Uno mirovenilaor-3 Insruion manual UNO order nr.:... Cusomer order nr.:... Cusomer:... Delivery Dae:... Serial Numer:...
Conens ) Inroduion PAGE: 2 2) General desripion PAGE: 2 3) Insallaion PAGE: 3 4) Priniples of he UNO Miro Venilaor-3 PAGE: 4 5) Tehnial Speifiaions PAGE: 5 6) Warrany PAGE: 6 7) Cirle Sysem PAGE: 7 8) Figures I, II,III,IV,V and VI PAGE: 8 - Read and undersand his Insruion Manual for he UNO Miro Venilaor-3 prior o using he UNO Miro Venilaor-3. (=UMV) Serviing and repairs of he UMV-3 are only allowed y qualified personnel aeped y UNO. Upon reeiving he UNO Miro Venilaor-3, perform a visual and mehanial inspeion for onealed damages. If any damage is found, noify he arrier a one and ask for a wrien inspeion. Phoograph any damage and prepare a wrien reord. Failure o do so wihin 5 days may resul in loss of laim. For any quesions, please ona your loal agen or UNO Roesvassaal BV P.O. Box 5 NL 69 AA Zevenaar Tel. +3 36 52445 Fax. +3 36 523785 E-mail: info@unov.om UNO MICRO Venilaor-3, UMV are rademarks of UNO Roesvassaal BV. Manual UMV-3 / 29 / Page:
. Inroduion The UNO Miro Venilaor-3 (= UMV) is a mehanial venilaor uniquely designed for he use wih mie and ra for respiraory suppor or oally onrolled inhalaion anaeshesia. The UMV is a single uni ha an onrol he reahing frequeny, he volume, he minimum and he maximum pressure. The UMV has a flexile irle sysem wih CO2 asorion. The UMV needs a erain gas flow and pressure o funion properly. The fresh gas inle ue onneor wih ue should e onneed o a gas supply. 2. General desripion The UMV onsis of he following iems: 2. 3. 4. 5. 6. 7. 8.. 9... 2. 3. 4.. ON / OFF Swih. 7. Used- or exessive gas oule ue onneor wih ue. 2. Frequeny seing (25 22 / min). 8. Power supply AC inpu / DC oupu uni. 3. Volume Seing (+ -). 9. CO2 asoren onainer (empy on arrival). 4. Pressure meer.. filled CO2 asoren onainer - o replae iem 9 efore insalling UMV-3. 5. Pressure seing.. Volume indiaion window ( 24). 6. Fresh (anaeshei-) gas inle ue onneor wih ue. 2. exended flexile irle ue wih Male luer (3) onneion for inuaion-ue. 4,. Power ord (2 piees). IMPORTANT Before onneing he UMV- exhange he CO2 asoren oles (iems 9 & ). The power supply AC inpu / DC oupu uni an e used for AC inpu of o 24 V~ and 6/5 Hz. Keep he UMV away from waer, do no dump i in waer or expose i o rain or moisure. Use he UMV only for is purpose as is menioned in paragraph. UNO an no e held responsile for damages resuling from he use of he UMV for oher purposes han menioned in paragraph or from an inorre operaion of he UMV. Do no ry o open any par of he UMV or ry o ge meal or oher sujes ino he UMV. This may ause an eleri shok and will effe he guaranee on he UMV. For serviing and repair of he UMV ona UNO Roesvassaal BV or an auhorized UNO agen. Before reurning he UMV o UNO or is agen, an UNO servie/repair numer should e oained. Reurned unis wihou an UNO servie/repair numer will no e aeped. Serviing and repairs of he UMV are only allowed y qualified personnel aeped y UNO. All anaeshei vapors oming from he oule ue onneor (iem 7) or from he male-luer onneion (iem 3) should e exraed from he heare y an appropriae anaeshei gas savenging sysem. Use only speial anaeshei-uing. Manual UMV-3 / 29 / Page: 2
3. INSTALLATION a) Conne he power supply AC inpu / DC oupu uni (iem 4) o he power enry module (DC) (iem 8) of he UMV. ) Plae he UMW wih power supply AC/inpu / DC oupu uni on suh a plae ha he eleri ord an e onneed o he power supply AC inpu / DC oupu uni. ) Conne he ue of he fresh (anaeshei-) gas inle (iem 6) o a flowmeer/vaporizer uni (preferaly a flowmeer wih low-flow ues and a vaporizer suiale for low gas flows) hrough he onneion par of he vaporizer oule. d) Plae he ue of he used- or exessive gas oule ue onneor (iem 7) in an exhaus sysem in suh a way ha no under- or overpressure will e reaed in his gas oule ue. (indire of pressureless exhaus). If no speial exhaus sysem is availale, e sure ha he ue of he used- or exessive gas oule is plaed in suh a plae or posiion ha he exhaused anaeshei gas anno e inhaled y any person. e) I is reommended o have a silione es lung availale in whih an inuaion-ue an e plaed. Wih his es lung and insered inuaion-ue whih will e used for he arge animal, he volume and pressure an e (pre-) se a general levels for he arge animal aking also ino aoun he lung ouner pressure and exra high resisane resuling from he very small diameer of he inuaion-ue, or a erain P.E.E.P 2 seing. This would failiaes he seing/fine-uning of he UMV variales - during he iniial period using he UMV - for respiraory suppor or oally onrolled inhalaion anaeshei. If his opion is availale, onne he silione es lung (wih he insered inuaion-ue) o he male-luer onneion (iem 3), swih on he UMV, se he flowmeer a he required gasmix (O2 and/or Air) and flow levels and (pre-) se he volume, pressure and frequeny on he UMV for he arge animal. f. If he opion menioned in g- is no availale, han swih on he UMV, se he flowmeer a he required gasmix (O2 and/or Air wih or wihou N2O) and flow level a a raio and level required for he arge. g) Now he ue (inuaion- or raheoomy-) of he arge animal an e onneed o he male luer ue onneion (iem 3), and he vaporizer an e se a he required volume %. h) Adjus or se he volume, frequeny and pressure on he UMV o he level required for he animal. The CO2 asoren onainer should e filled wih CO2 asoren. To fill he CO2 asoren onainer, unsrew he onainer from he lid and fill i wih CO2 asoren. Plae he filled CO2 asoren onainer arefully over he meal ues oming from he lid and srew he glass onainer on o he lid. Be sure ha he filled CO2 asoren onainer is firmly losed o he lid; leakage will resul in pressure loss of he sysem in he irui and herefore inorre funioning of he UMV! A lile (high vauum) grease on he rim of he glass onainer is o e advised efore i is srewed on o he lid. As an opion availale from UNO 2 Posiive End Expiraion Pressure Manual UMV-3 / 29 / Page: 3
4. Priniples of he UNO Mirovenilaor-3 The onep of he UMV and he posiion of he UMV in a se-up wih flowmeer and vaporizer are given on page 7. The venilaion paern of he UMV is ased on he naural, sponaneous respiraory paern of mie and ra, i.e. a SINUS-form wihou a plaeau. The sinus-form venilaion paern prevens high peak pressure in he lungs of he arge animals, ofen seen wih valve operaed venilaors. The UMV produes a sinus-form pulse for he mehanial venilaion of he animal. The UMV is oh frequeny and volume onrolled, as well as minimum- and maximum pressure onrolled. The volume, pressure and frequeny seings are dependen on he arge animal and size of he arge animal, u also on size of he inuaion ue used! The UMV has he following haraerisis: # Tidal volume seing a he venilaor.ml - 24ml (wihou ouner pressure) # Volume wih ouner pressure and endoraheal inuaion ue 2.ml - 2ml # Frequeny 25-225 / min # Pressure seings (minimum and maximum) mar up # Exernal P.E.E.P. possile # Inspiraion o expiraion raio : (Sinus form) # irle sysem wih CO2 asorion yes In order o avoid any misundersanding, please oserve he following general remarks: Beause of he very small inernal diameer of he inuaion ue for ra and mie, he (pre-) se volume on he UMV may have no any relaion wih he idal volume of he animal. Apar from he animal s own airway pressure we fae a very high resisane eause of he very small inernal diameer of he inuaion ue used for ra and mie. Therefore he (pre-) se volume is no more (u also no less) han he gas volume delivered o he irle of he sysem. The same an e said aou he pressure. The maximum pressure as well as he minimum pressure is no more han he pressure readings in he irle of he sysem. The pressure indued in he lungs of mie and ra is differen from he pressure readings on he pressure meer of he UMV. The volume seing on he UMV is no he same as he idal volume of he animal eause of ouner pressure and high resisane resuling from he very small inernal diameer of he inuaion ue. 2 Depending on he size of he ue s inernal diameer. Manual UMV-3 / 29 / Page: 4
Following are some imporan underlying elemens relaed o he seing of he volume and pressure of he UMV.. In order o e ale o perform he praial / es seings, he UMV should e plaed in a seup wih flowmeer (and vaporizer). Furher a es lung (as an opion availale) wih he insered inuaion ue has o e onneed o he male luer onneion (iem 3). 2. Wih he pressure seing (iem 5) he mean pressure is eing (pre-) se. The mean pressure level (mar) an e (pre-) se or heked as follows: Se he gas flow of he flowmeer a he required oal oupu level (= L/min). This should e done preferaly wih ompressed air or as an alernaive O2. Do no mix his gas flow ye wih N2O or he anaeshei gas, as his will e hazardous o he user. A he given gas flow from he flowmeer, you an read on he pressure meer (in iem 4) he mean pressure se. A hange (= urn) of he pressure seing (iem 5) will resul in a hange of he mean pressure, whih an e seen on he pressure reader (in iem 4). As you may oserve on he pressure meer (in iem 4), he mean pressure an very easily e hanged a he required level. The mean pressure an e ompared wih he zero-ax of he sinus graph. 3. Wih he volume seing (iem 3), he volume an e (pre-) se. Inrease or derease he volume hrough urning of he volume seing (iem 3) o + or, while here is pressure on he UMV. The (pre-) se volume in he UMV an e seen hrough he volume indiaion window (iem ) as a numer ( 24). Swih he UMV on (iem ). You will noie ha he pulse produed, will move he needle of he pressure meer around he mean pressure, and also will hange he volume in he es lung! The volume an e se a any level eween and 24 (depending on he volume of he inuaion ue used) on he volume indiaion window (iem ). This volume seing an e ompared wih he ampliude of he sinus graph. 4. In order o (pre-) se a P.E.E.P, he volume seing (iem 3) should e urned o + unil he minimum pressure reading (on he pressure meer in iem 4) is > a he required mar level. If he new maximum pressure (on he pressure meer in iem 4) is oo high, redue he volume, and if neessary adjus he pressure again o pressure and volume levels you need! 5. Please noe again ha he levels of volume and pressure delivered o he animal are dependen on he used inuaion ue. Volume measuremen a he end of he inuaion ue in a mouse or ra is only done in speial es se-ups and is no a sandard feaure. 6. Venilaion and inhalaion anaeshesia of ra and mouse need a erain level of experiene and good oservaion of he animal. 7. The UMV is equipped wih a so-alled zero-valve, prevening pressure levels elow (i.e. negaive pressures) in he sysem. As also menioned under paragraph 3.d, he ue on he used- or exessive gas oule ue onneor (iem 7) has o e plaed in a gas-exhaus sysem in suh a way ha no under- or overpressure will e reaed in his gas oule ue. 8. The frequeny an e adjused hrough hanging (lokwise=+ or ani-lokwise=-) he frequeny seing (iem 2) o he required level. 9. In he figures I o VI a graphial expressions is given of volume-, pressure- and frequeny seings/adjusmens of he UMV. (See pages 8 o.) Manual UMV-3 / 29 / Page: 5
5. Tehnial Speifiaions The UMV has he following ehnial speifiaions: - Volage - 24 V a 5 Vd - Frequeny 6/5 Hz - Power ord deahale 3-wire ordse - Operaing emperaure range 5 o 35 C - Tidal volume seing a he,ml 24ml venilaor (wihou ouner pressure) - Venilaion Volume wih ouner,ml 2ml pressure and inuaion ue 2 - Venilaion Frequeny 25 225 / min - Pressure seing9 (min. and max.) mar up - Exernal P.E.E.P. possile - Inspiraion o expiraion raio : (Sinus Form) - Cirle sysem wih CO2 asorion yes 6. Warrany The UNO Miro Venilaor-3 is warraned free of defes in maerial and workmanship for a period of one () year. UNO dislaims all implied warranies. The volume seing on he UMV is no he same as he idal volume of he animal eause of ouner pressure and high resisane of resuling from he very small inernal diameer of he inuaion ue. 2 Depending on size of he ue s inernal diameer. Manual UMV-3 / 29 / Page: 6
Cirle-Sysem wih inhalaion aneshesia for oally onrolled venilaion for mouse and ra.. Adjusale volume wheel 2. Caron dioxide asorer 3. Underpressure valve 4. Overpressure valve 5. Gas pressure adjusmen 6. Conrole valves 7. Gas pressure measurer 8. Inuaion-ue onneion (Luer Lok) 9. Venilaion A. Flowmeer wih gas supplies of O2, N2O (and air) wih ue per gas for exra low flow adjusmen. B. Vaporizer for isoflurane or sevoflurane wih very aurae performane also a low flows, and fully emperaure ompensaed. C. Conep of he UNO Miro-Venilaor for Mouse/Ra venilaion. Adjusale for volume, frequeny and gas pressure wih a sinus-form venilaion paern. Manual UMV-3 / 29 / Page: 7
Figure I P(mar) a -max Figure I. Sinus-form venilaion paern wihou PEEP a : volume : mean pressure -max : maximum pressure : respiraion / venilaion yle Figure II P(mar) a -max Figure II. Sinus venilaion paern (wihou PEEP) wih inreased pressure a : volume : inreased mean pressure + -max : inreased maximum pressure+ : respiraion / venilaion yle Graphial expression of he volume -, pressure- and frequeny seings / adjusmens of he UNO Miro Venilaor : Manual UMV-3 / 29 / Page: 8
Figure III P(mar) a -max Figure IV Figure III. Sinus-form venilaion paern (wihou PEEP) wih inreased volume and inreased pressure a : volume + : inreased mean pressure + -max 3 : inreased maximum pressure +++ : respiraion / venilaion yle P(mar) a -max 2 2 x Figure IV. Sinus venilaion paern wih PEEP, inreased volume and inreased pressure a : volume 2 : inreased mean pressure ++ -max 2 : inreased maximum pressure++ : respiraion / venilaion yle x : PEEP Graphial expression of he volume -, pressure- and frequeny seings / adjusmens of he UNO Miro Venilaor : Manual UMV-3 / 29 / Page: 9
Figure V P(mar) a - -max 2 x Figure VI Figure V. Sinus-form venilaion paern (wihou PEEP) dereased volume and inreased pressure a - : dereased volume - 2 : inreased mean pressure ++ -max : inreased maximum pressure + : respiraion / venilaion yle x : inreased PEEP+ P(mar) a -max Figure VI. Sinus venilaion paern wihou PEEP wih inreased pressure a : volume : mean pressure -max : maximum pressure : respiraion / venilaion yle+ Remarks: The inrease (derease) of volume on he sale of he UNO Miro Venilaor resuls in an inrease (derease) of he ampliude of he sinus-urve. Furher he inreased (dereased) ampliude of he sinus-urve also implies an inrease (dereasse) of he min./max. pressure. The inrease (derease) of pressure on he sale of he UNO Miro Venilaor resuls in an inrease (derease) of he mean pressure. A Zero -pressure valve is uil ino he sysem in order o preven negaive pressure. This an also e oserved in he graphis; he pressure urve (=solid line) is never elow. Manual UMV-3 / 29 / Page: