Material Safety Data Sheet

Transcription

1 Conforms to ANSI Z400.1 Standard (United States) 1. Product name Material uses Material Safety Data Sheet Product and company identification Supplier/Manufacturer Stratagene Micro RNA Isolation Kit, Catalog # Agilent Technologies, Inc State Highway 71 West Cedar Creek, TX Part No. (Chemical Kit) Part No M Sodium acetate Validation date In case of emergency 2. Emergency overview Stratagene Micro RNA Isolation Kit, Catalog # Analytical reagent ml 50 ml 50 ml 2 M Sodium acetate 5 ml 0.05 ml 03/30/ Hazards identification Physical state Liquid. Liquid. Liquid. 2 M Sodium acetate Liquid. Liquid. Odor Characteristic. Alcohol-like. 2 M Sodium acetate OSHA/HCS status This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ). This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ). This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ). 2 M Sodium acetate This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ). While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR ), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. Date of issue 03/30/2011 1/22

2 2. Hazards identification Signal word DANGER! WARNING! WARNING! 2 M Sodium acetate DANGER! No signal word. Hazard statements COMBUSTIBLE LIQUID AND VAPOR. MAY BE FATAL IF ABSORBED THROUGH SKIN. HARMFUL IF SWALLOWED. CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. MAY CAUSE ALLERGIC SKIN REACTION. MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. HARMFUL IF INHALED. MAY BE HARMFUL IF ABSORBED THROUGH SKIN OR IF SWALLOWED. FLAMMABLE LIQUID AND VAPOR. INHALATION CAUSES HEADACHES, DIZZINESS, DROWSINESS AND NAUSEA AND MAY LEAD TO UNCONSCIOUSNESS. CAUSES EYE IRRITATION. MAY CAUSE SKIN IRRITATION. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. 2 M Sodium acetate CAUSES RESPIRATORY TRACT, DIGESTIVE TRACT, EYE AND SKIN BURNS. MAY BE HARMFUL IF ABSORBED THROUGH SKIN. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. Precautions Keep away from heat, sparks and flame. Do not breathe vapor or mist. Do not ingest. Do not get in eyes or on skin or clothing. Use only with adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash thoroughly after handling. Do not breathe vapor or mist. Do not ingest. Do not get in eyes. Avoid contact with skin and clothing. Use only with adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash thoroughly after handling. Keep away from heat, sparks and flame. Do not breathe vapor or mist. Avoid contact with eyes, skin and clothing. Use only with adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash thoroughly after handling. 2 M Sodium acetate Do not breathe vapor or mist. Do not ingest. Do not get in eyes or on skin or clothing. Use only with adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash thoroughly after handling. Avoid prolonged contact with eyes, skin and clothing. Date of issue 03/30/2011 2/22

3 2. Hazards identification Routes of entry Dermal contact. Inhalation. Ingestion. 2 M Sodium acetate Potential acute health effects Inhalation Ingestion Irritating to respiratory system. Toxic by inhalation. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure. Can cause central nervous system (CNS) depression. 2 M Sodium acetate Corrosive to the respiratory system. Toxic if swallowed. Harmful if swallowed. Can cause central nervous system (CNS) depression. 2 M Sodium acetate Corrosive to the digestive tract. Causes burns. Skin Very toxic in contact with skin. Irritating to skin. May cause sensitization by skin contact. Harmful in contact with skin. Slightly irritating to the skin. 2 M Sodium acetate Corrosive to the skin. Causes burns. Harmful in contact with skin. Eyes Severely irritating to eyes. Risk of serious damage to eyes. Irritating to eyes. 2 M Sodium acetate Corrosive to eyes. Causes burns. Potential chronic health effects Chronic effects May cause target organ damage, based on animal data. Once sensitized, a severe allergic reaction may occur when subsequently exposed to very low levels. Contains material that may cause target organ damage, based on animal data. 2 M Sodium acetate Contains material that may cause target organ damage, based on animal data. Carcinogenicity 2 M Sodium acetate Mutagenicity 2 M Sodium acetate Date of issue 03/30/2011 3/22

4 2. Hazards identification Teratogenicity 2 M Sodium acetate Developmental effects 2 M Sodium acetate Fertility effects 2 M Sodium acetate Target organs May cause damage to the following organs upper respiratory tract, skin, eyes. Contains material which may cause damage to the following organs lungs, liver, gastrointestinal tract, upper respiratory tract, skin, central nervous system (CNS), eye, lens or cornea. 2 M Sodium acetate Contains material which may cause damage to the following organs lungs, upper respiratory tract, skin, eye, lens or cornea, teeth. Over-exposure signs/symptoms Inhalation Adverse symptoms may include the following respiratory tract irritation coughing Adverse symptoms may include the following nausea or vomiting headache drowsiness/fatigue dizziness/vertigo unconsciousness 2 M Sodium acetate Adverse symptoms may include the following respiratory tract irritation coughing Ingestion 2 M Sodium acetate Adverse symptoms may include the following stomach pains Skin Adverse symptoms may include the following irritation redness Adverse symptoms may include the following irritation redness 2 M Sodium acetate Adverse symptoms may include the following pain or irritation redness Date of issue 03/30/2011 4/22

5 2. Hazards identification blistering may occur Eyes Adverse symptoms may include the following pain or irritation watering redness Adverse symptoms may include the following pain or irritation watering redness 2 M Sodium acetate Adverse symptoms may include the following pain watering Medical conditions aggravated by overexposure See toxicological information (Section 11) 3. redness Pre-existing skin disorders and disorders involving any other target organs mentioned in this MSDS as being at risk may be aggravated by over-exposure to this product. None known. Pre-existing disorders involving any target organs mentioned in this MSDS as being at risk may be aggravated by over-exposure to this product. 2 M Sodium acetate Pre-existing disorders involving any target organs mentioned in this MSDS as being at risk may be aggravated by over-exposure to this product. Composition/information on ingredients None known. Name CAS number % 2-Mercaptoethanol Guanidinium thiocyanate M Sodium acetate Sodium acetate Acetic acid There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section. 4. First aid measures Eye contact Date of issue 03/30/2011 Call medical doctor or poison control center immediately. Check for and remove any contact lenses. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention immediately. Check for and remove any contact lenses. 5/22

6 4. First aid measures Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention immediately. Check for and remove any contact lenses. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention immediately. 2 M Sodium acetate Check for and remove any contact lenses. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention immediately. Check for and remove any contact lenses. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention if symptoms occur. Skin contact Call medical doctor or poison control center immediately. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention immediately. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention immediately. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention immediately. 2 M Sodium acetate In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention immediately. In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention if symptoms occur. Inhalation Move exposed person to fresh air. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately. Move exposed person to fresh air. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately. Move exposed person to fresh air. If not breathing, if breathing is irregular or if respiratory arrest Date of issue 03/30/2011 6/22

7 4. First aid measures Ingestion occurs, provide artificial respiration or oxygen by trained personnel. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately. 2 M Sodium acetate Move exposed person to fresh air. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately. Move exposed person to fresh air. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms occur. Wash out mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. Wash out mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. Wash out mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. 2 M Sodium acetate Wash out mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately. Wash out mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if symptoms occur. Protection of first-aiders No action shall be taken involving any personal risk or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water before removing it, or wear gloves. No action shall be taken involving any personal risk or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water before removing it, or wear gloves. No action shall be taken involving any personal risk Date of issue 03/30/2011 7/22

8 4. First aid measures Notes to physician 5. or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. 2 M Sodium acetate No action shall be taken involving any personal risk or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water before removing it, or wear gloves. No action shall be taken involving any personal risk or without suitable training. No specific treatment. Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been ingested or inhaled. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours. No specific treatment. Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been ingested or inhaled. 2 M Sodium acetate No specific treatment. Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been ingested or inhaled. Fire-fighting measures Flammability of the product Extinguishing media No specific treatment. Treat symptomatically. Contact poison treatment specialist immediately if large quantities have been ingested or inhaled. Combustible liquid. In a fire or if heated, a pressure increase will occur and the container may burst, with the risk of a subsequent explosion. The vapor/gas is heavier than air and will spread along the ground. Vapors may accumulate in low or confined areas or travel a considerable distance to a source of ignition and flash back. In a fire or if heated, a pressure increase will occur and the container may burst. Flammable liquid. In a fire or if heated, a pressure increase will occur and the container may burst, with the risk of a subsequent explosion. The vapor/gas is heavier than air and will spread along the ground. Vapors may accumulate in low or confined areas or travel a considerable distance to a source of ignition and flash back. Runoff to sewer may create fire or explosion hazard. 2 M Sodium acetate In a fire or if heated, a pressure increase will occur and the container may burst. In a fire or if heated, a pressure increase will occur and the container may burst. Date of issue 03/30/2011 8/22

9 5. Fire-fighting measures Suitable Use dry chemical, CO2, water spray (fog) or foam. Use an extinguishing agent suitable for the surrounding fire. Use dry chemical, CO2, water spray (fog) or foam. 2 M Sodium acetate Use an extinguishing agent suitable for the surrounding fire. Use an extinguishing agent suitable for the surrounding fire. Not suitable Do not use water jet. None known. Do not use water jet. 2 M Sodium acetate None known. None known. Special exposure hazards Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Move containers from fire area if this can be done without risk. Use water spray to keep fire-exposed containers cool. No action shall be taken involving any personal risk or without suitable training. Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Move containers from fire area if this can be done without risk. Use water spray to keep fire-exposed containers cool. 2 M Sodium acetate No action shall be taken involving any personal risk or without suitable training. No action shall be taken involving any personal risk or without suitable training. Hazardous thermal Decomposition products may include the following decomposition products materials carbon dioxide carbon monoxide sulfur oxides Decomposition products may include the following materials carbon dioxide carbon monoxide nitrogen oxides sulfur oxides Decomposition products may include the following materials carbon dioxide carbon monoxide 2 M Sodium acetate Decomposition products may include the following materials carbon dioxide carbon monoxide metal oxide/oxides Special protective equipment for fire-fighters Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode. Date of issue 03/30/2011 9/22

10 6. Accidental release measures Personal precautions Environmental precautions No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Shut off all ignition sources. No flares, smoking or flames in hazard area. Do not breathe vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see Section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Do not breathe vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see Section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Shut off all ignition sources. No flares, smoking or flames in hazard area. Do not breathe vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see Section 8). 2 M Sodium acetate No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Do not breathe vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see Section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Put on appropriate personal protective equipment (see Section 8). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Date of issue 03/30/ /22

11 6. Accidental release measures Methods for cleaning up 7. Handling and storage Handling 2 M Sodium acetate Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if watersoluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Use sparkproof tools and explosion-proof equipment. Dispose of via a licensed waste disposal contractor. Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if watersoluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if watersoluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Use sparkproof tools and explosion-proof equipment. Dispose of via a licensed waste disposal contractor. 2 M Sodium acetate Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if watersoluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if watersoluble. Alternatively, or if water-insoluble, absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Put on appropriate personal protective equipment (see Section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. Persons with a history of skin sensitization problems should not be employed in any process in which this product is used. Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Do not enter storage areas and confined spaces unless adequately ventilated. Date of issue 03/30/ /22

12 7. Handling and storage Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Store and use away from heat, sparks, open flame or any other ignition source. Use explosion-proof electrical (ventilating, lighting and material handling) equipment. Use non-sparking tools. Take precautionary measures against electrostatic discharges. To avoid fire or explosion, dissipate static electricity during transfer by grounding and bonding containers and equipment before transferring material. Empty containers retain product residue and can be hazardous. Do not reuse container. Put on appropriate personal protective equipment (see Section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. Put on appropriate personal protective equipment (see Section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin and clothing. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Do not enter storage areas and confined spaces unless adequately ventilated. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Store and use away from heat, sparks, open flame or any other ignition source. Use explosionproof electrical (ventilating, lighting and material handling) equipment. Use non-sparking tools. Take precautionary measures against electrostatic discharges. To avoid fire or explosion, dissipate static electricity during transfer by grounding and bonding containers and equipment before transferring material. Empty containers retain product residue and can be hazardous. Do not reuse container. 2 M Sodium acetate Put on appropriate personal protective equipment (see Section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and Date of issue 03/30/ /22

13 7. Handling and storage smoking. Remove contaminated clothing and protective equipment before entering eating areas. Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. Put on appropriate personal protective equipment (see Section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. Storage Store in accordance with local regulations. Store in a segregated and approved area. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Eliminate all ignition sources. Separate from oxidizing materials. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. Store in accordance with local regulations. Store in a segregated and approved area. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Eliminate all ignition sources. Separate from oxidizing materials. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. 2 M Sodium acetate Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept Date of issue 03/30/ /22

14 7. Handling and storage upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. 8. Exposure controls/personal protection Ingredient 2-Mercaptoethanol Exposure limits AIHA WEEL (United States, 5/2010). Absorbed through skin. TWA 0.2 ppm 8 hour(s). ACGIH TLV (United States, 2/2010). STEL 400 ppm 15 minute(s). TWA 200 ppm 8 hour(s). NIOSH REL (United States, 6/2009). STEL 1225 mg/m³ 15 minute(s). STEL 500 ppm 15 minute(s). TWA 980 mg/m³ 10 hour(s). TWA 400 ppm 10 hour(s). OSHA PEL (United States, 6/2010). TWA 980 mg/m³ 8 hour(s). TWA 400 ppm 8 hour(s). OSHA PEL 1989 (United States, 3/1989). STEL 1225 mg/m³ 15 minute(s). STEL 500 ppm 15 minute(s). TWA 980 mg/m³ 8 hour(s). TWA 400 ppm 8 hour(s). 2 M Sodium acetate Acetic acid ACGIH TLV (United States, 2/2010). STEL 37 mg/m³ 15 minute(s). STEL 15 ppm 15 minute(s). TWA 25 mg/m³ 8 hour(s). TWA 10 ppm 8 hour(s). NIOSH REL (United States, 6/2009). STEL 37 mg/m³ 15 minute(s). STEL 15 ppm 15 minute(s). TWA 25 mg/m³ 10 hour(s). TWA 10 ppm 10 hour(s). OSHA PEL (United States, 6/2010). TWA 25 mg/m³ 8 hour(s). TWA 10 ppm 8 hour(s). OSHA PEL 1989 (United States, 3/1989). TWA 25 mg/m³ 8 hour(s). TWA 10 ppm 8 hour(s). Date of issue 03/30/ /22

15 8. Exposure controls/personal protection Recommended monitoring procedures Engineering measures Hygiene measures Personal protection Respiratory Hands Eyes Skin Environmental exposure controls Other protection 9. If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment. Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists or dusts. Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels. Physical and chemical properties Physical state Liquid. Liquid. Liquid. 2 M Sodium acetate Liquid. Liquid. Flash point Closed cup 74 C (165.2 F) Open cup 74 C (165.2 F) Closed cup 11.7 C (53.1 F) Open cup C (53.3 F) [Tagliabue.] 2 M Sodium acetate Auto-ignition temperature 295 C (563 F) 399 C (750.2 F) 2 M Sodium acetate Flammable limits Lower 2.3% Upper 18% Lower 2% Upper 12% 2 M Sodium acetate Date of issue 03/30/ /22

16 9. Physical and chemical properties Color Colorless. Colorless. 2 M Sodium acetate Odor Characteristic. Alcohol-like. 2 M Sodium acetate ph 2 M Sodium acetate 4 Boiling/condensation 157 C (314.6 F) point 82.5 C (180.5 F) 2 M Sodium acetate 100 C (212 F) Melting/freezing point -100 C (-148 F) C (-128 F) 2 M Sodium acetate 0 C (32 F) Specific gravity M Sodium acetate Vapor pressure 0.13 kpa (0.975 mm Hg) [20 C] 4.4 kpa (33 mm Hg) [20 C] 2 M Sodium acetate Vapor density Volatility Odor threshold Evaporation rate 2.7 [Air = 1] 2.07 [Air = 1] 2 M Sodium acetate 2 M Sodium acetate 2 M Sodium acetate 1.7 (butyl acetate = 1) 2 M Sodium acetate Date of issue 03/30/ /22

17 9. Viscosity Solubility 10. Physical and chemical properties Stability and reactivity Chemical stability Conditions to avoid Materials to avoid 2 M Sodium acetate Easily soluble in the following materials cold water and hot water. Soluble in the following materials cold water and hot water. Easily soluble in the following materials cold water and hot water. 2 M Sodium acetate Easily soluble in the following materials cold water and hot water. Easily soluble in the following materials cold water and hot water. The product is stable. The product is stable. The product is stable. 2 M Sodium acetate The product is stable. The product is stable. Avoid all possible sources of ignition (spark or flame). Do not pressurize, cut, weld, braze, solder, drill, grind or expose containers to heat or sources of ignition. Do not allow vapor to accumulate in low or confined areas. Avoid all possible sources of ignition (spark or flame). Do not pressurize, cut, weld, braze, solder, drill, grind or expose containers to heat or sources of ignition. Do not allow vapor to accumulate in low or confined areas. 2 M Sodium acetate Reactive or incompatible with the following materials oxidizing materials Reactive or incompatible with the following materials oxidizing materials 2 M Sodium acetate Hazardous decomposition products Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous decomposition products should not be produced. 2 M Sodium acetate Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, Date of issue 03/30/ /22

18 10. Stability and reactivity Possibility of hazardous reactions 11. Toxicological information Acute toxicity hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous reactions will not occur. Under normal conditions of storage and use, hazardous reactions will not occur. Under normal conditions of storage and use, hazardous reactions will not occur. 2 M Sodium acetate Under normal conditions of storage and use, hazardous reactions will not occur. Under normal conditions of storage and use, hazardous reactions will not occur. Product/ingredient name Result Species Dose Exposure 2-Mercaptoethanol LD50 Dermal Rabbit 200 mg/kg - LD50 Oral Rat 244 mg/kg - LD50 Dermal Rabbit mg/kg - LD50 Oral Rat 5000 mg/kg - 2 M Sodium acetate Sodium acetate LC50 Inhalation Vapor Rat >30000 mg/m3 1 hours LD50 Oral Rat 3530 mg/kg - Acetic acid LC50 Inhalation Vapor Rat mg/m3 4 hours LD50 Dermal Rabbit 1060 mg/kg - LD50 Oral Rat 3310 mg/kg - Chronic toxicity Conclusion/Summary Irritation/Corrosion Carcinogenicity Conclusion/Summary Classification Product/ingredient name Result Species Score Exposure Observation 2-Mercaptoethanol Eyes - Severe irritant Rabbit Eyes - Moderate irritant Rabbit Eyes - Severe irritant Rabbit Skin - Mild irritant Rabbit M Sodium acetate Acetic acid Eyes - Mild irritant Rabbit Skin - Mild irritant Human Skin - Mild irritant Rabbit Skin - Severe irritant Rabbit Sensitizer Conclusion/Summary Date of issue 03/30/ /22

19 11. Toxicological information Product/ingredient name ACGIH IARC EPA NIOSH NTP A Mutagenicity Conclusion/Summary Teratogenicity Conclusion/Summary Reproductive toxicity Conclusion/Summary OSHA Other adverse symptoms 2 M Sodium acetate 12. Ecotoxicity Ecological information Aquatic ecotoxicity Product/ingredient name May cause long-term adverse effects in the aquatic environment. Result Species Acute LC to ug/l Crustaceans - Crangon crangon Marine water Acute LC50 > ug/l Fish - Gambusia affinis - 20 to 30 mm Exposure 48 hours 96 hours 2 M Sodium acetate Sodium acetate Acute EC50 >1000 mg/l Daphnia 48 hours Acetic acid Acute EC ug/l Fresh water Daphnia - Daphnia magna - 48 hours Neonate - <24 hours Acute LC ul/l Marine water Crustaceans - Artemia sp. 48 hours Acute LC ug/l Fresh water Fish - Lepomis macrochirus to 7.2 cm to 3.9 g 96 hours Conclusion/Summary Persistence/degradability Partition coefficient n- octanol/water Product/ingredient name Test Result Dose 2 M Sodium acetate Sodium acetate - 99 % - Readily - 28 days 10.2 mg/l Activated sludge Other adverse effects M Sodium acetate Inoculum Date of issue 03/30/ /22

20 13. Disposal considerations Waste disposal The generation of waste should be avoided or minimized wherever possible. Significant quantities of waste product residues should not be disposed of via the foul sewer but processed in a suitable effluent treatment plant. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible. This material and its container must be disposed of in a safe way. Care should be taken when handling emptied containers that have not been cleaned or rinsed out. Empty containers or liners may retain some product residues. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Disposal should be in accordance with applicable regional, national and local laws and regulations. Local regulations may be more stringent than regional or national requirements. The information presented below only applies to the material as supplied. The identification based on characteristic(s) or listing may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to determine the toxicity and physical properties of the material generated to determine the proper waste identification and disposal methods in compliance with applicable regulations. Refer to Section 7 HANDLING AND STORAGE and Section 8 EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. 14. Transport information Regulatory information UN number Proper shipping name Classes PG* Label Additional information DOT UN3316 Chemical kits 9 II Limited quantity Yes. Packaging instruction Passenger aircraft Quantity limitation 10 kg Cargo aircraft Quantity limitation 10 kg Special provisions 15 IMDG UN3316 CHEMICAL KIT. Marine pollutant (2- Mercaptoethanol) 9 II Emergency schedules (EmS) F-A, _S-P_ IATA UN3316 Chemical kit 9 Date of issue 03/30/2011 II Passenger and Cargo Aircraft Quantity limitation 10 kg Packaging instructions 915 Cargo Aircraft Only 20/22

21 14. Transport information Quantity limitation 10 kg Packaging instructions 915 Limited Quantities - Passenger Aircraft Quantity limitation 1 kg Packaging instructions Y915 PG* Packing group 15. Regulatory information HCS Classification Combustible liquid Highly toxic material Irritating material Sensitizing material Target organ effects Toxic material Flammable liquid Irritating material Target organ effects 2 M Sodium acetate Corrosive material Target organ effects Not regulated. U.S. Federal regulations TSCA 8(a) IUR Partial exemption United States inventory (TSCA 8b) All components are listed or exempted. SARA 302/304/311/312 extremely hazardous substances No products were found. SARA 302/304 emergency planning and notification No products were found. SARA 302/304/311/312 hazardous chemicals ; Sodium acetate; Acetic acid SARA 311/312 MSDS distribution - chemical inventory - hazard identification Fire hazard, Immediate (acute) health hazard, Delayed (chronic) health hazard; Sodium acetate Immediate (acute) health hazard; Acetic acid Fire hazard, Immediate (acute) health hazard, Delayed (chronic) health hazard Clean Water Act (CWA) 311 Acetic acid Clean Air Act Section 112(b) Hazardous Air Pollutants (HAPs) Clean Air Act Section 602 Class I Substances Clean Air Act Section 602 Class II Substances DEA List I Chemicals (Precursor Chemicals) DEA List II Chemicals (Essential Chemicals) SARA 313 Form R - Reporting requirements Not listed Not listed Not listed Not listed Not listed Product name CAS number Concentration Date of issue 03/30/ /22

22 15. Regulatory information Supplier notification SARA 313 notifications must not be detached from the MSDS and any copying and redistribution of the MSDS shall include copying and redistribution of the notice attached to copies of the MSDS subsequently redistributed. State regulations 16. Massachusetts New York New Jersey Pennsylvania California Prop. 65 No products were found. Other information Label requirements Date of issue Date of previous issue Version Notice to reader The following components are listed ACETIC ACID; ISOPROPYL ALCOHOL The following components are listed Acetic acid The following components are listed ACETIC ACID; ETHANOIC ACID; ISOPROPYL ALCOHOL; 2-PROPANOL The following components are listed ACETIC ACID; 2-PROPANOL COMBUSTIBLE LIQUID AND VAPOR. MAY BE FATAL IF ABSORBED THROUGH SKIN. HARMFUL IF SWALLOWED. CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. MAY CAUSE ALLERGIC SKIN REACTION. MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. HARMFUL IF INHALED. MAY BE HARMFUL IF ABSORBED THROUGH SKIN OR IF SWALLOWED. FLAMMABLE LIQUID AND VAPOR. INHALATION CAUSES HEADACHES, DIZZINESS, DROWSINESS AND NAUSEA AND MAY LEAD TO UNCONSCIOUSNESS. CAUSES EYE IRRITATION. MAY CAUSE SKIN IRRITATION. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. 2 M Sodium acetate CAUSES RESPIRATORY TRACT, DIGESTIVE TRACT, EYE AND SKIN BURNS. MAY BE HARMFUL IF ABSORBED THROUGH SKIN. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. 03/30/ /09/ Indicates information that has changed from previously issued version. Disclaimer The information contained in this document is based on Agilent s state of knowledge at the time of preparation. No warranty as to its accurateness, completeness or suitability for a particular purpose is expressed or implied. Date of issue 03/30/ /22