TREATMENT AN EDUCATIONAL SERIES BROUGHT TO YOU BY GILEAD SCIENCES

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PLANNING FOR TREATMENT AN EDUCATIONAL SERIES BROUGHT TO YOU BY GILEAD SCIENCES

ADVANCES IN HEP C TREATMENT LEARN MORE ABOUT HEP C There s never been a better time to treat Hep C. Recent scientific advances have led to shorter treatment options with average cure rates of around 95%. In the past few years, it s estimated that more people have been treated and cured of Hep C than in the previous decade. You are considered cured if the Hep C virus is not detected in your blood 3 months after your treatment is completed. It s important to work with your Hep C Specialist to plan your next steps before you begin treatment. If you have questions about what to expect or need help preparing for a conversation with your Hep C Specialist visit HEPCHOPE.COM to download a Hep C Specialist appointment guide or call to talk with a Hep C Educator. 3 5 7 9 11 13 Treatment Advances Preparing For Treatment What To Do Next After Treatment Hep C Resources Hep C Terms 15 Notes HEPCHOPE.COM

TREATMENT ADVANCES From 1991 until today there has been great progress in Hep C treatment. Scientific advances have led to shorter treatment options without the harsh side effects of interferon injections. Today s treatment options are highly effective and cure rates have significantly improved since 2011 with the addition of medicines called direct-acting antivirals (DAAs). DAAs are oral medicines that work against the virus to keep it from multiplying in the body. THERE HAS NEVER BEEN A BETTER TIME TO BE TREATED FOR HEP C, BECAUSE IT CAN BE CURED. TALK TO YOUR HEP C SPECIALIST ABOUT A TREATMENT PLAN TODAY. Today, more people with Hep C can be treated successfully with just oral therapy. 3 4 HEPCHOPE.COM

PREPARING FOR TREATMENT Because every patient s Hep C is unique, your Hep C Specialist will consider the factors below before you start treatment. These factors include: GENOTYPE The type of Hep C you have. Your Hep C Specialist will also consider your overall medical history, including: Other illnesses or conditions you may have, such as diabetes, heart disease, high blood pressure, or HIV All medicines and herbal supplements you are taking VIRAL LOAD The amount of the Hep C virus in your blood. TREATMENT HISTORY Any prior Hep C treatment you may have had. FIBROSIS SCORE The amount of damage to your liver. Getting your medicine Many new Hep C treatment options are considered specialty drugs and are not available at your local pharmacy. They are usually distributed through a specialty pharmacy a pharmacy that provides medications that have special delivery, storage, or administration requirements, and delivers medicine directly to patients by U.S. mail or a delivery service. 5 HEPCHOPE.COM 6

WHAT TO DO NEXT Talk to your Hep C Specialist about your plan moving forward. It s likely you will have questions for your Hep C Specialist as you consider treatment. Here are some you might start with: People who follow their treatment plan have a better chance of being cured. It s also important to keep all your appointments with your Hep C Specialist. And don t ever be afraid to ask questions. Do I need additional tests? Can my Hep C be cured? What are my treatment options? You can also learn more about Hep C and download a Hep C Specialist appointment guide at HEPCHOPE.COM or talk to a Hep C Educator at. When should I start treatment? Will there be any side effects? How do I get my medicine? How do I know if I m cured? 7 HEPCHOPE.COM 8

AFTER TREATMENT WHAT YOU NEED TO KNOW IF YOU GO THROUGH TREATMENT AND ARE CURED The Hep C antibody remains in your blood even after the infection goes away. Having antibodies is normal and does not mean you have Hep C. Once you have had Hep C, you will not be able to give blood. STAYING CURED The only way you can get re-infected with Hep C is if infected blood gets into your bloodstream. To help avoid this, follow these rules: Do not share personal items like razors or toothbrushes Do not inject drugs or share needles Do not have unprotected sex with an infected person Cure means the virus is not detected in the blood when measured 3 months after treatment is completed. SMART LIFESTYLE DECISIONS LIKE THESE CAN HELP YOU STAY CURED. 9 HEPCHOPE.COM 10

HEP C RESOURCES There is more to know about Hep C, and a lot of information is available online. Visit HEPCHOPE.COM to learn more about Hep C and how it may be time to see it in a new light. Hep C Hope offers information and resources that could help you move on from Hep C, including a Hep C Specialist appointment guide. Have questions? Call a Hep C Educator at. You also might check out sites like these*: HEPCHOPE.COM hcvadvocate.org hepatitis.va.gov help4hep.org cdc.gov/hepatitis/hcv/patienteduhcv.htm * These resources are independent third-party organizations and are unaffiliated with Gilead. 11 12

HEP C TERMS ANTIBODY A protein the body makes as it fights a virus. Antibodies show that you have been exposed to a virus at some time. CURE Cure is a medical term. You are considered cured when a lab test done 3 months after you ve completed treatment does not find any Hep C virus in your blood. DIRECT-ACTING ANTIVIRALS (DAAs) Oral medicines that work against the Hep C virus to keep it from multiplying inside the body. FIBROSIS Scarring in the liver. As Hep C progresses, scar tissue can replace healthy liver tissue. The liver might then stop working as well as it should. FIBROSIS SCORE (F-SCORE) A measure of just how damaged your liver is. INTERFERON (IFN) A type of protein produced by the body s natural defense system (immune system) in response to viral infection. It is given as an injection to help fight Hep C. LIVER Your body s second-largest organ. It weighs about 3 pounds. It is located under your rib cage on your right side. RIBAVIRIN (RBV) An antiviral medicine that became a standard part of Hep C treatment as of 1998. It is taken twice a day, orally, along with other medicines. It works to stop the Hep C virus from spreading in the body. VIRAL LOAD The amount of the Hep C virus in your blood. Your healthcare provider may test your blood before, during, and after treatment to find out your viral load. GENOTYPE The Hep C virus has at least 6 different types. They are called genotypes. Genotype 1 is the most common in the U.S. 13 HEPCHOPE.COM 14

NOTES NOTES 15 HEPCHOPE.COM 16

NOTES NOTES 17 HEPCHOPE.COM 18

HEP C HOPE, GILEAD and the GILEAD logo are trademarks of Gilead Sciences, Inc. All other trademarks referenced herein are the property of their respective owners. 2017 Gilead Sciences, Inc. All rights reserved. UNBC4357 02/17