interface Works with various modes/breath types Leak Sync software enabled 19 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

20 POTENTIAL BENEFITS OF NIV WITH PURITAN BENNETT LEAK SYNC SOFTWARE Help patients tolerate NIV so they can continue using NIV Help avoid complications associated with intubation/artificial airways 1 1. Epstein S. Should a Patient Be Extubated and Placed on Noninvasive Ventilation After Failing a Spontaneous Breathing Trial? Respir Care 2010;55(2): Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

21 NIV SETUP Setup button Menu tab/vent NIV Shows applicable settings CPAP mode is available Flow trigger T I SPONT limit D SENS defaults to OFF 21 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

22 HOW NIV SOFTWARE WORKS NIV-compatible selection of mode and breath types (NEO CPAP added) is available Volume alarms are disabled to reduce nuisance alarms Leak Sync software automatically enabled 22 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

23 NIV CAPABILITIES AND LIMITATIONS Only flow triggering is available. Capabilities Stable respiratory drive Neonatal Pediatric Adult Limitations Not available with: Tube compensation (TC) BiLevel VC+ and VS Proportional Assist * Ventilation Plus (PAV *+ software) breath types 23 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

24 VOLUME CONTROL PLUS

25 PROBLEM: FIXED FLOW PATTERNS MAY RESULT IN DISCOMFORT AND ASYNCHRONY 25 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

26 SOLUTION: VOLUME CONTROL PLUS (VC+) VC+ breaths deliver a variable flow. The ventilator manages inspiratory pressure to achieve the desired tidal volume target. 26 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

27 POTENTIAL BENEFITS OF VC+ Unlike standard VC, VC+: Provides variable flow delivery and volume Uses the lowest pressure necessary for volume delivery Escalates pressure if volume delivery decreases Active valve accommodates breathing variations. 27 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

28 VC+ SETUP Select: Gender and height or predicted body weight (PBW) Invasive vent type AC or SIMV mode VC+ mandatory breath type Adjust all available settings. Set all appropriate alarms. 28 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

29 HOW VC+ SOFTWARE WORKS AND ALARM STRATEGY Variable flow with active exhalation valve Titration of pressure 1 3 cmh 2 O/breath Alarm strategy P PEAK limit (determines max target pressure) P PEAK limit Volume not delivered V TI limit 29 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

30 TROUBLESHOOTING INADEQUATE V T DELIVERY Check that T I is long enough. Check that Rise Time is fast enough. Check that the set tidal volume is not too high in comparison with the P PEAK limit. Check for auto-peep causing P PEAK limit and resolve. 30 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

31 CAPABILITIES AND LIMITATIONS Capabilities Neonate, pediatric and adult Leak Sync software compatible Limitations Invasive only High effort may result in regulating of pressure down to undesirable levels. Leaks without Leak Sync software enabled may result in regulating of pressure down to undesirable levels. 31 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

32 PRESSURE CONTROL

33 TWO PROBLEMS Fixed flow patterns in VC may result in discomfort and asynchrony. VC+ may not always provide a consistent delivered pressure. 33 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

34 SOLUTION: PRESSURE CONTROL (PC) PC breaths deliver variable flow and volume. The inspiratory pressure target remains constant. 34 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

35 POTENTIAL BENEFITS OF PC Mean airway pressure more consistent while allowing more natural breathing. 35 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

36 PC SETUP Enter the patient s gender and height or predicted body weight (PBW). Select INV or NIV. Touch AC or SIMV mode. Touch the PC mandatory breath type. Adjust all available settings. Set all appropriate alarms. 36 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

37 HOW TO USE THE TIMING PADLOCKS The user determines whether to set Inspiratory Time, I:E Ratio or Expiratory Time as the primary setting. Changes in the preset rate will not alter the primary variable set in the timing padlocked area. 37 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

38 HOW PC SOFTWARE WORKS Mandatory, assisted/controlled pressure-based breath INV or NIV The user sets inspiratory time, inspiratory pressure/peep and pressure rise. The ventilator manages flow to meet the patient s needs and control pressure delivery. 38 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

39 CAPABILITIES AND LIMITATIONS Capabilities May be used with neonate, pediatric and adult patients. May be combined with Leak Sync. Limitations Tidal volume is variable. 39 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

40 PURITAN BENNETT BILEVEL SOFTWARE

41 TWO PROBLEMS The limitations of volume control may lead to additional sedation. 1 Inverse ratios and monitoring are limitations in traditional PCV. 1. Pohlman M. Excessive tidal volume from breath stacking during lung-protective ventilation for acute lung injury. Crit Care Med. 2008;36: Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

42 SOLUTION: PURITAN BENNETT BILEVEL SOFTWARE Mandatory-assisted and spontaneous-assisted pressurebased breath types Active valve Strategies for boosting mean airway pressure Normal I:E or extended inverse available (>4:1) 42 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

43 POTENTIAL CLINICAL BENEFITS OF PURITAN BENNETT BILEVEL SOFTWARE Flow and volume variable Active valve Conventional or APRV style of breath timing Potential for improved oxygenation 1 Potential for reduction in sedation 1 1. Putensen C. et al. Long-Term Effects of Spontaneous Breathing During Ventilatory Support in Patients with Acute Lung Injury. Am J Respir Crit Care Med Vol 164. pp 43 49, Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

44 PURITAN BENNETT BILEVEL SOFTWARE SETUP Enter gender and height or predicted body weight (PBW). Touch Invasive. Touch BiLevel mode. Adjust available settings. Note: P H : Above ambient, not above PEEP; must be set at least 5 above P L Spontaneous Type: TC or PS Set all appropriate alarms. 44 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

45 PURITAN BENNETT BILEVEL SOFTWARE SETUP: TIMING PADLOCK TO LOCK RELEASE TIME User determines the primary setting. Options: T H (Time High) T H ratio to T L (Time High to Time Low ratio) T L (Time Low) Changes in set frequency will not alter the primary variable set in the timing padlocked area. 45 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

46 PURITAN BENNETT BILEVEL SOFTWARE SETUP P H : Pressure during the T H period P L : Pressure during the T L period When T H :T L > 4:1, with the T L period locked, changes in set f will change the T H, but the T L will remain constant regardless of patient effort period to accommodate the new f setting while maintaining the set T L period. 46 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

47 HOW PURITAN BENNETT BILEVEL SOFTWARE WORKS Two pressure levels, breath availability and active valve Conventional or APRV breath timing Alarm strategy P PEAK (peak pressure) may be 1 to 2 cmh 2 O higher than set pressure 47 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

48 PURITAN BENNETT BILEVEL SOFTWARE: SPONTANEOUS SUPPORT OPTIONS Pressure support Works on P L and P H P L + PS = target pressure May be left at 0 cmh 2 0 Tube Compensation 48 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

49 CAPABILITIES AND LIMITATIONS Capabilities Neonate, pediatric, adult APRV inverse ratio settings Support Spont breaths with PS, TC Limitations Only invasive Limited respiratory mechanics 49 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

50 DESCRIBE CHANGES THAT MAY IMPACT OXYGENATION P H High Pressure T H High Pressure Time Habashi NM. Other approaches to open-lung ventilation: airway pressure release ventilation. Crit Care Med. 2005;33(3 Suppl):S Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

51 PURITAN BENNETT PAV *+ SOFTWARE

52 PROBLEM: WHEN THE VENTILATOR CONTROLS BREATHS INSTEAD OF THE PATIENT, ATROPHY OF DIAPHRAGM FIBERS HAPPENS RAPIDLY DUE TO DISUSE Levine et al. Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. NEJM. 2008;358: Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

53 PROBLEM: PATIENT-VENTILATOR ASYNCHRONY IS PREVALENT 24% of mechanically ventilated patients exhibit patient-ventilator asynchrony in >10% of their respiratory efforts. Thille A. Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med. 2006;32: Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

54 PROBLEM: ASYNCHRONY MAY LEAD TO THE USE OF SEDATION Asynchrony Sedation Prolonged ventilation time 1 Possible muscle atrophy 2 and VAP 3 Weaning is delayed 1. Kollef M et al. The use of continuous intravenous sedation is associated with prolongation of mechanical ventilation. Chest. 1998;114: Levine S et al. Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans. NEJM. 2008;358: Rello J et al. Epidemiology and outcomes of ventilator-associated pneumonia in a large US database. Chest. 2002;122: Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

55 PROBLEM: ASSOCIATED ASYNCHRONY COSTS 24% of ICU patients exhibit asynchrony in greater than 10% of their breaths. 1 [ 24% ] Asynchrony is associated with 18 extra days on the ventilator: duration of mechanical ventilation 7 (3-20) days vs. 25 (9-42) days p=0.005 ventilation (days; IQR). 1 [ 18 days ] Average cost per day in the ICU for a patient receiving mechanical ventilation is $4, [ $72,000 ] 1. Thille A et al. Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med. 2006;32: Dasta J et al. Daily cost of an intensive care unit day: the contribution of mechanical ventilation. Crit Care Med. 2005;33: Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

56 SOLUTION: PURITAN BENNETT PAV *+ SOFTWARE Monitors patient s demand breath by breath Monitors compliance and resistance Allows variable volume, flow, inspiratory time and pressure Promotes natural breathing* *Compared to VC, VC+ and PS 56 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

57 POTENTIAL BENEFITS OF PURITAN BENNETT PAV *+ SOFTWARE Encourages use of the diaphragm 1 Increases support as the patient s demand increases Improves patient-ventilator synchrony 1,2 May help the clinician better manage a patient s work of breathing 3 1. Xirouchaki N. et al. Proportional assist ventilation with load-adjustable gain factors in critically ill patients: comparison with pressure support. Int Care Med. 2008;34(11): Costa R. A physiologic comparison of proportional assist ventilation with load-adjustable gain factors (PAV+) versus pressure support ventilation (PSV) Intensive Care Med (2011) 37: Eumorfia Kondili, George Prinianakis, Christina Alexopoulou, Eleftheria Vakouti, Maria Klimathianaki, Dimitris Georgopoulos Respiratory Load compensation during mechanical ventilation-proportional assist ventilation with load-adjustable gain factors versus pressure support Intensive Care Med DOI /s Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

58 PURITAN BENNETT PAV *+ SOFTWARE SETUP Enter gender and height or predicted body weight ( 25 kg). Touch: Invasive vent type SPONT mode PAV *+ Select % Support, PEEP and FiO 2. Select tube type. Adjust the tube ID (6-10 mm ID). Adjust the alarms. 58 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

59 PURITAN BENNETT PAV *+ SOFTWARE KEY ALARMS P PEAK V TI limit V E or V T 59 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

60 PURITAN BENNETT PAV *+ SOFTWARE CHANGES PA to PAV *+ description Default support starts at 70% Support Two graphs and WOB bar Enhanced calculation of compliance and resistance 60 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

61 HOW PURITAN BENNETT PAV *+ SOFTWARE WORKS: MEASUREMENTS Measures values that create work Assesses compliance and resistance (4-10 breaths with an automatic plateau) Measures flow and volume every 5 msec Uses the equation of motion 61 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

62 HOW PURITAN BENNETT PAV *+ SOFTWARE WORKS: SETTINGS AND MONITORED PARAMETERS % Support, PEEP and O 2 % Tube size and type Monitors: Compliance, resistance and PEEP I Work of breathing bar WOB TOT and WOB PT Elastic and resistance work Estimated lung pressure shadow trace Flow and volume waveforms 62 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

63 PURITAN BENNETT PAV *+ SOFTWARE ALARM STRATEGY High inspired tidal volume ( V TI ) High circuit pressure ( P PEAK ) PAV STARTUP TOO LONG PAV R&C NOT ASSESSED Set all other traditional alarms 63 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

64 SUMMARY OF HOW PURITAN BENNETT PAV *+ SOFTWARE WORKS PAV *+ software measures work variables. The primary settings are % Support, PEEP and O 2 %. The software amplifies patient efforts to offset the total work of breathing. The software adjusts delivered pressure within the same breath. The breath stops when patient inspiratory flow ceases. Delivered pressure adjusts dynamically to patient effort. 64 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

65 CAPABILITIES AND LIMITATIONS Capabilities Intact respiratory drive 25 kg (55 lb.) or greater 6.0 I.D. tube or greater Limitations Apnea Oversedation Abnormal respiratory drive Leaks <25 kg (55 lb.) Severe air trapping Pneumatic nebulizer Not available with NIV 65 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

66 TUBE COMPENSATION

67 PROBLEM: IMPOSED WOB FROM A TRACH OR AN ET TUBE An endotracheal or tracheostomy tube can impose an increased work of breathing. 1 Pressure Support limitations: Fixed delivery pressure approach T-Piece trials reduce the monitoring capabilities. 1. Maeda Y. Does the tube-compensation function of two modern mechanical ventilators provide effective work of breathing relief? Critical Care 2003, 7:R92-R97 67 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

68 SOLUTION: TUBE COMPENSATION (TC) Tube Compensation (TC) assists the patient in overcoming the flow resistance of the artificial airway. TC software supports spontaneous breaths. Only to the point of overcoming the artificial airways TC may reduce the work of breathing Maeda Y. Does the tube-compensation function of two modern mechanical ventilators provide effective work of breathing relief? Critical Care 2003, 7:R92-R97 68 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

69 POTENTIAL BENEFITS OF TUBE COMPENSATION Provide variable pressure with variable effort. Reduce the imposed work associated with artificial airways. 1 Allow for enhanced monitoring compared to the T-Piece approach. 1. Maeda Y. Does the tube-compensation function of two modern mechanical ventilators provide effective work of breathing relief? Critical Care 2003, 7:R92-R97 69 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

70 TUBE COMPENSATION SETUP Select TC for spontaneous type. In particular, mention: % Support: 10% to 100% Tube I.D. Tube type P PEAK V TI 70 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

71 HOW TUBE COMPENSATION SOFTWARE WORKS Supports spontaneous breathing in SPONT, BiLevel and SIMV. TC checks the flow rate every 5 ms. TC uses flow, the % Support setting and a look-up table to determine delivered pressure. % Support settings are from 10% to 100% (in 5% increments). 71 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

72 TC-SPECIFIC ALARM STRATEGY P PEAK Inspired tidal volume All of typical alarms 72 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

73 CAPABILITIES AND LIMITATIONS Capabilities Intact respiratory drive 7.0 kg (15.4 lb.) or greater 4.5 I.D. tube or bigger Limitations Oversedation NeoMode <7.0 kg (15.4 lb.) <4.5 I.D. tube Apnea 73 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

74 VOLUME SUPPORT

75 PROBLEM: LIMITATIONS OF PRESSURE SUPPORT Pressure support does not provide a target tidal volume. Pressure support does not downregulate pressure automatically. 75 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

76 SOLUTION: VOLUME SUPPORT (VS) Clinician can set a target tidal volume. Automated pressure delivery is based on inspired volume. VS provides variable flow. 76 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

77 POTENTIAL BENEFITS OF VOLUME SUPPORT Encourages the use of the diaphragm Automatically decreases support pressure if target tidal volume is exceeded (1 3 cmh 2 O) Increases pressure if the patient s ability to take an adequate breath is compromised (1 3 cmh 2 O) 1. Sassoon C. Assist Control Mechanical Ventilation Attenuates Ventilator-induced Diaphragmatic Dysfunction. Am J Respir Crit Care Med Vol 170. pp , Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

78 COMPARING VOLUME SUPPORT TO PRESSURE SUPPORT Feature Volume Support Pressure Support Lowest pressure for the set volume Yes No Escalates if needed Yes No Adjusts for changes in Raw and C Yes No 78 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

79 VOLUME SUPPORT SETUP Select SPONT mode Select VS for spontaneous type Select: V T SUPP Trigger setting Oxygen % Rise % E SENS PEEP V TI P PEAK 79 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

80 HOW VOLUME SUPPORT SOFTWARE WORKS VS varies the inspiratory pressure to deliver the operator-set target tidal volume. During VS, the inspiratory pressure target cannot be lower than PEEP cmh 2 O and cannot exceed the P PEAK limit - 3 cmh 2 O. Pressure adjust a max of +/- 3 cmh 2 O/breath if needed. Test breath at startup. VS startup is displayed in the GUI s prompt area. 80 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

81 VS-SPECIFIC ALARM STRATEGY P PEAK limit (determines max target pressure) Volume not delivered V TI limit 81 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

82 CAPABILITIES AND LIMITATIONS Capabilities Neonatal to adult Spontaneously breathing patients Invasive ventilation only SPONT mode only Limitations Oversedation Apnea High effort may result in regulating of pressure down to undesirable levels. Leaks without Leak Sync software enabled may result in regulating of pressure down. NIV 82 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

83 PURITAN BENNETT NEOMODE 2.0 SOFTWARE

84 GENERAL PROBLEM Small tidal volume requirements Ability to use AC and SIMV to ventilate with NIV Auto-triggering and delayed cycling 1 Management of nuisance alarms with CPAP Reducing excessive oxygen exposure Excessive tidal volume delivery 1. Oto J et al. A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study Respir Care 013;58(12): Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

85 POTENTIAL SOLUTION: PURITAN BENNETT NEOMODE 2.0 SOFTWARE Puritan Bennett Leak Sync software A wide spectrum of modes both INV and NIV Volume targeted availability down to 2.0 ml Assist Control (VC, VC+ and PC) SIMV (VC, VC+ - Dual Mode and PC) BiLevel software Spontaneous Volume Support Dual Mode Pressure Support Assist Control (VC, PC) SIMV (VC, PC) Spontaneous (PS) CPAP 85 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

86 POTENTIAL SOLUTION: PURITAN BENNETT NEOMODE 2.0 SOFTWARE A NIV CPAP-specific mode with nuisance alarm management A configurable temporary elevate oxygen feature Enhanced monitoring of C 20 /C and ml/kg 86 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

87 POTENTIAL SOLUTION/BENEFITS OF PURITAN BENNETT NEOMODE 2.0 SOFTWARE One machine for all patient sizes Possible reduced use of invasive ventilation Automatic management of leaks Reduced alarms in the NICU with NCPAP Better management of oxygen exposure Intended delivered volume managed by monitoring C 20 /C PBW/kg 87 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

88 PURITAN BENNETT NEOMODE 2.0 SOFTWARE SETUP Install the neonatal adapter door and the single patient use neonatal expiratory filter. Connect a neonatal breathing circuit to the ventilator. Select the neonatal breathing circuit type in Short Self-Test (SST). Neonatal-specific settings and safety boundaries are activated. 88 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

89 PURITAN BENNETT NEOMODE 2.0 SOFTWARE SETUP Select actual patient weight Range for neonates is 0.3 kg to 7.0 kg (0.66 lb. to 15 lb.) Select INV or NIV and modes Includes A/C, SIMV, Spont, BiLevel and CPAP Breath type VC, VC+ or PC All other specific settings Configurable elevated FiO 2 Leak Sync software automatically enabled 89 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

90 HOW NEOMODE 2.0 SOFTWARE WORKS: ALARM STRATEGIES IN CPAP When in NeoMode 2.0 mode, if NIV CPAP is used: V E TOT, V TE SPONT and V TI alarms are not available. V E and V TE displays are not available. T A can be adjusted but defaults to off to avoid inadvertent alarms. Adjust the D SENS alarm. 90 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

91 CAPABILITIES AND LIMITATIONS OF PURITAN BENNETT NEOMODE 2.0 SOFTWARE Indications: 0.3 kg (0.66 lb.) and above V T 2 ml and above Neonatal breathing circuit Neonatal adapter door and neonatal expiratory filter Limitations: Pediatric or adult breathing circuit >7.0 kg (15 lb.) PBW 91 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

92 PURITAN BENNETT PROXIMAL FLOW SENSOR

93 PROBLEMS: ACCURATE GRAPHICS AND PROXIMAL FLOW SENSOR ISSUES Circuit volume affecting graphs Calibrations during ventilation Water contamination of Proximal Flow Sensor 93 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

94 SOLUTION: PURITAN BENNETT PROXIMAL FLOW SENSOR AND MONITORING SOFTWARE Measures flow and volume reflected at the patient wye Displays both proximal flow and proximal pressure Uses proximal flow values in the display of graphics. Requires no manual calibration Weight 6.6 g; dead space <1 ml 94 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

95 POTENTIAL BENEFITS OF THE PURITAN BENNETT PROXIMAL FLOW SENSOR Improved graphics for patient management Improved patient data 95 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

96 PURITAN BENNETT PROXIMAL FLOW OPTION COMPONENTS Proximal Flow Hardware Proximal Flow Sensor 96 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

97 PURITAN BENNETT PROXIMAL FLOW SENSOR SETUP: ENABLING/DISABLING THE SENSOR To disable or enable the Proximal Flow Option: 1. Touch the Configure wrench icon 2. Touch the Options tab 3. Touch the Prox tab 4. Touch the Enabled or Disabled button 5. Touch Accept Periodic expiratory phase purging occurs regularly for accurate measurements. 97 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

98 PROXIMAL FLOW SENSOR SETUP WITH PURITAN BENNETT NEOMODE 2.0 SOFTWARE Installed during the SST (prompts are given) Two connections: Install monitoring end at the patient circuit wye Install connector end on the ventilator s front panel behind a clear door Neonatal invasive ventilation only 98 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

99 PURITAN BENNETT PROXIMAL FLOW SENSOR SETUP: ALARM STRATEGY Alarms respond to values monitored with the flow sensor Breaths are controlled from the internal flow sensors (prox flow values are for monitoring only) Prox inoperative 99 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

100 HOW THE PURITAN BENNETT NEONATAL PROXIMAL FLOW SENSOR WORKS Measures flows, pressures and tidal volumes Requires NeoMode 2.0 software option Purge and auto-zero Waveform Monitoring: P CIRCY V Y V TY Monitored data: V TIY V TLY V TEY V TE SPONTY V TE MANDY V ETOTY LEAK Y 100 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

101 COMPARING THE VALUES FOR LEAK AND LEAK Y Patient + Circuit Patient 101 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

102 CAPABILITIES AND LIMITATIONS Capabilities Measuring flows, pressures and tidal volumes of invasively ventilated neonatal patients PBW of 0.3 kg (0.66 lb) to 7.0 kg (15.4 lb) using ET tube sizes from 2.5 mm to 4.0 mm Limitations Non-invasive (NIV) Pediatric and adult ET >4.0 mm PBW >7.0 kg (15.4 lb) Nebulized medications 2016 Medtronic. All rights reserved. Medtronic, Medtronic logo and Further, Together are trademarks of Medtronic. Proportional Assist and PAV are registered trademarks of The University of Manitoba, Canada. Used under license. TM * Third party brands are trademarks of their respective owners. All other brands are trademarks of a Medtronic company. 102 Puritan Bennett TM 980 Ventilator Clinical Applications Lesson Plan June 1, 2015

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