SAFETY DATA SHEET Product Name: Catalog Number: 1. PRODUCT IDENTIFICATION HEPES Buffer Solution (1M) B351xx Recommended Use: For in vitro research use only Company: Atlanta Biologicals, Inc. 4172 Industry Way Flowery Branch, GA 30542 Telephone Number: 1-800-780-7788 Emergency Telephone Number: 1-800-780-7788 2. HAZARDS IDENTIFICATION GHS Classification Not a hazardous substance or mixture. GHS Label Elements (Including precautionary statements) Not a hazardous substance or mixture. Hazards not Otherwise Classified (HNOC) or not covered by GHS None 3. COMPOSITION/INFORMATION ON INGREDIENTS No ingredients are hazardous according to OSHA criteria. No components need to be disclosed according to the applicable regulations. 4. FIRST AID MEASURES If inhaled: If breathed in, move person into fresh air. If not breathing give artificial respiration. In case of skin contact: Wash off with soap and plenty of water. In case of eye contact: Flush eyes with water as a precaution. If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water. Most Important Symptoms and Effects, both Acute and Delayed The most important known symptoms and effects are described in the labeling section (section 2) and/or in section 11. Indication of any Immediate Medical Attention and Special Treatment Needed 5. FIRE FIGHTING MEASURES Suitable Extinguishing Media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides, sulfur oxides Special Protective Equipment for Firefighters Wear self-contained breathing apparatus for firefighting if necessary. Page 1 of 5
6. ACCIDENTAL RELEASE MEASURES Personal Precautions Use personal protective equipment described in section 8. Avoid breathing vapors, mist or gas. Containment and Clean-Up Methods Keep in suitable, closed containers for disposal. Environmental Precautions Do not let product enter drains. 7. HANDLING AND STORAGE Precautions for Safe Handling For precautions see section 2. Conditions for Safe Storage Keep container tightly closed in a dry and well-ventilated place. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Contains no substance(s) with occupational exposure limit values. Appropriate Engineering Controls General industrial hygiene practice. Personal Protective Equipment Eye/Face protection: Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US). Skin protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. Body protection: Impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection: Respiratory protection not required. For nuisance exposures use type OV/AG (US) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US). 9. PHYSICAL AND CHEMICAL PROPERTIES Physical Properties Appearance: Odor: Odor threshold: Chemical Properties ph: Melting point/freezing point: Initial boiling point and boiling range: Flash point: Evaporation rate: Flammability (solid, gas): Upper/lower flammability or explosion limits: Liquid Page 2 of 5
Vapor pressure: Vapor density: Relative density: Solubility: Partition coefficient (n-octanol/water): Auto-ignition temperature: Decomposition temperature: Viscosity: Reactivity Chemical Stability Stable under recommended storage conditions. Possibility of Hazardous Reactions Conditions to Avoid Incompatible Materials Strong oxidizing agents Hazardous Decomposition Products In the event of fire, see Section 5. Acute Toxicity Inhalation: Dermal LD50: Skin Corrosion/Irritation Serious Eye Damage/Eye Irritation Respiratory or Skin Sensitization Germ Cell Mutagenicity 10. STABILITY AND REACTIVITY 11. TOXICOLOGICAL INFORMATION Chronic Toxicity IARC: No component of this product is present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. ACGIH: No component of this product is present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. NTP: No component of this product is present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. OSHA: No component of this product is present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Reproductive Toxicity Page 3 of 5
Specific Target Organ Toxicity - Single Exposure Specific Target Organ Toxicity - Repeated Exposure Aspiration Hazard Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical and toxicological properties have not been thoroughly investigated. 12. ECOLOGICAL INFORMATION 13. DISPOSAL CONSIDERATIONS Observe all federal, state and local environmental regulations Not dangerous goods 14. TRANSPORT INFORMATION 15. REGULATORY INFORMATION SARA 302 Components No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components The material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313. SARA 311/312 Hazards No SARA hazards Massachusetts Right To Know Components No components are subject to the Massachusetts Right To Know Act. Pennsylvania Right To Know Components Component CAS No. Revision Date 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid 7365-45-9 Water 7732-18-5 New Jersey Right To Know Components Component CAS No. Revision Date 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid 7365-45-9 Water 7732-18-5 California Prop. 65 Components This product does not contain any chemicals known to State of California to cause cancer, birth defects or any other reproductive harm. Page 4 of 5
16. OTHER INFORMATION HMIS Classification Health Hazard: 0 Flammability: 0 Physical Hazards: 0 NFPA Classification Health Hazard: 0 Flammability: 0 Physical Hazards: 0 Preparation Date: August 2014 Version Number: 0.0 The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Atlanta Biologicals shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. Page 5 of 5