Formulating With Whey In A Fully Transparent Market Chris Lockwood, PhD President May 22-23, 2018
Driving Protein Demand Only Major Nutrient That Stimulates Muscle Building (Muscle Protein Synthesis, or MPS) Increased Calorie-Burning (Thermogenic) vs CHO or FAT Reduces Hunger More than CHO or FAT Increases Body Fat and Weight Loss, and Reduces Negative Effects on Lean Body Mass when Combined w/ a Calorie-Restricted Diet Reduces Age- or Inactivity-induced Muscle and Strength Loss Improves Insulin Sensitivity and Blood Glucose Control Supports Healthy Blood Pressure and Inflammatory Response Critical for a Robust Immune System Westerterp-Plantenga MS et al. 2012; Leidy HJ 2014; Clifton PM et al. 2014; Petzke KJ et al. 2014; Margolis LM and Pasiakos SM. 2013; Guadagni M and Biolo G. 2009; Teunissen-Beekman KF and van Baak MA. 2013; McLean RR et al. 2014.
Why Whey? WHEY EGG CASEIN MEAT SOY PROTEIN ALGAE PEA HEMP RICE OTHER PLANT
Whey Most Effective Protein Source for Stimulating MPS Fast(est) Protein Increases Essential (EAA), Branched-Chain Amino Acid (BCAA), and Bioactive Peptide Rate of Appearance in Blood Powerful Antioxidant Support Increases Glutathione Reduces Inflammation and Cortisol Response / Improves Recovery from Physiological Stress Increases Non-Glucose Insulin Release Improves Exercise Recovery Anabolism, Increases Blood Flow, Reduces Muscle Breakdown, Improves Glucose Metabolism and More Morifuji M et al. 2010; Ha E and Zemel MB. 2003; Katsanos CS et al. 2008; Beelen M et al. 2008; Dangin M et al. 2002; Krissansen GW. 2007; Calbet JA and Holst JJ. 2004; Lockwood CM et al. 2017; Hulmi JJ et al. 2010; Devries MC and Phillips SM. 2015; Miller PE et al. 2014; Moore DR et al. 2009.
Survive -v- Thrive Milk Protein Isolate ( SMP ) Preferentially Increases Protein Synthesis Efficiency in Skeletal Muscle ( P area ) Soy Protein Isolate ( SSP ) Preferential to Non-Skeletal Muscle ( S bed ) & Increases Nitrogen Excretion / Loss Fouillet H et al. J Nutr 2002;132:125-33.
Fast Effects via Fast Protein? At Rest: Whey +93% > Casein Whey +18% > Soy After Exercise: Whey +122% > Casein Whey +31% > Soy Tang JE et al. J Appl Physiol 2009;107:987-92.
Just the EAAs or Leucine? Mobley et al. J Dairy Sci 2017;100(1):48-64
Protein Type I Adaptation Potential Training Type II Adaptation Potential Whey Skeletal Muscle Adaptation Potential Whey 2x MORE Effective Than Soy @ Increasing Skeletal Muscle Resistance Training Adaptation Mobley et al. Nutrients 2017;9:972
Testosterone, Not Leucine? RODENTS HUMANS Mumford et al. [In Review] 54 mg Leu Post-Ex 50 mg Leu Post-Ex WPC = +33.3% Increase in Circulating Testosterone Mobley et al. [in Review]
Anabolic : Catabolic Whey Post-Exercise Testosterone Whey Post-Exercise Cortisol Kraemer WJ et al. J Am Coll Nutr 2013;32(1):66-74
Does Protein Form Matter? Any Whey Muscle Mass Extensive WPH Fat Loss Lockwood CM et al. J Amer Coll Nutr 2017;36(1):16-27
Moderate WPH (~12 DH) vs WPC FAT & CHO Metabolism PRO Catabolism @ 30-60 min Post-Prandial Roberts MD et al. Appl Physiol Nutr Metab 2014;39:158-67.
Form & Source Specificity Hydrolysates Acute Anabolism Protein Source Affects Metabolism Morifuji M et al. J Agric Food Chem 2010;58:8788-97
But Plant Protein Pandemonium Whey IS Vegetarian Whey IS Sustainable / Renewable Whey CAN BE Certified Non-GMO Whey CAN BE Certified Organic Whey IS Gluten Free Whey IS Easy to Flavor* Whey IS Easy to Digest Whey IS Low Allergen* Whey IS A Complete, High Quality Protein And, Whey IS The Human Body s First Protein
No Other Protein Is More Natural LACTATION PERIOD WHEY (%) CASEIN (%) Early 90 10 Mature 60 40 Late 50 50 No Vegan Moms Do NOT Produce Vegan Milk Liao Y et al. J Proteome Res 2017;16(11):4113-21; Kunz C and Lonnerdal B. Acta Paediatr 1992;81(2):107-12
Win, The Full Transparency Whey Invest In Experimental & Finished Product Research Publish Analytical Testing Nutritionals Amino Acid Profiles M.W. Profiles Contaminants (e.g., Pesticide Residues, HMs) Full Disclosure Labeling of Protein Blends Social Warrior Marketing 3 rd Party Validation Certs & Seals Animal Husbandry / Happy Cows Story Telling
Cut A New Path, But Don t Plant Landmines
Which Whey?
Formula Recommendations Size Strength Performance WPC WPI Low DH WPH (< 10%) (from WPC) (from WPC) (from WPC) Mod DH WPH (10%-25%) High DH WPH (> 25%) Weight Body Fat Aging Effects Clinical Health Keto Diet / (from WPI) (from WPI) Carb Restricted Lactose Avoidance (from WPI) (from WPI) (from WPI) (from WPI) Low Allergenicity Affordable Pricepoint Fashion Over Function (i.e., Taste & Speed to Market Priority)
Thank You Chris Lockwood, PhD, CSCS 805-279-3581 (phone) Chris@DrChrisLockwood.com