SenTec OxiVenT Illuminate Ventilation and Oxygenation PCO2 PO2. Digital Transcutaneous Blood Gas Monitoring

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Digital Transcutaneous Blood Gas Monitoring SenTec OxiVenT Illuminate Ventilation and Oxygenation MONTHS COMPLETE WARRANTY PCO2 PO2 Continuous Noninvasive Safe Easy to Use Accurate

OxiVenT overcoming limitations of arterial blood gases, etco2 and SpO2 monitoring Assessing ventilation and oxygenation in neonatal patients is a challenge. With the SenTec OxiVenT Sensor, a new generation of transcutaneous measurement technique overcomes the limitations of current methods and helps healthcare professionals to guide ventilation and oxygenation-related treatments in neonates For better patient outcomes where it matters most. Why SpO2 is not enough Due to the S-Shape of the 'oxyhemoglobin dissociation curve' (ODC) hyperoxemia/ hyperoxia cannot be detected by pulse oximetry (SpO2). Monitoring tcpo2 provides a crucial parameter to avoid the risk of hyperoxia and severe complications such as Retinopathy of Prematurity (ROP). % SpO2 100 Small change in PaO2 changes SpO2 60 Above approx. 100mmHg changes in PaO2 do not cause (significant) Sp02 changes. SpO2 cannot detect PaO2 changes in the hyperoxic range! 100 700 PaO2 [mmhg] Arterial Blood Gas sampling Provides only a snapshot every few hours and bears the risk of invasiveness, especially in neonatal patients. Room Air Breathing (FiO2=21%) avg. alveolar PO2 = 100mmHg PaO2 PawO2 EtCO2 Monitoring Is sometimes inefficient in patients with small tidal volumes and inapplicable in certain ventilation modes such as HFO.

Dedicated to neonatal needs SenTec's revolutionary OxiVenT Sensor featuring optical tcpo2 combined with state-of-the-art tcpco2 technique provides continuous and accurate feedback on ventilation and oxygenation changes. Different display options: tcpco2, tcpo2 and heating power trends Baseline and Delta values Two different SenTec TC Sensors 1 connectable: V-Sign Sensor: PCO2 measured by Stow-Severinghaus type PCO2 sensor reliable and safe clinically trusted for more than 10 years OxiVenT Sensor: PCO2 PO2 tcpo2 measured by dynamic fluorescence quenching virtually drift free high accuracy 1 For pediatric & adult patients additional SpO2 & Pulse Rate available in the same Sensor.

Set baseline and markers Set a baseline just before changing the treatment to assess the impact on the patient's ventilation and oxygenation. User profiles Quickly adapt settings to your needs: select individually customized profiles stored on the monitor. Select from multiple recommended measurement sites Trendlines allow early detection of ventilation and oxygenation changes Estimates of PaCO2 and PaO2 in trendline, baselines, and delta values. Relative Heating Power (RHP) shows the required heating power to keep the Sensor at set temperature. Changes of RHP may be attributable to changes in perfusion. Delta values Numerical indication of the difference between the current reading and the reading from the set Baseline and 10 min before.

Effective and efficient monitoring Save your time for the important tasks SmartCalMem Disconnect the Sensor (e.g. to untangle cables or to move the patient) without removing the Sensor from the patient. No need to recalibrate the Sensor when re-connecting. Automatic calibration management Simply store the Sensor in the Docking Station calibration is fully automatic. Within a few minutes Ready for Use status is established and maintained until patient application. Easy maintenance One simple tool to perform the membrane change. Membrane life up to 42 days. Transportable Lightweight, dedicated mounting plates / roll stands, battery life up to 10 hours.

Sensor is freely rotatable Excellent accuracy O2 set 02 OxiVenT O2 Clark Electrode 100 70 90 60 80 po2 [mmhg] 70 60 PtcCO2 [mmhg] 50 40 50 30 40 30 0 10 20 30 40 50 60 70 time [min] In Vitro performance test of the SenTec OxiVenT tcpo2 compared to a clark type electrode demonstrates higher accuracy [internal data]. 20 20 40 60 80 PaCO2 [mmhg] Comparison between tcpco2 measured with the SenTec Digital Monitoring System and arterial carbon dioxide in neonatal patients [Rowley] shows high correlation and accuracy*. Safe sensor temperature and site time management Redundant sensor temperature controls to avoid the risk of skin irritations. Automatic, institution-restrictable site time control and site inspection intervals. Automatic sensor temperature reduction if site time has elapsed and site inspection is missed. Safety-relevant parameters are password protected. A low Sensor temperature of 41 C (tcpco2) and 43 C (tcpo2) is recommended in neonatal patients. Automatic artifact detection Automatic data quality verification and artifact detection. * Poster presentation at AARC in 2008: Daniel D. Rowley et al, Charlottesville, Virginia, U.S.A. Also refer to Storre JH, Magnet FS, Dreher M, Windisch W. Transcutaneous monitoring as a replacement for arterial PCO2 monitoring during nocturnal non-invasive ventilation. Respir Med 2011;105:143 150.

Reliable and safe Best signal quality Digital Sensor with integrated CPU. Measured signals are digitized and preanalyzed in the Sensor head for the best signal quality. Multi Site Attachment Rings (MAR) The design enables a gentle sensor application and a smooth removal without damaging the sensitive skin. e.g. Dräger, Philips and EMR Connectivity / Data Management Direct connectivity to Patient Monitoring Systems. Clinically trusted Clinical usage of over 1000 SDMS with V-Sign in neonatal units and over 2000 SDMS in pediatric / adult units around the world.

RF-007710-a Continuous and noninvasive monitoring of tcpo2 and tcpco2 supports the therapy guiding in Neonates in noninvasive ventilation HFO / HFJV ventilation volume-targeted ventilation volume-limited ventilation lung recruitment oxygen titration weaning from mechanical ventilation decision to (re-)intubate or extubate Contact SenTec in Switzerland or our worldwide distribution partners. www.sentec.ch/contact SenTec AG Ringstrasse 39 CH-4106 Therwil Switzerland +41 61 726 97 60 www.sentec.ch Your local distributor: