SAFETY DATA SHEET Santa Cruz Biotechnology, Inc. Revision date 22-Sep-2014 Version 1.1

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1 SAFETY DATA SHEET Santa Cruz Biotechnology, Inc. Version PRODUCT AND COMPANY IDENTIFICATION Product Name Product Code Recommended use Company Santa Cruz Biotechnology, Inc Finnell Street Dallas, TX Bromo-2,2-dimethylpropane SC For research use only. Not intended for diagnostic or therapeutic use. Emergency telephone number Chemtrec (Within USA) (Outside USA) 2. HAZARDS IDENTIFICATION Signal word Emergency Overview CAUTION Irritating to respiratory system May cause skin irritation and/or dermatitis Vapors may be irritating to eyes, nose, throat, and lungs OSHA Regulatory Status This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ) Potential health effects Principle Routes of Exposure Eyes Skin Inhalation Ingestion Chronic Toxicity Inhalation Skin Contact Eye contact Irritating to eyes. May cause irritation. Irritating to skin. May cause inflammation. Irritating to respiratory system. May cause irritation of respiratory tract. Ingestion may cause irritation to mucous membranes. Avoid repeated exposure. Hazards not otherwise classified (HNOC) Hazards not otherwise classified (HNOC) Not applicable Environmental Hazard See Section 12: ECOLOGICAL INFORMATION. NFPA Health hazards 2 Flammability 3 Instability 0 Physical and chemical - properties HMIS Health hazards 2 Flammability 3 Physical hazards 0 Personal protection X Page 1 / 6

2 3. COMPOSITION/INFORMATION ON INGREDIENTS Product Name 1-Bromo-2,2-dimethylpropane Molecular Weight Formula C5H11Br 4. FIRST AID MEASURES General advice Eye contact Skin Contact Inhalation Ingestion Note to physicians Self-protection of the first aider Immediate medical attention is required. In case of accident or unwellness, seek medical advice immediately (show directions for use or safety data sheet if possible). If symptoms persist, call a physician. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. If symptoms persist, call a physician. Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. Wash off immediately with plenty of water. Wash contaminated clothing before reuse. If skin irritation persists, call a physician. Immediate medical attention is not required. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Remove to fresh air. If symptoms persist, call a physician. Artificial respiration and/or oxygen may be necessary. Call a physician. Immediate medical attention is not required. Move to fresh air in case of accidental inhalation of vapors. Immediate medical attention is not required. Rinse mouth. Drink plenty of water. Do NOT induce vomiting. Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Call a physician. Treat symptomatically. Remove all sources of ignition. Use personal protective equipment as required. 5. FIRE-FIGHTING MEASURES Suitable Extinguishing Media Suitable Extinguishing Media Dry chemical, CO2, water spray or alcohol-resistant foam. Specific hazards arising from the chemical Flammable properties HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Flash point C 7 CC (closed cup) Hazardous combustion products Carbon oxides. Explosion data Sensitivity to Mechanical Impact Sensitivity to Static Discharge.. Protective equipment and precautions for firefighters Protective equipment and precautions As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH for firefighters (approved or equivalent) and full protective gear. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Remove all sources of ignition. Evacuate personnel to safe areas. Ensure adequate ventilation, especially in confined areas. Use personal protective equipment as required. Keep people away from and upwind of spill/leak. Page 2 / 6

3 Environmental precautions Prevent further leakage or spillage if safe to do so. Prevent product from entering drains. Do not flush into surface water or sanitary sewer system. See Section 12 for additional Ecological Information. Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Pick up and transfer to properly labeled containers. Dam up. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Soak up with inert absorbent material. 7. HANDLING AND STORAGE Advice on safe handling Storage Conditions Ensure adequate ventilation, especially in confined areas. Keep away from heat, sparks, flame and other sources of ignition (i.e., pilot lights, electric motors and static electricity). Take precautionary measures against static discharges. Use spark-proof tools and explosion-proof equipment. All equipment used when handling the product must be grounded. Use with local exhaust ventilation. Use personal protective equipment as required. Do not breathe dust/fume/gas/mist/vapors/spray. Keep tightly closed in a dry and cool place. Keep in properly labeled containers. Keep containers tightly closed in a cool, well-ventilated place. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Exposure controls Engineering Controls Showers Eyewash stations Ventilation systems Personal protective equipment (PPE) Eye/face protection Tight sealing safety goggles. Face protection shield. Skin and Body Protection Antistatic footwear. Wear fire/flame resistant/retardant clothing. Gloves made of plastic or rubber. Suitable protective clothing. Apron. Respiratory protection Ensure adequate ventilation, especially in confined areas. General Hygiene Considerations When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended. 9. PHYSICAL AND CHEMICAL PROPERTIES Physical State Appearance Odor liquid Property Values ph Melting point/freezing point C Boiling point 105 C Flash point 7 C CC (closed cup) Density 1.20 g/ml Evaporation rate Upper flammability limits Lower flammability limit Vapor pressure 31.0 Vapor density Specific gravity 1.20 Water solubility Solubility in other solvents Partition coefficient 3.03 Autoignition temperature Page 3 / 6

4 Decomposition temperature Kinematic viscosity Explosive properties Oxidizing properties 10. STABILITY AND REACTIVITY Reactivity Stability Incompatible materials Conditions to avoid Hazardous Decomposition Products Hazardous polymerization Not applicable Stable under recommended storage conditions. Incompatible with oxidizing agents. Heat, flames and sparks. Carbon oxides. Hazardous polymerization does not occur 11. TOXICOLOGICAL INFORMATION Acute toxicity Product Information Chronic Toxicity Chronic Toxicity Target Organ Effects Product does not present an acute toxicity hazard based on known or supplied information. Avoid repeated exposure. None known. 12. ECOLOGICAL INFORMATION Ecotoxicity Ecotoxicity Persistence and degradability Bioaccumulation The environmental impact of this product has not been fully investigated DISPOSAL CONSIDERATIONS Disposal considerations Contaminated packaging Disposal should be in accordance with applicable regional, national and local laws and regulations. Do not reuse container. 14. TRANSPORT INFORMATION DOT UN/ID no UN1993 Hazard Class 3 Packing Group II Proper shipping name Flammable liquids, n.o.s. Description UN1993, Flammable liquids, n.o.s. (1-Bromo-2,2-dimethylpropane), 3, II Emergency Response Guide Number 128 IATA UN/ID no UN1993 Hazard Class 3 Packing Group II Page 4 / 6

5 Proper shipping name Flammable liquid, n.o.s. Description UN1993, Flammable liquid, n.o.s. (1-Bromo-2,2-dimethylpropane), 3, II Special Provisions A3 IMDG UN/ID no UN1993 Hazard Class 3 Packing Group II Proper shipping name Flammable liquid, n.o.s. Description UN1993, Flammable liquid, n.o.s. (1-Bromo-2,2-dimethylpropane), 3, II, (7 C c.c.) EmS-No F-E, S-E 15. REGULATORY INFORMATION International Inventories X - Listed TSCA - United States Toxic Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances PICCS - Philippines Inventory of Chemicals and Chemical Substances US Federal Regulations SARA 313 Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372. SARA 311/312 Hazard Categories Acute health hazard Yes Chronic Health Hazard No Fire hazard Yes Sudden release of pressure hazard No Reactive hazard No CWA (Clean Water Act) This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR and 40 CFR ). US State Regulations California Proposition 65 This product does not contain any Proposition 65 chemicals. U.S. State Right-to-Know Regulations This product does not contain any substances regulated by state right-to-know regulations Mexico Regulatory Information Mexico - Grade Serious risk, Grade 3 Canada Regulatory Information This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR Page 5 / 6

6 WHMIS Hazard Class B2 - Flammable liquid 16. OTHER INFORMATION Revision date 22-Sep-2014 Revision note Disclaimer The information provided in this Material Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. End of Safety Data Sheet Page 6 / 6

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