Section 1 - Chemical Product and Company Identification MSDS Name: Azelaic acid, 98% Catalog Numbers: , ,

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Material Safety Data Sheet Azelaic acid, 98% Section 1 - Chemical Product and Company Identification MSDS Name: Azelaic acid, 98% Catalog Numbers: 40152-0000, 40152-0250, 40152-1000 Synonyms: Nonanedioic acid Acros Organics BVBA Company Identification: Janssen Pharmaceuticalaan 3a 2440 Geel, Belgium Acros Organics Company Identification: (USA) One Reagent Lane Fair Lawn, NJ 07410 For information in the US, call: 800-ACROS-01 For information in Europe, call: +32 14 57 52 11 Emergency Number, Europe: +32 14 57 52 99 Emergency Number US: 201-796-7100 CHEMTREC Phone Number, US: 800-424-9300 CHEMTREC Phone Number, Europe: 703-527-3887 Hazard Symbols: Risk Phrases: Potential Health Effects Section 2 - Composition, Information on Ingredients CAS# Chemical Name: % EINECS# 123-99-9 Azelaic acid 98% 204-669-1 None listed None listed Section 3 - Hazards Identification EMERGENCY OVERVIEW Not available Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Section 4 - First Aid Measures

Eyes: Skin: Ingestion: Inhalation: Notes to Physician: General Information: Extinguishing Media: General Information: Spills/Leaks: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid. Wash mouth out with water. Remove from exposure and move to fresh air immediately. Treat symptomatically and supportively. Section 5 - Fire Fighting Measures As in any fire, wear a self-contained breathing apparatus in pressuredemand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - Accidental Release Measures Use proper personal protective equipment as indicated in Section 8. Vacuum or sweep up material and place into a suitable disposal container. Section 7 - Handling and Storage Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 123-99-9: Personal Protective Equipment Eyes: Wear chemical splash goggles.

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 Respirators: approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - Physical and Chemical Properties Physical State: Crystalline powder Color: white to light yellow Odor: fatty acid odor ph: Not available Vapor Pressure: <1hPa @20 deg C Viscosity: Not available Boiling Point: 237 deg C @20hPa ( 458.60 F) Freezing/Melting Point: 98-103 deg C Autoignition Temperature: Not available Flash Point: 215 deg C ( 419.00 deg F) Explosion Limits: Lower: Not available Explosion Limits: Upper: Not available Decomposition Temperature: Not available Solubility in water: 2.4 g/l water (20 C) Specific Gravity/Density: Molecular Formula: C9H16O4 Molecular Weight: 188.22 Chemical Stability: Conditions to Avoid: Incompatibilities with Other Materials Hazardous Decomposition Products Hazardous Polymerization RTECS#: Section 10 - Stability and Reactivity Stable under normal temperatures and pressures. Incompatible materials. Oxidizing agents, reducing agents, bases. Carbon monoxide, carbon dioxide. Will not occur. Section 11 - Toxicological Information CAS# 123-99-9: CM1980000 LD50/LC50: RTECS: CAS# 123-99-9: Draize test, rabbit, eye: 3 mg Mild; Draize test, rabbit, skin: 500 mg/24h Mild; Oral, rat: LD50 = >5 gm/kg;

. Carcinogenicity: Other: Not available Azelaic acid - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65. See actual entry in RTECS for complete information. The toxicological properties have not been fully investigated. Section 12 - Ecological Information Section 13 - Disposal Considerations Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - Transport Information IATA IMO RID/ADR Shipping Name: Not available Not available Not available Hazard Class: UN Number: Packing Group: European/International Regulations Section 15 - Regulatory Information European Labeling in Accordance with EC Directives Hazard Symbols:Not available Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) Canada CAS# 123-99-9: 1 CAS# 123-99-9 is listed on Canada's DSL List </ TD> US Federal TSCA CAS# 123-99-9 is listed on the TSCA Inventory. Section 16 - Other Information MSDS Creation Date: 7/16/1996 Revision #1 Date 5/03/2002 Revisions were made in Sections: General revision.

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantibility or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential, or exemplary damages howsoever arising, even if the company has been advised of the possibility of such damages. --------------------------------------------------------------------------------