SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING

Transcription

1 SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY/UNDERTAKING PRODUCT NAME: PRODUCTNUMBER : 2X QPCR MASTER MIX F1024G KIT NAME: KIT PART NUMBER: TAQMAN MAP (JOHNE'S) REAGENTS SUPPLIER: APPLIED BIOSYSTEMS 7 KINGSLAND GRANGE, WOOLSTON WARRINGTON, CHESHIRE, WA1 4SR, UNITED KINGDOM IN CASE OF EMERGENCY CALL CHEMTREC COMPOSITION/INFORMATION ON INGREDIENTS EC-No. Hazardous components CAS-No. (EINECS-No.) Weight % Classification Tris Base % Xi R36/38 POLYSORBATE 20 TWEEN % Xi R36/37/38 (POLYOXYETHYLENE SORBITAN Glycerol % Xi R36/37/38 3. HAZARDS IDENTIFICATION European Union Classification: Xi R-phrase(s) R36/37/38 Irritating to eyes, respiratory system and skin. S-phrase(s) Page 1 of 6 Revision Date:

2 4. FIRST AID MEASURES Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention immediately. Inhalation Skin contact Ingestion Move to fresh air. Give oxygen or artificial respiration if not breathing Get medical attention immediately. Wash off immediately with plenty of water. Remove and wash contaminated clothing before re-use. Get medical attention immediately. If swallowed, seek medical advice immediately and show this container or label. Never give anything by mouth to an unconscious person. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Water spray Carbon dioxide (CO2) Foam Dry chemical Hazardous decomposition products Special protective equipment for fire-fighters Carbon oxides Wear self contained breathing apparatus for fire fighting if necessary. Use personal protective equipment. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Avoid Inhalation. Environmental precautions Should not be released into the environment. Methods for cleaning up Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local/national regulations (see section 13). 7. HANDLING AND STORAGE Precautions for safe handling Use only in area provided with appropriate exhaust ventilation. Wear personal protective equipment. Page 2 of 6 Revision Date:

3 Storage conditions Protect against physical damage. Isolate from incompatible substances. Store in original container. See product label for specific storage requirements. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Exposure limit(s) Hazardous components Regulation Type of listing Value Glycerol United Kingdom STELmist 30 mg/m3 United Kingdom TWAmist 10 mg/m3 Hazardous components Regulation Type of listing Value SODIUM AZIDE United Kingdom STEL 0.3 mg/m3, NaN3 United Kingdom TWA 0.1 mg/m3, NaN3 European Union - STEL 0.3 mg/m3 IOELVs European Union - IOELVs TWA 0.1 mg/m3 Eye protection Use appropriate safety glasses with side-shields or chemical safety goggles. Ensure that eyewash stations and safety showers are close to the workstation location. Hand protection Respiratory protection Skin protection Engineering measures Impervious gloves should be worn to prevent skin contact and absorption. Contact glove provider for specific recommendations. Avoid breathing vapor. When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. For unknown concentrations or Immediately Dangerous to Life or Health (IDLH), use a full-facepiece positive pressure air supplied respirator. Wear suitable protective clothing. Use adequate exhaust ventilation or other engineering controls to maintain airborne concentrations below occupational exposure limit 9. PHYSICAL AND CHEMICAL PROPERTIES Physical state liquid Colour Odour Odour Odour Threshold ph 7.8 Boiling point Melting point Vapour pressure Water solubility Flash point Explosion limits Density Percent volatile Volatile organic compounds (VOC) content Page 3 of 6 Revision Date:

4 10. STABILITY AND REACTIVITY Conditions to avoid Keep away from open flames, hot surfaces and sources of ignition. Materials to avoid Hazardous decomposition products Strong acids and oxidizing agents, Acetic anhydride, Isocyanates, Amines, Permanganates, Strong basesstrong bases, Oxidizing agents Carbon oxides 11. TOXICOLOGICAL INFORMATION Hazardous components : Tris Base Acute oral toxicity Oral LD50 rat 5,900 mg/kg Hazardous components : POLYSORBATE 20 TWEEN-20 (POLYOXYETHYLENE SORBITAN Acute oral toxicity LD50 rat µl/kg Hazardous components : Glycerol Acute oral toxicity Acute inhalation toxicity Acute dermal toxicity LD50 rat 12,600 mg/kg LC50 rat 1 h > 570 mg/m3 LD50 rat > 21,900 mg/kg Further information The toxicological properties of this product have not been thoroughly investigated. Use appropriate precautions. 12. ECOLOGICAL INFORMATION We have no quantitative data concerning the ecological effects of this product. An environmental hazard cannot be excluded in the event of unprofessional handling or disposal. Glycerol Ecotoxicity effects Toxicity to fish Toxicity to daphnia LC50 Oncorhynchus mykiss (rainbow trout) 96 h 51,000-57,000 mg/l EC50 Daphnia magna (Water flea) 24 h > 500 mg/l Page 4 of 6 Revision Date:

5 13. DISPOSAL CONSIDERATIONS Environmental precautions Disposal methods General advice Should not be released into the environment. Dispose of in accordance with local regulations. DISPOSAL CONSIDERATIONS The product has to be disposed of as laboratory chemical in accordance with local regulations. 14. TRANSPORT INFORMATION IATA-DGR Not dangerous goods IMDG ADR Not dangerous goods Not dangerous goods 15. REGULATORY INFORMATION Labelling Hazard symbol(s) and indication(s) of danger for dangerous substances and preparations Xi: R-phrase(s) R36/37/38 Irritating to eyes, respiratory system and skin. Page 5 of 6 Revision Date:

6 National Inventory Status - European Union EUROPEAN INVENTORY OF EXISTING CHEMICAL SUBSTANCES (EINECS) All components of this product are NOT included on the European Inventory of Existing Chemical Substances (EINECS). Hazardous components POLYSORBATE TWEEN-20 (POLYOXYETHYLENE SORBITAN 2-DEOXY TTP dctp Oligonucleotide Mixture EUROPEAN NO-LONGER POLYMERS LIST (NLP) This product contains components on the European No-Longer-Polymer (NLP) list. Hazardous components POLYSORBATE TWEEN-20 (POLYOXYETHYLENE SORBITAN EUROPEAN LIST OF NOTIFIED CHEMICAL SUBSTANCES (ELINCS) No components of this product are included on the European List of Notified Chemical Substances (ELINCS). 16. OTHER INFORMATION Disclaimer: This MSDS has been prepared using information from sources considered technically reliable. It should not be relied upon as a product specification. The company makes no warranty of any kind, expressed or implied, concerning the safe use of this material in your process or in combination with other chemical substances. Every user of the product is responsible for evaluating its own processes and conditions of use and selecting appropriate protective measures for employee exposure. Text of R-phrases mentioned in Section 2 R36/37/38 Irritating to eyes, respiratory system and skin. R36/38 Irritating to eyes and skin. Document no Print Date 11/21/2009 2:31:00 PM Page 6 of 6 Revision Date: