Safety Data Sheet. SECTION 1: Identification of the substance/mixture and of the company/undertaking

Transcription

1 Safety Data Sheet SECTION 1: Identification of the substance/mixture and of the company/undertaking Identification of the substance or mixture Product code Product name AM9720 ACID PHENOL:CHLOROFORM 100 ML Company/undertaking identification Life Technologies Corporation 5781 Van Allen Way PO Box 6482 Carlsbad, CA Life Technologies 5250 Mainway Drive Burlington, ONT CANADA L7L 6A4 800/ hour Emergency Response: Outside of the U.S Country specific Emergency Number (if available): CHEMTREC Brazil (Rio De Janeiro) +(55) (português) For research use only. Not intended for human or animal diagnostic or therapeutic uses. GHS - Classification Signal Word DANGER SECTION 2: Hazards identification Health hazards Acute oral toxicity Category 3 Acute dermal toxicity Category 3 Acute Inhalation Toxicity - Vapors Category 3 Skin corrosion/irritation Category 1 Revision date 20-Aug-2015 Page 1 / 8

2 Serious eye damage/eye irritation Category 1 Specific target organ systemic toxicity (repeated exposure) Category 1 Carcinogenicity Category 2 Reproductive Toxicity Category 2 Mutagenicity Mutagenic category 2 Physical hazards Not Hazardous Hazard Statements H301 + H311 + H331 - Toxic if swallowed, in contact with skin or if inhaled H314 - Causes severe skin burns and eye damage H372 - Causes damage to organs through prolonged or repeated exposure H361 - Suspected of damaging fertility or the unborn child H351 - Suspected of causing cancer H341 - Suspected of causing genetic defects H411 - Toxic to aquatic life with long lasting effects Precautionary Statements P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P201 - Obtain special instructions before use P260 - Do not breathe dust/fume/gas/mist/vapors/spray P273 - Avoid release to the environment Principle Routes of Exposure Potential Health Effects eyes Skin inhalation Ingestion Specific effects Carcinogenic effects Mutagenic effects Reproductive toxicity Sensitization Target Organ Effects Risk of serious damage to eyes. Causes burns. Toxic in contact with skin. Toxic by inhalation. Toxic if swallowed. Possibly Carcinogenic. Contains a known or suspected mutagen. May cause adverse reproductive effects - such as birth defect, miscarriages, or infertility. Not Applicable. Liver. Kidney. HMIS Health 4 * Chronic Hazard Flammability 0 Reactivity 0 Revision date 20-Aug-2015 Page 2 / 8

3 SECTION 3: Composition/information on ingredients Component CAS-No EINECS-No Weight % ( ) Chloroform ( ) We recommend handling all chemicals with caution. SECTION 4: First aid measures Skin contact Wash off immediately with plenty of water. In the case of skin irritation or allergic reactions see a physician. Eye contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Consult a physician. Call a physician if irritation persists. Ingestion Rinse mouth. Consult a physician if necessary. Do not induce vomiting without medical advice. inhalation Remove to fresh air. Consult a physician if necessary. Most important symptoms and effects, both acute and delayed H301 + H311 + H331 - Toxic if swallowed, in contact with skin or if inhaled, H314 - Causes severe skin burns and eye damage, H372 - Causes damage to organs through prolonged or repeated exposure, H361 - Suspected of damaging fertility or the unborn child, H351 - Suspected of causing cancer, H341 - Suspected of causing genetic defects, H411 - Toxic to aquatic life with long lasting effects Notes to Physician Treat symptomatically. SECTION 5: Firefighting measures Suitable extinguishing media Special protective equipment for firefighters Specific hazards arising from the chemical Foam. Dry powder. Dry chemical. Carbon dioxide (CO2). Water. Wear self-contained breathing apparatus and protective suit. Not known SECTION 6: Accidental release measures Personal precautions Methods for cleaning up Avoid exposure to vapor. Avoid breathing vapors or mists. Ensure adequate ventilation. Avoid contact with skin, eyes or clothing. Use personal protection equipment. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Sweep up and shovel into suitable containers for disposal. Clean contaminated surface thoroughly. Environmental precautions Should not be released into the environment. Prevent product from entering drains. See Section 12 for more information. Handling Storage SECTION 7: Handling and storage Always wear reccommended Personal Protective Equipment. Avoid contact with skin, eyes or clothing. Use only in ventilated areas. Keep in properly labeled containers. Keep container tightly closed in a dry and Revision date 20-Aug-2015 Page 3 / 8

4 well-ventilated place. Keep away from combustible material. SECTION 8: Exposure controls/personal protection Exposure Limits Chemical Name OSHA PEL OSHA PEL (Ceiling) ACGIH OEL (TWA) ACGIH OEL (STEL) 5 ppm None 5 ppm None 19 mg/m 3 Chloroform None 50 ppm 240 mg/m 3 10 ppm None Engineering measures Ensure adequate ventilation, especially in confined areas. Personal Protective Equipment Personal Protective Equipment requirements are dependent on the user institution's risk assessment and are specific to the risk assessment for each laboratory where this material may be used. Respiratory protection In case of insufficient ventilation, wear suitable respiratory equipment. Hand protection Eye protection Skin and Body Protection Hygiene measures Environmental exposure controls Impervious gloves. Wear safety glasses with side shields (or goggles). Lightweight protective clothing. Handle in accordance with good industrial hygiene and safety practice. Should not be released into the environment. Prevent product from entering drains. SECTION 9: Physical and chemical properties General information Form Liquid Appearance No information available Odor Mixture has not been tested Odor Threshold Mixture has not been tested Boiling point / boiling range C F Melting point / melting range C F flash point C F Autoignition Temperature C F Evaporation rate Flammability (solid, gas) Oxidizing properties Mixture has not been tested Water solubility soluble Upper explosion limit Lower explosion limit Partition coefficient: n-octanol/water Vapor Pressure vapor density Viscosity Mixture has not been tested ph value 4.5 Revision date 20-Aug-2015 Page 4 / 8

5 SECTION 10: Stability and reactivity Stability Materials to avoid Possibility of hazardous reactions Hazardous decomposition products polymerization Conditions to avoid Stable under normal conditions. No information available. Hazardous reaction has not been reported No information available. Hazardous polymerization does not occur. None under normal processing. SECTION 11: Toxicological information Acute Toxicity Chemical Name LD50 (oral,rat/mouse) LD50 (dermal,rat/rabbit) LC50 (inhalation,rat/mouse) = 317 mg/kg (Rat) = 340 mg/kg =316mg/m 3 (Rat) (Rat) Chloroform = 695 mg/kg (Rat) = 450 mg/kg (Rat) =47702mg/kg(Rat) =47702mg/m 3 (Rat) Principle Routes of Exposure Potential Health Effects eyes Skin inhalation Ingestion Carcinogenic effects Mutagenic effects Reproductive toxicity Sensitization Target Organ Effects Risk of serious damage to eyes. Causes burns. Toxic in contact with skin. Toxic by inhalation. Toxic if swallowed. Possibly Carcinogenic. Contains a known or suspected mutagen. May cause adverse reproductive effects - such as birth defect, miscarriages, or infertility. No information available. Liver Kidney SECTION 12: Ecological information Ecotoxicity Daphnia magna. Desmodesmus subspicatus. Chronic aquatic toxicity Category 2. Mobility see log Pow. Biodegradation Readily biodegradable. Bioaccumulation Material does not bioaccumulate. Chemical Name Freshwater Algae Data Desmodesmus subspicatus EC mg/l (72 h) Water Flea Data Freshwater Fish Species Data Microtox Data log Pow Daphnia magna EC50 logpow mg/l (48 h) Daphnia magna Pseudokirchneriella EC mg/l Revision date 20-Aug-2015 Page 5 / 8

6 Chloroform subcapitata EC mg/l (96 h) Desmodesmus subspicatus EC50=560 mg/l (48 h) (48 h) Daphnia magna EC50=29 mg/l (48 h) logpow2 SECTION 13: Disposal considerations Dispose of contents/containers in accordance with local regulations. SECTION 14: Transport information IATA Proper Shipping Name Toxic liquid, organic, n.o.s. (/Chloroform solution) Hazard Class 6.1 Subsidiary class None Packing group III UN-No 2810 Environmental hazards No Revision date 20-Aug-2015 Page 6 / 8

7 SECTION 15: Regulatory information Component ( ) Chloroform ( ) US TSCA Listed Listed US Federal Regulations SARA 313 This product contains the following toxic chemical(s) subject to the notification requirements of section 313 of Title III of the Superfund Amendments and Reauthorization Act of This law requires certain manufacturers to report on annual emissions of specified chemicals and chemical categories. Please note that if you repackage, or otherwise redistribute, this product to industrial customers, a notice similar to this one should be sent to those customers:. Chemical Name CAS-No Weight % SARA Threshold Values Chloroform Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61) This product contains the following HAPs:. Component CAS-No Weight % HAPS data Present ( ) Chloroform ( ) Present US State Regulations California Proposition 65 This product contains the following Proposition 65 chemicals. Chemical Name CAS-No Weight % Category Chloroform Carcinogen Developmental WHMIS Hazard Class D1B - Toxic materials E - Corrosive material D2A - Very toxic materials This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR. SECTION 16: Other information Reason for revision SDS sections updated. For research use only. "The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Revision date 20-Aug-2015 Page 7 / 8

8 Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE" End of Safety Data Sheet Revision date 20-Aug-2015 Page 8 / 8