Kit components Trans -Blot Turbo RTA Transfer PVDF Kit

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1 06/16/2015 Product code Kit components Description Trans -Blot Turbo RTA Transfer PVDF Kit Components: Trans-Blot Turbo 5x Transfer Buffer Trans-Blot Turbo Transfer Stacks Trans-Blot Turbo PVDF Membrane

2 Page 1/7 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier Trade name: Trans-Blot Turbo 5x Transfer Buffer Article number: , Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the mixture Laboratory chemicals 1.3 Details of the supplier of the safety data sheet Manufacturer/Supplier: Bio-Rad Laboratories S.r.l. Via Cellini, 18A Segrate-Milano Italy phone: fax: lsg_info_it@bio-rad.com / diagnostics_italy@bio-rad.com Information department: Technical services, customer support. lsg_info_it@bio-rad.com / diagnostics_italy@bio-rad.com 1.4 Emergency telephone number: active during office hours for technical information * SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Eye Irrit. 2 H319 Causes serious eye irritation. Resp. Sens. 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. 2.2 Label elements Labelling according to Regulation (EC) No 1272/2008 The product is classified and labelled according to the CLP regulation. Hazard pictograms GHS08 Signal word Danger Hazard-determining components of labelling: Proprietary Reagent S Hazard statements H319 Causes serious eye irritation. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. Precautionary statements P285 In case of inadequate ventilation wear respiratory protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. (Contd. on page 2)

3 Page 2/7 Trade name: Trans-Blot Turbo 5x Transfer Buffer P501 Dispose of contents/container in accordance with local/regional/national/international regulations. 2.3 Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. (Contd. of page 1) * SECTION 3: Composition/information on ingredients 3.2 Chemical characterisation: Mixtures Description: Mixture of the substances listed below with nonhazardous additions. Dangerous components: Proprietary Reagent K Eye Irrit. 2, H319 Proprietary Amino Acid I Eye Irrit. 2, H319 Proprietary Reagent S Acute Tox. 3, H311 Resp. Sens. 1, H334 Acute Tox. 4, H302; Acute Tox. 4, H332; Skin Irrit. 2, H315; Eye Irrit. 2, H319; STOT SE 3, H335 Additional information For the wording of the listed risk phrases refer to section % 5-10% 1,0-2,5% * SECTION 4: First aid measures 4.1 Description of first aid measures After inhalation Supply fresh air; consult doctor in case of complaints. After eye contact Rinse opened eye for several minutes under running water. After swallowing Induce vomiting and call for medical help. 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available. 4.3 Indication of any immediate medical attention and special treatment needed No further relevant information available. * SECTION 5: Firefighting measures 5.1 Extinguishing media Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. 5.2 Special hazards arising from the substance or mixture No further relevant information available. 5.3 Advice for firefighters Protective equipment: No special measures required. * SECTION 6: Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures Wear protective clothing. 6.2 Environmental precautions: Dilute with plenty of water. Do not allow to enter sewers/ surface or ground water. (Contd. on page 3)

4 Page 3/7 Trade name: Trans-Blot Turbo 5x Transfer Buffer 6.3 Methods and material for containment and cleaning up: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). 6.4 Reference to other sections See Section 7 for information on safe handling See Section 8 for information on personal protection equipment. See Section 13 for disposal information. (Contd. of page 2) * SECTION 7: Handling and storage 7.1 Precautions for safe handling No special precautions are necessary if used correctly. Information about protection against explosions and fires: No special measures required. 7.2 Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: According to product specification Information about storage in one common storage facility: Not required. Further information about storage conditions: None. 7.3 Specific end use(s) No further relevant information available. * SECTION 8: Exposure controls/personal protection Additional information about design of technical systems: No further data; see item Control parameters Components with limit values that require monitoring at the workplace: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace. Additional information: The lists that were valid during the creation were used as basis. 8.2 Exposure controls Personal protective equipment General protective and hygienic measures Wash hands before breaks and at the end of work. Breathing equipment: Not required. Protection of hands: Protective gloves. Material of gloves Synthetic gloves Penetration time of glove material The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Safety glasses SECTION 9: Physical and chemical properties 9.1 Information on basic physical and chemical properties General Information Appearance: Form: Fluid Colour: Colourless Odour: Odourless Odour threshold: (Contd. on page 4)

5 Page 4/7 Trade name: Trans-Blot Turbo 5x Transfer Buffer ph-value: Change in condition Melting point/melting range: Boiling point/boiling range: undetermined undetermined Flash point: Not applicable Flammability (solid, gaseous) Not applicable. Ignition temperature: Decomposition temperature: Self igniting: Product is not selfigniting. Danger of explosion: Product does not present an explosion hazard. Explosion limits: Lower: Upper: Vapour pressure at 20 C: 23 hpa Density at 20 C: 0,96246 g/cm³ Relative density Vapour density Evaporation rate Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: kinematic: Solvent content: Organic solvents: 0,0 % Water: 74,8 % Solids content: 25,2 % 9.2 Other information No further relevant information available. (Contd. of page 3) SECTION 10: Stability and reactivity 10.1 Reactivity 10.2 Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications Possibility of hazardous reactions No dangerous reactions known 10.4 Conditions to avoid No further relevant information available Incompatible materials: No further relevant information available Hazardous decomposition products: No dangerous decomposition products known (Contd. on page 5)

6 Page 5/7 Trade name: Trans-Blot Turbo 5x Transfer Buffer (Contd. of page 4) * SECTION 11: Toxicological information 11.1 Information on toxicological effects Acute toxicity: LD/LC50 values that are relevant for classification: Proprietary Reagent K Oral LD mg/kg (rat) Proprietary Reagent EB II Oral LD mg/kg (rat) Dermal LD mg/kg (rat) Proprietary Reagent S Oral LD mg/kg (rat) Dermal LD mg/kg (rab) Primary irritant effect: on the eye: Irritating effect. Sensitisation: No sensitising effects known. SECTION 12: Ecological information 12.1 Toxicity Aquatic toxicity: No further relevant information available Persistence and degradability No further relevant information available Bioaccumulative potential No further relevant information available Mobility in soil No further relevant information available. Additional ecological information: General notes: Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable Other adverse effects No further relevant information available. SECTION 13: Disposal considerations 13.1 Waste treatment methods Recommendation Must not be disposed of together with household garbage. Do not allow product to reach sewage system. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. Recommended cleansing agent: Water, if necessary with cleansing agents. (Contd. on page 6)

7 Page 6/7 Trade name: Trans-Blot Turbo 5x Transfer Buffer (Contd. of page 5) SECTION 14: Transport information 14.1 UN-Number ADR, ADN, IMDG, IATA Void 14.2 UN proper shipping name ADR, ADN, IMDG, IATA Void 14.3 Transport hazard class(es) ADR, ADN, IMDG, IATA Class Void 14.4 Packing group ADR, IMDG, IATA Void 14.5 Environmental hazards: Marine pollutant: No 14.6 Special precautions for user Not applicable Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code UN "Model Regulation": - Not applicable. * SECTION 15: Regulatory information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture National regulations Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water Chemical safety assessment: A Chemical Safety Assessment has not been carried out. SECTION 16: Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Relevant phrases H302 Harmful if swallowed. H311 Toxic in contact with skin. H315 Causes skin irritation. H319 Causes serious eye irritation. H332 Harmful if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. Department issuing SDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) (Contd. on page 7)

8 Page 7/7 Trade name: Trans-Blot Turbo 5x Transfer Buffer (Contd. of page 6) Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association GHS: Globally Harmonised System of Classification and Labelling of Chemicals EINECS: European Inventory of Existing Commercial Chemical Substances ELINCS: European List of Notified Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent Acute Tox. 4: Acute toxicity, Hazard Category 4 Acute Tox. 3: Acute toxicity, Hazard Category 3 Skin Irrit. 2: Skin corrosion/irritation, Hazard Category 2 Eye Irrit. 2: Serious eye damage/eye irritation, Hazard Category 2 Resp. Sens. 1: Sensitisation - Respirat., Hazard Category 1 STOT SE 3: Specific target organ toxicity - Single exposure, Hazard Category 3 * Data compared to the previous version altered.

9 Page 1/6 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier Trade name: Trans-Blot Turbo Transfer Stacks Article number: , , , Index number: Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the mixture Laboratory chemicals 1.3 Details of the supplier of the safety data sheet Manufacturer/Supplier: Bio-Rad Laboratories S.r.l. Via Cellini, 18A Segrate-Milano Italy phone: fax: lsg_info_it@bio-rad.com / diagnostics_italy@bio-rad.com Information department: Technical services, customer support. lsg_info_it@bio-rad.com / diagnostics_italy@bio-rad.com 1.4 Emergency telephone number: active during office hours for technical information * SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 The substance is not classified according to the CLP regulation. Classification according to Directive 67/548/EEC or Directive 1999/45/EC not applicable Information concerning particular hazards for human and environment: not applicable 2.2 Label elements Labelling according to Regulation (EC) No 1272/2008 Void Hazard pictograms Void Signal word Void Hazard statements Void Precautionary statements P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P280 Wear protective clothing / eye protection. P402 Store in a dry place. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. 2.3 Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. * SECTION 3: Composition/information on ingredients 3.1 Chemical characterisation: Substances CAS No. Description: Covering Membranes (Contd. on page 2)

10 Page 2/6 Trade name: Trans-Blot Turbo Transfer Stacks Identification number(s): Index number: Additonal information: For the wording of the listed risk phrases refer to section 16. (Contd. of page 1) SECTION 4: First aid measures 4.1 Description of first aid measures After inhalation Supply fresh air; consult doctor in case of complaints. After skin contact Generally the product does not irritate the skin. After eye contact Rinse opened eye for several minutes under running water. After swallowing Induce vomiting and call for medical help. 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available. 4.3 Indication of any immediate medical attention and special treatment needed No further relevant information available. * SECTION 5: Firefighting measures 5.1 Extinguishing media Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. 5.2 Special hazards arising from the substance or mixture No further relevant information available. 5.3 Advice for firefighters Protective equipment: No special measures required. * SECTION 6: Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures Wear protective clothing. 6.2 Environmental precautions: No special measures required. 6.3 Methods and material for containment and cleaning up: Pick up mechanically. 6.4 Reference to other sections No dangerous substances are released. See Section 7 for information on safe handling See Section 8 for information on personal protection equipment. See Section 13 for disposal information. * SECTION 7: Handling and storage 7.1 Precautions for safe handling No special measures required. Information about protection against explosions and fires: No special measures required. 7.2 Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: According to product specification Information about storage in one common storage facility: Not required. Further information about storage conditions: None. (Contd. on page 3)

11 Page 3/6 Trade name: Trans-Blot Turbo Transfer Stacks 7.3 Specific end use(s) No further relevant information available. (Contd. of page 2) SECTION 8: Exposure controls/personal protection Additional information about design of technical systems: No further data; see item Control parameters Components with limit values that require monitoring at the workplace: Not required. Additional information: The lists that were valid during the creation were used as basis. 8.2 Exposure controls Personal protective equipment General protective and hygienic measures The usual precautionary measures should be adhered to when handling chemicals. Protection of hands: Protective gloves. Material of gloves Synthetic gloves Penetration time of glove material The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Safety glasses SECTION 9: Physical and chemical properties 9.1 Information on basic physical and chemical properties General Information Appearance: Form: Colour: Odour: Odourless Odour threshold: ph-value: Not applicable. Change in condition Melting point/melting range: Boiling point/boiling range: undetermined undetermined Flash point: Not applicable Flammability (solid, gaseous) Product is not flammable. Ignition temperature: Decomposition temperature: Self igniting: Danger of explosion: Product does not present an explosion hazard. Explosion limits: Lower: Upper: Vapour pressure: Not applicable. Density at 20 C: 1,65 g/cm³ (Contd. on page 4)

12 Page 4/6 Trade name: Trans-Blot Turbo Transfer Stacks Relative density Vapour density Not applicable. Evaporation rate Not applicable. Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: Not applicable. kinematic: Not applicable. Organic solvents: 0,0 % Solids content: 100,0 % 9.2 Other information No further relevant information available. (Contd. of page 3) SECTION 10: Stability and reactivity 10.1 Reactivity 10.2 Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications Possibility of hazardous reactions No dangerous reactions known 10.4 Conditions to avoid No further relevant information available Incompatible materials: No further relevant information available Hazardous decomposition products: No dangerous decomposition products known * SECTION 11: Toxicological information 11.1 Information on toxicological effects Acute toxicity: Primary irritant effect: on the skin: No irritant effect. on the eye: No irritating effect. Sensitisation: No sensitising effects known. Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. The substance is not subject to classification according to the latest version of the EU lists. SECTION 12: Ecological information 12.1 Toxicity Aquatic toxicity: No further relevant information available Persistence and degradability No further relevant information available Bioaccumulative potential No further relevant information available Mobility in soil No further relevant information available. Additional ecological information: General notes: Generally not hazardous for water. (Contd. on page 5)

13 Page 5/6 Trade name: Trans-Blot Turbo Transfer Stacks 12.5 Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable Other adverse effects No further relevant information available. (Contd. of page 4) SECTION 13: Disposal considerations 13.1 Waste treatment methods Recommendation Hand over to hazardous waste disposers. Must not be disposed of together with household garbage. Do not allow product to reach sewage system. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. SECTION 14: Transport information 14.1 UN-Number ADR, ADN, IMDG, IATA Void 14.2 UN proper shipping name ADR, ADN, IMDG, IATA Void 14.3 Transport hazard class(es) ADR, ADN, IMDG, IATA Class Void 14.4 Packing group ADR, IMDG, IATA Void 14.5 Environmental hazards: Marine pollutant: No 14.6 Special precautions for user Not applicable Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code UN "Model Regulation": - Not applicable. * SECTION 15: Regulatory information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture National regulations Water hazard class: Generally not hazardous for water Chemical safety assessment: A Chemical Safety Assessment has not been carried out. (Contd. on page 6)

14 Page 6/6 Trade name: Trans-Blot Turbo Transfer Stacks (Contd. of page 5) SECTION 16: Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing SDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association GHS: Globally Harmonised System of Classification and Labelling of Chemicals CAS: Chemical Abstracts Service (division of the American Chemical Society) * Data compared to the previous version altered.

15 Page 1/6 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier Trade name: Trans-Blot Turbo PVDF Membrane Article number: , , , , , CAS Number: Index number: Relevant identified uses of the substance or mixture and uses advised against No further relevant information available. Application of the substance / the mixture Laboratory chemicals 1.3 Details of the supplier of the safety data sheet Manufacturer/Supplier: Bio-Rad Laboratories S.r.l. Via Cellini, 18A Segrate-Milano Italy phone: fax: lsg_info_it@bio-rad.com / diagnostics_italy@bio-rad.com Information department: Technical services, customer support. lsg_info_it@bio-rad.com / diagnostics_italy@bio-rad.com 1.4 Emergency telephone number: active during office hours for technical information * SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 The substance is not classified according to the CLP regulation. 2.2 Label elements Labelling according to Regulation (EC) No 1272/2008 Void Hazard pictograms Void Signal word Void Hazard statements Void Precautionary statements P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P280 Wear protective clothing / eye protection. P402 Store in a dry place. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. 2.3 Other hazards Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable. * SECTION 3: Composition/information on ingredients 3.1 Chemical characterisation: Substances CAS No. Description: Polyvinylidene fluoride (Contd. on page 2)

16 Page 2/6 Trade name: Trans-Blot Turbo PVDF Membrane Identification number(s): Index number: Additonal information: For the wording of the listed risk phrases refer to section 16. (Contd. of page 1) SECTION 4: First aid measures 4.1 Description of first aid measures After inhalation Supply fresh air; consult doctor in case of complaints. After skin contact Generally the product does not irritate the skin. After eye contact Rinse opened eye for several minutes under running water. After swallowing Induce vomiting and call for medical help. 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available. 4.3 Indication of any immediate medical attention and special treatment needed No further relevant information available. * SECTION 5: Firefighting measures 5.1 Extinguishing media Suitable extinguishing agents CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. 5.2 Special hazards arising from the substance or mixture No further relevant information available. 5.3 Advice for firefighters Protective equipment: No special measures required. * SECTION 6: Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures Wear protective clothing. 6.2 Environmental precautions: No special measures required. 6.3 Methods and material for containment and cleaning up: Pick up mechanically. 6.4 Reference to other sections No dangerous substances are released. See Section 7 for information on safe handling See Section 8 for information on personal protection equipment. See Section 13 for disposal information. * SECTION 7: Handling and storage 7.1 Precautions for safe handling No special measures required. Information about protection against explosions and fires: No special measures required. 7.2 Conditions for safe storage, including any incompatibilities Storage Requirements to be met by storerooms and receptacles: According to product specification Information about storage in one common storage facility: Not required. Further information about storage conditions: None. (Contd. on page 3)

17 Page 3/6 Trade name: Trans-Blot Turbo PVDF Membrane 7.3 Specific end use(s) No further relevant information available. (Contd. of page 2) SECTION 8: Exposure controls/personal protection Additional information about design of technical systems: No further data; see item Control parameters Components with limit values that require monitoring at the workplace: Not required. Additional information: The lists that were valid during the creation were used as basis. 8.2 Exposure controls Personal protective equipment General protective and hygienic measures The usual precautionary measures should be adhered to when handling chemicals. Protection of hands: Protective gloves. Material of gloves Synthetic gloves Penetration time of glove material The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be observed. Eye protection: Safety glasses SECTION 9: Physical and chemical properties 9.1 Information on basic physical and chemical properties General Information Appearance: Form: Solid material. Colour: Whitish Odour: Odourless Odour threshold: ph-value: Not applicable. Change in condition Melting point/melting range: 230 C Boiling point/boiling range: undetermined Flash point: Not applicable Flammability (solid, gaseous) Product is not flammable. Ignition temperature: Decomposition temperature: Self igniting: Danger of explosion: Product does not present an explosion hazard. Explosion limits: Lower: Upper: Vapour pressure: Not applicable. Density at 20 C: 1,65 g/cm³ (Contd. on page 4)

18 Page 4/6 Trade name: Trans-Blot Turbo PVDF Membrane Relative density Vapour density Not applicable. Evaporation rate Not applicable. Solubility in / Miscibility with Water: Fully miscible Partition coefficient (n-octanol/water): Viscosity: dynamic: Not applicable. kinematic: Not applicable. Organic solvents: 0,0 % Solids content: 100,0 % 9.2 Other information No further relevant information available. (Contd. of page 3) SECTION 10: Stability and reactivity 10.1 Reactivity 10.2 Chemical stability Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications Possibility of hazardous reactions No dangerous reactions known 10.4 Conditions to avoid No further relevant information available Incompatible materials: No further relevant information available Hazardous decomposition products: No dangerous decomposition products known * SECTION 11: Toxicological information 11.1 Information on toxicological effects Acute toxicity: Primary irritant effect: on the skin: No irritant effect. on the eye: No irritating effect. Sensitisation: No sensitising effects known. Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us. The substance is not subject to classification according to the latest version of the EU lists. SECTION 12: Ecological information 12.1 Toxicity Aquatic toxicity: No further relevant information available Persistence and degradability No further relevant information available Bioaccumulative potential No further relevant information available Mobility in soil No further relevant information available. Additional ecological information: General notes: Generally not hazardous for water. (Contd. on page 5)

19 Page 5/6 Trade name: Trans-Blot Turbo PVDF Membrane 12.5 Results of PBT and vpvb assessment PBT: Not applicable. vpvb: Not applicable Other adverse effects No further relevant information available. (Contd. of page 4) SECTION 13: Disposal considerations 13.1 Waste treatment methods Recommendation Hand over to hazardous waste disposers. Must not be disposed of together with household garbage. Do not allow product to reach sewage system. Uncleaned packagings: Recommendation: Disposal must be made according to official regulations. SECTION 14: Transport information 14.1 UN-Number ADR, ADN, IMDG, IATA Void 14.2 UN proper shipping name ADR, ADN, IMDG, IATA Void 14.3 Transport hazard class(es) ADR, ADN, IMDG, IATA Class Void 14.4 Packing group ADR, IMDG, IATA Void 14.5 Environmental hazards: Marine pollutant: No 14.6 Special precautions for user Not applicable Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code UN "Model Regulation": - Not applicable. * SECTION 15: Regulatory information 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture National regulations Water hazard class: Generally not hazardous for water Chemical safety assessment: A Chemical Safety Assessment has not been carried out. (Contd. on page 6)

20 Page 6/6 Trade name: Trans-Blot Turbo PVDF Membrane (Contd. of page 5) SECTION 16: Other information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. Department issuing SDS: Environmental Health and Safety. Contact: Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) Abbreviations and acronyms: ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage of Dangerous Goods by Road) IMDG: International Maritime Code for Dangerous Goods IATA: International Air Transport Association GHS: Globally Harmonised System of Classification and Labelling of Chemicals CAS: Chemical Abstracts Service (division of the American Chemical Society) * Data compared to the previous version altered.

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