Page 1 of 9 1 CHEMICAL PRODUCT AND COMPANY INFORMATION Product Description METHANOL-D (D, 99%) Cambridge Isotope Laboratories, Inc. 50 Frontage Rd ANDOVER, MA 01810 USA E-mail Web Site Phone Numbers Emergency Contact Emergency Phone Customer Service Phone Transportation cilsales@isotope.com www.isotope.com Chemtrec 1-800-424-9300 (24 hours) 1-800-322-1174 (8:30-5:30 EST) 1-202-483-7616 (24 hours) 2 HAZARDS IDENTIFICATION OSHA Hazards Flammable liquid, Target Organ Effect, Toxic by inhalation, Toxic by ingestion, Toxic by skin absorption, Irritant Target Organs Eyes, Kidney, Liver, Heart, Central nervous system GHS Classification Flammable liquids (Category 2) Acute toxicity, Oral (Category 3) Acute toxicity, Inhalation (Category 3) Acute toxicity, Dermal (Category 3) Skin irritation (Category 2) Eye irritation (Category 2) GHS Label Information Signal Word Danger Hazards Identification Flame
Page 2 of 9 Skull & crossbones Health hazard Hazard Statement(s) Highly flammable liquid and vapour. Toxic if swallowed or in contact with skin. Causes skin irritation. Causes serious eye irritation. Toxic if inhaled. Causes damage to organs. Precautionary Statement(s) Keep away from heat/sparks/open flames/hot surfaces- No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse with water for several minutes. Remove contact lenses. IF exposed: Call a POISON CENTER or doctor/physician. HMIS Ratings Chronic Health * Physical 0 Flammability 3 Health 2 NFPA Codes Fire 3 Health 2 Reactivity 0 Potential Health Effects Eyes Ingestion Inhalation Skin Causes eye irritation. Toxic if swallowed. May be harmful if inhaled. Causes respiratory tract irritation. Toxic if absorbed through skin. Causes skin irritation. 3 COMPOSITION / INFORMATION ON INGREDIENTS Composition / Information on Ingredients Synonyms Methyl alcohol Chemical Formula CH3OD Molecular Weight 33.05 CAS No. 1455-13-6 EC No. 200-659-6 Index No. 603-001-00-X
Page 3 of 9 4 FIRST AID MEASURES First Aid Measures Eyes Ingestion Inhalation Skin Additional Information Flush eye with water for 15 minutes. Get medical attention. Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get immediate medical attention. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. Move out of dangerous area. Consult a physician and show this safety data sheet. 5 FIRE FIGHTING MEASURE Fire Fighting Measures Extinguishing Media Fire Fighting Equipment Fire Fighting Procedures For small fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large fires, apply water from as far as possible. Use very large quantities (flooding) of water applied as a mist or spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Wear self contained breathing apparatus for fire fighting if necessary. Use water spray to cool unopened containers. 6 ACCIDENTAL RELEASE MEASURES Accidental Release Measures Personal Precautions Environmental Precautions Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Page 4 of 9 Methods and materials for containment and cleanup Contain spillage, then collect with non-combustible absorbent material. Disposal should be in accordance with applicable Federal, State and local regulations. 7 HANDLING AND STORAGE Precautions for Safe Handling Handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Use explosion-proof equipment. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electrostatic charge. Conditions for Safe Storage Storage Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. 8 EXPOSURE CONTROL / PERSONAL PROTECTION OSHA HAZARDOUS COMPONENTS (29 CFR 1910.1200) CHEMICAL NAME OSHA PEL ACGIH TLV METHANOL TWA 200 ppm 200 ppm STEL 250 ppm 250 ppm Personal Protecton Eyes - Face Skin Respiratory Protective Clothing Work Hygienic Practices Wear safety glasses with side shields (or goggles) and a face shield. Choose body protection according to the amount and concentration of the dangerous substance at the work place. When appropriate, use NIOSH/CEN approved respirator. Wear suitable protective clothing and gloves. Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. 9 PHYSICAL AND CHEMICAL PROPERTIES Physical and Chemical Properties (Unlabeled Compound) Form Liquid
Page 5 of 9 Color Odor Odor Threshold Colourless No data available No data available ph No data available Melting Point -98 C (-144 F) Boiling Point 64.7 C (148.5 F) Flashpoint 11.0 C (51.8 F) - closed cup Evaporation Rate No data available Lower Explosion 6% (V) Limit Upper Explosion 36% (V) Limit Vapor Pressure 546.6 hpa (410.0 mmhg) at 50.0 C (122.0 F) Vapor Density No data available Solubility in Water Completely miscible Partition Coefficient log Pow: -0.77 Auto Ignition 455 C (851 F) Temperature 10 STABILITY AND REACTIVITY Stability and Reactivity Chemical Stability Possibility of Hazardous Reactions Conditions to Avoid Hazardous decomposition products Materials to avoid Additional Information Stable if stored under recommended conditions. Vapors may form explosive mixture with air. Avoid Heat, Flames and Sparks. Hazardous decomposition products formed under fire conditions. - Carbon oxides Acid chlorides, Acid anhydrides, Oxidizing agents, Alkali metals Reducing agents, Acids 11 TOXICOLOGICAL INFORMATION Acute Toxicity
Page 6 of 9 LC50 Inhilation Rat LD50 Dermal Rabbit LD50 Oral Rat Serious Damage/Eye Irritation Skin Corrosion/Irritation Inhalation Respiratory or Skin Sensitization Germ Cell Mutagenicity IARC ACGIH NTP OSHA 4 h - 64000 ppm 15,800 mg/kg 5,628 mg/kg Eyes - rabbit - Eye irritation - 24 h Skin - rabbit - Skin irritation - 24 h No data available No component of this product present at levels greater than or equal to 0.1% is identifiable as probable, possible, or confirmed human carcinogen by IARC. No component of this product present at levels greater than or equal to 0.1% is identifiable as a carcinogen or potential carcinogen by ACGIH. No component of this product present at levels greater than or equal to 0.1% is identifiable as probable, possible, or confirmed human carcinogen by IARC. No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Specific Target Organ Toxicity Single Exposure Causes damage to organs Repeated Exposure No data available Other Information RTECS PC1400000 12 ECOLOGICAL INFORMATION Toxicity Toxicity to Fish LC50 Toxicity to Daphnia and Other Aquatic Invertebrates EC50 Persistance and Degradability Oncorhynchus mykiss (rainbow trout) - 19,000.00 mg/l - 96 h Daphnia magna (Water flea) - 24,500.00 mg/l - 48 h
Page 7 of 9 Bioaccumulative Potential Mobility in Soil PBT and vpvb Assessment Other Adverse Effects 13 DISPOSAL CONSIDERATIONS Disposal Considerations Product Disposal Waste materials should be disposed of under conditions which meet Federal, State, and Local environmental control regulations. 14 TRANSPORT INFORMATION Transportation Information-DOT/IATA/IMDG UN Number 1230 Prop. Ship. Name Methanol Hazard Class 3 Packing Group II Reportable Quantity 5000 lbs (RQ) DOT US Marine Pollutant No Poison Inhalation No Hazard 15 REGULATORY INFORMATION Regulatory Information Flammable liquid, Target Organ Effect, Toxic by inhalation, Toxic by ingestion, Toxic by skin absorption, Irritant SARA Sara 302 Component Sara 313 Component No chemicals in this material are subject to the reporting requirements. Yes
Page 8 of 9 SARA 311/312 Hazards Fire (Y/N) Acute (Y/N) Chronic (Y/N) Y Y Y STATE REGULATIONS Massachusetts Right to Know Pennsylvania Right to Know New Jersey Right to Know California Proposition 65 Yes Yes Yes WARNING! This product contains a chemical known by the state of California to cause birth defects or other reproductive harm. Canada DSL Status EU Hazard All components of this product are on the Canadian DSL list. Flammable. Toxic. Irritant. Safety Statements Keep away from sources of ignition - No smoking. Do not breathe dust. Do not breathe gas/fumes/vapour/spray. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). If swallowed, seek medical advice immediately and show this container or label. Risk Statements Highly flammable. Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes and skin. Danger of very serious irreversible effects. 16 OTHER INFORMATION Additional MSDS Information This product is not radioactive. The data given for this product are those of the corresponding unlabeled compound, unless specifically indicated otherwise. Health and safety data for labeled compounds are generally not available, but are assumed to be similar or identical to the corresponding unlabeled compound.
Page 9 of 9 Approved On 01/18/13 Version Number 4