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SAFETY DATA SHEET 1. Identification of the substance/mixture and of the company/undertaking Identification of the substance/preparation Product name RPMI 1640 Company/Undertaking Identification Life Technologies 5791 VAN ALLEN WAY PO BOX 6482 CARLSBAD, CA 92008 +1 760 603 7200 INVITROGEN CORPORATION NEW ZEALAND LIMITED 18-24 BOTHA ROAD PENROSE AUCKLAND 1006 NEW ZEALAND +011 64 9 579 3024 0800 636 327 INVITROGEN AUSTRALIA PTY LIMITED 30-32 COMPARK CIRCUIT MULGRAVE VIC 3170 AUSTRALIA +011 61 03 9262 3700 1800 636 327 Silver Tower-Beijing Office Room 1711 Beijing Silver Tower #2 DongSanHuan North Rd, Beijing 100027 P.R.China Tel: +86-010-8446 1800 Fax: +86-010-6410 6617 Guangzhou Office Room1010-1013 South Tower Guangzhou World Trade Center Complex 371-376 HuanShi Dong Rd Guangzhou 510095, China Tel: +86-020-8760 9229 Hotline: 800 830 2001 Fax: +86-020-8775 0687 24 hour Emergency Response: 866-536-0631 301-431-8585 Outside of the U.S. ++1-301-431-8585 For research use only. Not intended for human or animal diagnostic or therapeutic uses. Page 1 / 6

Australian MSDS Statement 2. Hazards identification Classified as non-hazardous according to the criteria of Worksafe Australia. GHS - Classification Signal word not hazardous Health hazard not hazardous Physical hazards not hazardous European Union EU Specific Hazard Statements R-phrase(s) S-phrase(s) Principle Routes of Exposure/ Potential Health effects Eyes Skin Inhalation Ingestion Specific effects Carcinogenic effects Mutagenic effects Reproductive toxicity Sensitisation Target Organ Effects May cause eye irritation with susceptible persons. May cause skin irritation in susceptible persons. May be harmful by inhalation. May be harmful if swallowed. No known effects under normal use conditions Page 2 / 6

3. COMPOSITION/INFORMATION ON INGREDIENTS The product contains no substances which at their given concentration, are considered to be hazardous to health. We recommend handling all chemicals with caution. 4. FIRST AID MEASURES Skin contact Eye contact Ingestion Inhalation Notes to physician Rinse with plenty of water. If symptoms arise, call a physician. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. If symptoms persist, call a physician. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician. Do not induce vomiting without medical advice. Move to fresh air. If symptoms persist, call a physician. If not breathing, give artificial respiration. Treat symptomatically. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Special protective equipment for firefighters Water spray. Carbon dioxide (CO2). Foam. Dry chemical. Wear self-contained breathing apparatus and protective suit. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Methods for cleaning up Use personal protective equipment. Soak up with inert absorbent material. Environmental precautions Prevent further leakage or spillage if safe to do so. See Section 12 for additional information. 7. HANDLING AND STORAGE Handling Storage Avoid contact with skin, eyes and clothing. Wear personal protective equipment. Keep in a dry, cool and well-ventilated place. 8. Exposure controls/personal protection Exposure limits We are not aware of any national exposure limit. Engineering measures Ensure adequate ventilation, especially in confined areas. Page 3 / 6

Personal protective equipment Personal Protective Equipment requirements are dependent on the user institution's risk assessment and are specific to the risk assessment for each laboratory where this material may be used. Respiratory protection In case of insufficient ventilation wear suitable respiratory equipment. Hand protection Eye protection Skin and body protection Hygiene measures Environmental exposure controls Impervious gloves. Safety glasses with side-shields. Lightweight protective clothing. Handle in accordance with good industrial hygiene and safety practice. Prevent product from entering drains. 9. PHYSICAL AND CHEMICAL PROPERTIES General Information Form Appearance Odour Boiling Point/Range Melting point/range Flash point Autoignition temperature oxidising properties Water solubility liquid No information available No information available No information available soluble 10. STABILITY AND REACTIVITY Stability Materials to avoid Hazardous decomposition products polymerisation Stable under normal conditions. No dangerous reaction known under conditions of normal use. under normal use. Hazardous polymerisation does not occur. Page 4 / 6

11. Toxicological information Acute toxicity Not hazardous Principle Routes of Exposure/ Potential Health effects Eyes Skin Inhalation Ingestion Carcinogenic effects Mutagenic effects Reproductive toxicity Sensitisation Target Organ Effects May cause eye irritation with susceptible persons. May cause skin irritation in susceptible persons. May be harmful by inhalation. May be harmful if swallowed..... No known effects under normal use conditions 12. ECOLOGICAL INFORMATION Ecotoxicity effects Mobility Biodegradation Bioaccumulation No information available. No information available. Inherently biodegradable. Does not bioaccumulate. Dispose of in accordance with local regulations. 13. DISPOSAL CONSIDERATIONS 14. TRANSPORT INFORMATION IATA Proper shipping name Hazard class Subsidiary Class Packing group UN-No Not classified as dangerous in the meaning of transport regulations. Page 5 / 6

15. Regulatory information International Inventories International Inventories Complies Industrial Safety and Health Law This product complies with ISHL Toxic Chemicals Control Law Korea Complies 16. OTHER INFORMATION Reason for Revision (M)SDS sections updated For research use only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unkown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE. End of Safety Data Sheet Page 6 / 6