1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING

Transcription

1 SIGMA-ALDRICH SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 Version 3.2 Revision Date Print Date IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING Product name : Aniline Product Number : Brand : Sigma-Aldrich Company : Sigma-Aldrich Company Ltd. The Old Brickyard NEW ROAD, GILLINGHAM Dorset SP8 4XT UNITED KINGDOM Telephone : Fax : Emergency Phone # : +44 (0) address : eurtechserv@sial.com 2. HAZARDS IDENTIFICATION Risk advice to man and the environment Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Risk of serious damage to eyes. May cause sensitization by skin contact. Toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed. Possible risk of irreversible effects. Very toxic to aquatic organisms. 3. COMPOSITION/INFORMATION ON INGREDIENTS Formula : C 6 H 7 N Molecular Weight : g/mol CAS-No. EC-No. Index-No. Classification Concentration Aniline T, N, Carc.Cat.3, Mut.Cat.3, R23/24/25 - R40 - R41 - R43 - R48/23/24/25 - R68 - R50-4. FIRST AID MEASURES General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Sigma-Aldrich Page 1 of 5

2 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special protective equipment for fire-fighters Wear self contained breathing apparatus for fire fighting if necessary. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods for cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. 7. HANDLING AND STORAGE Handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. Keep away from sources of ignition - No smoking. Take measures to prevent the build up of electrostatic charge. Storage Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Handle under inert gas. Protect from moisture. Light sensitive. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Components with workplace control parameters Components CAS-No. Value Control parameters Aniline TWA 1 ppm 4 mg/m3 Update Basis UK. EH40 Occupational Exposure Limits Remarks Can be absorbed through skin. The assigned substances are those for which there are concerns that dermal absorption will lead to systemic toxicity. Where no specific short-term exposure limit is listed, a figure three times the long-term exposure should be used Personal protective equipment Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multipurpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Handle with gloves. Sigma-Aldrich Page 2 of 5

3 Eye protection Safety glasses Skin and body protection Choose body protection according to the amount and concentration of the dangerous substance at the work place. Hygiene measures Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form liquid Safety data ph 8.8 at 36 g/l at 20 C Melting point -6 C Boiling point 184 C Flash point Ignition temperature 540 C Lower explosion limit Upper explosion limit 70 C - closed cup 1.3 %(V) 23 %(V) Vapour pressure 0.49 hpa at 20 C 0.8 hpa at 20 C Density g/ml at 25 C Water solubility Partition coefficient: n-octanol/water Relative vapour density soluble log Pow: (Air = 1.0) 10. STABILITY AND REACTIVITY Storage stability Stable under recommended storage conditions. Conditions to avoid Avoid moisture. Materials to avoid Oxidizing agents, Iron and iron salts., Zinc Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx) Thermal decomposition 190 C 11. TOXICOLOGICAL INFORMATION Acute toxicity LD50 Oral - rat mg/kg Sigma-Aldrich Page 3 of 5

4 LC50 Inhalation - mouse - 4 h ppm LD50 Dermal - rabbit mg/kg Irritation and corrosion Skin - rabbit - Skin irritation - 24 h Eyes - rabbit - Severe eye irritation Sensitisation May cause allergic skin reaction. Chronic exposure This product is or contains a component that has been reported to be possibly carcinogenic based on its IARC, ACGIH, NTP, or EPA classification. IARC: 3 - Group 3: Not classifiable as to its carcinogenicity to humans (Aniline) Laboratory experiments have shown mutagenic effects. Signs and Symptoms of Exposure Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes cyanosis. Onset may be delayed 2 to 4 hours or longer., Cyanosis, Headache, Vomiting, Nausea, Incoordination., fatigue, Dizziness, Drowsiness, Confusion., Weakness, Unconsciousness, Symptoms may be delayed. Potential Health Effects Inhalation Toxic if inhaled. May cause respiratory tract irritation. Skin Toxic if absorbed through skin. May cause skin irritation. Eyes Causes serious eye irritation. Ingestion Toxic if swallowed. Target Organs Blood, Bladder, Kidney, Central nervous system, Additional Information RTECS: BW ECOLOGICAL INFORMATION Elimination information (persistence and degradability) Biodegradability Ecotoxicity effects Toxicity to fish Toxicity to daphnia and other aquatic invertebrates. LC50 - Oncorhynchus mykiss (rainbow trout) mg/l - 96 h EC50 - Daphnia magna (Water flea) mg/l - 48 h Toxicity to algae EC50 - SELENASTRUM - 19 mg/l - 72 h Further information on ecology Very toxic to aquatic organisms. 13. DISPOSAL CONSIDERATIONS Product This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service to dispose of this material. Sigma-Aldrich Page 4 of 5

5 Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION ADR/RID UN-Number: 1547 Class: 6.1 Proper shipping name: ANILINE Packing group: II IMDG UN-Number: 1547 Class: 6.1 Packing group: II EMS-No: F-A, S-A Proper shipping name: ANILINE Marine pollutant: No IATA UN-Number: 1547 Class: 6.1 Proper shipping name: Aniline Packing group: II 15. REGULATORY INFORMATION Labelling according to EC Directives EC Label Hazard symbols T Toxic N Dangerous for the environment R-phrase(s) R23/24/25 Toxic by inhalation, in contact with skin and if swallowed. R40 Limited evidence of a carcinogenic effect. R41 Risk of serious damage to eyes. R43 May cause sensitization by skin contact. R48/23/24/25 Toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed. R68 Possible risk of irreversible effects. R50 Very toxic to aquatic organisms. S-phrase(s) S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 Take off immediately all contaminated clothing. S36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S46 If swallowed, seek medical advice immediately and show this container or label. S61 Avoid release to the environment. Refer to special instructions/ Safety data sheets. S63 In case of accident by inhalation: remove casualty to fresh air and keep at rest. 16. OTHER INFORMATION Further information Copyright 2009 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Co., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. Sigma-Aldrich Page 5 of 5