Portable Oxygen Concentrator Introduction 1
Oxus Facilities Oxus America, Inc. Auburn Hills, MI USA Incorporated 4/2010 Product Design Manufacturing Regulatory approvals FDA/GMP CE / ISO13485 Responsible for: North America, South America, Europe Oxus, Ltd. Seoul, Korea Incorporated 11/1999 Advanced R&D Product Design Manufacturing Regulatory approvals KFDA CE / ISO 13485 Responsible for Asia Pacific 2
Oxus Products Oxus is a Pressure Swing Adsorption (PSA) gas separation technology company that has been in business for over 13 years Medical Industrial Made in the USA Residential Aquaculture 3
Oxus Portable Oxygen Concentrator Patient friendly Text interface Large / minimum number of buttons Languages user selectable External (easily swapped) battery Superior Performance Extremely sensitive breath detection 850 ml/min output (4+ LPM equivalent cont. flow) Constant bolus up to maximum output 9.7 lbs / 4+ hr battery life Travel friendly design FAA approved Flexible orientation and favorable form factor Reliable Long life, proven compressor Oxus proprietary PSA cycle Membrane dryer 4
User Friendly Interface Display Screen Alarm Indicators On/Off Alarm Silence Check Battery Up/Down 5
Oxus POC Key Features Robust mechanical design: Materials: Aluminum vs. plastic Joints: clamped vs. glued Membrane Dryer for extended sieve bed life Valves: independently tested to 4X life Long life Compressor Proven technology 25,000 hours @ setting 2 Oxus proprietary PSA cycle Minimizes air consumption for improved sieve life On-board oxygen purity sensor for continuous self-diagnosis 6
Oxus POC Specifications Weight 9.7 lbs. Output 850 ml/min, pulse settings 1-5 Breath Detect Sensitivity 0.07 cm H2O Battery Life 4+ hours @ setting 2 / 18 BPM Noise 42 / dba @ 2 pulse 47 / dba @ 5 pulse 7
Oxygen Delivery Effectiveness Pulse Dose Portable Amount of oxygen Per breath, not only max flow spec Purity of oxygen Over the life of the device Accuracy of delivery Sensitivity and accuracy of breath detection Delivered early in inspiration 8
Oxus Pulse Dose Strategy Oxus technology automatically increases the volume of oxygen produced and delivered by holding the bolus size constant as the breath rate increases When the maximum output of the machine is reached, we switch to a fixed minute volume Result: For any settings below the maximum output, as a patient breathes faster, they are receiving more oxygen more oxygen when you need it most Example: Setting 2: Bolus is constant up to 40 breaths / minute 800 Minute Volume vrs Breath Rate Oxus POC Competitor 'I' 25 Bolus Size vs. Breath Rate Oxus POC Competitor 'I' 700 23 21 Minute Volume (ml) 600 500 400 Bolus (ml) 19 17 15 13 300 11 9 200 7 100 20 22 24 26 28 30 32 34 36 38 40 Breath Rate (BPM) 5 20 22 24 26 28 30 32 34 36 38 40 Breath Rate (BPM) Typical COPD Patient Breath Rates 9 Typical COPD Patient Breath Rates
0.16 0.14 0.12 0.1 0.08 0.06 0.04 0.02 0 Breath Detect Sensitivity Inogen Inogen One Airsep Freestyle Airsep Lifestyle Invacare XPO2 10 Respironics Evergo Oxus POC Better Performance Pressure Delta (cm H2O)
Effective Bolus Delivery 11
50 POC Noise Comparison Note: Noise is not just a patient satisfaction issue, but is also a compliance issue! 48 Noise (dba) 46 44 42 40 38 Oxus XPO2 EverGo 12 Note: 3dB is twice the sound power level
Summary Superior clinical efficacy Fixed bolus size with increasing breath rate means less chance of desaturation with increased activity Superior breath detection sensitivity for accurate triggering Improved patient satisfaction (improved compliance) Low noise 4+ hours on each user changeable (external) battery Easy to operate user interface A Professional Duty unit with best in class durability Proprietary OXUS PSA cycle Membrane dryer for improved humidity resistance Robust component design 13