SECTION 1: IDENTIFICATION OF THE SUBSTANCE OR MIXTURE AND OF THE SUPPLIER 1.1 Product Identifier Trade name: Product identifier: 4240-CYT-017 1.2 Relevant Identified Uses of the Substance or Mixture and Uses Advised Against Product use: Cytology fixative spray Uses advised against: All other uses 1.3 Details of the Supplier of the Safety Data Sheet Manufacturer/supplier: Innovatek Medical Inc. #3 1600 Derwent Way Delta, British Columbia V3M 6M5 Telephone: 604-522-8303 1.4 Emergency Telephone Number Emergency telephone (general information only): 604-522-8303 Business hours: 9:00 am to 5:00 pm Monday through Friday (PST) SECTION 2: HAZARDS IDENTIFICATION 2.1 Classification of the Substance or Mixture: Flammable liquid Category 2 Serious eye damage/eye irritation Category 2 Specific target organ toxicity (Single exposure) (Narcotic effects) Category 3 2.2 Label Elements Hazard pictograms: Hazard phrases: H225 Highly flammable liquid and vapour H319 Causes serious eye irritation H336 May cause drowsiness or dizziness Precautionary phrases: P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground/bond container and receiving equipment. P241 Use explosion-proof electrical/ventilating/lighting equipment. P242 Use only non-sparking tools. P243 Take precautionary measures against static discharge. P260 Do not breathe vapours. P261 Avoid breathing vapours. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves, protective clothing, and eye protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Page 1 of 5
P307 + P311 P370 + P378 P403 + P235 P405 P501 IF exposed: Call a POISON CENTER or doctor/physician. In case of fire: Use dry chemical, alcohol resistant foam, water fog, dry chemical, or carbon dioxide to extinguish. Store in a well ventilated place. Keep cool. Store locked up. Dispose of container to approved disposal site. 2.3 Other Hazards: None SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 3.1 Identities of Ingredients Common Chemical Name % CAS number Isopropanol 75-85 v/v 67-63-0 Polyethylene glycol (average m.w. = 1,500) SECTION 4: FIRST AID MEASURES 2-5 w/v 25322-68-3 Not applicable 4.1 Description of First Aid Measures General notes: No special measures required. CLP/GHS classification (1272/2008) Flammable liquid Category 2 Serious eye damage/eye irritation Category 2 Specific target organ toxicity (Single exposure) (Narcotic effects) Category 3 Inhalation: If affected, remove individual to fresh air, if breathing is difficult, administer oxygen, if breathing has stopped, give artificial respiration. Keep person warm, quiet and get medical attention. Skin contact: Thoroughly wash exposed area with soap and water. Remove contaminated clothing. If irritation develops get medical attention. Eye contact: Flush with large amounts of water for at least 15 minutes, lifting upper and lower lids occasionally, get medical attention. Ingestion: Do not induce vomiting, keep person warm and quiet give large amounts of water, never give anything by mouth to an unconscious person, and get medical attention immediately. 4.2 Most Important Symptoms and Effects, Both Acute and Delayed No further relevant information available. 4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed No further relevant information available. SECTION 5: FIREFIGHTING MEASURES 5.1 Extinguishing Media Suitable extinguishing media: Dry chemical, alcohol resistant foam, water fog, carbon dioxide Unsuitable extinguishing media: Water jet 5.2 Special Hazards Arising from the Substance or Mixture Hazardous combustion products: Carbon dioxide and carbon monoxide, various hydrocarbons Page 2 of 5
5.3 Advice for Firefighters: Self-contained breathing apparatus and protective clothing should be worn in fighting large fires involving chemicals. Determine the need to evacuate or isolate the area according to your local emergency plan. Use water spray to keep fire exposed containers cool. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1 Personal Precautions, Protective Equipment and Emergency Procedures Wear appropriate protective equipment. Eliminate all ignition sources and ventilate the area with explosion-proof equipment. Prevent entry into basements or confined areas. 6.2 Environmental Precautions: Prevent entry in storm sewers and waterways. Report spill as required by local and federal regulations. 6.3 Methods and Material for Containment and Cleaning Up Small spill: Absorb liquid on paper, vermiculite, floor absorbent, or other absorbent material. Large spill: Eliminate all ignition sources (flares, flames including pilot lights, electrical sparks). Persons not wearing protective equipment should be excluded from area or spill until clean-up has been completed. Stop spill at source, dike area of spill to prevent spreading, pump liquid to salvage tank. Remaining liquid may be taken up on sand, clay earth, floor absorbent, or other absorbent material and shovel into containers. 6.4 Reference to Other Sections See Section 7 for information on safe handling. See Section 8 for information on personal protection equipment. See Section 13 for disposal information. SECTION 7: HANDLING AND STORAGE 7.1 Precautions for Safe Handling: Use safety glasses and appropriate gloves 7.2 Conditions for Safe Storage, Including Any Incompatibilities Keep container tightly closed, store in a cool and well-ventilated area away from ignition source. Do not store near oxidizing materials. 7.3 Specific End Uses Industrial uses: None identified Professional uses: In vitro diagnostic SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1 Control Parameters Chemical name OSHA PEL ACGIH Isopropanol TWA: 400 ppm TWA: 200 ppm STEL: 400 ppm Polyethylene glycol TWA: 5 mg/m³ inhalation respirable TWA: 15 mg/m³ inhalation total TWA: 3 mg/m³ inhalation respirable TWA: 10 mg/m³ inhalation total Page 3 of 5
8.2 Exposure Controls Appropriate engineering controls: Provide sufficient mechanical (general and/or local exhaust) ventilation to maintain exposures below TWA. General protective and hygienic measures: Wash hands before breaks and at end of work. Personal protection equipment: Protection of hands: Wear resistant gloves (consult your safety equipment supplier) Eye/face protection: Chemical splash goggles in compliance with OSHA regulations are advised; however OSHA regulations also permit other type safety glasses (consult your safety equipment supplier) Body protection: Normal work clothing covering arms and legs SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 9.1 Information On Basic Physical and Chemical Properties Appearance: Colourless liquid ph: Not available Odour: Alcohol odour Vapour pressure: 33 mmhg Odour threshold: 28.2 ppm Vapour density (Air=1): 2.6 Melting point / freezing point: -89 C Solubility/miscibility in water: Insoluble Boiling point: 83 C Auto-ignition temperature: 399 C Flash point: 14 C (closed cup) Decomposition temperature: Evaporation rate: 2.5 Viscosity: Not established Flammability: Flammable Explosive properties: Flammability limit: Sensitivity to impact: Not available Upper: 12% Sensitivity to static discharge: Yes Lower: 2% Specific gravity: 0.78 SECTION 10: STABILITY AND REACTIVITY 10.1 Reactivity: Not reactive under normal conditions 10.2 Chemical Stability: Normally stable 10.3 Possibility of Hazardous Reactions: Reaction with strong oxidizers will generate heat and cause fires. 10.4 Conditions to Avoid: Avoid heat, static, spark and open flame 10.5 Incompatible Materials: Strong oxidizing agents, strong alkalis and strong mineral acids 10.6 Hazardous Decomposition Products: None SECTION 11: TOXICOLOGICAL INFORMATION 11.1 Information on Toxicological Effects Routes of entry: Skin contact/skin absorption, eye contact, inhalation & ingestion Effects of acute exposure to product: Eye contact: Can cause moderate irritation, redness, tearing Skin contact: Can cause irritation, defatting, dermatitis, burns Inhalation: Ingestion: Excessing inhalation of vapors can cause nasal and respiratory irritation and central nervous system effects including dizziness, weakness, fatigue, nausea, headache and possible unconsciousness Can cause gastrointestinal irritation, nausea, vomiting, narcosis, unconsciousness and diarrhea Page 4 of 5
Effects of chronic exposure to product: Eye contact: May cause corneal damage Skin contact: Prolonged or repeated contact can cause irritation, defatting, dermatitis, burns, possible sensitization Exposure limits (value, source, date): 500 ppm (as STEL) (ACGIH 1998) Acute toxicity: Isopropanol: LD50 oral rat 5045 mg/kg; LC50 rat 16,000 ppm/4 hr Polyethylene glycol: LD50 oral rat 30,200 mg/kg Irritancy: Skin, eye & inhalation Sensitization: Skin contact Teratogenicity: None identified Mutagenicity: None identified Synergistic products: None identified Carcinogenicity: None identified Reproductive toxicity: None identified SECTION 12: ECOLOGICAL INFORMATION SECTION 13: DISPOSAL CONSIDERATIONS SECTION 14: TRANSPORT INFORMATION SECTION 15: REGULATORY INFORMATION SECTION 16: OTHER INFORMATION 16.1 Preparation Information: Prepared by: Logistics Department Preparation date: May 6, 2015 Page 5 of 5