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SAFETY DATA SHEET Creation Date 24-v-2009 Revision Number 3 Product Name Cat. : Synonyms Recommended Use Uses advised against 1. Identification Salicylic Acid (USP) A275-500; A275-212; A275-12; A275-250LB 2-Hydroxybenzoic acid Laboratory chemicals. t for food, drug, pesticide or biocidal product use Details of the supplier of the safety data sheet Company Fisher Scientific One Reagent Lane Fair Lawn, NJ 07410 Tel: (201) 796-7100 Emergency Telephone Number CHEMTRECÒ, Inside the USA: 800-424-9300 CHEMTRECÒ, Outside the USA: 001-703-527-3887 2. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Acute oral toxicity Category 4 Serious Eye Damage/Eye Irritation Category 1 Combustible dust Yes Label Elements Signal Word Danger Hazard Statements May form combustible dust concentrations in air Harmful if swallowed Causes serious eye damage Precautionary Statements Prevention Page 1 / 7

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Wear protective gloves/protective clothing/eye protection/face protection Avoid breathing dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area Inhalation IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Call a POISON CENTER or doctor/physician if you feel unwell Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor/physician Ingestion IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell Rinse mouth Storage Store in a well-ventilated place. Keep container tightly closed Store locked up Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC) ne identified 3. Composition / information on ingredients Component CAS- Weight % Salicylic acid 69-72-7 >95 4. First-aid measures Eye Contact Skin Contact Inhalation Ingestion Most important symptoms/effects tes to Physician Suitable Extinguishing Media Unsuitable Extinguishing Media Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention if symptoms occur. Move to fresh air. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Get medical attention if symptoms occur. If not breathing, give artificial respiration. Do not induce vomiting. Call a physician or Poison Control Center immediately. Causes eye burns. Causes severe eye damage. Treat symptomatically 5. Fire-fighting measures Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Flash Point 157 C / 314.6 F Method - Autoignition Temperature 535 C / 995 F Explosion Limits Page 2 / 7

Upper data available Lower 1.1% @ 200 C Sensitivity to Mechanical Impact Sensitivity to Static Discharge Specific Hazards Arising from the Chemical Dust can form an explosive mixture in air. Fine dust dispersed in air may ignite. Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and sources of ignition. Hazardous Combustion Products Carbon monoxide (CO) Carbon dioxide (CO2) Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. NFPA Health 2 Flammability 1 Instability 0 Physical hazards N/A Personal Precautions Environmental Precautions 6. Accidental release measures Use personal protective equipment. Ensure adequate ventilation. Avoid dust formation. Avoid contact with skin, eyes and clothing. Avoid release to the environment. See Section 12 for additional ecological information. Methods for Containment and Clean Sweep up or vacuum up spillage and collect in suitable container for disposal. Avoid dust Up formation. Handling Storage Exposure Guidelines 7. Handling and storage Wear personal protective equipment. Ensure adequate ventilation. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Avoid dust formation. Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from direct sunlight. 8. Exposure controls / personal protection This product does not contain any hazardous materials with occupational exposure limitsestablished by the region specific regulatory bodies. Engineering Measures Ensure that eyewash stations and safety showers are close to the workstation location. Ensure adequate ventilation, especially in confined areas. Personal Protective Equipment Eye/face Protection Skin and body protection Respiratory Protection Hygiene Measures Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Wear appropriate protective gloves and clothing to prevent skin exposure. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Handle in accordance with good industrial hygiene and safety practice. Page 3 / 7

9. Physical and chemical properties Physical State Solid Appearance Off-white Odor Slight Odor Threshold ph 3.6 sat. solution Melting Point/Range 158-161 C / 316.4-321.8 F Boiling Point/Range 211 C / 411.8 F @ 20 mmhg Flash Point 157 C / 314.6 F Evaporation Rate Flammability (solid,gas) Flammability or explosive limits Upper data available Lower 1.1% @ 200 C Vapor Pressure 0.3 mbar @ 95 C Vapor Density Specific Gravity Solubility Soluble in water Partition coefficient; n-octanol/water data available Autoignition Temperature 535 C / 995 F Decomposition Temperature Viscosity Molecular Formula C7 H6 O3 Molecular Weight 138.12 10. Stability and reactivity Reactive Hazard Stability Conditions to Avoid Incompatible Materials ne known, based on information available Stable under normal conditions. Light sensitive. Moisture sensitive. Avoid dust formation. Incompatible products. Excess heat. Exposure to moisture. Exposure to light. Strong oxidizing agents Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2) Hazardous Polymerization Hazardous Reactions Acute Toxicity Hazardous polymerization does not occur. ne under normal processing. 11. Toxicological information Product Information Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation Salicylic acid LD50 = 891 mg/kg ( Rat ) LD50 > 2 g/kg ( Rat ) >0.9 mg/l ( Rat ) 1 h Toxicologically Synergistic Products Delayed and immediate effects as well as chronic effects from short and long-term exposure Irritation Sensitization Carcinogenicity Severe eye irritant The table below indicates whether each agency has listed any ingredient as a carcinogen. Page 4 / 7

Component CAS- IARC NTP ACGIH OSHA Mexico Salicylic acid 69-72-7 t listed t listed t listed t listed t listed Mutagenic Effects Reproductive Effects Developmental Effects Teratogenicity STOT - single exposure STOT - repeated exposure Aspiration hazard Symptoms / effects,both acute and delayed Endocrine Disruptor Information Other Adverse Effects Ecotoxicity.... ne known ne known The toxicological properties have not been fully investigated. 12. Ecological information Component Freshwater Algae Freshwater Fish Microtox Water Flea Salicylic acid t listed LC50: = 90 mg/l, 48h static (Leuciscus idus) EC50 = 138 mg/l 1 h EC50 = 214 mg/l 5 min EC50 = 552 mg/l 1 h EC50 = 78 mg/l 210 min EC50: 105 mg/l/24h Persistence and Degradability Soluble in water Persistence is unlikely based on information available. Bioaccumulation/ Accumulation Mobility.. Will likely be mobile in the environment due to its water solubility. Component log Pow Salicylic acid 2.26 Waste Disposal Methods DOT TDG IATA IMDG/IMO 13. Disposal considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. 14. Transport information t regulated t regulated t regulated t regulated 15. Regulatory information All of the components in the product are on the following Inventory lists: X = listed International Inventories Component TSCA DSL NDSL EINECS ELINCS NLP PICCS ENCS AICS IECSC KECL Page 5 / 7

Salicylic acid X X - 200-712-3 - X X X X X Legend: X - Listed E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA. F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA. N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used. P - Indicates a commenced PMN substance R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA. S - Indicates a substance that is identified in a proposed or final Significant New Use Rule T - Indicates a substance that is the subject of a Section 4 test rule under TSCA. XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base Production and Site Reports (40 CFR 710(B). Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater. Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants that comprises one of the eligibility criteria for the exemption rule. U.S. Federal Regulations TSCA 12(b) SARA 313 SARA 311/312 Hazard Categories Acute Health Hazard Chronic Health Hazard Fire Hazard Sudden Release of Pressure Hazard Reactive Hazard Yes CWA (Clean Water Act) Clean Air Act OSHA Occupational Safety and Health Administration CERCLA California Proposition 65 U.S. State Right-to-Know Regulations This product does not contain any Proposition 65 chemicals U.S. Department of Transportation Reportable Quantity (RQ): DOT Marine Pollutant DOT Severe Marine Pollutant N N N U.S. Department of Homeland Security This product does not contain any DHS chemicals. Other International Regulations Mexico - Grade Slight risk, Grade 1 Prepared By 16. Other information Regulatory Affairs Thermo Fisher Scientific Email: EMSDS.RA@thermofisher.com Page 6 / 7

Creation Date Revision Date Print Date Revision Summary 24-v-2009 24-May-2017 24-May-2017 This document has been updated to comply with the US OSHA HazCom 2012 Standard replacing the current legislation under 29 CFR 1910.1200 to align with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text End of SDS Page 7 / 7