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GCE Biology Advanced GCE A2 H421 Advanced Subsidiary GCE AS H021 Mark Scheme for the Units January 2010 HX21/MS/R/10J Oxford Cambridge and RSA Examinations

F211 Cells, Exchange and Transport 1 (a) 1500 ; ACCEPT 1400 and 300,000 for 1 max only 500 000 ; 2 1 (b) ability to see (two) objects (that are close together) as separate objects / AW ; see detail ; 2 ACCEPT ability to distinguish two objects IGNORE clarity / clear 1 (c) (i) transports water (up plant) ; ACCEPT alternative wording for transport e.g. movement DO NOT ACCEPT up and down DO NOT ACCEPT water and sugars transports, minerals / ions, (up plant) ; ACCEPT alternative wording for transport IGNORE ref nutrients / solutes DO NOT ACCEPT sugars support (plant / stem / shoot) ; 1 max ACCEPT keeps plant upright 1

1 (c) (ii) Functions: F1 (lignin), strengthens / thickens, the (xylem) wall ; F2 waterproofing (wall) / AW ; ACCEPT support only if in specific context of supporting the xylem wall ACCEPT waterproofs cell F3 (improving) adhesion of water (molecules) ; F4 (spiral) pattern allows flexibility / stretching / movement; 2 max Explanation: E1 prevents collapse of xylem ; E2 (water) under tension / at low pressure / negative pressure; E3 reduces (lateral) loss of water, through wall ; E4 increases capillarity / AW ; E5 prevents stem breaking / AW ; 2 max 3 max DO NOT ACCEPT adhesion and cohesion when used together Flexibility / stretching must ref, pattern of lignin laid down i.e. spirals Award mark(s) for function and explanation independently DO NOT CREDIT loss of water unqualified 2

1 (c) (iii) (pits) allow water to move, in / out / between, vessel(s) ; to bypass blockage ; supply water to other, tissues / (other types) cells / parts of plant ; 2 max ACCEPT lateral movement for out ACCEPT bypass air lock ACCEPT any named, tissue / cells e.g. to allow water to other tissues 1 mark to allow water out to other tissues 1 mark to allow water out of vessel to other tissues 2 marks Total 10 3

2 (a) (i) collection / group, of cells (of one or more types) ; IGNORE ref similar cells (cells), working together OR with, common / same, function ; ACCEPT a group of cells with a function = 2 marks specialised (cells) ; 2 max DO NOT CREDIT differentiated 2 (a) (ii) squamous / ciliated ; 1 ACCEPT endothelium / columnar DO NOT ACCEPT cilia, goblet cell, ciliated cells 2 (b) (organ is) a collection of tissues / named tissues ; Look for idea of more than one tissue ACCEPT two or more correctly named tissues from: epithelium, elastic, glandular, smooth muscle, blood, nervous, cartilage, connective (working together) to enable gas exchange / AW ; 2 DO NOT ACCEPT perform a function unqualified we want to know what function (can be named or described) DO NOT ACCEPT respiration IGNORE breathing 4

2 (c) (i) (release of energy) mitochondria ; 1 (ii) (movement of cilia) cytoskeleton ; 1 ACCEPT mitochondria if not used in (i) (iii) (secretion of mucus) Golgi (vesicle) ; 1 Total 8 ACCEPT cytoskeleton if not used in (ii) ACCEPT Golgi body / apparatus DO NOT ACCEPT Golgi vessel 5

DO NOT ACCEPT semi 3 (a) partially / selectively ; ACCEPT differentially (facilitated) diffusion OR osmosis ; plasma ; phospholipids ; cholesterol ; 5 ACCEPT plasma cell 6

3 (b) 1 (acting as) antigens ; 2 identification / recognition, (of cells) as, self / non-self / AW ; 3 cell signalling / described ; 4 receptor / binding site, for, hormone / (chemical) signal / (medicinal / named) drugs ; 5 ref. to receptor / binding site / trigger, on transport proteins / AW ; 6 cell adhesion / to hold cells together (in a tissue) ; 7 attach to water molecules (to stabilise membrane / cell) ; 4 max for description Look for description not list of functions Do not credit repetition of same point ACCEPT foreign for non-self ACCEPT description e.g. communication between cells / cell responds to, chemical / signal, from another cell ACCEPT description of attachment process for receptor / binding site DO NOT ACCEPT molecule unqualified ACCEPT binding site for foreign antigen ACCEPT ref to receptors on ion channels ACCEPT bind to other cells for cell adhesion QWC: three technical terms used and spelt correctly ; 5 max Total 10 Any three from: receptor, antigen, hormone, cell signal(ling), adhesion, recognition, facilitated diffusion, active transport 7

Question Expected Answers Mark Additional Guidance 4 (a) timer OR scale / ruler ; 1 4 (b) Mark the first three suggestions irrespective of numbered points IGNORE reasons just mark steps in the process shoot is healthy ; ACCEPT shoot not wilted assemble apparatus / cut shoot, under water ; cut last 2-3 cm off cut end / cut at an angle ; check there are no air bubbles in apparatus ; apparatus, water tight / air tight / has no leaks ; ACCEPT cut end off shoot ACCEPT make sure cut end of shoot is in contact with water once apparatus assembled ACCEPT screw clip tight DO NOT ACCEPT use Vaseline unqualified leaves dry ; 3 max DO NOT CREDIT allow time for acclimatisation, equilibration 8

Question Expected Answers Mark Additional Guidance 4 (c) (i) 25.3 ; 1 IGNORE any units 4 (c) (ii) to make results (more) reliable ; DO NOT ACCEPT accurate and reliable (use of both terms) anywhere in the answer 4 (c) (iii) to help identify anomalies ; in afternoon: plant dying / less healthy / wilting ; ref to stomatal closure ; more humid / higher water (vapour) potential in air ; less air movement / wind / draughts ; 2 2 max Look for idea of spotting the anomaly e.g. spot, notice, recognise, show, detect. DO NOT CREDIT prevents / take out / remove / accounts for, anomalies DO NOT CREDIT ensure there is no anomaly unless qualified ACCEPT outliers for anomalies ACCEPT to identify other factors / (uncontrolled) variables that may be having an effect Mark first response in each numbered section (1-2). If not all sections are used, return to the first section and mark further suggestions Assume answer is for different conditions in the afternoon ACCEPT ORA if stated in morning... IGNORE ref to light / dark Look for comparative statements higher, greater etc DO NOT CREDIT more moisture in air 9

Question Expected Answers Mark Additional Guidance 4 (c) (iv) (potometer) measures (water) uptake ; not all water (taken up) is lost ; ACCEPT ref to figs e.g. 99% water taken up is lost ACCEPT the assumption that water loss is equal to water uptake is incorrect some water used (in photosynthesis / making cells turgid) ; 2 max Total 11 10

5 (a) (i) vein with thinner wall than artery ; CREDIT: Correct position of endothelium as indicated by circle or label line Must be clearly thinner than shown on artery DO NOT CREDIT: 1 11

Question Expected Answers Mark Additional Guidance 5 (a) (ii) Arteries have: no valves ; endothelium / tunica intima, folded / AW ; more / thicker, muscle / elastic tissue / tunica media ; more / thicker, collagen / tunica externa ; 2 max Assume answer refers to wall of artery. IGNORE any ref to artery wall being thicker, unqualified, as this has already been stated in the question IGNORE reasons for differences ACCEPT ORA if stated - vein is... Look for comparative statements ACCEPT tunica adventitia for tunica externa 5 (b) (i) contraction of ventricle, wall / muscle ; 1 ACCEPT ventricular systole DO NOT CREDIT heart muscle unqualified DO NOT CREDIT contraction of atria and ventricles DO NOT CREDIT pump / squeeze / push / beat without ref to contraction 12

Marks Expected Answers Mark Additional Guidance 5 (b) (ii) more, (smaller) vessels / named vessels ; (vessels) have larger, total lumen / cross sectional area ; ACCEPT divides into smaller vessels (implies more of them) ACCEPT larger total surface area reduced resistance to blood flow ; DO NOT CREDIT further from the heart arteries, stretch / expand ; 5 (b) (iii) loss of, fluid / plasma, from capillaries ; 2 max DO NOT CREDIT loss of, blood / water DO NOT CREDIT loss of fluid / plasma, unqualified or from other vessels Assume it refers to plasma: plasma / fluid, moves out of, capillary / blood ; enters / forms, tissue fluid ; DO NOT CREDIT water / diffuses out ACCEPT filters out (plasma) proteins, remain in capillary / too large to pass through capillary wall / AW ; (fluid moves) down pressure gradient ; hydrostatic pressure greater than, water potential / Ψ; 3 max DO NOT CREDIT ref to osmosis 13

Marks Expected Answers Marks Additional Guidance 5 (c) X = carbonic anhydrase ; ACCEPT correct phonetic spelling DO NOT ACCEPT anahydrase Y = carbonic acid / H 2 CO 3 ; If formula only given, it must be correct. Incorrect formula can be ignored if correct name given. Z = hydrogen (ion) / H + ; 3 DO NOT CREDIT H alone Total 12 14

6 (a) (i) First two points are marked independently diaphragm / intercostal muscles, contract : DO NOT CREDIT internal intercostal muscles contract diaphragm moves down / ribs move upwards and outwards ; volume of thorax increased ; pressure inside thorax falls ; to below atmospheric pressure (so air enters lungs) ; 2 max for mechanism DO NOT CREDIT diaphragm flattens alone ACCEPT movement of diaphragm pushes digestive organs down DO NOT ACCEPT expands (for increased volume) DO NOT ACCEPT size for volume ACCEPT capacity for volume ACCEPT lungs / chest (cavity), for thorax DO NOT CREDIT pressure gradient alone - direction of gradient must be specified QWC: accept three technical terms used and spelt correctly ; 3 max accept any three from: diaphragm, intercostal, volume, pressure, thorax, thoracic cavity 15

6 (a) (ii) it falls / goes down / AW ; 1 ACCEPT decreases in volume / volume gets smaller DO NOT CREDIT empties, closes, flattens, deflates, becomes smaller DO NOT ACCEPT amount for volume 6 (iii) soda lime / sodium hydroxide / potassium hydroxide / calcium hydroxide ; 1 ACCEPT correct formulae NaOH / KOH / Ca(OH) 2 DO NOT ACCEPT calcium oxide ACCEPT limewater, lime soda 6 (b) to ensure all air breathed comes from chamber OR to prevent, escape of air / entry of air, through nose ; make results invalid ; 2 max ACCEPT air may be breathed in or out through nose ACCEPT ensures breathes through mouth DO NOT ACCEPT ref accuracy, reliability, false results DO NOT ACCEPT invalid and accuracy / reliability (use of both terms) anywhere in the answer 16

Marks Expected Answers Marks Additional Guidance 6 (c) use (medical grade) oxygen / fresh air ; disinfect mouthpiece ; ref. to health of subject ; Note question relates to measuring vital capacity ACCEPT ensure there is enough oxygen / air ACCEPT change / wash mouthpiece e.g. asthmatics ref to correct functioning of equipment ; 2 max Total 9 e.g. maintain constant temperature (so that volume of gases is not affected) ensure, valve / hinge, is working level of water correct no leaks / airtight / lips sealed around mouthpiece 17

Grade Thresholds Advanced GCE (Biology) (H021 H421) January 2010 Examination Series Unit Threshold Marks F211 F212 F214 Unit Maximum A B C D E U Mark Raw 60 40 35 31 27 23 0 UMS 90 72 63 54 45 36 0 Raw 100 69 62 56 50 44 0 UMS 150 120 105 90 75 60 0 Raw 60 40 36 32 28 25 0 UMS 90 72 63 54 45 36 0 Specification Aggregation Results Overall threshold marks in UMS (ie after conversion of raw marks to uniform marks) Maximum A B C D E U Mark H021 300 240 210 180 150 120 0 The cumulative percentage of candidates awarded each grade was as follows: A B C D E U Total Number of Candidates H021 8.8 28.6 54.1 78.4 95.1 100.0 1505 1505 candidates aggregated this series For a description of how UMS marks are calculated see: http://www.ocr.org.uk/learners/ums/index.html Statistics are correct at the time of publication. 54