SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING

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1 SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING PRODUCT NAME: PRODUCT PART NUMBER: POP-6 PERFORMANCE OPTIMIZED POLYMER SUPPLIER: APPLIED BIOSYSTEMS 7 KINGSLAND GRANGE, WOOLSTON WARRINGTON, CHESHIRE, WA1 4SR, UNITED KINGDOM IN CASE OF EMERGENCY, CALL CHEMTREC: INTERNATIONAL, REVERSE CHARGES PRODUCT USE DESCRIPTION: FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. 2. COMPOSITION/INFORMATION ON INGREDIENTS EC-No. Component(s) CAS-No. (EINECS-No.) Weight % Classification Trade Secret Proprietary 1-10 % Xn R22, R36/37/38, R63 Harmful UREA % Xi R36/38 Irritant 3. HAZARDS IDENTIFICATION European Union Classification: Xi Irritant Risk phrases R36/38 Irritating to eyes and skin. Safety phrases S24 S26 S37 S60 Avoid contact with skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable gloves. This material and its container must be disposed of as hazardous waste. Page 1 of 6 REVISION DATE:

2 4. FIRST AID MEASURES Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention immediately. Inhalation: Skin contact: Ingestion: Move to fresh air. Give oxygen or artificial respiration if not breathing Get medical attention immediately. Wash off immediately with plenty of water. Remove and wash contaminated clothing before re-use. Get medical attention immediately. If swallowed, seek medical advice immediately and show this container or label. Never give anything by mouth to an unconscious person. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Water spray Carbon dioxide (CO2) Foam Dry chemical Special protective equipment for fire-fighters Wear self contained breathing apparatus for fire fighting if necessary. Use personal protective equipment. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Avoid Inhalation. Environmental precautions Should not be released into the environment. Methods for cleaning up Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local/national regulations (see section 13). 7. HANDLING AND STORAGE Precautions for safe handling Use only in area provided with appropriate exhaust ventilation. Wear personal protective equipment. Page 2 of 6 REVISION DATE:

3 Storage conditions Protect against physical damage. Isolate from incompatible substances. Store in original container. See product label for specific storage requirements. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Exposure limit(s) We are not aware of any national exposure limit. Eye protection Hand protection Respiratory protection Skin protection Engineering measures Use appropriate safety glasses with side-shields or chemical safety goggles. Ensure that eyewash stations and safety showers are close to the workstation location. Impervious gloves should be worn to prevent skin contact and absorption. Contact glove provider for specific recommendations. Avoid breathing vapor. For unknown concentrations or Immediately Dangerous to Life or Health (IDLH), use a full-facepiece positive pressure air supplied respirator. Wear suitable protective clothing. Use adequate local exhaust ventilation or other engineering controls to minimize exposure to vapor. 9. PHYSICAL AND CHEMICAL PROPERTIES Physical state Colour Odour Odour threshold ph Boiling point Melting point Vapour pressure Water solubility Flash point Explosion limits Density Percent volatile Volatile organic compounds (VOC) content liquid 10. STABILITY AND REACTIVITY Conditions to avoid Keep away from open flames, hot surfaces and sources of ignition. 11. TOXICOLOGICAL INFORMATION Component : Proprietary Acute oral toxicity Oral LD50 rat 8 mg/kg Page 3 of 6 REVISION DATE:

4 Component : UREA Acute oral toxicity Oral LD50 rat 8,471 mg/kg Further information The toxicological properties of this product have not been thoroughly investigated. Use appropriate precautions. 12. ECOLOGICAL INFORMATION We have no quantitative data concerning the ecological effects of this product. An environmental hazard cannot be excluded in the event of unprofessional handling or disposal. Component: Proprietary Ecotoxicity effects Toxicity to fish Toxicity to algae Static LC50 Brachydanio rerio (zebra fish) 96 h 4,600-10,000 mg/l EC50 Scenedesmus subspicatus 72 h 250 mg/l EC50 Scenedesmus subspicatus 96 h 84 mg/l Toxicity to bacteria EC50 Photobacterium phosphoreum 30 min 759 mg/l EC50 Pseudomonas putida 17 h > 10,000 mg/l Toxicity to daphnia EC50 Daphnia magna (Water flea) 96 h 3.4 mg/l UREA Ecotoxicity effects Toxicity to fish Toxicity to bacteria Toxicity to daphnia LC50 Leuciscus idus (Golden orfe) 96 h > 3,810 mg/l EC50 Photobacterium phosphoreum 5 min 23,914 mg/l EC50 Daphnia magna Straus 24 h > 10,000 mg/l Page 4 of 6 REVISION DATE:

5 13. DISPOSAL CONSIDERATIONS Environmental precautions Disposal methods General advice Should not be released into the environment. Dispose of in accordance with local regulations. DISPOSAL CONSIDERATIONS The product has to be disposed of as laboratory chemical in accordance with local regulations. 14. TRANSPORT INFORMATION IATA-DGR AIR TRANSPORT: IATA CARGO AIR TRANSPORT: IATA PASSENGER IMDG ADR 15. REGULATORY INFORMATION Labelling Hazard symbol(s) and indication(s) of danger for dangerous substances and preparations Xi: Irritant R-phrase(s) R36/38 Irritating to eyes and skin. S-phrase(s) S24 S26 S37 S60 Avoid contact with skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable gloves. This material and its container must be disposed of as hazardous waste. Page 5 of 6 REVISION DATE:

6 National Inventory Status - European Union EUROPEAN INVENTORY OF EXISTING CHEMICAL SUBSTANCES (EINECS) All components of this substance are listed on or are exempt from the inventory. EUROPEAN LIST OF NOTIFIED CHEMICAL SUBSTANCES (ELINCS) All components of this substance are listed on or are exempt from the inventory. EUROPEAN NO-LONGER POLYMERS LIST (NLP) All components of this substance are listed on or are exempt from the inventory. 16. OTHER INFORMATION Disclaimer: This MSDS has been prepared using information from sources considered technically reliable. It should not be relied upon as a product specification. The company makes no warranty of any kind, expressed or implied, concerning the safe use of this material in your process or in combination with other chemical substances. Every user of the product is responsible for evaluating its own processes and conditions of use and selecting appropriate protective measures for employee exposure. Text of R-phrases mentioned in Section 2 R22 Harmful if swallowed. R36/37/38 Irritating to eyes, respiratory system and skin. R36/38 Irritating to eyes and skin. R63 Possible risk of harm to the unborn child. Legend ACGIH OSHA PEL STEL TLV TWA American Conference of Governmental Industrial Hygenists Occupational Safety and Health Act Permissable exposure limit Short term exposure limit Threshold limit value Time weighted average Document no Print Date 5/10/ :40:00 PM Page 6 of 6 REVISION DATE:

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