Material Safety Data Sheet 1. CHEMICAL PRODUCT AND COMPANY INFORMATION Common Name: Vitamin B-12 Chemical Name: Methylcobalamin Synonyms: MeB12 Chemical Family: Vitamin Chemical Formula: C 63 H 91 CoN 13 O 14 P CAS Number: 13422-55-4 EINECS Number: 236-535-3 Supplier: Gurvey & Berry Co. Inc. 310 Judson Street, Unit #15 Toronto, ON, Canada, M8Z 5T6 Tel: (416) 259-5700 Fax: (416) 259-5417 E-mail: msds@gurveyberry.com Emergency Telephone: Canutec 613-996-6666 2. COMPOSITION AND INFORMATION ON INGREDIENTS Exposure Limits OSHA ACGIH Acute Toxicity LD 50 Ingredient CAS# % (pel) (tlv) (Oral, Dermal, I.V.) Methylcobalamin 13422-55-4 ca.100 Oral Rat >5000 mg/kg Other Information: 3. HAZARD IDENTIFICATION Environmental Hazards: Human Health Hazards Routes of Entry: Inhalation: yes Skin Contact: yes Ingestion: yes Signs and Symptoms of Exposure Ingestion: Inhalation: Skin Contact: Eye Contact: Medical Conditions Aggravated By Exposure: May be harmful if swallowed May be harmful if inhaled. May cause respiratory irritation. May cause skin irritation. May cause eye irritation Not known. 1
Toxicological Information Acute Toxicity LD 50 : Skin Corrosive Effect: Chemicals Listed as Carcinogenic or Potential Carcinogen: IARC Monograph: OSHA: NTP: Other: Mutagenic Effects Data: Reproductive Effects Data: Oral, rat: >5,000 mg/kg None known Questionable carcinogen with experimental neoplastigenic data. An experimental teratogen. Other experimental reproductive effects. 4. FIRST AID MEASURES General: Remove person from area of exposure. Thoroughly rinse mouth with water. Ingestion: If vomiting occurs, keep head lower than hips to avoid aspiration. Treat symptomatically and supportively, get medical attention immediately. Inhalation: Remove from exposure area to fresh air immediately. If breathing has stopped perform artificial respiration. Keep person warm and at rest. Get medical attention immediately. Skin Contact: Remove contaminated shoes and clothing immediately. Wash affected area with soap or mild detergent and large amounts of water until no evidence of the chemical remains. If irritation occurs seek medical attention. Eye Contact: Wash eyes immediately with large amounts of water or normal saline, occaisionally lifting the upper and lower lids until no evidence of the chemical remains. If irritation persists seek medical attention.. Protection of First Aiders: Refer to section 6. 5. FIRE FIGHTING MEASURES Suitable Extinguishing Media: Unsuitable Extinguishing Media: Hazardous Thermal Decomposition Products: Protection of Firefighters: Dry chemical, carbon dioxide, water spray or regular foam. For larger fires use water spray, fog, or regular foam. Thermal decomposition releases toxic oxides of phosphorous and nitrogen. Other toxic fumes. Avoid breathing vapours or dust, keep upwind. Use selfcontained breathing apparatus and full turn out gear. 6. EXPOSURE CONTROLS / PERSONAL PROTECTION 2
Engineering Measures: Hygienic Measures: Occupational Exposure Limits: ACGIH (tlv): OSHA (pel): Personal Protective Equipment Respiratory System: Skin and Body: Eyes: 7. HANDLING AND STORAGE Handling: Storage: Eyewash station and mechanical exhaust required. Follow good manufacturing practices. Any dust and mist respirator with a full face plate, any NIOSH-compliant air-purifying full facepiece respirator, standard N95 or better; any NIOSH-compliant selfcontained breathing apparatus with a full facepiece. Wear appropriate protective (impervious) clothing and equipment to prevent repeated or prolonged skin contact with this substance. Wear splash-proof or dust resistant safety goggles to prevent eye contact. No special handling procedures are recommended. Store in a well closed container, away from light. Store at temperatures below 0 C. 8. ACCIDENTAL RELEASE MEASURES Personal Precautions: As listed in section 6 Environmental Precautions: Methods for Cleaning Up: Sweep up, place in a suitable tightly closed container for disposal. Wash area with water after pick up is complete. 9. PHYSICAL AND CHEMICAL PROPERTIES Physical State: Will appear as crystals or as an amphorous or crystalline powder. Color: Red or dark red. Odor: Odorless. Odor Threshold: Molecular Weight: 1344.41 AMU Boiling Point: Melting Point: Specific Gravity (H 2 O=1): Decomposition Temperature: Bulk Density: Mean Particle Size: ph: Solubility in Water: Partially soluble Solubility in Other Agents: Insoluble In: Evaporation Rate (ethyl ether=1): Vapor Pressure (mmhg): 3
Vapor Density (air=1): Flash Point: Auto-ignition Temperature: Explosion Properties: Oxidation Properties: Other Properties: Negligible fire hazard when exposed to heat or flame. N/A 10. STABILITY AND REACTIVITY Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Humidity, heat, direct sunlight Materials to Avoid: Strong oxidizing agents Hazardous Decomposition Products: May release toxic oxides of phosphorous and nitrogen. Hazardous Polymerization: Has not been reported to occur under normal temperatures and pressures. 11. ECOLOGICAL INFORMATION N/A 12. DISPOSAL CONSIDERATIONS Wastes of Residues: Dispose of in accordance with all local, provincial, and federal regulations. Contaminated Packaging: Dispose of in accordance with all local, provincial, and federal regulations. 13. TRANSPORT INFORMATION Not regulated (DOT, TDG) 14. REGULATORY INFORMATION TSCA TSCA Inventory: Health and Safety Reporting List: Chemical Test Rules: Section 12b: Significant New Use Rule: SARA Section 302 (RQ): Section 302 (TPQ): SARA Codes: Section 313: Clean Air Act: Clean Water: OSHA: Subject to reporting European/International Regulations: 4
Hazard Symbols: Risk Phrases: Safety Phrases: CANADA DSL/NDSL: WHIMIS Classification: Ingredient Disclosure List: Not classified as hazardous according to CPR criteria. 15. OTHER INFORMATION This information is based upon knowledge currently available. More detailed information on the physical and chemical properties can be requested from the supplier. To the best of our knowledge, the information contained herein is accurate and complete. However, this should not be construed to imply any warranty or guarantee. Gurvey & Berry Co. Inc. shall not be held liable for any damage resulting from handling or from contact with the above chemical. Document Reference: 3647 Created On: March 5, 2010 Prepared By: Eugene M. Last Revised: Revised By:. Printed On: 21 February 2013 This document will only be updated as needed. 5