CHROMIS 500 N - NHS Ester - F5G031N

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Page: 1/6 CHROMIS 500 N - NHS Ester - F5G031N SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier: Product name: CHROMIS 500 N - NHS Ester Product code: F5G031N Brand: Cyanagen Srl CAS#: None 1.2. Relevant identified uses of the substance or mixture and uses advised against: Identified uses: Laboratory chemicals, manufactures of substances. 1.3. Details of the supplier of the safety data sheet: Company: Cyanagen Srl Telephone/fax: +39 051-534063 E-mail address: info@cyanagen.it 1.4. Emergency telephone number: Emergency phone: +39 02-6610-1029 Poison Control Center Ospedale Niguarda Cà Granda Piazza Ospedale Maggiore, 3-20162 Milano (ITALY). SECTION 2: Hazards identification 2.1. Classification of the substance or mixture: Not dangerous substance according to GHS. This substance is not classified as dangerous according to Directive 67/548/EEC. 2.2. Label elements: The product does not need to be labeled in accordance with EC directives or respective national laws. 2.3. Other hazards: None. SECTION 3: Composition/information on ingredients 3.1. Substances: Synonyms: CHROMIS 500 N - NHS Ester Formula: C28H35BF2N6O4 Molecular weight: 568.42 g/mol 3.2. Mixtures: Component: CHROMIS 500 N - NHS Ester Concentration: 98% CAS#: None EC-No#: None MSDS Print Date: 9/3/2013 1/6

Page: 2/6 SECTION 4: First aid measures 4.1. Description of first aid measures: Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention if symptoms appear. Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Skin: Wash with soap and water. Get medical attention if irritation develops. Eyes: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. 4.2. Most important symptoms and effects, both acute and delayed: 4.3. Indication of any immediate medical attention and special treatment needed: SECTION 5: Firefighting measures 5.1. Extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2. Special hazards arising from the substance or mixture: Produces toxic fumes in case of fire. 5.3. Advice for firefighters: Wear self contained breathing apparatus for firefighting if necessary. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures: Avoid dust formation. Avoid bathing vapors, mist or gas. 6.2. Environmental precautions: No special environmental precaution required. 6.3. Methods and material for containment and cleaning up: Use appropriate protective equipment and methods to clean up spilled substances promptly. Absorb spill onto an appropriate material. Collect and dispose of all waste in accordance with applicable laws. 6.4. Reference to other sections: For disposal see section 13. SECTION 7: Handling and storage 7.1. Precautions for safe handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. MSDS Print Date: 9/3/2013 2/6

Page: 3/6 7.2. Conditions for safe storage, including any incompatibilities: Store in a tightly closed container under inert atmosphere. Moisture sensitive. Protect material from long-term exposure to light. Keep refrigerated at -20 C. 7.3. Specific end use(s): Refer to the Instructions for proper and intended use. Otherwise, contact supplier for specific applications. SECTION 8: Exposure controls/personal protection 8.1. Control parameters: Components with workplace control parameters. 8.2. Exposure controls: Engineering controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below exposure limits. Personal protection: Wear appropriate gloves, lab coat, dust respirator, safety glasses with sideshields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator. For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Personal protection in case of a large spill: Splash goggles, full suit, dust respirator, glove, a self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient, consult a specialist BEFORE handling this product. Exposure limit: No data available. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties: Physical state and appearance: Solid. Odor: No data available. Color: Orange. ph (1% soln/water): No data available. Boiling point: No data available. Melting point: No data available. Volatility: No data available. Flammability: No data available. Explosive properties: No data available. Viscosity: No data available. λ abs,max: 496 nm (CH3OH). λ em,max: 506 nm (CH3OH). ε: 88000 M -1 cm -1 (CH3OH). Solubility: Dichloromethane, methanol, DMSO, DMF, acetonitrile. Insoluble in water. MSDS Print Date: 9/3/2013 3/6

Page: 4/6 9.2. Other information: SECTION 10: Stability and reactivity 10.1. Reactivity: 10.2. Chemical stability: Stable under normal temperatures and pressures. 10.3. Possibility of hazardous reactions: 10.4. Conditions to avoid: Light. 10.5. Incompatible materials: Avoid strong oxidants. 10.6. Hazardous decomposition products: No dangerous decomposition products identified. SECTION 11: Toxicological information 11.1. Information on toxicological effects: Acute toxicity: No data available. Irritation and corrosion: No data available. Sensitisation: No data available. Chronic exposure: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Potential Health Effects: o Inhalation: May be harmful if inhaled. May cause respiratory tract irritation. o Skin: May be harmful if absorbed through skin. May cause skin irritation. o Eyes: May cause eye irritation. o Ingestion: May be harmful if swallowed. SECTION 12: Ecological information 12.1. Toxicity: 12.2. Persistence and degradability: 12.3. Bioaccumulative potential: MSDS Print Date: 9/3/2013 4/6

Page: 5/6 12.4. Mobility in soil: 12.5. Results of PBT and vpvb assessment: 12.6. Other adverse effects: SECTION 13: Disposal considerations 13.1. Waste treatment methods: Product: Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging: Dispose of as unused product. SECTION 14: Transport information 14.1. UN number: ADR/RID: IMDG: IATA: 14.2. UN proper shipping name: ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods 14.3. Transport hazard class(es): ADR/RID: IMDG: IATA: 14.4. Packing group: ADR/RID: IMDG: IATA: 14.5. Environmental hazards: ADR/RID: No IMDG Marine pollutant: No IATA: 14.6. Special precautions for user: SECTION 15: Regulatory information 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture: This product is classified as non-hazardous according to EU Directive 67/548/CE. 15.2. Chemical safety assessment: MSDS Print Date: 9/3/2013 5/6

Page: 6/6 SECTION 16: Other information Further information: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Cyanagen Srl shall not be held liable for any damage resulting from handling or from contact with the above product. See invoice or packing slip for additional terms and conditions of sale. MSDS Print Date: 9/3/2013 6/6