1. Substance/preparation and manufacturer/supplier identification
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1 Safety data sheet Page: 1/8 1. Substance/preparation and manufacturer/supplier identification C00498 HYALURONIC FILLING SPHERES Use: cosmetic ingredient Manufacturer/supplier: BASF Australia Limited (ABN ) Level 12, 28 Freshwater Place Southbank Victoria 3006, AUSTRALIA Telephone: Telefax number: Emergency information: BASF Emergency Advice Number: (24h) [within Australia] BASF Emergency Advice Number: [outside Australia] 2. Hazard identification Classification of the substance and mixture: No need for classification according to GHS criteria for this product. Label elements and precautionary statement: The product does not require a hazard warning label in accordance with GHS criteria. Other hazards which do not result in classification: No specific dangers known, if the regulations/notes for storage and handling are considered.
2 Page: 2/8 3. Composition/information on ingredients Chemical nature INCI Name: Ethylhexyl Palmitate, Trihydroxystearin, Sodium Hyaluronate. Chemical nature : Microsphere based on vegetal compounds in gel suspension No particular hazards known. 4. First-Aid Measures General advice: Remove contaminated clothing. If inhaled: Keep patient calm, remove to fresh air. On skin contact: Wash thoroughly with soap and water. On contact with eyes: Wash affected eyes for at least 15 minutes under running water with eyelids held open. On ingestion: Rinse mouth and then drink plenty of water. Note to physician: Symptoms: The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11., Further important symptoms and effects are so far not known. Hazards: No hazard is expected under intended use and appropriate handling. Treatment: Symptomatic treatment (decontamination, vital functions). 5. Fire-Fighting Measures Suitable extinguishing media: water spray, foam, dry powder, carbon dioxide Specific hazards: Product is not combustible or explosive. Special protective equipment: Wear self-contained breathing apparatus and chemical-protective clothing. Further information: Dispose of fire debris and contaminated extinguishing water in accordance with official regulations.
3 Page: 3/8 6. Accidental Release Measures Personal precautions: Information regarding personal protective measures see, section 8. Environmental precautions: Do not discharge into drains/surface waters/groundwater. Discharge into the environment must be avoided. Methods for cleaning up or taking up: For small amounts: Pick up with suitable absorbent material. Dispose of absorbed material in accordance with regulations. For large amounts: Dike spillage. Pick up with suitable appliance and dispose of. 7. Handling and Storage Handling Handle in accordance with good industrial hygiene and safety practice. Protection against fire and explosion: No special precautions necessary. Storage Suitable materials for containers: High density polyethylene (HDPE), glass Further information on storage conditions: Keep container tightly closed and dry; store in a cool place. To be mixed before using. Close containers after use. Storage stability: Storage temperature: C Avoid freezing. 8. Exposure controls and personal protection Components with occupational exposure limits No occupational exposure limits known. Personal protective equipment Respiratory protection: Respiratory protection not required. Hand protection: Suitable chemical resistant safety gloves (EN 374) also with prolonged, direct contact (Recommended: Protective index 6, corresponding > 480 minutes of permeation time according to EN 374): E.g. nitrile rubber (0.4 mm), chloroprene rubber (0.5 mm), butyl rubber (0.7 mm) etc. Supplementary note: The specifications are based on tests, literature data and information of glove manufacturers or are derived from similar substances by analogy. Due to many conditions (e.g.
4 Page: 4/8 temperature) it must be considered, that the practical usage of a chemical-protective glove in practice may be much shorter than the permeation time determined through testing. Eye protection: Safety glasses with side-shields (frame goggles) (e.g. EN 166) Body protection: Body protection must be chosen based on level of activity and exposure. General safety and hygiene measures: Handle in accordance with good industrial hygiene and safety practice. No eating, drinking, smoking or tobacco use at the place of work. Handle in accordance with good industrial hygiene and safety practice. 9. Physical and Chemical Properties Form: Colour: Odour: Odour threshold: ph value: liquid white product specific not applicable not applicable Boiling range: C (1,013 hpa) Flash point: < 130 C (ASTM D93) Evaporation rate: Value can be approximated from Henry's Law Constant or vapor pressure. Flammability (solid/gas): not flammable Lower explosion limit: For liquids not relevant for classification and labelling. Upper explosion limit: For liquids not relevant for classification and labelling. Ignition temperature: not determined Thermal decomposition: No decomposition if stored and handled as prescribed/indicated. Self ignition: not self-igniting Vapour pressure: not determined
5 Page: 5/8 Density: 0.84 g/cm3 (20 C) Relative vapour density (air): not applicable (internal method) Solubility in water: insoluble (20 C) Partitioning coefficient n-octanol/water (log Pow): not determined Viscosity, dynamic: 260 mpa.s (internal method) Viscosity, kinematic: not determined Other Information: If necessary, information on other physical and chemical parameters is indicated in this section., No further information available. 10. Stability and Reactivity Conditions to avoid: No special precautions other than good housekeeping of chemicals. Thermal decomposition: No decomposition if stored and handled as prescribed/indicated. Substances to avoid: metal alloys Hazardous reactions: No hazardous reactions if stored and handled as prescribed/indicated. Hazardous decomposition products: No hazardous decomposition products if stored and handled as prescribed/indicated. 11. Toxicological Information Acute toxicity Assessment of acute toxicity: Virtually nontoxic after a single ingestion. The product has not been tested. The statement has been derived from substances/products of a similar structure or composition. Experimental/calculated data: LD50 rat (oral): > 2,000 mg/kg (OECD Guideline 423) Data of a comparable product Irritation Assessment of irritating effects:
6 Page: 6/8 Not irritating to the skin. Not irritating to the eyes. The product has not been tested. The statement has been derived from substances/products of a similar structure or composition. Respiratory/Skin sensitization Assessment of sensitization: Skin sensitizing effects were not observed in animal studies. The product has not been tested. The statement has been derived from substances/products of a similar structure or composition. Germ cell mutagenicity Assessment of mutagenicity: The chemical structure does not suggest a specific alert for such an effect. Carcinogenicity Assessment of carcinogenicity: Based on the ingredients there is no suspicion of a carcinogenic effect in humans. Reproductive toxicity Assessment of reproduction toxicity: The chemical structure does not suggest a specific alert for such an effect. Developmental toxicity Assessment of teratogenicity: The chemical structure does not suggest a specific alert for such an effect. Repeated dose toxicity and Specific target organ toxicity (repeated exposure) Assessment of repeated dose toxicity: None known 12. Ecological Information Ecotoxicity Assessment of aquatic toxicity: At the present state of knowledge, no negative ecological effects are expected. The product has not been tested. The statement has been derived from the properties of the individual components. Mobility Assessment transport between environmental compartments: Study not necessary due to exposure considerations. Persistence and degradability Assessment biodegradation and elimination (H2O): Study not necessary due to exposure considerations. Bioaccumulation potential
7 Page: 7/8 Assessment bioaccumulation potential: Study not necessary due to exposure considerations. 13. Disposal Considerations Observe national and local legal requirements. 14. Transport Information Domestic transport: Not classified as a dangerous good under transport regulations Sea transport IMDG Not classified as a dangerous good under transport regulations Air transport IATA/ICAO Not classified as a dangerous good under transport regulations 15. Regulatory Information Other regulations If other regulatory information applies that is not already provided elsewhere in this safety data sheet, then it is described in this subsection. Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP): Not Scheduled Registration status: AICS, AU released / listed 16. Other Information Vertical lines in the left hand margin indicate an amendment from the previous version.
8 Page: 8/8 The data contained in this safety data sheet are based on our current knowledge and experience and describe the product only with regard to safety requirements. The data do not describe the product's properties (product specification). Neither should any agreed property nor the suitability of the product for any specific purpose be deduced from the data contained in the safety data sheet. It is the responsibility of the recipient of the product to ensure any proprietary rights and existing laws and legislation are observed.
SECTION 1: Identification of the substance/mixture and of the company/undertaking
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