Ventilators. Dr Simon Walton Consultant Anaesthetist Eastbourne DGH KSS Basic Science Course

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Ventilators Dr Simon Walton Consultant Anaesthetist Eastbourne DGH KSS Basic Science Course

Objectives Discuss Classification/ terminology Look at Modes of ventilation How some specific ventilators work Questions

What is a mechanical ventilator? A machine that generates a controlled flow of gas into a patient s airways Most commonly gas flows along a pressure gradient between the upper airway and the alveoli. (Positive Pressure Ventilation) The magnitude, rate and duration of flow are determined by the operator.

How are mechanical ventilators classified? Lots of different classifications Many historical Depends which textbook Can be confusing Often same words used for different meanings

Negative v Positive Negative-pressure ventilators ( iron lungs ) Used extensively during polio outbreaks in 1940s 1950s Positive-pressure ventilators Now the modern standard of mechanical ventilation Uses pressures above atmospheric pressure to push air into lungs Requires use of artificial airway

Classification continued Mechanism of Action (historical) Mechanical thumbs, Minute volume dividers, Bag squeezers, Intermittent blowers Mapleson Constant Flow generators: High pressure/ constant flow Constant Pressure generators: Low pressure/ variable flow Cycling (from I to E) Pressure, Volume, Time or Flow

Volume v Pressure Flow can be either volume targeted or pressure targeted Volume: Most widely used system Terminates inspiration at preset volume Delivers volume at whatever pressure is required up to specified peak pressure May produce dangerously high intrathoracic pressures

Volume v Pressure Flow can be either volume targeted or pressure targeted Pressure: Terminates inspiration at preset pressure Avoid barotrauma Ventilation volume can vary with changes in airway resistance, pulmonary compliance

Terminology Control Cycling Triggering Mode

Terminology Control Two meanings How the ventilator knows how much flow to deliver Volume - flow generated according to preset volume Volume Controlled Ventilation Pressure - flow generated according to preset pressure Pressure Controlled Ventilation Pt receives a set number of breaths and cannot breathe between ventilator breaths As in Control Mode/ Controlled Mandatory Ventilation

Terminology Cycling How the ventilator switches from inspiration to expiration. Pressure Cycled - older simpler ventilators - Manley Volume Cycled Time Cycled Flow cycled - commonest system - when setting inspiratory pauses etc - used in Pressure Support

Terminology Triggering How the ventilator cycles from expiration to inspiration. Time triggered the ventilator cycles at a set frequency as determined by the controlled rate. Typical theatre ventilator doing CMV Pressure triggered the ventilator senses the patient's inspiratory effort by way of a decrease in the baseline pressure PS mode Flow triggered the ventilator senses the patient's inspiratory effort by change in flow Less effort, constant flow generated, modern ITU ventilators PS mode

Terminology Mode Describes the pattern of breaths delivered CMV, Assist Control, (S)IMV, PS, PCV CMV - Controlled Mandatory Ventilation No allowances for spontaneous breathing. Many anaesthesia ventilators operate in this way. AC - Assist Control Pt triggers breaths assisted breaths are facsimiles of controlled breaths. Old mode

Terminology - Mode IMV IMV and SIMV Developed to facilitate liberation from mechanical ventilation Demand valve placed in the breathing system Gas for spont breath diverted to avoid usual ventilator circuit (high resistance) Gas derived from reservoir bag Mandatory breaths reduced until pt breathing on CPAP only

Problems with IMV Stacking - spont breath and machine breath occur together. Work - spont breaths not supported

Terminology - Mode SIMV Similar to IMV Microprocesor technology Mandatory breaths synchronised to avoid stacking by: Machine breaths initiated by patient breath (Flow/ pressure triggered) Machine breaths timed to delay ventilations until end of spontaneous patient breaths Spontaneous breaths above mandatory rate supported by Pressure Support. - less work

Terminology - Mode Pressure Support Used as a partial or full support mode Patient triggers the ventilator (pressure/ flow triggered) The ventilator delivers a flow up to a preset pressure limit Patient controls duration of breath Flow cycled Flow cycles off when flow declines to a certain percentage of peak inspiratory flow (5-25% depending on type of ventilator)

Pressure Controlled Ventilation (PCV) Flow generated according to preset pressure Peak Pressure Many different modes can be pressure controlled eg CMV, SIMV or AC Flow waveform is always decelerating Flow slows as it reaches the pressure limit. Improve the distribution of ventilation in a lung with heterogeneous mechanical properties (as in acute lung injury) Gas distribution in pressure control is like dropping a glass of water on the floor: the water trickles into every nook and cranny Burke et al. Comparison of mathematical and mechanical models of pressure-controlled ventilation. J Appl Physiol 1993; 74(2):922-933.

Terminology - Mode Pressure Control Ventilation Advanced Modes Developed for treatment of ARDS Frequently ARDS pt require inverse ratio ventilation. With traditional pressure control CMV or SIMV uncomfortable for pt Often require heavy sedation/ paralysis Leads to resp muscle and diaphragmatic weakness.

Terminology - Mode APRV (Airway Pressure Release Ventilation) Advanced Pressure Control Mode Ventilator cycles between two different levels of CPAP Base line pressure is phigh Cycles to plow to facilitate CO2 removal phigh time > plow time (inverse ratio) Pt can breath spontaneously on top of this more comfortably

Terminology - Mode BIPAP or DUOPAP Advanced Pressure Control Mode Bi-level CPAP correct term BIPAP correct term used for mode of Noninvasive ventilation Advance on APRV allows easier breathing on top of two levels of CPAP Allows Pressure Support of spont breaths Advantage better tolerated and less sedation other modes of pressure control.

What is the Plateau Pressure? VCV only (PCV: phigh/ limit = plateau pressure) True reflection of alveolar pressure

What is the difference between PEEP and CPAP? Used interchangeably Both are a form of expiratory support Elevate baseline airway pressure CPAP Continuous Positive Airway Pressure Use term when no additional inspiratory support PEEP Positive End Expiratory Support Use term when providing inspiratory support

How Some Specific Ventilators work Theatre Ventilators

Generally these are volumecontrolled ventilators. Bag in bottle type ventilators Bag Squeezers Volume Cycled, Time Triggered, CMV mode. Modern ventilators allow Pressure Control, SIMV and PEEP Main advantage is guaranteed minute ventilation. Good in theatre where lung compliance affected by surgery

Bag in Bottle Expandable bag is enclosed in an airtight bottle. Injection or extraction of air in the bottle causes expansion and contraction of the bag Injection electronically controlled Electronic solenoid valves electromechanical valve for use with liquid or gas shut off, release, dose, distribute or mix fluids

Manley Ventilator Historical Interest 1952, Roger Manley, Westminster Hospital Most popular model used in Europe for 4 decades Gas driven, no electrical power, no explosion hazard Minute Volume divider Gas flow from anaesthetic machine used to lift a weighted bellows Falls under gravity, forcing gas into lungs. Inflation pressure varied by sliding movable weight on top of the bellows. The volume of gas delivered adjusted on curved slider restricts bellows excursion You can only set Vt and FGF (not RR) RR = FGF/ Vt

Penlon Nuffield Anaesthetic Ventilator Compressed gas Require high pressure Intermittent blower Uses Fluid Logic (coanda effect) Control unit with spool valve Patient valve - connects to circuit Newton Valve for paediatrics Pneupac child ventilators

Transport Ventilators Generally Volume Control Ventilators: Guaranteed Minute ventilation Good in transit if patient s tidal volumes are not being continuously monitored Volume Cycled, Time Triggered, CMV mode. Modern ventilators allow Pressure Control, SIMV and PEEP Small, Compact and Rugged Battery power supply Pneumatic supply (compressed gas) Intermittent blowers Earlier models fluidic logic controls Newer models electronic logic controls

ITU Ventilators High pressure generators Sophisticated multi-modal ventilators Microprocessor control Feedback mechanisms Pressure and flow transducers Record and regulated flows/ volumes delivered Electronic solenoid valves

Questions?