Safety Data Sheet. Emergency Phone Number: U.S. and Canada: (800) International: (352) (INFOTRAC)

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SDS Safety Data Sheet 1. IDENTIFICATION Product Identifier: Product Code(s): Synonyms: Recommended Use: Uses Advised Against: Supplier: New Methylene Blue Stain J0324, J0324A Mixture. For invitro veterinary use only. t for use on humans. Jorgensen Laboratories 1450 Van Buren Avenue, Loveland, CO 80538 Phone: (970) 669-2500 or (800) 525-5614 Fax: (970) 663-5042 Emergency Phone Number: U.S. and Canada: (800) 535-5053 International: (352) 323-3500 (INFOTRAC) 2. HAZARDS IDENTIFICATION Hazard Classifications: Signal Word: Hazard Statements: Pictograms: This product is classified as nonhazardous under OSHA's Hazard Communication Standard, 29 CFR 1910.1200 (HCS) and the United Nations Globally Harmonized System of Classification and Labeling of Chemicals (GHS). However, all chemicals handled and used in the workplace should be treated with caution. Precautionary Statements: Prevention: Response: Storage: Disposal: Hazards t Otherwise Classified: Toxicity Statement: This product contains >1% ingredients whose acute toxicity is unknown. Revision Date: 10/10/2016 1/7

3. COMPOSITION AND INFORMATION ON INGREDIENTS Component Common Name / Synonyms CAS# Chemical Formula % by Weight Water Water 7732-18-5 H2O >97 nhazardous ingredients N/A N/A N/A <3 Trade Secret Statement: The identifiers and concentrations of the nonhazardous ingredients have been withheld under a trade secret. These components are either nonhazardous or are present at sufficiently low concentrations such that they do not affect the hazard classification of this product. 4. FIRST AID MEASURES First Aid Procedures: Inhalation: Ingestion: Move to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. If symptoms occur, call a poison center or doctor immediately. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, keep head low so that vomit does not enter lungs. Never give anything by mouth to an unconscious person. If symptoms occur, call a poison center or doctor immediately. Skin Contact: Remove contaminated clothing and shoes. Wash skin with plenty of water for at least 15 minutes. Wash clothing before reuse. If symptoms occur, call a poison center or doctor immediately. Eye Contact: General Advice: Symptoms and Effects: Immediate Medical Care/ Special Treatment: Check for and remove contact lenses if present and easy to do. Immediately flush eyes with gentle but large stream of water for at least 15 minutes, lifting lower and upper eyelids occasionally. If symptoms occur, call a poison center or doctor immediately. Ensure that medical personnel and those providing first aid are aware of the material(s) involved and take precautions to protect themselves. Irritation, nausea, vomiting, diarrhea, abdominal pain. May be harmful if swallowed. May cause irritation to the eyes, skin, respiratory tract, and gastrointestinal tract. If you feel unwell or are concerned, call a physician or poison control center immediately. Treat symptomatically. 5. FIREFIGHTING MEASURES Suitable Extinguishing Media: Water spray, dry powder, alcohol resistant foam, carbon dioxide. Unsuitable Extinguishing Media: Do not use a solid (straight) water stream, as it may scatter and spread fire. Hazardous Combustion Products: Specific Hazards: Special Protective Equipment/ Precautions for Firefighters: Toxic fumes. Excessive thermal conditions may cause decomposition and yield hazardous decomposition products listed above. As in any fire, wear MSHA/NIOSH-approved (or equivalent), self-contained, positivepressure or pressure-demand breathing apparatus and full protective gear. In the event of fire and/or explosion, do not breathe fumes. Revision Date: 10/10/2016 2/7

6. ACCIDENTAL RELEASE MEASURES Personal Precautions and Protective Equipment: Emergency Procedures: Methods for Containment: Methods for Cleanup: Isolate hazard area and keep unnecessary and unprotected personnel away from the area of the leak or spill. Wear appropriate personal protective equipment (see Section 8). Avoid contact with eyes, skin, and clothing. In case of chemical emergency, or if unsure how to address an accidental release, consult a professional (see Section 1). Stop the flow of material, if this is without risk. Prevent entry into waterways, sewer, basements, or confined areas. Dike the spilled material, where this is possible. Product should not be released to the environment. Contain and recover liquid when possible. Absorb spill with an inert material (e.g. vermiculite, dry sand, earth, cloth, or fleece) and place in a noncombustible container for reclamation or disposal. Do not flush to sewer. Clean contaminated surface thoroughly. Spills can be dissolved with alcohol or acetone solution. Never return spills in original containers for reuse. Clean up in accordance with all applicable regulations. 7. HANDLING AND STORAGE Handling: Storage: Avoid contact with skin, eyes, and clothing. Do not breathe vapors or spray mist. Do not ingest. When using, do not eat, drink, or smoke. Keep away from incompatible materials (see Section 10). Handle in accordance with good industrial hygiene and safety practice. Wash thoroughly after handling. Containers of this material may be hazardous when empty, as they retain product residues. Observe all warnings and precautions listed for this product. Store in a cool, dry, ventilated area. Store away from incompatible materials (see Section 10). Store in original container. Keep containers tightly closed and upright. Keep away from food, drink, and animal foodstuffs. Keep out of the reach of children. Comply with all national, state, and local codes pertaining to the storage, handling, dispensing, and disposal of this product. 8. EXPOSURE CONTROLS AND PERSONAL PROTECTION Exposure Limits: Water: nhazardous ingredients: Engineering Controls: Ensure adequate ventilation. Ventilation rates should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits. If exposure limits have not been established, maintain airborne levels to an acceptable level. Personal Protective Measures: Eye/Face Protection: Skin Protection: Wear safety glasses with side shields or safety goggles. Maintain approved eye wash station and accessible rinse facilities in work area. Wear appropriate chemical resistant clothing (with long sleeves) and appropriate chemical resistant gloves. Respiratory Protection: An air-purifying, NIOSH-approved respirator with appropriate cartridge or canister may be permissible under certain circumstances where airborne concentrations are expected to exceed exposure limits. Use a positive-pressure, air-supplied respirator if there is any Revision Date: 10/10/2016 3/7

potential for an uncontrolled release, if exposure levels are unknown, or if any other circumstances exist where air-purifying respirators may not provide adequate protection. Specific Requirements for Personal Protective Equipment: Ensure that glove material is compatible with this product. This information is available from glove manufacturers. 9. PHYSICAL AND CHEMICAL PROPERTIES Unless otherwise indicated, all properties are given at 25 C and standard pressure. Appearance: Odor: Odor Threshold: Formula Weight: ph: Blue, opaque liquid. Slight, mild. Mixture. Melting/Freezing Point: 0 C Boiling Point/Range: 100 C Decomposition Temperature: Flash Point: Auto-ignition Temperature: Flammability: Flammability/Explosive Limits: Solubility: Vapor Pressure: Vapor Density: t flammable or explosive. Miscible with water. Specific Gravity: 1.005 (Water = 1) Evaporation Rate: Viscosity: Partition Coefficient (n-octanol/water): 10. STABILITY AND REACTIVITY Reactivity Data: Chemical Stability: Conditions to Avoid: Incompatible Materials: Hazardous Decomposition Products: Possibility of Hazardous Reactions: Stable under normal conditions. Heat, incompatible materials. Oxidizing agents, strong bases. Toxic fumes. May react vigorously or violently if exposed to extreme thermal conditions or if contacted with the incompatible materials listed above. Revision Date: 10/10/2016 4/7

Hazardous Polymerization: Will not occur. 11. TOXICOLOGICAL INFORMATION Routes of Exposure: Acute Effects: Chronic Effects: Inhalation, ingestion, skin contact, eye contact. May be harmful if swallowed. May cause irritation to the eyes, skin, respiratory tract, and gastrointestinal tract. Toxicological Data: Water: nhazardous ingredients: Symptoms of Exposure: Carcinogenic Effects: Irritation, nausea, vomiting, diarrhea, abdominal pain. component of this product is considered to be a carcinogen by IARC, ACGIH, NTP, or OSHA. 12. ECOLOGICAL INFORMATION Ecotoxicological Data: Water: nhazardous ingredients: Persistence and Degradability: Environmental Effects: May not be readily biodegradable. t expected to be hazardous to the environment. However, the possibility of an environmental hazard cannot be excluded in the event of unprofessional handling or disposal. 13. DISPOSAL INFORMATION Disposal Instructions: Contaminated Packaging: Waste Codes: All wastes must be handled in accordance with local, state, and federal regulations. Minimize exposure to product waste (see Section 8). Because emptied containers retain product residue, follow label warnings even after container is emptied. Offer rinsed packaging material to local recycling facilities. 14. TRANSPORT INFORMATION DOT: Environmental Hazard Regulations: Other Transport Precautions: t regulated. Revision Date: 10/10/2016 5/7

15. REGULATORY INFORMATION U.S. Federal Regulations: OSHA: This product is not considered a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200. TSCA Inventory: All components of this product are on the U.S. TSCA Inventory. U.S. EPCRA (SARA Title III): Section 302: Sections 311/312: Hazard Category Section 311 Hazardous Chemical Immediate Hazard Delayed Hazard Fire Hazard Pressure Hazard Reactivity Hazard List (Yes/) Section 313: CERCLA Reportable Quantities: Canada WHMIS: This SDS is prepared in compliance with the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). Therefore, it complies with the 2015 Workplace Hazardous Materials Information System (WHMIS) as well. International Inventories: Country or Region Inventory Name On Inventory (Yes/)* Australia Australian Inventory of Chemical Substances (AICS) Yes Canada Domestic Substances List (DSL) Yes Canada n-domestic Substances List (NDSL) China Inventory of Existing Chemical Substances in China (IECSC) Yes Europe European Inventory of Existing Commercial Chemical Substances Yes (EINECS) Europe European List of tified Chemical Substances (ELINCS) Japan Inventory of Existing and New Chemical Substances (ENCS) Yes Korea Existing Chemicals List (ECL) Yes Philippines Philippine Inventory of Chemicals and Chemical Substances (PICCS) Yes *A "Yes" indicates that the listed components of this product comply with the inventory requirements administered by the governing country or region. Revision Date: 10/10/2016 6/7

16. OTHER INFORMATION Disclaimer: Jorgensen Laboratories provides the information in this Safety Data Sheet in the belief that it is reliable but assumes no responsibility for its completeness or accuracy. The physical properties reported in this SDS are obtained from literature and do not constitute product specifications. Jorgensen Laboratories makes and gives no representations or warranties with respect to the information contained herein or the product to which it refers, whether express, implied, or statutory, including without limitation, warranties of accuracy, completeness, merchantability, non-infringement, performance, safety, suitability, stability, and fitness for a particular purpose. warranty against infringement of any patent, copyright or trademark is made or implied. This SDS is intended only as a guide to the appropriate handling of the material by a properly trained person. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. Accordingly, Jorgensen Laboratories assumes no liability whatsoever for the use of or reliance upon this information including results obtained, incidental or consequential damages, or lost profits. Issue Date: October 10, 2016 Reason for Revision: Update of Sections 8, 9, 11, 12, and 15 over 02/23/2015 version. Revision Date: 10/10/2016 7/7