Page 1 of 8 1 CHEMICAL PRODUCT AND COMPANY INFORMATION Product Description CHLOROFORM-D "100%" (D, 99.96%) Cambridge Isotope Laboratories, Inc. 50 Frontage Rd ANDOVER, MA 01810 USA E-mail Web Site Phone Numbers Emergency Contact Emergency Phone Customer Service Phone Transportation cilsales@isotope.com www.isotope.com Chemtrec 1-800-424-9300 (24 hours) 1-800-322-1174 (8:30-5:30 EST) 1-202-483-7616 (24 hours) 2 HAZARDS IDENTIFICATION OSHA Hazards Carcinogen, Target Organ Effect, Harmful by ingestion. Irritant. Target Organs Central nervous system, Blood, Liver, Cardiovascular system, Kidney. GHS Classification Acute toxicity, Oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2) Carcinogenicity (Category 2) Specific Target Organ Toxicity - Single exposure (Category 2) Hazardous to the aquatic environment, Acute hazard (Category 3) GHS Label Information Signal Word Warning Hazards Identification Health hazard Exclamation mark
Page 2 of 8 Hazard Statement(s) Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing cancer. May cause damage to organs through prolonged or repeated exposure. Harmful to aquatic life. Precautionary Statement(s) Use personal protective equipment as required. IF IN EYES: Rinse with water for several minutes. Remove contact lenses. HMIS Ratings Chronic Health * Physical 1 Flammability 0 Health 2 NFPA Codes Fire 0 Health 2 Reactivity 0 Potential Health Effects Eyes Ingestion Inhalation Skin Causes eye irritation. Harmful if swallowed. May be harmful if inhaled. Causes respiratory tract irritation. Harmful if absorbed through skin. Causes skin irritation. 3 COMPOSITION / INFORMATION ON INGREDIENTS Composition / Information on Ingredients Synonyms Trichloromethane. Methylidyne trichloride. Chemical Formula CDCl3 Molecular Weight 120.38 CAS No. 865-49-6 EC No. 200-663-8 Index No. 602-006-00-4 4 FIRST AID MEASURES First Aid Measures Eyes Flush eye with water for 15 minutes. Get medical attention.
Page 3 of 8 Ingestion Inhalation Skin Additional Information Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get immediate medical attention. Wash with soap and plenty of water. Consult a physician. Move out of dangerous area. Consult a physician and show this safety data sheet. 5 FIRE FIGHTING MEASURE Fire Fighting Measures Extinguishing Media Fire Fighting Equipment Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self contained breathing apparatus for fire fighting if necessary. 6 ACCIDENTAL RELEASE MEASURES Accidental Release Measures Personal Precautions Environmental Precautions Methods and materials for containment and cleanup Use personal protective equipment. Avoid breathing vapors, mist, or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. 7 HANDLING AND STORAGE Precautions for Safe Handling Handling Avoid contact with skin and eyes. Avoid inhalation of vapor or mist. Normal measures for preventive fire protection. Conditions for Safe Storage
Page 4 of 8 Storage Keep container tightly closed in a cool, dry and well-ventilated place. Opened containers must be carefully resealed and kept upright to prevent leakage. 8 EXPOSURE CONTROL / PERSONAL PROTECTION Personal Protecton Eyes - Face Skin Respiratory Protective Clothing Work Hygienic Practices Wear safety glasses with side shields (or goggles) and a face shield. Wear complete suit protecting against chemicals according to concentration and amount of substance. Wear appropriate NIOSH/MSHA approved respirator. Use suitable gloves. Use proper glove removal technique. Wash and dry hands. Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. 9 PHYSICAL AND CHEMICAL PROPERTIES Physical and Chemical Properties (Unlabeled Compound) Form Color Liquid, clear Colourless ph No data available Melting Point -63 C (-81 F) Boiling Point 60.5-61.5 C (140.9-142.7 F) Flashpoint No data available Lower Explosion No data available Limit Upper Explosion No data available Limit Vapor Pressure 213.3 hpa (160.0 mmhg) at 20.0 C (68.0 F) Solubility in Water No data available Partition Coefficient log Pow: 1.97 Auto Ignition No data available Temperature 10 STABILITY AND REACTIVITY Stability and Reactivity
Page 5 of 8 Chemical Stability Conditions to Avoid Hazardous decomposition products Materials to avoid Six months after receipt if stored as stated in "Storage" section. Re-QC after six months. Formed under fire conditions: Carbon oxides, Hydrogen chloride gas. Strong oxidizing agents, Strong bases, Magnesium, Sodium/Sodium oxides, Lithium 11 TOXICOLOGICAL INFORMATION Acute Toxicity LC50 Inhilation Rat LD50 Dermal Rabbit LD50 Oral Rat Serious Damage/Eye Irritation Skin Corrosion/Irritation Inhalation Respiratory or Skin Sensitization Germ Cell Mutagenicity IARC NTP OSHA Reproductive Toxicity 4 h - 47,702 mg/m3 >20,000 mg/kg 695.0 mg/kg No data available No data available No data available 2B- Group 2B: Possibly carcinogenic to humans. Reasonably anticipated to be a human carcinogen. No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Specific Target Organ Toxicity Single Exposure No data available Repeated Exposure No data available Other Information RTECS FS9100000
Page 6 of 8 12 ECOLOGICAL INFORMATION Toxicity Toxicity to Fish LC50 Toxicity to Daphnia and Other Aquatic Invertebrates EC50 Toxicity to Algae and Other Aquatic Plants ErC50 Persistance and Degradability Bioaccumulative Potential Mobility in Soil PBT and vpvb Assessment Other Adverse Effects Leuciscus idus (Golden orfe) - 162.00 mg/l - 48 h Daphnia magna (Water flea) - 79.00 mg/l - 48 h No information available. - 500.00 mg/l - 24 h An environmental hazard cannot be excluded in the event of an unprofessional handling or disposal. Harmful to aquatic life. 13 DISPOSAL CONSIDERATIONS Disposal Considerations Product Disposal Contaminated Packaging Offer surplus and non-recyclable solutions to a licensed disposal company. Contact licensed disposal company to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an after burner and scrubber. Dispose of as unused product. 14 TRANSPORT INFORMATION Transportation Information-DOT/IATA/IMDG UN Number 1888 Prop. Ship. Name Chloroform
Page 7 of 8 Hazard Class 6.1 Packing Group III Reportable Quantity 10 lbs (RQ) DOT US Marine Pollutant No Poison Inhalation No Hazard 15 REGULATORY INFORMATION Regulatory Information Carcinogen, Target Organ Effect, Harmful by ingestion. Irritant. SARA Sara 302 Component Sara 313 Component SARA 311/312 Hazards Acute (Y/N) Chronic (Y/N) Y Y STATE REGULATIONS Massachusetts Right to Know Pennsylvania Right to Know New Jersey Right to Know California Proposition 65 WARNING! This product contains a chemical known by the state of California to cause cancer, birth defects or other reproductive harm. Canada DSL Status EU Hazard All components of this product are on the Canadian DSL list. Irritant Safety Statements
Page 8 of 8 Do not breathe gas/fumes/vapour/spray. Avoid any inhalation, contact with skin and eyes. Wear suitable protective clothing and gloves. Wear suitable protective clothing and gloves. Risk Statements Limited evidence of a carcinogenic effect. 16 OTHER INFORMATION Additional MSDS Information This product is not radioactive. The data given for this product are those of the corresponding unlabeled compound, unless specifically indicated otherwise. Health and safety data for labeled compounds are generally not available, but are assumed to be similar or identical to the corresponding unlabeled compound. Approved On 12/18/12 Version Number 2