Rsah Ail Iaioal Ayuvdi Mdial Joual ISSN:232 591 CLINICAL EVALUATION OF EFFICACY OF MAHATRIHALADYA GHRITA IN MANAGEMENT OF DRY EYE SYNDROME (SHUSHKAKSHIAKA) Ashwii B N 1, Siva Balaji K 2 1 MS(Ayu), Assisa offso, Dp of Shalakya Taa, Si Jagadguu Gavisiddshwaa Ayuof Ayuvda, vda ollg Koppal, Kaaaka, Idia 2 MS(Ayu), Assisa offso, Dp of Shalakya Taa, Amia shool Kollam, Kala, Idia ABSTRACT Bakgoud & Objivs: Shalakya Taa is o of h bahs of Asaga Ayuvda ad Na oga vigyaa is is sub divisio. Shushkakshipaka (Dy Ey Sydom) is o of h Savagaha Na ogas haaizd by Ghasha (Iiaio), Kuia (hoophobia), Avila Da- ad Rakhaaji shaa (Blud visio), Toda (ikig yp of pai), Daha (Buig ssaio) (Cogsio). All hs sympoms a b olad o h sympoms of Dy Ey Sydom. Ob- Giha jiv of h ps sudy was o valua a obsvaioal sudy of Mahaiphaladya Tapaa i h maagm of Dy Ey Sydom (Shushkakshipaka). Mhods: 5 pais fulfillig h ilusio iia Dy Ey Sydom w adomly sld ad subjd o h ail. Sou of pais: ais w sld adomly fom O..D ad I...D of Shalakya aa, S.D.M. Ayuvdi Collg, Hassa. Cliial sigs ad sympoms w giv wih suia- am. Th bl sos aodig o hi sviy ad assssm was basd o lif af suls havig valu lss ha <.1 w osidd as saisially sigifia i his sudy. Rsuls: Compl missio (% lif) was s i 12%, Makd Impovm i 32%, Moda Impovm i 34%, Mild Impovm was s i 18% pais. Ipaio & Colusio: Mahaiphaladya Giha showd sigifia sul i livig all h sympoms of Shushkakshipaka wih maximumm of 92% ad miimum of 36 %. Ky wods: Ayuvda, Shalakya, Mahaiphaladya Ghia,Tapaa,Shamaa Sha, Shushkak- shipaka, Dy Ey Sydom INTRODUCTION Shushkakshipaka 1 is o amog Savagaa Na Rogas 2 miod by Sushua as wll as Vagbhaa ud Sadhya Vyadhis, ausd by Vaa ad ia Doshas havig sympoms of Ghasha, Toda, Bhda, Upadha, Kihomla, Vishushkaa, Rooksha Daua Vama 3., Amog may y disass, whih hav b idifid by h ai lassis of Ayuvda as wll as mod mdii, h Shushkakshipaka, whihh has b osiys i mod dd as o pa wih Dy mdii, is a majo o. Dy y odiios 4 a a spum of disods wih agig fom mild y sai o Foig Body Ssaio, ai, Buig, wih sigh haig ompliaosidabl dis- ios. ais a hav omfo wih his affliio, whih a i- f wih omal oui fuioig.
Ashwii B N Ms Siva & Balaji K Ms : Cliial Evaluaio Of Effiay Of Mahaiphaladya Ghiai Maagm Of Dy Ey Sydom (Shushkakshipaka) Tapaa 5 is o amog h all impoa Kiyakalpas whih givs ouishm o h ys ad us h Vaa ia disas 6. I is vy muh ssial i h maagm of Shushkakshipaka. Mahaiphaladya Ghia 7 is h impoa fomulaios whih is idiad i Naogas baus of is Chakshushya ad Rasayaa popis. I h ps sudy, i is usd fo Tapaa ad as Shamaa Shaa 8. AIM OF THE STUDY To valua h ff of Mahaiphaladya Giha Tapaa ad Mahaiphaladya Giha as Shamaa Shaa i Shushkakshipaka. Sou of daa: ais w sld fom oupai dpam ad i pai dpam of Shalakya Taa, SDM ollg of Ayuvda ad Hospial, Hassa. 1. paaoy has Day 1 ad 2 (Dipaa): Higvashaka Chua 9 3-5 gm bfo mal wi a day wih lukwam wa Day 3 ad 4 (Shapaa): Go Giha 1 3ml aly moig i mpy somah Day 5(Vihaa): Gadavahasadi aila 11 3 ml aly moig i mpy somah 2. Tam phas: Mahaiphaladya Tapaa ad as Shamaa Sha. Shamaa Sha: Dos : 15 ml wi daily Aupaa : Luk wam wa Mhod of ppaaio of Maha Tiphaladya Ghia: Mahaiphaladya Ghia is ppad as p h lassial ppaaio of Ghia. Ilusio iia: ais of ih sx agd bw 35-7 yas ai psig wih h sympoms sugssiv of Dy Ey Sydom lik iiaio, foig body ssaio(sady), flig of dyss, ihig, oula disomfo,. Ta film bak up im lss ha 1 ss Shim s 1 s posiiv <1 mm. Ros Bgal saiig showig dvializd pihlium of ojuiva ad muus plaqus o h oa Exlusio iia: Sv ass of Dy Ey Sydom wih ompliaios lik pfoad Coal ul, Uviis, Glauoma. Iflammaoy odiios lik Au Cojuiviis Sysmi disass ausig Dy Ey Sydom Follow up: Th follow up was do fo 16 wks fo o vy wo wks. ASSESSMENT OF RESULTS: Eff of h hapis was ompad bfo ad af h am o h basis of Visual Aalogu Sal fo h subjiv paams ad objiv paams. Subjiv aams Flig of dyss Buig ssaio Foig body ssaio ikig pai Rough lids/ muoid dishag/blphiis Suk lids Blud visio Iflammaio / dss Naowig palpbal apu Objiv aams 1. Shim s Ts 1 12. 2. Ta filmbak up Tim 13 OBSERVATIONS 33 www.iamj.i IAMJ: Volum 3; Issu 2; Fbuay- 215
Ashwii B N Ms Siva & Balaji K Ms : Cliial Evaluaio Of Effiay Of Mahaiphaladya Ghiai Maagm Of Dy Ey Sydom (Shushkakshipaka) Sviy of h ovall Sympoms of Dy Ey 8 6 4 2 98 96 88 37 21 35 1 2 RESULTS Impovm i Flig of Dyss 8 6 4 2 8 6 4 2 68 72 8 84 55 34 14h Day 28h Day 42d Day 56h Day 7h Day 84h Day Impovm i Buig ssaio 85 92 67 53 37 14h Day 28h Day 42d Day 56h Day 7h Day 84h Day Impovm i Foig Body ssaio 8 6 4 2 38 14h Day 63 63 76 83 81 28h Day 42d Day 56h Day 7h Day 84h Day 331 www.iamj.i IAMJ: Volum 3; Issu 2; Fbuay- 215
Ashwii B N Ms Siva & Balaji K Ms : Cliial Evaluaio Of Effiay Of Mahaiphaladya Ghiai Maagm Of Dy Ey Sydom (Shushkakshipaka) Impovm i ikig ai 8 6 4 2 41 14h Day 74 81 8 6 49 28h Day 42d Day 56h Day 7h Day 84h Day 8 6 4 2 Impovm i Rough lids/ Muoid Dishag 68 14h Day 92 76 92 97 28h Day 42h Day 56h Day 7h Day 84h Day 8 6 4 2 37 14h Day Impovm i Suk Lids 89 84 63 28h Day 42d Day 56h Day 7h Day 84h Day 5 Impovm i Blud Visio 84 97.36 63 14h Day 28h Day 42d Day 56h Day 7h Day 84h Day 332 www.iamj.i IAMJ: Volum 3; Issu 2; Fbuay- 215
Ashwii B N Ms Siva & Balaji K Ms : Cliial Evaluaio Of Effiay Of Mahaiphaladya Ghiai Maagm Of Dy Ey Sydom (Shushkakshipaka) 5 Impovm iiflammaio 8 8 4 14h Day 28h Day 42d Day 56h Day 7h day 84h day Rlif i Naowig of alpbal Apu 5 14h Day 28h Day 42d Day 56h Day 7h Day 84h Day Impovm i Ta Film Bak Up Tim- LE 8 6 4 2 14 14h Day 17 22 3 32 36 28h Day 42h Day 56h Day 7h Day 84h Day Impovm i Shim's Ts-LE 8 6 4 2 19 14h Day 41 28 35 38 41 28h Day 42h Day 56h Day 7h Day 84h Day 333 www.iamj.i IAMJ: Volum 3; Issu 2; Fbuay- 215
Ashwii B N Ms Siva & Balaji K Ms : Cliial Evaluaio Of Effiay Of Mahaiphaladya Ghiai Maagm Of Dy Ey Sydom (Shushkakshipaka) Ovall Eff of Mahaiphaladya Giha o Dy Ey Sydom 75 5 25 12 ompl missio 32 34 18 4 makd moda mild uhagd DISCUSSION Mahaiphaladya Giha as big h bs immuomodulao, i ofs ai i- y sy- flammaoy aiviy ad i dy dom hby pvs T lls fom - - 6) lasig yokis (pimaily iluki ha ii h iflammaoy ompo of dy y. Compoay a subsius simu- ha la h ll sufa glyoopois maiai oula hydaio ad muoadhsiv popy du o lipid o i i. Th dg of oa im wih h oula sufa of a subsius gally ags fom 1.5mL pas (asal sods, a sadad of masum fo visosiy) o 15 ml pas, wih a avag of 5. ml pas whih a availabl i maks. Compad o hs aifiial a podus, as Tiphala Giha is ih i lipid o whih fls muoadhsiv popis ad hfo h dg of oa im wih h oula sufa is ga. H, h ff of Tapaa is b as i has go oa im mo ha 2 mius. Tapaa simulas h osuio of h a film ad h Shohahaa popy of Mahaiphaladya Gia dus h iflam- maoy hags du o Shushkakshipaka. CONCLUSION Thus, Mahaiphaladya Gia o- h a ols h iflammaio, osus film, hby poduig opimal hydaio i h y offig a pomis of log lasig lif o pais wih moda o sv dy y sympoms. REFERENCES 1. Sikahamuhy KR(d). Susuha Sam- aslaio hia of Susuha wih Eglish ad ommmay.22 pid. Vaa- 137 asi: Chaukhambaoialia:22.p. 2. Sikahamuhy KR(d). Susuha Sam- aslaio hia of Susuha wih Eglish ad ommmay.22 pid. Vaa- 137 asi: Chaukhambaoialia:22.p. 3. Sikahamuhy KR(d). Susuha Sam- aslaio hia of Susuha wih Eglish ad ommmay.22 pid. Vaa- 137 asi: Chaukhambaoialia:22.p. 4. Khuaa AK, Choudhay R, Ahluwalia BK, Gupa S. Hospial pidmiology of dy y. Idia J Ophhalmol 1991;39:55-8 5. Sushua Samhia, Uaa Taa of Mawih hashi Sushua, Edid Ayuvdi Tawa Sadipika. By Kavia- ja Ambikadua Shahi a II. Vaa- 6. Sikahamuhy KR(d). Susuha Sam- asi: Chaukhambaoialia:24.p.149 hia of Susuha wih Eglish aslaio 334 www.iamj.i IAMJ: Volum 3; Issu 2; Fbuay- 215
Ashwii B N Ms Siva & Balaji K Ms : Cliial Evaluaio Of Effiay Of Mahaiphaladya Ghiai Maagm Of Dy Ey Sydom (Shushkakshipaka) ad ommmay.22 pid. Vaaasi: Chaukhambaoialia:22.p. 149 7. Th Ayuvdi Fomulay of Idia.dpam of idia sysm of mdii & homoopahy pa I.Dlhi : Th ooll of publiaio ivil lis :p.75 8. Th Ayuvdi Fomulay of Idia.dpam of idia sysm of mdii & homoopahy pa I.Dlhi : Th ooll of publiaio ivil lis :p.95 9. Th Ayuvdi Fomulay of Idia.dpam of idia sysm of mdii & homoopahy pa I.Dlhi : Th ooll of publiaio ivil lis :p.95 1. Shama R K, Dash B (d). Chaaka Samhia of Agivsa wih Ayuvda Dipika of Cakapaidaa.27 pid. Vaaasi: Chaukhambaoialia:27.p.16 11. Dy y ad Oula sufa disods dio Sush k ady, pub by jayp bohs mdial publishs() Ld. 12. Dy y ad Oula sufa disods dio Sush k ady, pub by jayp bohs mdial publishs() Ld. CORRESONDING AUTHOR D. Ashwii B N MS(Ayu), Assisa ofsso, Dp of Shalakya Taa, Koppal, Kaaaka, Idia Email: dashwiiblludi@gmail.om Sou of suppo: Nil Cofli of is: No Dlad 335 www.iamj.i IAMJ: Volum 3; Issu 2; Fbuay- 215