Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium Acros Organics Company Identification: (USA)

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Material Safety Data Sheet Celite Section 1 - Chemical Product and Company Identification MSDS Name: Celite Catalog Numbers: 17346-0000, 17346-0100, 17346-0250 Synonyms: Infusorial earth; Diatomite; Diatomaceous earth Acros Organics BVBA Company Identification: Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium Acros Organics Company Identification: (USA) One Reagent Lane Fair Lawn, NJ 07410 For information in the US, call: 800-ACROS-01 For information in Europe, call: +32 14 57 52 11 Emergency Number, Europe: +32 14 57 52 99 Emergency Number US: 201-796-7100 CHEMTREC Phone Number, US: 800-424-9300 CHEMTREC Phone Number, Europe: 703-527-3887 Hazard Symbols: Section 2 - Composition, Information on Ingredients CAS# Chemical Name: % EINECS# 61790-53-2 Celite unlisted XN Risk Phrases: 36/37 48/20 Section 3 - Hazards Identification EMERGENCY OVERVIEW Irritating to eyes and respiratory system. Harmful : danger of serious damage to health by prolonged exposure through inhalation. Potential Health Effects Eye: Skin: Dust may cause mechanical irritation. May cause skin irritation.

Ingestion: May cause irritation of the digestive tract. Causes respiratory tract irritation. Contains crystalline silica which may lead to Inhalation: respiratory abnormalities and silicosis. Chronic: Chronic exposure may cause lung damage. Eyes: Skin: Ingestion: Inhalation: Notes to Physician: General Information: Extinguishing Media: General Information: Spills/Leaks: Section 4 - First Aid Measures Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Flush skin with plenty of soap and water. Get medical aid. Wash mouth out with water. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Section 5 - Fire Fighting Measures As in any fire, wear a self-contained breathing apparatus in pressuredemand, MSHA/NIOSH (approved or equivalent), and full protective gear. Substance is noncombustible. Use agent most appropriate to extinguish fire. Section 6 - Accidental Release Measures Use proper personal protective equipment as indicated in Section 8. Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Section 7 - Handling and Storage Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and Handling: clothing. Avoid ingestion and inhalation. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 61790-53-2: United Kingdom, WEL - TWA: 1.2 mg/m3 TWA (respirable dust) United Kingdom, WEL - STEL: 3.6 mg/m3 STEL (respirable dust)

Belgium - TWA: 3 mg/m3 VLE (respirable fraction); 10 mg/m3 VLE (inhalable fraction) Germany: 4 mg/m3 TWA (inhalable fraction) Malaysia: 10 mg/m3 TWA (particulate matter containing no asbestos and <1% crystalline sili Russia: 3 mg/m3 STEL (total aerosol) Spain: 10 mg/m3 VLA-ED (inhalable fraction, this value is for the particulated matter t Personal Protective Equipment Eyes: Wear chemical splash goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 Respirators: approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - Physical and Chemical Properties Physical State: Powder Color: white - grey - pink Odor: Not available ph: Not available Vapor Pressure: Not available Viscosity: Not available Boiling Point: Not available Freezing/Melting Point: Not available Autoignition Temperature: Not available Flash Point: Not available Explosion Limits: Lower: Not available Explosion Limits: Upper: Not available Decomposition Temperature: Not available Solubility in water: Insoluble Specific Gravity/Density: Molecular Formula: O2Si Molecular Weight: 60.08

Chemical Stability: Conditions to Avoid: Incompatibilities with Other Materials Hazardous Decomposition Products Hazardous Polymerization RTECS#: Section 10 - Stability and Reactivity Stable under normal temperatures and pressures. Incompatible materials, moisture. Strong oxidizing agents, strong acids. Oxides of silicon. Has not been reported. Section 11 - Toxicological Information CAS# 61790-53-2: VV7311000 LD50/LC50: RTECS: Not available. Celite - IARC: Group 3 (not classifiable) Carcinogenicity: Other: Not available The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information. Section 12 - Ecological Information Section 13 - Disposal Considerations Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - Transport Information IATA IMO RID/ADR Shipping Name: Not regulated. Not regulated. Not regulated. Hazard Class: UN Number: Packing Group: European/International Regulations Section 15 - Regulatory Information European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 36/37 Irritating to eyes and respiratory system. R 48/20 Harmful : danger of serious damage to health by prolonged exposure through inhalation. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 39 Wear eye/face protection. WGK (Water Danger/Protection)

CAS# 61790-53-2: Not available Canada CAS# 61790-53-2 is listed on Canada's NDSL List </ TD> US Federal TSCA CAS# 61790-53-2 is listed on the TSCA Inventory. Section 16 - Other Information MSDS Creation Date: 7/16/1996 Revision #1 Date 6/06/2005 Revisions were made in Sections: General revision. The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantibility or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential, or exemplary damages howsoever arising, even if the company has been advised of the possibility of such damages. --------------------------------------------------------------------------------