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Noticias News Nouvelles The Centre for Mother, Infant, and Child Research Sunnybrook Health Sciences Centre C8-2075 Bayview Avenue, Toronto ON CANADA M4N 3M5 Tel: 1 416 480 5639 Fax: 1 416 480 5633 email: tbs@sw.ca website: www.cmicr.ca V O L U M E 1 0, I S S U E 3 M A R C H 3 1, 2 0 1 1 Total: 2800!!! Total in March: 42 Recruitment Complete! INSIDE THIS ISSUE Recruitment Complete Thank you messages 1 2 On April 1st we reached our recruitment goal!! Recruitment is now closed! We could not have reached this milestone without your continued dedication and commitment to the study. Congratulations to everyone on a job well done! Data Campaign 3 Reminder: Ethics approvals Special Recognition Recruitment Excellence 3 4 4 Recruitment Table 5 2yr Table 8

PAGE Message from Jon Barrett Dear friends, It is with many emotions that I write this note. The first are gratitude and humility to all of you who have made this momentous day possible. None of this could have happened without you! And from all those at CMICR and me personally, a huge THANK YOU. There is just a little sadness because it means we are at the end of a chapter which has allowed us to become like a family. The third is a lot of pride in our achievement; together we have successfully completed a landmark piece of scientific work--the impact of this work will outlive all of us! Finally, I am sure we share the excitement as we get all the data returned to us to be analyzed. We hope to see you all at the final results meeting next year! From all of us at CMICR: 2

PAGE 3 RECRUITMENT IS FINISHED! PLEASE SEND US YOUR DATA TODAY! Data Campaign Please send all outstanding data, unanswered queries, and overdue supporting documents, to the Data Coordinating Centre today! If you expect delays, please contact us by email as soon as possible to let us know. Reminder: Ethics Renewals Although the Twin Birth Study is now closed for recruitment, we still have to complete the 2 year follow-up phase of the study. As a result, we still need to have a copy of your current ethics approval at the Data Coordinating Centre. Please continue to submit the protocol to your local Research Ethics Board for renewal when it is due, and send a copy of the approval letter to us. Thank you for your cooperation with this.

PAGE 4 Special Recognition We wish to acknowledge Dr Maria De la Calle and the team at Hospital La Paz in Madrid, Spain for recruiting the 2800th patient into the study!! Recruitment Excellence Congratulations to Dr Mario Palermo and the team at Hospital Posadas, Buenos Aires, Argentina; Dr Raquel de Lourdes Martin and the team at Hospital LC Lagomaggiore, Mendoza, Argentina; Dr Raul Abalos Gorostiaga and the team at Hospital Ramon Carrillo, Santiago del Estero, Argentina; Dr Renato Augusto Moreira de Sa and the team at Maternidade Escola da UFRJ, Rio de Janeiro, Brazil; Dr Jose Guillherme Cecatti and the team at University of Campinas, Campinas, Brazil; Dr Mordechai Hallak and the team at Hillel Yaffe Medical Center, Hadera, Israel; Dr Dalia Mansour-Schwake and the team at Holy Family Hospital, Nazareth, Israel; Dr Maria de la Calle and the team at Hospital La Paz, Madrid, Spain and Mr Kim Hinshaw and the team at City Hospitals Sunderland NHS Foundation Trust, Sunderland, UK. Keep up the excellent work! We will be sending a gold seal to place on your Certificate of Achievement. Happiness lies in the joy of achievement and the thrill of creative effort. ~Theodore Roosevelt

P A G E 5 Twin Birth Study Recruitment (Projected sample size of 2800) March 31, 2011 Annual Jun Jul - Jan Feb Mar Grand Goal 2003 2004 2005 2006 2007 2008 2009 2010 2010 2011 2011 2011 Total COUNTRY ARGENTINA 67 60 65 96 107 122 125 63 60 9 13 9 729 BRAZIL 73 2 44 71 54 63 97 43 26 7 3 4 414 CANADA 84 3 25 53 46 41 29 40 7 9 1 3 3 260 ISRAEL 46 21 27 16 14 32 42 20 19 1 5 4 201 POLAND 15 4 28 18 44 35 25 10 1 2 167 UK 68 2 2 15 18 16 31 19 11 4 4 4 126 CHILE 16 8 11 13 8 16 25 13 7 4 3 6 114 SPAIN 32 2 6 10 9 8 7 10 39 8 5 3 107 EGYPT 20 19 14 15 6 12 20 3 89 AUSTRALIA 32 2 15 12 17 14 8 8 2 1 79 THE NETHERLANDS 10 7 9 17 6 6 5 4 9 63 SERBIA 11 27 24 4 2 1 58 USA 31 4 13 10 8 5 11 3 3 57 JORDAN 9 5 5 8 9 8 6 7 7 1 56 JAMAICA 4 23 14 7 5 3 2 54 ESTONIA 3 5 12 8 7 7 7 5 2 53 QATAR 22 10 25 3 2 2 42 HUNGARY 4 5 11 6 3 5 5 2 1 1 39 OMAN 7 9 8 2 1 20 ROMANIA 3 2 5 2 4 3 1 1 18 BELGIUM 0 5 7 3 15 GERMANY 9 3 4 4 3 1 15 URUGUAY 13 4 3 3 10 CROATIA 0 4 3 2 9 GREECE 0 1 3 4 Total 579 3 182 333 373 385 425 487 245 238 43 43 42 2799 CENTRES BY COUNTRY (Shaded area is prior to start-up) ARGENTINA Hospital LC Lagomaggiore, Mendoza 12 31 32 27 22 25 26 10 14 2 2 3 194 Hospital Ramon Carrillo, Santiago del Estero 10 2 15 19 28 36 13 14 6 6 1 140 Hospital Posadas, Buenos Aires 6 22 28 17 19 6 15 8 3 1 2 121 Hospital Avellaneda, Tucuman 6 2 11 13 13 10 9 11 1 70 Hospital JR Vidal, Corrientes 6 4 10 18 14 9 7 1 1 64 Hospital Sarda, Buenos Aires 10 3 5 11 11 5 4 1 2 42 Hospital Penna, Bahia Blanca 4 12 10 6 3 5 4 40 Hospital Angela Iglesia de Llano, Corrientes 3 5 9 2 2 3 21 Hospital Juan A Fernandez, Buenos Aires 4 12 2 14 Hospital Alvarez, Buenos Aires 2 1 6 1 8 Hospital JM Cullen, Santa Fe 4 3 2 5 Centre(s) that are no longer recruiting 0 10 BRAZIL University of Campinas, Campinas 5 2 17 15 17 13 16 6 3 2 91 Maternidade Escola da UFRJ, Rio de Janeiro 6 8 16 18 14 15 7 5 5 1 1 90 University of Pernambuco, Recife 7 13 14 10 17 2 56 Maternidade Escola de Vila Nova Cachoeirinha, Sao Paulo 8 18 10 9 1 38 Hospital Universitario de Jundiai, Jundiai 5 22 4 1 27 Hospital Sao Lucas, Porto Alegre 5 5 11 9 1 1 27 Hospital Universitario Antonio Pedro, Niteroi 5 1 10 5 2 2 2 3 25 Perinatal, Rio de Janeiro 8 8 3 1 2 2 1 17 ISCMPA-Maternidade Mario Totta, Porto Alegre 6 5 4 3 1 13 Botucatu Medical School, Botucatu 2 4 4 2 1 1 12 Hospital Materno Infantil, Goiania 3 2 4 2 1 1 10 Hospital das Clinicas da UFPE, Recife 5 4 1 2 7 Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 8 1 1

P A G E 6 Annual Jun Jul - Jan Feb Mar Grand Goal 2003 2004 2005 2006 2007 2008 2009 2010 2010 2011 2011 2011 Total CANADA Sunnybrook Health Sciences Centre, Toronto 5 3 14 11 13 18 8 9 4 1 1 1 1 84 IWK Health Centre, Halifax 7 1 4 6 4 6 6 2 29 Regina General Hospital, Regina 5 5 7 3 2 6 1 1 25 Trillium Health Centre, Mississauga 6 6 4 6 1 17 Lion's Gate Hospital, Vancouver 3 6 1 2 2 1 2 1 1 16 St Joseph's Health Care, London 9 1 6 1 1 1 10 Foothills Medical Centre, Calgary 7 1 5 1 1 1 9 SMBD Jewish General Hospital, Montreal 6 2 4 2 8 Royal University Hospital, Saskatoon 6 4 1 1 6 North Bay General Hospital, North Bay 2 5 1 6 Royal Columbian Hospital, New Westminster 5 3 3 6 Toronto East General, Toronto 5 1 1 1 3 4 1 2 3 Children's & Women's Health Centre of BC, Vancouver 11 1 1 St Paul's Hospital, Vancouver 3 1 1 Centre(s) that are no longer recruiting 0 36 ISRAEL Nazareth Hospital (EMMS), Nazareth 3 18 19 10 7 3 57 Ma'ayney HaYeshua Medical Center, Bnei Brak 10 5 4 5 4 5 8 2 1 1 35 Edith Wolfson Medical Center, Holon 5 11 6 6 4 2 2 31 Holy Family Hospital, Nazareth 3 10 5 10 1 1 3 30 HaEmek Medical Center, Afula 7 1 7 2 2 1 13 Poriya Government Hospital, Tiberias 4 3 3 1 4 1 12 Hillel Yaffe Medical Center, Hadera 6 3 3 2 2 1 1 12 Bnai Zion Medical Center, Haifa 8 4 7 11 POLAND University School of Medical Sciences, Poznan 8 3 24 15 33 26 22 7 1 2 133 Polish Mother's Memorial Hospital, Lodz 5 1 2 10 8 2 3 26 Medical University of Gdansk, Gdansk 2 1 3 1 1 1 1 8 UK Bradford Royal Infirmary, Bradford 8 8 4 2 15 3 3 1 1 37 Nottingham City Hospital, Nottingham 9 2 2 3 2 7 1 6 1 1 1 26 Basildon & Thurrock University Hospital, Basildon 6 1 5 3 2 1 1 1 14 Liverpool Women's Hospital, Liverpool 12 6 4 2 12 Derriford Hospital, Plymouth 6 1 2 2 3 3 1 12 Queen's Medical Centre, Nottingham 6 6 1 1 8 City Hospitals Sunderland NHS Foundation Trust, Sunderland 5 1 1 1 2 5 Queen Elizabeth Hospital, King's Lynn 3 3 2 5 University Hospital of North Staffordshire, Stoke-on-Trent 8 3 1 4 Lewisham Hospital, London 5 3 3 CHILE Hospital Dr Gustavo Fricke, Vina del Mar 5 8 11 8 6 12 11 9 5 1 2 73 Hospital Dr Sotero del Rio, Puente Alto 11 5 2 4 14 4 2 4 2 4 41 SPAIN Hospital Clinic-University of Barcelona, Barcelona 5 2 6 10 9 8 7 4 5 1 52 Hospital La Paz, Madrid 15 1 21 4 2 3 31 Hospital Vall d'hebron, Barcelona 5 3 9 2 2 16 Complejo Hospitalario de Toledo, Toledo 7 2 4 1 1 8 EGYPT Assiut University Hospital, Assiut 20 19 14 15 6 12 20 3 89 AUSTRALIA Ipswich Hospital, Ipswich 3 1 12 9 1 3 1 1 28 Mater Mothers' Hospital, Brisbane 6 2 3 3 1 6 4 1 20 St George Hospital, Sydney 3 2 5 1 3 1 12 Toowoomba Base Hospital, Toowoomba 2 4 2 6 Monash Medical Centre, Clayton 4 4 1 5 Logan Hospital, Meadowbrook 5 3 1 4 Women's and Children's Hospital, Adelaide 6 1 1 2 Townsville Hospital, Townsville 3 1 1 2 THE NETHERLANDS Atrium Medical Center, Heerlen 3 4 5 7 5 6 2 1 4 34 Academisch Ziekenhuis Maastricht, Maastricht 2 3 2 1 1 1 2 10 Maxima Medical Centre, Veldhoven 3 2 2 3 7 Sint Lucas Andreas Ziekenhuis, Amsterdam 2 4 1 5 Centre(s) that are no longer recruiting 0 7

P A G E 7 Annual Goal Jul - Jun Jan Feb Mar Grand 2003 2004 2005 2006 2007 2008 2009 2010 2010 2011 2011 2011 Total SERBIA University of Belgrade, Belgrade 11 27 24 4 2 1 58 USA East Bay Perinatal Medical Associates, Oakland 7 9 5 4 1 2 1 22 Maricopa Medical Center, Phoenix 8 3 3 2 1 1 2 12 University of Miami, Miami 9 1 10 11 University of South Carolina, Columbia 4 1 2 3 6 University of Iowa Hospitals and Clinics, Iowa City 3 1 1 2 Centre(s) that are no longer recruiting 0 4 JORDAN Islamic Hospital, Amman 9 5 5 8 9 8 6 7 7 1 56 JAMAICA University Hospital of the West Indies, Kingston 4 23 14 7 5 3 2 54 ESTONIA Tartu University Hospital - Women's Clinic, Tartu 3 5 12 8 7 7 7 5 2 53 QATAR Hamad Medical Corporation, Doha 22 10 25 3 2 2 42 HUNGARY University of Debrecen, Debrecen 4 5 11 6 3 5 5 2 1 1 39 OMAN Khoula Hospital, Muscat 7 9 8 2 1 20 ROMANIA University of Pharmacy and Medicine, Cluj-Napoca 3 2 5 2 4 3 1 1 18 BELGIUM Centre(s) that are no longer recruiting 0 15 GERMANY Ludwig Maximilians University of Munich, Munich 2 1 4 3 1 9 CUB - Virchow Klinikum, Berlin 5 3 3 CUB - Benjamin Franklin, Berlin 2 2 1 3 URUGUAY Pereira Rossell Hospital, Montevideo 13 4 3 3 10 CROATIA Centre(s) that are no longer recruiting 0 9 GREECE Centre(s) that are no longer recruiting 0 4 Centres awaiting first patient: [COUNTRY: Hospital, City (annual goal)] [month/year start-up package sent] UK: AberdeenMaternity,Aberdeen (6) [11/06];

P A G E 8 TBS 2 Year Follow-up The status of the TBS 2 Year Follow-up is displayed in the following table for centres that recruited patients. Centres arelistedaccordingtothetotal number of recruits by country andcentre. Seebelowfor thenumber of follow-up assessments performed by your centre! Let's aim for 100% follow-up!! Status 2003 2004 2005 2006 2007 2008 2009 2010 2011 Totals As of March 2011 COUNTRY ARGENTINA 60 51 65 58 96 87 107 100 122 90 125 7 123 31 729 393 BRAZIL 2 2 44 36 71 56 54 34 63 34 97 69 14 414 162 CANADA 3 3 25 22 53 47 46 37 41 33 29 25 40 4 16 7 260 171 ISRAEL 21 21 27 23 16 16 14 14 32 28 42 1 39 10 201 103 POLAND 4 4 28 26 18 15 44 34 35 21 25 10 3 167 100 UK 2 2 2 2 15 6 18 13 16 9 31 30 12 126 32 CHILE 8 8 11 11 13 13 8 7 16 12 25 3 20 13 114 54 SPAIN 2 2 6 6 10 10 9 9 8 8 7 2 49 16 107 37 EGYPT 19 19 14 14 15 15 6 6 12 1 20 3 89 55 AUSTRALIA 2 2 15 10 12 7 17 16 14 12 8 10 1 79 47 THE NETHERLANDS 7 7 9 9 17 14 6 5 6 6 5 1 13 63 42 SERBIA 27 21 24 4 6 1 58 25 USA 4 2 13 8 10 3 8 5 5 3 11 6 57 21 JORDAN 5 5 5 5 8 8 9 9 8 8 6 14 1 56 35 JAMAICA 23 16 14 5 7 8 2 54 21 ESTONIA 5 5 12 12 8 8 7 7 7 7 7 1 7 53 40 QATAR 35 7 42 HUNGARY 5 5 11 9 6 6 3 3 5 1 5 3 1 39 24 OMAN 17 3 20 ROMANIA 2 2 5 5 2 2 4 4 3 3 1 1 18 16 GERMANY 3 2 4 4 4 2 3 1 15 8 BELGIUM 5 4 7 7 3 2 15 13 URUGUAY 4 6 10 CROATIA 4 4 3 2 2 2 9 8 GREECE 1 3 4 Total 3 3 182 167 333 292 373 311 385 317 425 294 487 23 483 128 2799 1407 100.0% 91.8% 87.7% 83.4% 82.3% 69.2% 4.7% 50% CENTRES BY COUNTRY (Shaded area is prior to start-up) ARGENTINA Hospital LC Lagomaggiore, Mendoza 31 27 32 31 27 27 22 22 25 25 26 2 24 7 194 134 Hospital Ramon Carrillo, Santiago del Estero 2 2 15 15 19 19 28 28 36 3 27 13 140 67 Hospital Posadas, Buenos Aires 22 22 28 23 17 17 19 18 6 6 15 2 11 3 121 88 Hospital Avellaneda, Tucuman 2 2 11 11 13 12 13 13 10 20 1 70 38 Hospital JR Vidal, Corrientes 4 4 10 6 18 14 16 2 64 10 Hospital Sarda, Buenos Aires 3 5 5 11 11 11 9 3 42 16 Hospital Penna, Bahia Blanca 12 9 10 9 6 5 3 9 40 23 Hospital Angela Iglesia de Llano, Corrientes 5 4 9 9 2 2 2 3 21 15 Hospital Juan A Fernandez, Buenos Aires 12 2 14 Hospital Ramos Mejia, Buenos Aires 7 2 1 2 10 2 Hospital Alvarez, Buenos Aires 1 6 1 8 Hospital JM Cullen, Santa Fe 3 2 5 BRAZIL University of Campinas, Campinas 2 2 17 11 15 6 17 2 13 5 16 9 2 91 26 Maternidade Escola da UFRJ, Rio de Janeiro 8 8 16 15 18 18 14 10 15 12 7 90 51 University of Pernambuco, Recife 13 12 14 13 10 9 17 12 2 56 46 Maternidade Escola de Vila Nova Cachoeirinha, Sao Paulo 18 19 1 38 Hospital Universitario de Jundiai, Jundiai 22 5 27 Hospital Sao Lucas, Porto Alegre 5 11 10 1 27 Hospital Universitario Antonio Pedro, Niteroi 1 1 10 10 5 4 2 2 2 5 25 17 Perinatal, Rio de Janeiro 8 8 3 1 1 2 3 17 9 ISCMPA-Maternidade Mario Totta, Porto Alegre 5 4 4 4 3 3 1 13 11 Botucatu Medical School, Botucatu 4 4 3 1 12 Hospital Materno Infantil, Goiania 2 2 4 2 2 10 2 Hospital das Clinicas da UFPE, Recife 4 1 2 7 Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 1 1 CANADA Sunnybrook Health Sciences Centre, Toronto 3 3 14 14 11 10 13 12 18 17 8 7 9 5 3 84 63 IWK Health Centre, Halifax 1 1 4 4 6 6 4 4 6 6 6 2 2 29 23 McMaster University Medical Centre, Hamilton 10 10 7 7 4 4 4 4 25 25 Regina General Hospital, Regina 5 4 7 7 3 2 2 2 6 1 1 1 25 16 Trillium Health Centre, Mississauga 6 4 4 6 3 1 17 7 Lion's Gate Hospital, Vancouver 6 6 1 1 2 2 2 3 2 16 9 St Joseph's Health Care, London 1 1 6 2 1 10 1 Mount Sinai Hospital, Toronto 5 3 2 1 3 3 10 7 Foothills Medical Centre, Calgary 1 1 5 4 1 1 1 1 1 9 7 SMBD Jewish General Hospital, Montreal 2 4 1 2 8 1 North Bay General Hospital, North Bay 5 1 1 6 1 Royal University Hospital, Saskatoon 4 1 1 1 6 1 Royal Columbian Hospital, New Westminster 3 3 3 3 6 6 Toronto East General, Toronto 1 1 1 1 3 1 1 1 2 2 3 3 Children's & Women's Health Centre of BC, Vancouver 1 1 York Central Hospital, Richmond Hill 1 1 St Paul's Hospital, Vancouver 1 1 ISRAEL Nazareth Hospital (EMMS), Nazareth 18 17 19 1 17 3 57 18 Ma'ayney HaYeshua Medical Center, Bnei Brak 5 5 4 4 5 5 4 4 5 5 8 3 1 35 23 Edith Wolfson Medical Center, Holon 11 11 6 6 6 6 4 4 2 2 2 31 29 Holy Family Hospital, Nazareth 10 15 5 30 HaEmek Medical Center, Afula 1 1 7 6 2 2 2 2 1 13 11 Poriya Government Hospital, Tiberias 3 3 3 1 1 4 2 1 12 6 Hillel Yaffe Medical Center, Hadera 3 3 3 2 2 3 1 12 5 Bnai Zion Medical Center, Haifa 4 4 7 7 11 11 POLAND Univ School of Medicine, Poznan 3 3 24 24 15 14 33 33 26 21 22 7 3 133 95 Polish Mother's Memorial Hospital, Lodz 1 2 10 8 2 3 26 Medical University of Gdansk, Gdansk 1 1 3 2 1 1 1 1 1 1 8 5

P A G E 9 Status 2003 2004 2005 2006 2007 2008 2009 2010 2011 Totals As of March 2011 UK Bradford Royal Infirmary, Bradford 8 4 4 3 2 1 15 6 2 37 8 Nottingham City Hospital, Nottingham 2 2 2 2 3 2 2 2 7 4 1 7 2 26 12 Basildon & Thurrock University Hospital, Basildon 1 5 5 3 1 3 2 14 6 Liverpool Women's Hospital, Liverpool 6 6 12 Derriford Hospital, Plymouth 1 1 2 2 2 6 1 12 3 Queen's Medical Centre, Nottingham 6 1 1 8 City Hospitals Sunderland NHS Foundation Trust, Sunderland 1 4 5 Queen Elizabeth Hospital, King's Lynn 3 2 2 1 5 3 University Hospital of North Staffordshire, Stoke-on-Trent 3 1 4 Lewisham Hospital, London 3 3 CHILE Hospital Dr Gustavo Fricke, Vina del Mar 8 8 11 11 8 8 6 6 12 11 11 2 14 3 73 46 Hospital Dr Sotero del Rio, Puente Alto 5 5 2 1 4 1 14 1 6 10 41 8 SPAIN Hospital Clinic-University of Barcelona, Barcelona 2 2 6 6 10 10 9 9 8 8 7 2 9 1 52 37 Hospital La Paz, Madrid 22 9 31 Hospital Vall d'hebron, Barcelona 12 4 16 Complejo Hospitalario de Toledo, Toledo 6 2 8 EGYPT Assiut University Hospital, Assiut 19 19 14 14 15 15 6 6 12 1 20 3 89 55 AUSTRALIA Ipswich Hospital, Ipswich 1 1 12 12 9 8 1 4 1 28 21 Mater Mothers' Hospital, Brisbane 2 2 3 2 3 3 1 6 5 20 7 St George Hospital, Sydney 2 2 5 5 1 1 3 3 1 12 11 Toowoomba Base Hospital, Toowoomba 4 1 2 6 1 Monash Medical Centre, Clayton 4 2 1 5 2 Logan Hospital, Meadowbrook 3 1 1 1 4 2 Women's and Children's Hospital, Adelaide 1 1 1 2 1 Townsville Hospital, Townsville 1 1 1 1 2 2 THE NETHERLANDS Atrium Medical Center, Heerlen 4 4 5 5 7 7 5 4 6 6 2 1 5 34 27 Academisch Ziekenhuis Maastricht, Maastricht 3 3 2 2 1 1 3 10 5 Maxima Medical Centre, Veldhoven 2 5 7 Maaslandziekenhuis Sittard, Sittard 2 2 5 5 7 7 Sint Lucas Andreas Ziekenhuis, Amsterdam 4 2 1 1 5 3 SERBIA University of Belgrade, Belgrade 27 21 24 4 6 1 58 25 USA East Bay Perinatal Medical Associates, Oakland 9 5 5 1 4 1 1 3 22 7 Maricopa Medical Center, Phoenix 3 2 3 2 2 1 3 12 4 University of Miami, Miami 1 10 11 University of South Carolina, Columbia 1 1 2 2 3 3 6 6 Jamaica Hospital Medical Center, Jamaica 2 2 2 2 Texas Tech UHSC, Lubbock 2 2 University of Iowa Hospitals and Clinics, Iowa City 1 1 1 1 2 2 JORDAN Islamic Hospital, Amman 5 5 5 5 8 8 9 9 8 8 6 14 1 56 35 JAMAICA University Hospital of the West Indies, Kingston 23 16 14 5 7 8 2 54 21 ESTONIA Tartu University Hospital - Women's Clinic, Tartu 5 5 12 12 8 8 7 7 7 7 7 1 7 53 40 QATAR Hamad Medical Corporation, Doha 35 7 42 HUNGARY University of Debrecen, Debrecen 5 5 11 9 6 6 3 3 5 1 5 3 1 39 24 OMAN Khoula Hospital, Muscat 17 3 20 ROMANIA University of Pharmacy and Medicine, Cluj-Napoca 2 2 5 5 2 2 4 4 3 3 1 1 18 16 GERMANY Ludwig Maximilians University of Munich, Munich 1 1 4 4 3 2 1 9 7 CUB - Virchow Klinikum, Berlin 3 3 CUB - Benjamin Franklin, Berlin 2 1 1 3 1 BELGIUM Vrije Universiteit Brussel, Brussels 5 4 7 7 3 2 15 13 URUGUAY Pereira Rossell Hospital, Montevideo 4 6 10 CROATIA Sveti Duh Hospital, Zagreb 4 4 3 2 2 2 9 8 GREECE Alexandra Maternity, Athens 1 3 4