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SDS- Lysis Buffer Page 1 of 8 Safety Data Sheet 1121 5 th Street NW Washington, DC 20001 www.edvotek.com Version 2 Revision Date 08/27/2014 1. PRODUCT AND COMPANY IDENTIFICATION Product name: Lysis Buffer Product Number: Brand: Edvotek Supplier: Edvotek 1121 5 th Street NW Washington, DC 20001 Telephone: 1-800-338-6835 or 202-370-1500 Fax: 202-370-1501 Emergency Phone #: 202-370-1500 2. HAZARDS IDENTIFICATION Emergency Overview GHS Clasiffication Eye irritation (Category 2A) Signal Word Irritant Pictogram Hazard(s) Statements H319 Causes serious eye irritation Precautionary statement(s) P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. HMIS Classification: Health hazard: 2 Flammability: 0 Physical hazard: 0 1

SDS- Lysis Buffer Page 2 of 8 NFPA Rating: Health hazard: 2 Fire: 0 Reactivity Hazard: 0 Potential Health Effects: Inhalation May be harmful if inhaled. Causes respiratory tract irritation Skin May be harmful if absorbed through skin. cause skin irritation. Eyes May cause eye irritation. Ingestion May be harmful if swallowed. 3. 4. COMPOSITION/INFORMATION ON INGREDIENTS Mixture of the substances listed bellow with nonhazardous additions. Chemical name EC No. CAS No Concentration EDTA 200-449-4 60-00-4 -- Water 5. FIRST AID MEASURES General information No special measures required. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult doctor in case of complaints. In case of skin contact Immediately wash off with soap and plenty of water. Get medical attention if symptoms develop. In case of eye contact Flush eyes with water as a precaution. Get medical attention immediately if irritation persists. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Get medical attention if symptoms develop. 2

SDS- Lysis Buffer Page 3 of 8 6. FIREFIGHTING MEASURES Conditions of flammability Not flammable or combustible. Suitable extinguishing media Use water spray, alcohol resistant foam, dry chemical or carbon dioxide. Special protective equipment for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Hazardous combustion products Carbon oxides, Nitrogen oxides (NOx). 7. ACCIDENTAL RELEASE MEASURES Personal precautions Prevent skin/eye contact. Use personal protective equipment as needed. Environmental precautions Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and materials for containment and cleaning up Clean up spills immediately. Use absorbent materials if needed and dispose into a chemical waste container. 8. HANDLING AND STORAGE Precautions for safe handling No special measures necessary. Good laboratory technique should be used when handling. Conditions for safe storage No special measures necessary. Store at room temperature. Incompatible Products No known 3

SDS- Lysis Buffer Page 4 of 8 8. EXPOSURE CONTROLS/ PERSONAL PROTECTION Personal protective equipment Respiratory protection Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection Wear protective gloves. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Eye protection Avoid eye contact with this material. Wear chemical safety goggles. Skin and body protection Use chemical gloves as needed. Use clean protective body covering clothing as needed to minimize contact with clothing and skin. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash and dry hands at the end of workday. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form liquid Colour colorless Odor no data avilable Safety data ph Melting point/freezing point Boiling point Flash point 4

SDS- Lysis Buffer Page 5 of 8 Ignition temperature Autoignition Temperature Lower explosion limit Upper explosion limit Vapour pressure Density (water=1) Water solubility Partition coefficient: n-octanol/water Relative vapour Density Odour Threshold Evaporation rate no data avilable 10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions No further relevant data available. Conditions to avoid No further relevant data available. Materials to avoid No further relevant data available. Hazardous decomposition products No dangerous decomposition products 11. TOXICOLOGICAL INFORMATION Acute toxicity LD/LC50 values Serious eye damage/eye irritation Respiratory or skin sensitization Germ cell mutagenicity 5

SDS- Lysis Buffer Page 6 of 8 Skin corrosion/irritation Carcinogenicity No components of this product are listed by IARC, ACGIH, NTP and OSHA. Reproductive toxicity Teratogenicity Aspiration hazard Synergistic effects 12. ECOLOGICAL INFORMATION Toxicity Persistence and degradability Bioaccumulative potential Mobility in soil PBT and vpvb assessment Other adverse effects 6

SDS- Lysis Buffer Page 7 of 8 13. DISPOSAL CONSIDERATIONS Product Dispose of unused product, residues, and containers according to local, regional, state, and national regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods 15. REGULATORY INFORMATION OSHA Hazards No known OSHA hazards. SARA 302 Components SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the reporting levels established by SARA Title III, Section 313. SARA 311/312Hazards No SARA Hazards. 7

SDS- Lysis Buffer Page 8 of 8 16. OTHER INFORMATION For educational use only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRANTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE. 8

SDS- Flash Blue TM DNA Stain Page 1 of 8 1121 5 th Street NW Washington, DC 20001 www.edvotek.com Safety Data Sheet Version 2 Revision Date 08/09/2013 1. PRODUCT AND COMPANY IDENTIFICATION Product name: Flash Blue TM DNA Stain Product Number: 609 Brand: Supplier: Edvotek Edvotek 1121 5 th Street NW Washington, DC 20001 Telephone: 1-800-338-6835 or 202-370-1500 Fax: 202-370-1501 Emergency Phone # (For both supplier and Manufacturer): 202-370-1500 2. HAZARDS IDENTIFICATION Emergency Overview OSHA Hazards: Skin Irritant 2 Eye Irritant 2 Signal Word Warning Pictogram Hazard Statements H315 - Causes skin irritation H319 - Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P280 - Wear protective gloves/protective clothing/eye protection/face protection P302+ P352 - IF ON SKIN: Wash with plenty of soap and water P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a

SDS- Flash Blue TM DNA Stain Page 2 of 8 position comfortable for breathing. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing HMIS Classification: Health hazard: 2 Flammability: 0 Physical hazard: 0 NFPA Rating: Health hazard: 2 Reactivity Hazard: 0 Fire: 0 Potential Health Effects: Inhalation: May be harmful if inhaled. Causes respiratory tract irritation. Skin: Harmful if absorbed through skin. Causes skin irritation. Eyes: Causes eye irritation. Ingestion: Harmful if swallowed. 3. COMPOSITION/INFORMATION ON INGREDIENTS Synonyms: 3,7-Bis(dimethylamino) phenazathionium chloride 3,7-Bis(dimethylamino) phenothiazin-5-ium chloride Formula: C 16 H 18 ClN 3 S Molecular Weight: 319.85 g/mol Chemical name EC No. CAS No Concentration 3,7- Bis(dimethylamino) phenazathionium chloride 200-515-2 61-73-4

SDS- Flash Blue TM DNA Stain Page 3 of 8 4. FIRST AID MEASURES If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult doctor in case of complaints. In case of skin contact Immediately wash off with soap and plenty of water. Get medical attention if symptoms develop. In case of eye contact Flush eyes with water as a precaution. Get medical attention immediately if irritation persists. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Get medical attention if symptoms develop. 5. FIREFIGHTING MEASURES Conditions of flammability Not flammable or combustible. Suitable extinguishing media Use water spray, alcohol resistant foam, dry chemical or carbon dioxide. Special protective equipment for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Hazardous combustion products May emit toxic and/or irritating fumes under fire conditions. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Prevent skin/eye contact. Use personal protective equipment as needed. Environmental precautions Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and materials for containment and cleaning up Clean up spills immediately. Use absorbent materials if needed and dispose into a chemical waste container.

SDS- Flash Blue TM DNA Stain Page 4 of 8 7. HANDLING AND STORAGE Precautions for safe handling Avoid contact with skin and eyes. Good laboratory technique should be used when handling. Conditions for safe storage Keep containers tightly closed in a dry, cool and well-ventilated place. Incompatible Products Strong oxidizing agents. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment Respiratory protection Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection Wear protective gloves. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Eye protection Avoid eye contact with this material. Wear chemical safety glasses with side shields or chemical safety goggles. Skin and body protection Use chemical gloves as needed. Use clean protective body covering clothing as needed to minimize contact with clothing and skin. Hygiene measures General industrial hygiene practice. Keep away from foodstuffs and beverages. Avoid contact with the eyes and skin. Do not eat, drink or smoke while working with products.

SDS- Flash Blue TM DNA Stain Page 5 of 8 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form liquid Colour Blue Odor No odor Safety data ph Melting point/freezing point Boiling point Flash point Ignition temperature Autoignition Temperature Lower explosion limit Upper explosion limit Vapour pressure Density (water=1) Water solubility Partition coefficient: n-octanol/water Relative vapour Density Odour Threshold Evaporation rate 10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions No further relevant data available Conditions to avoid No further relevant data available Materials to avoid No further relevant data available Hazardous decomposition products Carbon oxides. Nitrogen oxides (NOx). Sulfur oxides. Hydrogen chloride gas

SDS- Flash Blue TM DNA Stain Page 6 of 8 11. TOXICOLOGICAL INFORMATION Acute toxicity LD/LC50 values Serious eye damage/eye irritation Skin corrosion/irritation Reproductive toxicity Teratogenicity Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity No components of this product are listed by IARC, ACGIH, NTP and OSHA. Aspiration hazard Synergistic effects 12. ECOLOGICAL INFORMATION Toxicity Persistence and degradability Bioaccumulative potential Mobility in soil PBT and vpvb assessment Other adverse effects

SDS- Flash Blue TM DNA Stain Page 7 of 8 13. DISPOSAL CONSIDERATIONS Product Dispose of unused product, residues, and containers according to local, regional, state, and national regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods 15. REGULATORY INFORMATION OSHA Hazards No known OSHA hazards. OSHA Hazards Target Organ Effect, Harmful by ingestion, Irritant. SARA 302 Components No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SARA 311/312 Hazards Acute Health Hazard, Chronic Health Hazard.

SDS- Flash Blue TM DNA Stain Page 8 of 8 16. OTHER INFORMATION For educational use only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE.

SDS- Salt Packets Page 1 of 7 1121 5 th Street NW Washington, DC 20001 www.edvotek.com Safety Data Sheet Version 2 Revision Date 08/27/2014 1. PRODUCT AND COMPANY IDENTIFICATION Product name: Salt packets Product Number: - Brand: Edvotek Supplier: Edvotek 1121 5 th Street NW Washington, DC 20001 Telephone: 1-800-338-6835 or 202-370-1500 Fax: 202-370-1501 Emergency Phone #: 202-370-1500 2. HAZARDS IDENTIFICATION Emergency Overview OSHA Hazards: No known OSHA hazards. Not a dangerous substance or mixture according to the Globally Harmonized System (GHS). HMIS Classification: Health hazard: 0 Flammability: 0 Physical hazard: 0 NFPA Rating: Health hazard: 0 Fire: 0 Reactivity Hazard: 0 Potential Health Effects: Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion: May be harmful if swallowed.

SDS- Salt Packets Page 2 of 7 3. COMPOSITION/INFORMATION ON INGREDIENTS No ingredients are hazardous according to OSHA criteria. 4. FIRST AID MEASURES General information No special measures required. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult doctor in case of complaints. In case of skin contact Immediately wash off with soap and plenty of water. Get medical attention if symptoms develop. In case of eye contact Flush eyes with water as a precaution. Get medical attention immediately if irritation persists. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Get medical attention if symptoms develop. 5. FIREFIGHTING MEASURES Conditions of flammability Not flammable or combustible. Suitable extinguishing media Use water spray, alcohol resistant foam, dry chemical or carbon dioxide. Special protective equipment for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Hazardous combustion products No known products.

SDS- Salt Packets Page 3 of 7 6. ACCIDENTAL RELEASE MEASURES Personal precautions Prevent skin/eye contact. Use personal protective equipment as needed. Environmental precautions Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and materials for containment and cleaning up Clean up spills immediately. Use absorbent materials if needed and dispose into a chemical waste container. 7. HANDLING AND STORAGE Precautions for safe handling No special measures necessary. Good laboratory technique should be used when handling. Conditions for safe storage No special measures necessary. Store at room temperature. Incompatible Products No known products. 8. EXPOSURE CONTROLS/ PERSONAL PROTECTION Personal protective equipment Respiratory protection Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection Wear protective gloves. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.

SDS- Salt Packets Page 4 of 7 Eye protection Avoid eye contact with this material. Wear chemical safety goggles. Skin and body protection Use chemical gloves as needed. Use clean protective body covering clothing as needed to minimize contact with clothing and skin. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash and dry hands at the end of workday. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form powder Colour white Odor no data avilable Safety data ph Melting point/freezing point Boiling point Flash point Ignition temperature Autoignition Temperature Lower explosion limit Upper explosion limit Vapour pressure Density (water=1) Water solubility Partition coefficient: n-octanol/water Relative vapour Density Odour Threshold Evaporation rate

SDS- Salt Packets Page 5 of 7 10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions No further relevant data available. Conditions to avoid No further relevant data available. Materials to avoid No further relevant data available. Hazardous decomposition products No dangerous decomposition products known. 11. TOXICOLOGICAL INFORMATION Acute toxicity LD/LC50 values Serious eye damage/eye irritation Skin corrosion/irritation Reproductive toxicity Teratogenicity Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity No components of this product are listed by IARC, ACGIH, NTP and OSHA. Aspiration hazard Synergistic effects

SDS- Salt Packets Page 6 of 7 12. ECOLOGICAL INFORMATION Toxicity Persistence and degradability Bioaccumulative potential Mobility in soil PBT and vpvb assessment Other adverse effects 13. DISPOSAL CONSIDERATIONS Product Dispose of unused product, residues, and containers according to local, regional, state, and national regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods

SDS- Salt Packets Page 7 of 7 15. REGULATORY INFORMATION OSHA Hazards No known OSHA hazards SARA 302 Components SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the reporting levels established by SARA Title III, Section 313. SARA 311/312Hazards No SARA Hazards 16. OTHER INFORMATION For educational use only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRANTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE.

SDS- Sodium Chloride Solution Page 1 of 7 1121 5 th Street NW Washington, DC 20001 www.edvotek.com Safety Data Sheet Version 2 Revision Date 09/24/2013 1. PRODUCT AND COMPANY IDENTIFICATION Product name: Sodium Chloride Solution Product Number: Brand: Edvotek Supplier: Edvotek 1121 5 th Street NW Washington, DC 20001 Telephone: 1-800-338-6835 or 202-370-1500 Fax: 202-370-1501 Emergency Phone #: 202-370-1500 2. HAZARDS IDENTIFICATION Emergency Overview OSHA Hazards: No known OSHA hazards. Not a dangerous substance or mixture according to the Globally Harmonized System (GHS). HMIS Classification: Health hazard: 1 Flammability: 0 Physical hazard: 0 NFPA Rating: Health hazard: 1 Fire: 0 Reactivity Hazard: 0 Potential Health Effects: Inhalation: May be harmful if inhaled. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion May be harmful if swallowed.

SDS- Sodium Chloride Solution Page 2 of 7 3. COMPOSITION/INFORMATION ON INGREDIENTS Formula: NaCl Molecular weight: 58.44 g/mol No ingredients are hazardous according to OHSA criteria. 4. FIRST AID MEASURES General information No special measures required. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult doctor in case of complaints. In case of skin contact Immediately wash off with soap and plenty of water. Get medical attention if symptoms develop. In case of eye contact Flush eyes with water as a precaution. Get medical attention immediately if irritation persists. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Get medical attention if symptoms develop. 5. FIREFIGHTING MEASURES Conditions of flammability Not flammable or combustible. Suitable extinguishing media Use water spray, alcohol resistant foam, dry chemical or carbon dioxide. Special protective equipment for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Hazardous combustion products Hydrogen chloride gas, Sodium oxides.

SDS- Sodium Chloride Solution Page 3 of 7 6. ACCIDENTAL RELEASE MEASURES Personal precautions Prevent skin/eye contact. Use personal protective equipment as needed. Environmental precautions Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and materials for containment and cleaning up Clean up spills immediately. Use absorbent materials if needed and dispose into a chemical waste container. 7. HANDLING AND STORAGE Precautions for safe handling No special measures necessary. Good laboratory technique should be used when handling. Conditions for safe storage No special measures necessary. Store at room temperature. Incompatible Products No known products 8. EXPOSURE CONTROLS/ PERSONAL PROTECTION Personal protective equipment Respiratory protection Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

SDS- Sodium Chloride Solution Page 4 of 7 Hand protection Wear protective gloves. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Eye protection Avoid eye contact with this material. Wear chemical safety goggles. Skin and body protection Use chemical gloves as needed. Use clean protective body covering clothing as needed to minimize contact with clothing and skin. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash and dry hands at the end of workday. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form liquid Color colorless Odor Safety data ph Melting point/freezing point Boiling point Flash point Ignition temperature Autoignition Temperature Lower explosion limit Upper explosion limit Vapor pressure Density (water=1) Water solubility Partition coefficient: n-octanol/water Relative vapour Density Odour Threshold Evaporation rate

SDS- Sodium Chloride Solution Page 5 of 7 10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions No further relevant data available. Conditions to avoid No further relevant data available. Materials to avoid No further relevant data available. Hazardous decomposition products No dangerous decomposition products known. 11. TOXICOLOGICAL INFORMATION Acute toxicity LD/LC50 values Serious eye damage/eye irritation Skin corrosion/irritation Reproductive toxicity Teratogenicity Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity No components of this product are listed by IARC, ACGIH, NTP and OSHA. Aspiration hazard Synergistic effects

SDS- Sodium Chloride Solution Page 6 of 7 12. ECOLOGICAL INFORMATION Toxicity Persistence and degradability Bioaccumulative potential Mobility in soil PBT and vpvb assessment Other adverse effects 13. DISPOSAL CONSIDERATIONS Product Dispose of unused product, residues, and containers according to local, regional, state, and national regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods

SDS- Sodium Chloride Solution Page 7 of 7 15. REGULATORY INFORMATION OSHA Hazards No known OSHA hazards SARA 302 Components SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the reporting levels established by SARA Title III, Section 313. SARA 311/312Hazards No SARA Hazards. 16. OTHER INFORMATION For educational use only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRANTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE.

SDS- Tris Buffer Page 1 of 7 1121 5 th Street NW Washington, DC 20001 www.edvotek.com Safety Data Sheet Version 2 Revision Date 08/27/2014 1. PRODUCT AND COMPANY IDENTIFICATION Product name: Product Number: Brand: Supplier: Tris Buffer Edvotek Edvotek 1121 5 th Street NW Washington, DC 20001 Telephone: 1-800-338-6835 or 202-370-1500 Fax: 202-370-1501 Emergency Phone #: 202-370-1500 2. HAZARDS IDENTIFICATION Emergency Overview OSHA Hazards: No known OSHA hazards. Not a dangerous substance or mixture according to the Globally Harmonized System (GHS). HMIS Classification: Health hazard: 1 Flammability: 0 Physical hazard: 0 NFPA Rating: Health hazard: 0 Fire: 0 Reactivity Hazard: 0 Potential Health Effects: Inhalation: May be harmful if inhaled. Skin: May be harmful if absorbed through skin. May cause skin irritation. Eyes: May cause eye irritation. Ingestion May be harmful if swallowed. - 1

SDS- Tris Buffer Page 2 of 7 3. COMPOSITION/INFORMATION ON INGREDIENTS Mixture of the substances listed bellow with nonhazardous additions. Chemical name EC No. CAS No Concentration EDTA, disodium 205-358-3 6381-92-6 dihydrate Tris hydroxymethyl aminomethane 201-064-4 77-86-1 4. FIRST AID MEASURES General information No special measures required. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult doctor in case of complaints. In case of skin contact Immediately wash off with soap and plenty of water. Get medical attention if symptoms develop. In case of eye contact Flush eyes with water as a precaution. Get medical attention immediately if irritation persists. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Get medical attention if symptoms develop. 5. FIREFIGHTING MEASURES Conditions of flammability Not flammable or combustible. Suitable extinguishing media Use water spray, alcohol resistant foam, dry chemical or carbon dioxide. Special protective equipment for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Hazardous combustion products Carbon oxides, Nitrogen oxides (NOx).

SDS- Tris Buffer Page 3 of 7 6. ACCIDENTAL RELEASE MEASURES Personal precautions Prevent skin/eye contact. Use personal protective equipment as needed. Environmental precautions Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. Methods and materials for containment and cleaning up Clean up spills immediately. Use absorbent materials if needed and dispose into a chemical waste container. 7. HANDLING AND STORAGE Precautions for safe handling No special measures necessary. Good laboratory technique should be used when handling. Conditions for safe storage No special measures necessary. Store at room temperature. Incompatible Products Strong oxidizing agents. 8. EXPOSURE CONTROLS/ PERSONAL PROTECTION Personal protective equipment Respiratory protection Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection Wear protective gloves. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.

SDS- Tris Buffer Page 4 of 7 Eye protection Avoid eye contact with this material. Wear chemical safety goggles. Skin and body protection Use chemical gloves as needed. Use clean protective body covering clothing as needed to minimize contact with clothing and skin. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash and dry hands at the end of workday. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form liquid Color colorless Odor Safety data ph 6-8 Melting point/freezing point Boiling point 100 o C Flash point Ignition temperature Autoignition Temperature Lower explosion limit Upper explosion limit Vapor pressure Density (water=1) 1.020 Water solubility Partition coefficient: n-octanol/water Relative vapour Density Odour Threshold Evaporation rate

SDS- Tris Buffer Page 5 of 7 10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Possibility of hazardous reactions No further relevant data available. Conditions to avoid No further relevant data available. Materials to avoid No further relevant data available. Hazardous decomposition products No dangerous decomposition products known. 11. TOXICOLOGICAL INFORMATION Acute toxicity LD/LC50 values Serious eye damage/eye irritation Skin corrosion/irritation Reproductive toxicity Teratogenicity Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity No components of this product are listed by IARC, ACGIH, NTP and OSHA. Aspiration hazard Synergistic effects

SDS- Tris Buffer Page 6 of 7 12. ECOLOGICAL INFORMATION Toxicity Persistence and degradability Bioaccumulative potential Mobility in soil PBT and vpvb assessment Other adverse effects 13. DISPOSAL CONSIDERATIONS Product Dispose of unused product, residues, and containers according to local, regional, state, and national regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods

SDS- Tris Buffer Page 7 of 7 15. REGULATORY INFORMATION OSHA Hazards No known OSHA hazards SARA 302 Components SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the reporting levels established by SARA Title III, Section 313. SARA 311/312Hazards No SARA Hazards. 16. OTHER INFORMATION For educational use only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRANTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE.