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SAFETY DATA SHEET (SDS): According to the OSHA Hazard Communication Standard 29 CFR 1910.1200 Issuing Date: 2014-01-31 Revision Date: 2014-01-31 Version: 1 SECTION 1. Identification Product identifier Product No. Product name UN number Description Other means of identification 12369 Nitrocellulose Sandwiches UN3270 Nitrocellulose Sandwiches from Cell Signaling Technology are pre-packaged sandwiches consisting of a precut nitrocellulose membrane and 2 sheets of 0.34 mm thick blotting paper for protein detection during western blotting. 12369M, 12369P, 12369P2, 12369S Recommended use of the chemical and restrictions on use Identified uses Uses advised against Manufacturer, importer, supplier This product is intended for research purposes only. This product is not intended for use in diagnostic procedures or therapeutics. This product is not intended for use in humans or animals. Manufacturer address Cell Signaling Technology, Inc. 3 Trask Lane Danvers, MA 01923 TEL: +1 978 867 2300 FAX: +1 978 867 2400 Website www.cellsignal.com Email address support@cellsignal.com Company phone number 978-867-2300 Emergency telephone number In case of emergency call CHEMTREC 1-800-424-9300 Classification SECTION 2. Hazard(s) identification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Flammable solids Category 1 GHS Label elements, including precautionary statements Signal Word Page 1 / 8

Danger Hazard statement(s) Flammable solid. Precautionary Statement(s) Keepawayfrom heat/sparks/openflames/hotsurfaces. Nosmoking.Ground/Bondcontainerandreceivingequipment.Wear protective gloves/protective clothing/eye protection/face protection. Supplementary Hazard Information Hazards not otherwise classified (HNOC) None SECTION 3. Composition/information on ingredients Chemical nature Common name Synonyms Mixture of nitric esters of cellulose. Cellulose nitrate (nitrocellulose) containing a maximum of 12.6% nitrogen cellulose nitrate, nitrocellulose, nitrocellulose membrane filter. Chemical Name nitrocellulose, containing a maximum of 12,6 % nitrogen CAS No. Weight % 9004-70-0 100 SECTION 4. First-aid measures Eye contact Skin contact Inhalation Ingestion Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Consult a physician. Wash skin with soap and water. Move to fresh air. Clean mouth with water and afterwards drink plenty of water. Most important symptoms and effects, both acute and delayed No information or data specific to the product on this toxicological (health) effect is available. Indication of any immediate medical attention and special treatment needed Notes to physician Treat symptomatically. Advice for emergency responders General advice Protection of First-aiders For further assistance, contact your local Poison Control Center. Ensure that medical personnel are aware of the material(s) involved, and take precautions to protect themselves. SECTION 5. Fire-fighting measures Extinguishing media Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Unsuitable Extinguishing Media None. Specific hazards arising from the chemical Extremely flammable. Will be easily ignited by heat, sparks or flames. Page 2 / 8

Explosion Data Sensitivity to Mechanical Impact Not impact sensitive. Sensitivity to Static Discharge Yes. Protective Equipment and Precautions for Firefighters In the event of fire and/or explosion do not breathe fumes. Use self-contained pressure-demand breathing apparatus if needed to prevent exposure to smoke or airborne toxins. SECTION 6. Accidental release measures Personal precautions, protective equipment and emergency procedures For non-emergency personnel Other information For emergency responders ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). During unexpected circumstances and elevated temperatures such as a fire, evacuate personnel to safe areas and use personal protective equipment to prevent exposure to volatiles. Keep substance wet using water spray. Use personal protective equipment as required. Environmental precautions Should not be released into the environment. See Section 12 for additional information. Methods and material for containment and cleaning up Methods for containment Methods for cleaning up Prevent further leakage or spillage if safe to do so. Use personal protective equipment. Flush area with flooding quantities of water. Take up mechanically and collect in suitable container for disposal. Clean contaminated surface thoroughly. SECTION 7. Handling and storage Precautions for safe handling Handle in accordance with good industrial hygiene and safety practice. Take precautionary measures against static discharges. Remove all sources of ignition. Use according to package label instructions. Conditions for safe storage, including any incompatibilities Technical measures/storage conditions Packaging material Incompatible products Keep container tightly closed in a dry and well-ventilated place. Keep away from open flames, hot surfaces and sources of ignition. For safety reasons in case of fire, cans should be stored separately in closed containments.. Strong oxidizing agents, strong acids, and strong bases. SECTION 8. Exposure controls/personal protection Control parameters This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. Appropriate engineering controls Page 3 / 8

12369 - Nitrocellulose Sandwiches Revision Date: 2014-01-31 Process enclosure and/or ventilation systems. Individual protection measures, such as personal protective equipment Eye/face protection Skin and body protection Respiratory protection Hygiene measures Safety glasses with side-shields. Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. None required under normal usage. If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Respiratory protection must be provided in accordance with current local regulations. Handle in accordance with good industrial hygiene and safety practice. SECTION 9. Physical and chemical properties Information on basic physical and chemical properties Physical state Solid Appearance 7 X 8.5 cm membrane Odor Odorless Color White to off-white Odor Threshold ph Melting point/freezing point Initial boiling point and boiling range Flash point Evaporation rate Flammability (solid, gas) Upper flammability limit Lower flammability limit Vapor pressure Vapor density Relative density Solubility Solubility in other solvents Partition coefficient: n-octanol/water Autoignition temperature >160 C Decomposition temperature Explosive properties Oxidizing properties VOC content Viscosity Density SECTION 10. Stability and reactivity Reactivity Reacts with incompatible materials causing a fire and explosioin hazard. Chemical stability Stable under recommended storage conditions. Decomposes violently under high temperature. Possibility of hazardous reactions Hazardous reactions Hazardous polymerization Exothermic reaction possible with strong oxidizers. None under normal processing. Page 4 / 8

Conditions to Avoid Heat, flames and sparks. Exposure to UV-rays. Storage near to reactive materials. Incompatible Materials Strong oxidizing agents, strong acids, and strong bases. Hazardous Decomposition Products Hazardous decomposition products formed under fire conditions: Nitrogen oxides (NOx), Carbon oxides, Aldehydes. Information on likely routes of exposure SECTION 11. Toxicological information Inhalation Eye contact Skin contact Ingestion There is no data available for this product. There is no data available for this product. There is no data available for this product. There is no data available for this product. Information on toxicological effects This material should only be handled by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals. It should be borne in mind that the toxocological and physiological properties of this compound is not well defined. Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation nitrocellulose, containing a > 5 g/kg ( Rat ) - - maximum of 12,6 % nitrogen 9004-70-0 Delayed and immediate effects as well as chronic effects from short and long-term exposure Symptoms. Corrosivity. Sensitization. Mutagenic effects. Carcinogenicity No component of this product present at levels greater than or equal to 0.1% is identifiable as probable, possible or confirmed carcinogen by IARC, ACGIH, NTP, or OSHA. Reproductive toxicity. Developmental Toxicity. Teratogenicity. STOT - single exposure. STOT - repeated exposure. Neurological effects. Aspiration Hazard. Endocrine Disruptor Information. Ecotoxicity SECTION 12. Ecological information 100% of the mixture consists of components(s) of unknown hazards to the aquatic environment Page 5 / 8

Persistence and degradability. Bioaccumulation. Mobility Other adverse effects. SECTION 13. Disposal considerations Waste Disposal Methods Dispose of in accordance with all applicable national environmental laws and regulations. Disposal considerations Do not empty into drains; dispose of this material and its container in a safe way. SECTOIN 14. Transport information DOT UN number Transport hazard class(es) Packing Group Description Emergency Response Guide Number UN3270 4.1 II UN3270, Nitrocellulose membrane filters, 4.1, II 133 IATA UN number UN3270 Transport hazard class(es) 4.1 Packing Group II ERG Code 3L Description UN3270, Nitrocellulose membrane filters, 4.1, II IMDG/IMO UN number UN3270 Transport hazard class(es) 4.1 Packing group II EmS No. F-A, S-I Description UN3270, Nitrocellulose membrane filters, 4.1, II SECTION 15. Regulatory information All of the components in the product are on the following Inventory lists: TSCA Complies Page 6 / 8

DSL Complies NDSL Complies SARA 313 Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372. SARA 311/312 Hazard Categories Acute Health Hazard Chronic Health Hazard Fire Hazard Sudden Release of Pressure Hazard Reactive Hazard No No Yes No No Clean Water Act This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42). CERCLA This material, as supplied, does not contain any substances regulated as hazardous substances under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments and Reauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state level pertaining to releases of this material. California Proposition 65 This product does not contain any Proposition 65 chemicals. U.S. State Right-to-Know Regulations Chemical Name New Jersey Massachusetts Pennsylvania nitrocellulose, containing a maximum of 12,6 % nitrogen 9004-70-0 Listed Listed Listed U.S. EPA Label Information This product does not contain any substances regulated as pesticides. Issuing Date: 2014-01-31 Revision Date: 2014-01-31 Disclaimer SECTION 16. Other information The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. Page 7 / 8

End of Safety Data Sheet Page 8 / 8