Welcome to LEWA Process Technologies, Inc.
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1 Welcome to LEWA Process Technologies, Inc. LEWA Center Of Excellence for High Purity Devens, MA LEWA Process Technologies; LEWA PT Business Overview.. Version 2015 Rev. 7
2 Agenda Corporate Structure Main Groups: Nikkiso LEWA LEWA PT LEWA Group Global Look at LEWA Products LEWA Process Technologies, Inc. Clean Market Example Systems Produced by LPT Example Systems Produced by LEWA GmbH for Clean Market LEWA Process Technologies; Introduction to our company Version 2015 Rev. 7 2
3 Nikkiso Factsheet NIKKISO CO., LTD. Executive Management Headquarters Date of Establishment Registered Capital Net Sales (cons.) March 2013 No. of employees Stock Exchange Listing Core business Toshihiko Kai, President & CEO Yebisu Garden Place Tower Tokyo , Japan December 26, ,544 million yen 104,000 million yen (consolidated) 5,411 (consolidated) First Section of Tokyo Stock Exchange 80,286,464 issued shares Industrial Division Aerospace Division Precision Equipment Medical Division LEWA GmbH 1/7/2015 3
4 LEWA-Nikkiso Industrial Division (pumps + systems) Factsheet LEWA-Nikkiso Industrial Division Original Manufacturers, system integrators, sales / service engineers Executive Management Headquarters Naota Shikano (CEO), Dr.-Ing. Martin Fiedler (COO) Stefan Glasmeyer (CMO) LEWA GmbH, Leonberg / Germany Places affiliates Net Sales (cons.) March/2013 Thereof LEWA USD 280 m Add. LPT USD 10 m LEWA Geveke IPT >> LEWA Process Technologies affiliates Nikkiso No. of employees Core business 2,088 in total 560 in Germany of LEWA 520 in Japan of NIKKISO 768 Intl. of LEWA & NIKKISO 75 LEWA Process Technologies Chromatography Systems Reciprocating pumps Canned motor pumps Cryogenic pumps Metering & conditioning systems Services LEWA GmbH 1/7/2015 4
5 LEWA-Nikkiso Business Core Business Strategic Business Oil & Gas Upstream Process Industry & Downstream LNG supply chain markets Utilities Clean Markets Package Diversification Reciprocating Pumps Systems & Packages Canned Motor Pumps Cryogenic Pumps Partner Products Services & Aftersales LEWA GmbH. 1/7/2015 5
6 LEWA-Nikkiso Industrial Division Overview Customer Solutions Various Applications of Original Manufacturers, system integrators, sales / service engineers affiliates Pharmaceutical Personal Care Food Beverages Oil & Gas Products Chemicals Petrochemicals Plastics Cleaning Nikkiso Non- Seal Pump Geveke N2 generation LEWA ecoflow Nikkiso Cryogenic Detergents Energy LEWA diaphragm process pump Water Treatment Exclusive rights in many regions for Partner Products EcoPrime LPLC Environment Other Industries LEWA GmbH 1/7/2015 6
7 LEWA Process Technologies Factsheet (Former Integrated Process Technologies) LEWA Process Technologies, Inc. Executive Management Headquarters in Date of Establishment Ownership Net Sales (cons.) 2013 No. of employees Target markets Jim Banks (CEO) Christopher Sandusky (CTO) Gerard Gach (CMO) US Devens, MA % subsidiary of LEWA- Nikkiso America, Inc. EUR 7.6 m ($10.4 m) 75 Bio / pharmaceutical Personal Care Fine Chemical Core business Systems engineering and services integrating Process expertise Fabrication Automation Installation Services LEWA Process Technologies, Inc. 1/7/2015 7
8 Agenda LEWA Group Corporate Structure Main Groups: Nikkiso LEWA LEWA PT LEWA Group A Global Look at LEWA Products LEWA Process Technologies Clean Market Example Systems Produced by LPT Example Systems Produced by LEWA GmbH for Clean Market LEWA Process Technologies; Introduction to our company Version 2015 Rev. 7 8
9 LEWA Milestones from Family Business to International Group Company Foundation First ACHEMA G4T biggest process diaphragm pump Integration LEWA- Nikkiso Record Project USD 40 m Acquisition of Integrated Process Technologies, Inc Integrated Process Technologies, Inc. Founded 2000 First Patent LEWA ecoflow DBAG and Quadriga Capital acuire LEWA Strategic Business Diversification in Clean Markets New Management for Strategy LEWA Process Technologies, Inc. 1/7/2015 9
10 LEWA; System Integrator and Engineering Services LEWA Systems LEWA-Nikkiso acts as a system integrator and global packager for Industrial and Clean Markets LEWA Process Technologies acts as a system integrator and engineering services specializing in the Life Sciences and Regulated Industries globally leveraging LEWA- Nikkiso companies We combine mechanical engineering, fluid dynamics, electrical control, large-scale fabrication, and project management know-how. 1/7/ LEWA Process Technologies, Inc.
11 LEWA Systems Capability LEWA Process Technologies Products Chemical Injection Package LEWA EcoPrime LEWA odorizing system LEWA ecofoam Customer specific packages for chemical injection in the oil and gas industry Chromatography system with innovative, mechatronic drive and hygienic diaphragm metering pumps LEWA has built odorizing systems for over 40 years, e.g., for natural gas, oxygen, nitrogen and carbon dioxide System for metering various blowing agents in plastic manufacture in combination with extruders LEWA production unit Nitrogen Generation Buffer Inline Dilution OEM Systems Customer specific batch/continuous systems for production processes LEWA Process Technologies, Inc. Industry-scale, custom-designed membrane-type package with very low lifecycle costs System to mix all ingoing fluids, e.g. prior to a chromatography system LEWA Process Technologies Products Systems designed and fabricated for OEM clients in Clean Process Industry LEWA Process Technologies Products 1/7/
12 LEWA Group: Industrial Division Order Bookings Split 2013 by Industry in % Power Plants & Nuclear 5 Plastic, Ceramic, Textiles 11 Clean Markets* 10 Others 6 Oil & Gas 39 Refinery, Petrochemicals, Chemicals 32 LEWA Process Technologies, Inc. 1/7/ * Does not reflect full Clean Market supply; OEM business not fully recognized.
13 LEWA Group Vision: No. 1 in Creating Fluid Solutions Number 1 in Creating Fluid Solutions for all customers in our target markets. Creating......Fluid......Solutions Creating suits the brand personality of LEWA as an ambitious maker and creative manufacturer, who goes beyond (technological) boundaries. Fluid designates the core business. LEWA doses, injects, conveys, mixes, fills, separates and heats or cools liquids and knows how to handle critical fluids in all states as well as their interactions with materials. We understand customer s processes and identify their respective pain points. Therefore we offer complete systems backed by highquality life-cycle services. LEWA GmbH 1/7/
14 LEWA: Focus on own Research & Development Structured Innovation Management Internal R&D department works independently of our daily business Structured process for innovation management in place Various patents in place Knowledge network with universities Test stand - process pumps: max. ca. 350kW hydraulic power Latest software tools in use CAD solid edge Electrical design Finite element analysis (FEM): ANSYS Computational fluid dynamics (CFD): CFX Computer aided measurement LEWA GmbH 1/7/
15 LEWA Group Hub Subsidiaries LEWA China Sales Engineering Pump production Fabrication LEWA Process Technologies Engineering Fabrication LEWA GmbH Headquarters Industrial Division Sales Engineering Pump production Fabrication LEWA-Nikkiso America, Inc. Sales Engineering Fabrication LEWA Bombas, Brazil Sales Engineering Fabrication Geveke Sales Engineering Fabrication LEWA S.R.L. Sales Engineering Fabrication LEWA Middle East FZE Sales Engineering Fabrication LEWA PTE LTD Sales Engineering Fabrication Nikkiso Co., Ltd. Group Headquarters Nikkiso Pumps Korea Ltd. Sales LEWA GmbH 1/7/
16 LEWA Group Service Worldwide Service Portfolio Customer service Repairs Commissioning of equipment Health checks Spare parts Fast and worldwide Maintenance contracts Revamping of entire systems Fluid evaluation Internal and external seminars for users LEWA GmbH 1/7/
17 Certificates, Memberships, Standards within LEWA Corporation Member of VDMA e.v. (Association of German Machine and Plant Engineering) Member of the Hydraulic Institute GOST-R Export-certificate for Russia Certified according to DIN EN ISO 9001 TÜV SÜD Member of the VDMA e-market Member of network of competence process engineering Pro3 e.v. Member of DIN e.v. (German Institute for Standardization) Partner of the Engineering Industry Sustainability Initiative Member of ISPE International Society for Pharmaceutical Engineering Pumps according to guidelines of the European Hygienic Engineering & Design Group Pumps according to guidelines: API 674 and API 675 Member of Cleaning Excellence Center Member of the Europump Organization Material according to U.S. Food and Drug Administration Registered at FPAL First Point Assessment LEWA GmbH 1/7/
18 Agenda LEWA Process Technologies, Inc. Corporate Structure Main Groups: Nikkiso LEWA LEWA PT LEWA Group Global Look at LEWA Products LEWA Process Technologies Clean Market Example Systems Produced by LPT Example Systems Produced by LEWA GmbH for Clean Market LEWA Process Technologies; Introduction to our company Version 2015 Rev. 7 18
19 IPT More information at LPT New name, New brand, New website September 2014
20 The Product Structure of LEWA Process Technologies, Inc. Our Offerings Professional Services / Design Build Engineering LPLC, HPLC Chromatography Systems Batch to Continuous Processing Systems OEM & Custom Engineered Products Automation Field Piping & Installation LEWA Process Technologies, Inc. - Products & Services LEWA Process Technologies, Inc. 1/7/
21 Example of our work: Purification Systems LEWA EcoPrime LPLC Custom-designed chromatography system Pressure: 0.04 l/min up to 33.1 l/min (EcoPrime 500) Flow rate: up to 10 bar Precise flow rate with minimum pulsation Dynamic flow range 1:150 Low holdup volume 0.5 to 99.5% step and linear gradient capability Low shear to process biomolecules Target markets: pharmaceutical and biopharmaceutical LEWA GmbH 1/7/
22 LEWA Process Technologies, Inc. Our Purpose To become the world s leading innovator of systems that reinvent the downstream processing of critical fluids. Processing Brilliance. We are: Innovative Reproducible End-to-end Flexible Nimble Accurate Precise Experienced Processing Brilliance Our Value Proposition LEWA Process Technologies is the only company that combines deep expertise in fluid dynamics with proven pump technology to engineer advanced systems that move fluids with unmatched precision, reproducibility, flexibility and efficiency. We work with you to provide them with the industry s most advanced and well-engineered fluid processing platforms so they can create products with unmatched precision and efficiency.
23 Customer Base & Industry Requirements Representative List of Customer Base What LEWA Delivers Software with ease of validation. High metering accuracy (recipe consistency) Good repeatability (HACCP) High reliability Gentle to the product Good cleanability to ensure food safety, CIP, SIP Use of approved material and lubricants (FDA, NSF) Hygienic pump selection for critical application (EHEDG) LEWA Process Technologies CONFIDENTIAL Use of logo or name does not imply endorsement. Logo s are property of respective companies. 1/7/
24 Work Flow For LEWA Process Technologies - our Strength, Your Benefit LPT maintains a full compliment of departments that ensure the project has the right resources A clear differentiator from other suppliers. Constant Customer Interface Manufacturing / Fabrication Complete array of expertise to ensure comprehensive management of the design Process experts at each step. Project Mangement Subject Matter Experts 4 Field Installation / Service 3 QA/QC 2 Automation Engineering 1 Mechanical/Design/CAD Engineering Process Engineering LEWA Process Technologies, Inc. 1/7/
25 On Spec. On Budget. On Time. The Well Defined Project Work Flow at LEWA Process Technologies Assures a Quality End Product. LEWA Process Technologies, Inc. Confidential - Non Controlled Copy Full workflow charts available for review within on site audit meetings
26 Application Development Laboratory In addition to a well equipped FAT (Factory Acceptance Test) area, LEWA Process Technologies has dedicated space and resources to characterize our products for the intended application. LEWA Process Technologies, Inc. 1/7/
27 Custom Specialists. Getting you what you want LEWA Process Technologies understands the best system is designed to your standard. We are experts in custom design systems. LEWA GmbH 1/7/
28 Engineering Services. LEWA Process Technologies is long known for unique insights into high purity processes. A comprehensive staff of process engineers, project manages, automation engineers, world class fabrication and on site installation sets LEWA Process Technologies apart from others. LEWA Process Technologies, Inc. 1/7/
29 Downstream Expertise. LEWA Process Technologies understands downstream and creates value through reduction in footprint, batch to batch reproducibility and precision that results in yield improvement. Ingenuity with process integrity is our commitment. LEWA Process Technologies, Inc. 1/7/
30 Agenda Corporate Structure Main Groups: Nikkiso LEWA LEWA PT LEWA Group Global Look at LEWA Products LEWA Process Technologies Clean Market Example Systems Produced by LPT Example Systems Produced by LEWA GmbH for Clean Market LEWA Process Technologies; Introduction to our company Version 2015 Rev. 7 30
31 Application Example: Continuous Processing Location USA (Biopharma Process Development facilities). Delivered 2014 Application Multiple purification processes linked to performed continuous processing of protein based therapies under development. LEWA solution LEWA Process Technologies original design in concert with major biopharmaceutical company. LPT automation, system design and manufacture. LEWA Process Technologies, Inc. 1/7/
32 Application Example: Chromatography Systems Location Asia Delivered 2014 Application Low Pressure Chromatography skids for monoclonal antibody production for GMP production. LEWA solution LEWA original design in concert with major biopharmaceutical company. Employed LEWA Intellidrive EcoDos pumps with system design and manufacture by LPT. LEWA Process Technologies, Inc. - Confidential 1/7/
33 Application Example: Ultrafiltration Processing System Location EU, USA, Asia (Multiple Biopharma Facilities). Delivered series of units starting 2008 Application Hollow Fiber Membrane production skid for GMP production. LEWA solution LEWA OEM design for major life sciences technology supply company. LEWA Process Technologies design and manufacture based on OEM supplied concept. LEWA Process Technologies, Inc. - Confidential 1/7/
34 Application Example: Membrane Purification System Location USA (Biopharma Facilitiy). Delivered 2011 Application Hollow Fiber Membrane production skid for GMP production. LEWA solution LEWA original design for major biopharmaceutical company. Employed LEWA EcoDos pumps with system design and manufacture by LPT. LEWA Process Technologies, Inc. - Confidential 1/7/
35 Application Example: Centrifuge System Location USA (Biopharma Facilitiy). Delivered 2014 Application Clarification of biologic in a GMP production plant. LEWA solution OEM centrifuge complimented by LEWA design and manufacture for a biopharmaceutical company. Employed LEWA pumps. LEWA Process Technologies, Inc. - Confidential 1/7/
36 Application Example: Portable Filling Station Location USA (Pharma Production facilities), multiple units delivered since 2011 Application Filling intermediate and bulk liquid drug substances from 0.2 to 5.0L in microbial controlled semi automated portable station with built in weighing. LEWA solution LEWA Process Technologies original design in concert with major biopharmaceutical company. LEWA Process Technologies, Inc. 1/7/
37 Application Example: Buffer Dilution System Location USA (GMP Bio/pharma Facility). Delivered 2009 Application Buffer preparation for pharmaceutical manufacturing processing LEWA solution LEWA Process Technologies design and manufacture purpose built to meet A&E design. Manufactured, FAT and disassembled for shipping and re-assembly on customer site. LEWA Process Technologies, Inc. - Confidential 1/7/
38 Application Example: Beverage Processing LEWA solution LEWA Process Technologies design and manufacture purpose built to meet customer design. Fabricated in a mobile container for shipping and plug and play operation at the customer site. ~60 ft (19 m) ~10 ft (3 m) Location Installation in USA in 2014 Manufactured in USA at LPT in 2014 Application Proprietary processing of consumable product. LEWA Process Technologies, Inc. - Confidential 1/7/
39 Application Example: Control Systems Location USA, EU, Asia (GMP Bio/pharma Facility). Delivered Regularly Application Control of pharmaceutical manufacturing processing, F&B systems, electronics manufacturing skids LEWA solution LEWA Process Technologies designs and manufactures control systems / panels to meet most any system design such at ATEX, CE, ExP. LEWA Process Technologies, Inc. - Confidential 1/7/
40 Agenda Corporate Structure Main Groups: Nikkiso LEWA LEWA PT LEWA Group Global Look at LEWA Products LEWA Process Technologies Clean Market Example Systems Produced by LPT Example Systems Produced by LEWA GmbH for Clean" Market LEWA Process Technologies; Introduction to our company Version 2015 Rev. 7 40
41 Application Example: Production of Powder Location Germany (R&D facilities), delivered in 2006 Application Production of powder by spray drying system with hot food or plastic melts, supercritical CO2 160 l/h, bar LEWA solution Temperature controlled pumps, LEWA ecoflow LDE3 LEWA GmbH 1/7/
42 Application Example: Production of aromatized water Location France, delivered in 2007 Application Dosing of aroma for the production of aromatized water bar LEWA solution LEWA ecodos metering pump Mass flow meter and pressure gauge SPS-controlled dosing system LEWA GmbH 1/7/
43 Application Example: Continuous Blending Location Germany, delivered in 2001 Application Continuous blending of gelatine, aroma, colorant and citric acid bar LEWA solution LEWA plunger pump Vessels Mass flow meters Electrical control LEWA GmbH 1/7/
44 Application Example: Liquid Metering for Pharma Extruder Location Germany, Puerto Rico, USA, delivered in 2006, 2007 Application Liquid metering for pharma extruder application LEWA solution Complete system with impeller type mixer, control system, LEWA ecoflow LDB Designed according all qualification and validation steps (cgmp, GAMP) LEWA GmbH, LEWA, v1.0 1/7/
45 Application Example: Production of Buffer for Protein Purification Location Germany, delivered 2008 Application Production of buffer and protein solution, water for injection l/h, 60 2,100 6 bar LEWA solution Entire system, LEWA ecodos hygienic with multiplex heads, frequency converter, multiphase motor and control system LEWA GmbH, LEWA v1.0 1/7/
46 LEWA Process Technologies, Inc. benefits: Global strength, financial security of LEWA-Nikkiso History of ingenuity and execution in GMP environments Full service design engineering fabrication installation; not just a supplier or A&E but a single point vertical supplier from concept to on-site implementation Automation, Process Engineering, Mechanical Design, Fabrication all under one roof assures commercial and technical project certainty Our customer auditing successes illustrate an environment of attention to quality and an environment in tune with GMP customer expectations Your partner of choice for programs that demand high precision, reliable performance using the best in class engineering experience and practice 1/7/
47 Thank you! Visit for more information on LEWA Process Technologies, Inc. Join us on LEWA Process Technologies; Introduction to our company Version 2015 Rev. 7
48 Addenda Slides The following slides may enhance your understanding of LEWA Process Technologies. These are supplied for additional information. LEWA Process Technologies; Introduction to our company Version 2015 Rev. 7 48
49 Mission LEWA Process Technologies Processing Brilliance LEWA Process Technologies draws on its deep expertise in fluid dynamics to conceive, construct and install advanced downstream processing platforms. Our solutions combine years of research in manipulating the movement of critical fluids with proven pump technology to deliver systems with unmatched precision, reproducibility, flexibility and efficiency. We help customers in clean industries such as biotechnology and pharmaceuticals gain competitive advantage by giving them tools to create the next generation of breakthrough products. More at LEWA Process Technologies, Inc. 1/7/
50 Reliable and Safe. Consistent and Precise. LEWA Process Technologies systems do not compromise on process integrity. We employ our leading sanitary and hygienic pumps known for exceptional precision and long life with low maintenance. Ingenuity coupled with leading pump technology. That is the no compromise promise from LEWA Process Technologies. LEWA GmbH 1/7/
51 Flow Purity. System Integrity. LEWA Process Technologies systems are centered on leading sanitary and hygienic pumps known for exceptional precision and long life with low maintenance. Ingenuity coupled with leading pump technology. That sets LEWA Process Technologies apart from others. LEWA GmbH 1/7/
52 Precise. Repeatable. Formulation Consistency Making your process repeatable and the quality spot on batch to batch is a strength of LEWA. We employ our leading sanitary and hygienic pumps known for exceptional precision and our automation package simplifies control and quality documentation. Ingenuity coupled with leading pump & dispensing technology. That is the no compromise promise from LEWA. LEWA GmbH 1/7/
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