Venue - Accomodation. How to get there. Hotel Zuiderduin. Shuttle bus. From the Centraal Station. From the airport

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Venue - Accomodation Hotel Zuiderduin Zeeweg 52-1931 VL Egmond aan Zee Nederland Tel.: +31 (0)72-750 2000 http://www.zuiderduin.nl/ All Summer school sessions, the ESTIV conference and the Satellite meetings will take place in the same hotel. The participants will thus be able to benefit from the presence of more than 400 attendees. How to get there Shuttle bus Egmond aan Zee is situated around 45 km from Amsterdam and does not have its train station. COACH facilitates the transport of the Summer school participants by organising two shuttle buses going from the Amsterdam Centraal s tation to Egmond on Saturday evening at 20.00 and on Sunday morning at 11.30. The coach will be waiting in front of the Victoria Hotel just outside of the Amsterdam Central train station, you should see the SEURAT-1 logo nearby. If you wish to get to Egmond by public transportation on your own, follow the instructions below: From the Centraal Station Take a train from Centraal Station to Alkmaar (40 min, 7,20 full-fare one way). In Alkmaar, take a bus n 165 to Egmond aan Zee, stop Zeeweg (30 min, 3,50 one way). The hotel is in front of the bus station. From the airport Take a train from Schiphol train station to Alkmaar ( 9.00 full-fare, one way). You will have to change the train at Amsterdam Sloterdjik. In Alkmaar, take a bus n 165 to Egmond aan Zee, stop Zeeweg (30 min, 3,50 one way). The hotel is in front of the bus station. Stop Zeeweg Amsterdam Sloterdijk Station Bus n 165 Centraal Station Need a Taxi? If in any case you need a taxi, we advise you to call the local company called Taxi Zwart: +31 72 533 13 13 centrale@taxizwart.nl Schiphol Airport 2

Hotel Plan Parallel Sessions Poster Session

522 Room: Abdijzaal Lounge 2 Abdijzaal Room: Abdijzaal Summer School Programme Abdijzaal 522 Day 1: 8 June 2014 12:30 Lunch 13:30 Welcome word SEP member 13:45 Introduction to Adverse Outcome Pathways (AOPs) for Toxicity: Description, Practical Application and Use Marc Cronin (COSMOS) 14:30 Development of a liver bioreactor Yaakov Nahmias (HeMiBio) 15:15 Coffee break 15:45 16:30 In vitro systems for metabolism studies: from S9 to 3D culture systems Epigenetics in in vitro toxicology: Principles, technology, data analyses, and challenges. Jan Hengstler (NOTOX) 17:15 Experimental Design of in vitro assays TBC (ToxBank) 18:00 End of day 1 19:00 Common dinner Simone van Breda (DETECTIVE) 20:00 Bowling Day 2: 9 June 2014 9:00 In vitro/in vivo extrapolation strategies Bas Blaauboer (ESTIV) 9:45 Toxicological Data Resources: The Basis of Computational Modelling and Safety Assessment 10:30 Coffee break Andrea Richarz (COSMOS) 10:45 Computational Approaches to Toxicity Prediction: Introduction to Grouping, Category Formation and Read- Across Marc Cronin (COSMOS) 11:30 TTC for cosmetics and beyond Sue Barlow (COSMOS) 12:15 Toxicity Prediction based on MoA knowledge Alfonso Lostia (COACH) 13:00 Lunch PARALLEL SESSIONS: SOFT SKILLS & HANDS-ON Time Parallel Session 1 Parallel Session 2 14:00 Pathway analysis and visualization, ToxBank Scientific Method, Christian Pinset (SCR&Tox) 15:00 Hands-on training on ToxWiz software for the analysis of high-throughput omics data, Dragana Mitic Potkrajac (NOTOX) 16:00 Coffee break How to write a scientific paper & Presentation techniques, A. Braeuning 16:30 Scientific Method, Christian Pinset (SCR&Tox) 17:30 How to write a scientific paper & Presentation techniques, A. Braeuning Modelling Toxicokinetics & Toxicodynamics, Alicia Paini (COSMOS) 18:30 Cocktail, Poster session I Day 3: 10 June 2014 in parallel to the NOTOX satellite meeting Time Topic 9:00 Poster session II, networking & coffee 11:30 Shuttle bus to Amsterdam Centraal Station Day 4: 11 June 2014 embedded in the programme of the ESTIV conference 16:30 18:00 Job opportunities and career exploration Academia: Greet Schoeters and Bas Blaauboer Industry: Laura Suter-Dick and Erwin Roggen Regulatory bodies: TBC

Additional information Registrations Welcome desk: Badges Drop printed documents: flyers, posters Get logistic information Sunday 8 June: Registration at the Welcome desk starting from 10.00 The Summer school will start at 13.30 Contacts Please, contact the COACH Office at: coach-office@eurtd.com Sara Vinklatova Phone office : +33 (0)1 53 94 54 86 On site: +33 (0)6 77 88 71 10 Social events Sunday 8 June: 12.30 to 13.30: Get-together-lunch 19.00: Common dinner 20.00: Bowling Monday 9 June: 13.00 to 14.00: Lunch 18.30 to 19.30: Cocktail during the Poster session (1 st part) No social event for dinner has been planned Tuesday 10 June: 9.00 to 11.30: 2 nd part of the Poster session, coffee and cakes Restaurants 1-Restaurant Van Speijk (French) Westeinde 1 1931 AB Egmond aan Zee Phone +31 72-5071703 info@restaurantvanspeijk.nl 2-D'Oude Clipper (fish restaurant) Smidstraat 3 1931 EX Egmond aan Zee Phone: +31 72-5061600 http://www.oudeclipper.nl/ 3-Mats (Dutch) Pompplein 11 1931 AD, Egmond aan Zee Phone: +31 72-5316206 Info@restaurant-mats.nl 4-Angelo's (Italian) Pompplein 3 1931 AD Egmond aan Zee Phone: +31 72-7431422 http://www.angelosrestaurant.nl/ 2 1 4 3 Hotel 5