Zhang Xuezhen Ph.D. Curriculum Vitae. Zhang Xuezhen Ph.D

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Curriculum Vitae Zhang Xuezhen Ph.D Family Name: Zhang Given Name: Xuezhen Date of Birth: Sep.4, 1974 Place of Birth: Linyi, China Citizenship: Chinese Working telephone: +86-27-87282113 Working Fax: +86-27-87282114 Professional address: College of Fisheries, Huazhong Agricultural University Wuhan, 430070 P.R.China E-mail: xuezhen@mail.hzau.edu.cn zhangxuezhen78@gmail.com ACADAMIC RANK AND POSITION 2009-Present Associate professor in aquaculture and aquatic toxicology, College of Fisheries, Huazhong Agricultural University 2004-2009 Lecturer in aquaculture, College of Fisheries, Huazhong Agricultural University EDUCATION 2010-2011 Sichuan International Studies University (SISU) Advanced English Training Program 2005-2008 College of Fisheries, Huazhong Agricultural University Ph.D. in Aquaculture Thesis titled Comparative research on the toxic effects of microcystins to fish and mammal Page 1 of 5

2000-2003 College of Fisheries, Huazhong Agricultural University MA.Sci. in Aquaculture Thesis titled Studies on intensive rearing of fries of large-mouth catfish, Silurus Soldatovi Meridionalis (Chen) in fixed bed biofilter purgative close recirculation system 1995-1999 College of Fisheries, Huazhong Agricultural University BA. in Aquaculture Thesis titled Quantification analysis on morphology of southern catfish PROFESSIONAL EXPERIENCE 1999-Present Work for the College of Fisheries, Huazhong Agricultural University Teaching Teaching Zoology and Zoological Experiment for undergraduates. Teaching Animal Physiology Experiment for undergraduates. Teaching Advances in Fisheries Science for graduates Research Research on toxic effects of cyanobacterial bloom and microcystins on fish and mammal Research on toxic effects of microcysitns on embryonic development of southern catfish Research on transcriptional changes of apoptosis related gene in zebrafish exposed to microcystins Research on effects of temperature on HSPs, CYPs, GSTs gene transcription Research on the skills in artificial spawning of southern cat fish HONORS AND AWARDS The Award for The Best Doctoral Dissertation of China Project supported by the National Science Foundation for Distinguished Young Scholars of Hubei Province Page 2 of 5

Ten Outstanding Youth Post Expert of Huazhong Agricultural University The Award for The Best Guidance on Undergraduate Science and Technology Innovation of Huazhong Agricultural University REASEARCH FILEDS Environmental biology of fishes: in particular research into the effect of organic and chemical compounds (such as algae toxins and pesticides) and natural environmental factors (such as photoperiod and temperature) on development, growth, behavior, antioxidant system, reproduction and related gene expressions of fishes. Aquatic toxicology: mainly focused on toxic mechanism of cyanobacterial bloom and microcystins on embryonic development, hematological parameters, transcriptional alterations of related gene and protein expression. Aquaculture: southern catfish culture, study on the patterns of pond culture, breeding skills, and artificial reproduction. Investigation of fish resources of lakes. EXPERIMENTAL TECHNIQUES Excellent skills in fish breeding, fish surgery, artificial spawning Familiar with the methodology of ecology, toxicology, and molecular biology. RESEARCH GRANTS AWARDED National Natural Science Foundation of China (2009-2011) Project supported by the National Science Foundation for Distinguished Young Scholars of Hubei Province Page 3 of 5

SELECTED ARTICALES 1. Zhang, X., Xie, P., Li, D., Shi, Z., 2007. Haematological and plasma biochemical responses of crucian carp (Carassius auratus) to intraperitoneal injection of extracted microcystins with the possible mechanisms of anemia. Toxicon. 49, 1150-1157. 2. Zhang, X., Xie, P., Wang, W., Li, D., Li, L., Tang, R., Lei, H., Shi, Z., 2008. Dose dependent effects of extracted microcystins on embryonic development, larval growth and histopathological changes of southern catfish Silurus meridionalis. Toxicon. 51, 449-456. 3. Zhang, X., Xie, P., Wang, W., Li, D., Shi, Z., 2008. Plasma biochemical responses of the omnivorous crucain carp Carassius auratus to crude cyanobacterial extracts. Fish Physiol Biochem. 34, 323 329. 4. Zhang, X., Xie, P., Li, D., Tang, R., Lei, H., Zhao, Y., 2009. Time-dependent oxidative stress responses of crucian carp (Carassius auratus) to intraperitoneal injection of extracted microcystins. Bull Environ Contam Toxicol, 82:574 578. 5. Zhang, X., Li, D. 2009. Effects of microcystins on some physiological and biochemical parameters of blood in rabbit. Journal of Huazhong Agricultural Universiy. 28, 183-187. (in Chinese) 6. Liang, H., Zhang, X., ( ), Liang, Y. 2009. Threatened fishes of the world: Leptobotia elongata (Bleeker, 1870) (Botiidae) Enoviron. Biol. Fish. 85, 287-288. 7. Zhang, X.,( ), Li, D.2009. Threatened fishes of the world: Acipenser schrenckii Brandt, 1869 (Acipenseridae). Enoviron. Biol. Fish. 85, 187. 8. Zhang, X., Xie, P., Ji, W., Zhang, H., Zhang, W. 2011. Studies on the toxic effects of microcystin-lr on the zebrafish (Danio rerio) under different temperatures. J. Appl. Toxicol. 31, 561 567. 9. Zhang, X., Xie, P., Li, D., Shi, Z., Wang, J., Yuan, G., Zhao,Y., Tang, R.2011. Anemia induced by repeated exposure to cyanobacterial extracts with explorations of underlying mechanisms. Environ. Toxicol. 26, 472-9. 10. Li, D., Xie, P., Zhang, X. 2008. Changes in plasma thyroid hormones and cortisol levels in crucian carp (Carassius auratus) exposed to the extracted microcystins. Chemosphere 74, 13 18. 11. Zhao, Y., Xie, P., Zhang, X. 2009. Oxidative stress response after prolonged exposure of domestic rabbit to a lower dosage of extracted microcystins. Environ Page 4 of 5

Toxicol Phar. 27,195-199. 12. Li, D., Xie, P., Zhang, X., Zhao, Y. 2009. Intraperitoneal injection of extracted microcystins results in hypovolemia and hypotension in crucian carp (Carassius auratus). Toxicon. 53,638-644. 13. Zhao, Y., Xie, P., Tang, R., Zhang, X., Li, L., Li, D. 2008. In vivo studies on the toxic effects of microcystins on mitochondrial electron transport chain and ion regulation in liver and heart of rabbit. Comp. Biochem. Phys, Part C 148, 204 210. 14. Sun, Y., Tang, R., Li, D., Zhang, X., Fu, J., Xie, P. 2008. Acute effects of microcystins on the transcription of antioxidant enzyme genes in crucian carp Carassius auratus. Environ Toxicol. 23,145-152. 15. Lei, H., Xie, P., Chen, J., Liang, G., Dai, D., Zhang, X. 2008. Distribution of toxins in blood, heart, gill, liver, gallbladder, intestine, spleen, gonad, brain and kidney of the ominivorous crucian carp intraperitoneally injected with hepatotoxic microcystins. Environ Toxicol Chem. 27, 1167 1174. 16. Li, G., Chen, J., Xie, P., Jiang, Y., Wu, L., Zhang, X. 2011. Protein profiles in zebrafish (Danio rerio) embryos exposed to microcystin-lr. Proteomics11, 2003-2018. Page 5 of 5