MATERIAL SAFETY DATA SHEET 1. Product and Company Identification Material name Version # 02 Polysorbate 20 NF Revision date 08-30-2011 CAS # 9005-64-5 Product Codes J.T.Baker: 4116, 4600 Synonym(s) Polyoxyethylene sorbitan monolaurate; Polysorbate 20 Manufacturer Address Customer Service 855-282-6867 24 Hour Emergency 908-859-2151 Chemtrec 800-424-9300 Avantor Performance Materials, Inc. 3477 Corporate Parkway Suite #200 Center Valley, PA 18034 US 2. Hazards Identification Emergency overview OSHA regulatory status Potential health effects Routes of exposure Eyes Skin Inhalation Ingestion Signs and symptoms CAUTION This product is considered hazardous under 29 CFR 1910.1200 (Hazard Communication). Skin contact. Eye contact. Inhalation. Ingestion. Contact with eyes may cause irritation. Avoid contact with eyes. May cause skin irritation. Avoid contact with the skin. May cause inhalation hypersensitivity (occupational asthma) in sensitive individuals. Difficulty in breathing. Avoid breathing dust/fume/gas/mist/vapors/spray. Ingestion of this product may cause nausea, vomiting and diarrhea. Symptoms may include redness, edema, drying, defatting and cracking of the skin. Shortness of breath. 3. Composition / Information on Ingredients Components CAS # Percent Polysorbate 20 NF 9005-64-5 100 4. First Aid Measures First aid procedures Eye contact Skin contact Inhalation Ingestion General advice Immediately flush eyes with plenty of water for at least 15 minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention if irritation develops and persists. Take off contaminated clothing and wash before reuse. Rinse skin with water/shower. Get medical attention if irritation develops and persists. If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Call a physician if symptoms develop or persist. If ingestion of a large amount does occur, call a poison control center immediately. Do not induce vomiting without advice from poison control center. Rinse mouth thoroughly. If you feel unwell, seek medical advice (show the label where possible). Show this safety data sheet to the doctor in attendance. 1 / 5
5. Fire Fighting Measures Flammable properties Extinguishing media Suitable extinguishing media Protection of firefighters Protective equipment and precautions for firefighters Special protective equipment for fire-fighters t flammable by OSHA criteria. Water. Use any media suitable for the surrounding fires. Move containers from fire area if you can do so without risk. Cool containers exposed to flames with water until well after the fire is out. As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. 6. Accidental Release Measures Personal precautions Environmental precautions Methods for containment Methods for cleaning up Ensure adequate ventilation. Keep unnecessary personnel away. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Prevent further leakage or spillage if safe to do so. Do not contaminate water. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Stop the flow of material, if this is without risk. Prevent entry into waterways, sewer, basements or confined areas. Should not be released into the environment. Large Spills: Stop the flow of material, if this is without risk. Absorb in vermiculite, dry sand or earth and place into containers. Following product recovery, flush area with water. Small Spills: Wipe up with absorbent material (e.g. cloth, fleece). Clean surface thoroughly to remove residual contamination. Other information 7. Handling and Storage Handling Storage Never return spills in original containers for re-use. For waste disposal, see section 13 of the MSDS. Clean up in accordance with all applicable regulations. DO NOT handle, store or open near an open flame, sources of heat or sources of ignition. Protect material from direct sunlight. Do not use in areas without adequate ventilation. Avoid contact with skin and eyes. Avoid breathing mist or vapor. Wear personal protective equipment. Wash thoroughly after handling. Use care in handling/storage. Avoid release to the environment. Keep containers tightly closed in a dry, cool and well-ventilated place. Protect from light. Keep away from heat, sparks and open flame. Store in a closed container away from incompatible materials. Store in accordance with local/regional/national/international regulation. 8. Exposure Controls / Personal Protection Engineering controls Personal protective equipment Eye / face protection Skin protection Respiratory protection General hygeine considerations 9. Physical & Chemical Properties Appearance Color Odor Provide adequate general and local exhaust ventilation. Chemical goggles are recommended. Wear appropriate chemical resistant clothing. Chemical resistant gloves. protection is ordinarily required under normal conditions of use and with adequate ventilation. Provide eyewash station and safety shower. Avoid contact with eyes. Avoid contact with skin. When using, do not eat, drink or smoke. Wash hands before breaks and immediately after handling the product. Handle in accordance with good industrial hygiene and safety practice. Clear. Amber. 2 / 5
Odor threshold Physical state Form ph Melting point Freezing point Boiling point Flash point Evaporation rate Flammability limits in air, upper, % by volume Flammability limits in air, lower, % by volume Vapor density Liquid. Liquid. Specific gravity 1.11 Relative density Solubility (water) Partition coefficient (n-octanol/water) Auto-ignition temperature Decomposition temperature > 212 F (> 100 C) 298.4 F (148 C) Pensky-Martens Closed Cup t available 10. Chemical Stability & Reactivity Information Chemical stability Conditions to avoid Incompatible materials Hazardous decomposition products Possibility of hazardous reactions 11. Toxicological Information Sensitization Local effects Carcinogenicity Epidemiology Mutagenicity Reproductive effects Material is stable under normal conditions. Heat, flames and sparks. Oxidizing agents. Light. Carbon oxides. Hazardous polymerization does not occur. t classified. This product is not considered to be a carcinogen by IARC, ACGIH, NTP, or OSHA. epidemiological data is available for this product. data available to indicate product or any components present at greater than 0.1% are mutagenic or genotoxic. Classification not possible. Classification not possible. 12. Ecological Information Ecotoxicity Environmental effects Aquatic toxicity Persistence and degradability Partition coefficient (n-octanol/water) The product components are not classified as environmentally hazardous. However, this does not exclude the possibility that large or frequent spills can have a harmful or damaging effect on the environment. An environmental hazard cannot be excluded in the event of unprofessional handling or disposal. Classification not possible. data is available on the degradability of this product. t available 3 / 5
13. Disposal Considerations Disposal instructions Contaminated packaging 14. Transport Information DOT IATA IMDG This product, in its present state, when discarded or disposed of, is not a hazardous waste according to Federal regulations (40 CFR 261.4 (b)(4)). Under RCRA, it is the responsibility of the user of the product to determine, at the time of disposal, whether the product meets RCRA criteria for hazardous waste. Empty containers should be taken to an approved waste handling site for recycling or disposal. 15. Regulatory Information US federal regulations This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200. All components are on the U.S. EPA TSCA Inventory List. CERCLA (Superfund) reportable quantity ne CERCLA/SARA Hazardous Substances - t applicable. Superfund Amendments and Reauthorization Act of 1986 (SARA) Hazard categories Immediate Hazard - Delayed Hazard - Fire Hazard - Pressure Hazard - Reactivity Hazard - Section 311 hazardous chemical Inventory status Country(s) or region Australia Canada Canada China Europe Europe Japan Korea New Zealand Philippines United States & Puerto Rico Inventory name Australian Inventory of Chemical Substances (AICS) Domestic Substances List (DSL) n-domestic Substances List (NDSL) Inventory of Existing Chemical Substances in China (IECSC) European Inventory of Existing Commercial Chemical Substances (EINECS) European List of tified Chemical Substances (ELINCS) Inventory of Existing and New Chemical Substances (ENCS) Existing Chemicals List (ECL) New Zealand Inventory Philippine Inventory of Chemicals and Chemical Substances (PICCS) Toxic Substances Control Act (TSCA) Inventory On inventory (yes yes/no no)* *A "" indicates that all components of this product comply with the inventory requirements administered by the governing country(s) State regulations This product does not contain a chemical known to the State of California to cause cancer, birth defects or other reproductive harm. 4 / 5
Saf-T-Data 16. Labeling Info Label Hazard Warning Label Precautions Label First Aid Health: 1 - Slight Flammability: 1 - Slight Reactivity: 0 - ne Contact: 1 - Slight Lab Protective Equip: C - GOGGLES; LAB COAT; PROPER GLOVES Storage Color Code: G - Green (General Storage) CAUTION Avoid contact with eyes, skin, and clothing. Keep container closed. Wash thoroughly after handling. Immediately flush eyes with plenty of water for at least 15 minutes. Flush skin thoroughly with water. If gas/fume/vapor/dust/mist from the material is inhaled, remove the affected person immediately to fresh air. Get medical attention if irritation develops or persists. If ingestion of a large amount does occur, call a poison control center immediately. Do not induce vomiting without advice from poison control center. If vomiting occurs, keep head low so that stomach content doesn't get into the lungs. 17. Other Information NFPA ratings Health: 2 Flammability: 1 Instability: 0 Disclaimer Issue date 08-30-2011 THE INFORMATION PRESENTED IN THIS MATERIAL SAFETY DATA SHEET (MSDS/SDS) WAS PREPARED BY TECHNICAL PERSONNEL BASED ON DATA THAT THEY BELIEVE IN THEIR GOOD FAITH JUDGMENT IS ACCURATE. HOWEVER, THE INFORMATION PROVIDED HEREIN IS PROVIDED AS IS, AND AVANTOR PERFORMANCE MATERIALS MAKES AND GIVES NO REPRESENTATIONS OR WARRANTIES WHATSOEVER, AND EXPRESSLY DISCLAIMS ALL WARRANTIES REGARDING SUCH INFORMATION AND THE PRODUCT TO WHICH IT RELATES, WHETHER EXPRESS, IMPLIED, OR STATUTORY, INCLUDING WITHOUT LIMITATION, WARRANTIES OF ACCURACY, COMPLETENESS, MERCHANTABILITY, NON-INFRINGEMENT, PERFORMANCE, SAFETY, SUITABILITY, STABILITY, AND FITNESS FOR A PARTICULAR PURPOSE, AND ANY WARRANTIES ARISING FROM COURSE OF DEALING, COURSE OF PERFORMANCE, OR USAGE OF TRADE. THIS MSDS/SDS IS INTENDED ONLY AS A GUIDE TO THE APPROPRIATE PRECAUTIONARY HANDLING OF THE MATERIAL BY A PROPERLY TRAINED PERSON USING THIS PRODUCT, AND IS NOT INTENDED TO BE COMPREHENSIVE AS TO THE MANNER AND CONDITIONS OF USE, HANDLING, STORAGE, OR DISPOSAL OF THE PRODUCT. INDIVIDUALS RECEIVING THIS MSDS/SDS MUST ALWAYS EXERCISE THEIR OWN INDEPENDENT JUDGMENT IN DETERMINING THE APPROPRIATENESS OF SUCH ISSUES. ACCORDINGLY, AVANTOR PERFORMANCE MATERIALS ASSUMES NO LIABILITY WHATSOEVER FOR THE USE OF OR RELIANCE UPON THIS INFORMATION. NO SUGGESTIONS FOR USE ARE INTENDED AS, AND NOTHING HEREIN SHALL BE CONSTRUED AS, A RECOMMENDATION TO INFRINGE ANY EXISTING PATENTS OR TO VIOLATE ANY FEDERAL, STATE, LOCAL, OR FOREIGN LAWS. AVANTOR PERFORMANCE MATERIALS REMINDS YOU THAT IT IS YOUR LEGAL DUTY TO MAKE ALL INFORMATION IN THIS MSDS/SDS AVAILABLE TO YOUR EMPLOYEES. 5 / 5