SAFETY DATA SHEET. 1. Identification of the substance/mixture and of the company/undertaking. BrightStar(R) Psoralen Biotin

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1 SAFETY DATA SHEET 1. Identification of the substance/mixture and of the company/undertaking Identification of the substance/preparation Product name BrightStar(R) Psoralen Biotin Company/Undertaking Identification Life Technologies 5791 VAN ALLEN WAY PO BOX 6482 CARLSBAD, CA INVITROGEN CORPORATION NEW ZEALAND LIMITED BOTHA ROAD PENROSE AUCKLAND 1006 PAR NEW ZEALAND INVITROGEN AUSTRALIA PTY LIMITED COMPARK CIRCUIT MULGRAVE VIC hour Emergency Response (Transport): Outside of the U.S For research use only. Not intended for human or animal diagnostic or therapeutic uses. Australian MSDS Statement 2. Hazards identification Classified as hazardous according to criteria of Worksafe Australia. Hazardous Substance. Dangerous Goods. GHS - Classification Signal word Danger Page 1 / 6

2 Health hazard Acute oral toxicity Category 4 Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 1 Specific target organ systemic toxicity (single exposure) Category 3 Physical hazards H226 - Flammable liquid and vapour. Hazard statements H226 - Flammable liquid and vapour H302 - Harmful if swallowed H335 - May cause respiratory irritation H315 - Causes skin irritation H318 - Causes serious eye damage H336 - May cause drowsiness and dizziness Precautionary statements P301 + P312 - IF SWALLOWED: Call a POISON CENTRE or doctor/physician if you feel unwell P303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P332 + P313 - If skin irritation occurs: Get medical advice/attention P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P304 + P340 - IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing P312 - Call a POISON CENTRE or doctor/physician if you feel unwell P210 - Keep away from heat/sparks/open flames/hot surfaces. - No smoking P233 - Keep container tightly closed P240 - Ground/bond container and receiving equipment P241 - Use explosion-proof electrical/ventilating/lighting/.?/ equipment P242 - Use only non-sparking tools P243 - Take precautionary measures against static discharge P280 - Wear protective gloves/protective clothing/eye protection/face protection P264 - Wash hands thoroughly after handling P261 - Avoid breathing dust/fume/gas/mist/vapours/spray P271 - Use only outdoors or in a well-ventilated area European Union Page 2 / 6

3 EU Specific Hazard Statements R-phrase(s) R10 - Flammable R22 - Harmful if swallowed R41 - Risk of serious damage to eyes R67 - Vapours may cause drowsiness and dizziness R36/37 - Irritating to eyes and respiratory system. S-phrase(s) S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S46 - If swallowed, seek medical advice immediately and show this container or label S 7/9 - Keep container tightly closed and in a well-ventilated place S37/39 - Wear suitable gloves and eye/face protection. Principle Routes of Exposure/ Potential Health effects Eyes Skin Inhalation Ingestion Specific effects Carcinogenic effects Mutagenic effects Reproductive toxicity Sensitisation Target Organ Effects Risk of serious damage to eyes. Irritating to eyes. May cause skin irritation in susceptible persons. May cause irritation of respiratory tract. May be harmful by inhalation. Harmful if swallowed. Eyes Skin Respiratory system Central nervous system (CNS) 3. COMPOSITION/INFORMATION ON INGREDIENTS CAS-No. EINECS-No. Weight percent n-butyl alcohol We recommend handling all chemicals with caution. 4. FIRST AID MEASURES Skin contact Wash off immediately with plenty of water. Consult a physician. Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Consult a physician. Ingestion Never give anything by mouth to an unconscious person. Call a physician or Poison Control Centre immediately. Call a POISON CENTRE or doctor/physician if exposed or you feel unwell. Inhalation Move to fresh air. If not breathing, give artificial respiration. Consult a physician. Page 3 / 6

4 Notes to physician Treat symptomatically. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Special protective equipment for firefighters Dry chemical. Wear self-contained breathing apparatus and protective suit. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Methods for cleaning up Use personal protective equipment. Avoid contact with skin, eyes and clothing. Remove all sources of ignition. Soak up with inert absorbent material. Environmental precautions Prevent further leakage or spillage if safe to do so. See Section 12 for additional information. 7. HANDLING AND STORAGE Handling Storage Avoid contact with skin, eyes and clothing. Avoid contact with skin and eyes. Keep away from heat, sparks and open flame. No smoking. Keep in properly labelled containers. Keep container tightly closed in a dry and well-ventilated place. 8. Exposure controls/personal protection Exposure limits Engineering measures Ensure adequate ventilation, especially in confined areas. Personal protective equipment Respiratory protection In case of insufficient ventilation wear suitable respiratory equipment. Hand protection Eye protection Skin and body protection Hygiene measures Environmental exposure controls Impervious gloves. Safety glasses with side-shields. Lightweight protective clothing. Handle in accordance with good industrial hygiene and safety practice. Prevent product from entering drains. General Information Form Appearance 9. PHYSICAL AND CHEMICAL PROPERTIES liquid colourless Page 4 / 6

5 Odour strong, characteristic, Alcohol Boiling Point/Range C 117 F 243 Melting point/range C -89 F -129 Flash point C 29 F 84 Autoignition temperature C No data available F No data available oxidising properties No information available Water solubility No data available 10. STABILITY AND REACTIVITY Stability Materials to avoid Hazardous decomposition products polymerisation Stable under normal conditions. Fire Hazard Strong oxidising agents. Strong acids. Alkali metals Halogenated compounds. No information available Hazardous polymerisation does not occur. 11. Toxicological information Acute toxicity LD50 (oral,rat/mouse) LD50 (dermal,rat/rabbit) LC50 (inhalation,rat/mouse) n-butyl alcohol = 790 mg/kg (Rat) No data available =8000ppm(Rat) >17.7mg/L(Rat) Principle Routes of Exposure/ Potential Health effects Eyes Skin Inhalation Ingestion Target Organ Effects Risk of serious damage to eyes. Irritating to eyes. May cause skin irritation in susceptible persons. May cause irritation of respiratory tract. May be harmful by inhalation. Harmful if swallowed. Eyes Skin Respiratory system Central nervous system (CNS) 12. ECOLOGICAL INFORMATION Ecotoxicity effects Mobility Biodegradation Bioaccumulation Daphnia magna (Water flea) see log Pow No information available. No information available n-butyl alcohol Freshwater Algae Data Desmodesmus subspicatus EC50>500 mg/l (96 h) Desmodesmus subspicatus EC50>500 mg/l (72 h) Water Flea Data Daphnia magna EC50=1983 mg/l (48 h) Daphnia magna EC mg/l (48 h) Freshwater Fish Species Data Microtox Data log Pow logpow DISPOSAL CONSIDERATIONS Page 5 / 6

6 Dispose of in accordance with local regulations. 14. TRANSPORT INFORMATION IATA Proper shipping name Butanols Hazard class 3 Subsidiary Class None Packing group II UN-No UN Regulatory information International Inventories EINECS ELINCS ENCS PICCS TSCA n-butyl alcohol Listed - Listed Listed Listed China AICS KECL DSL NDSL n-butyl alcohol Listed Listed Listed Listed - Industrial Safety and Health Law: Toxic Chemicals Control Law Japan Industrial Safety and Health Law: Korea 16. OTHER INFORMATION Reason for Revision (M)SDS sections updated For research use only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unkown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE. End of Safety Data Sheet Page 6 / 6

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