Bio-Optica Milano S.p.a. Malachite green solution

Transcription

1 SECTION Hazards Exposure Regulatory Or Toxicological identification. controls/personal... /... >> /... >> protection. /... >> / >>... / >> Page n / 07 Safety data sheet 2.3. GERAL LD50 Use Or (Oral). protective hazards. BIBLIOGRAPHY airtight goggles (ref. standard 166) 275 recommended. mg/kg 1. VIRONMTAL Directive 1999/45/EC EXPOSURE and following CONTROLS. amendments The emissions generated by manufacturing processes, including those generated by ventilation equipment, should be checked to ensure SECTION Substances 2. Information Directive subject 67/548/EEC 6. Accidental to and Stockholm following release Convention: amendments measures. and adjustments SECTION 6.1. SECTION 3. compliance Personal Regulation 12. precautions, 1. with (EC) Identification environmental Ecological 1907/2006 protective (REACH) standards. equipment substance/mixture European and emergency Parliament procedures. and company/undertaking 4. SECTION FOR Regulation LIQUID 3. PRODUCTS: (EC) 1272/2008 (CLP) European Parliament 1.1. Healthcare 5. Product controls. Composition/information on ingredients. SECTION sewers Block Regulation identifier or leakage contaminate (EC) 9. Physical if 790/2009 re soil is or no (I and vegetation. Atp. hazard. CLP) European Parliament chemical properties. Use this product according to good working practices. Avoid littering. Inform competent authorities, should product reach waterways or Information This FOR Substances. Regulation product SOLID PRODUCTS: is (EC) dangerous 453/2010 for environment European Parliament and aquatic organisms. In long term, it have negative effects on aquatic environment Code: If Information re Regulation are no (EC) contraindications, basic 286/2011 physical (II Atp. spray and CLP) chemical powder with European B07011, properties. water to Parliament M07011, 07011/L prevent formation dust. Avoid breathing vapours/mists/gases Product Contains: Appearance Wear The Chemical Toxicity. suitable Merck namesafety Index. assessment. protective - 10th Edition equipment (including personal liquid protective equipment referred to under Section 8 safety data sheet) to prevent 9. EC any Colour Handling number contamination Chemical Safety skin, eyes and personal clothing. green These indications apply for both processing staff and those involved in emergency 10. No CAS chemical procedures. Identification. Odour Verde Niosh number Malachite - Registry safety assessment Toxic Conc. Effects has %. been Chemical processed Classification Substances for mixture and substances it contains. odourless 67/548/EEC. Classification 1272/2008 (CLP). 11. Odour LC50 INRS (96h) threshold. - Fiche - for Fish. Toxicologique (toxicological sheet) Not 0,14 mg/l Relevant Verde ph. EC50 Environmental Patty (48h) Malachite - Industrial identified - for Algae precautions. Hygiene uses / Aquatic and Plants. Toxicology substance or mixture and uses advised against SECTION 16. Or Not 0,29 mg/l Daphnia magna 13. The Melting CAS. N.I. product Sax point must / Dangerous freezing penetrate point. properties 0,4 into Industrial Repr. sewer Cat. system 3 Materials-7, R63, Not Xn or R22, come Xi 1989 R41, into N Edition R50/53 contact with surface water Repr. or 2 H361d, ground Acute water. Tox. 3 H301, Eye Dam. 1 H318, Aquatic Chronic 1 H Text Intended Initial EC. Persistence ECHA boiling hazard use website point. (H) and indications degradability. mentioned in section 2-3 In vitro Not medical-diagnostic sheet: disposable. Reagent for microscopy Boiling Information INDEX. Methods range. -and material for containment and cleaning up Details FOR Flash Repr. point. LIQUID 2 supplier PRODUCTS: Reproductive safety data Collect toxicity, sheet leaked category product 2into a suitable container. Evaluate compatibility container to be used, by Note Note: checking Evaporation Bioaccumulative Acute for Upper users: section Tox. Rate limit is Absorb potential. included Acute into remainder toxicity, range. category with inert 3 Not absorbent material. The Name Eye The FOR Flammability Information full information Dam. 1 SOLID wording PRODUCTS: solids contained and Risk gases Serious (R) in Use and spark-pro eye hazard present damage, (H) sheet mechanical phrases category are Bio-Optica Not is based 1 Milano given equipment on in section our S.p.a. to own 16 collect knowledge sheet. leaked on product date and place last it version. in containers Users must for recovery verify or Full disposal. Lower suitability Aquatic address inflammability If and Chronic re thoroughness 1 Hazardous are limit. no contraindications, provided to information aquatic environment, via use jets Not according San Faustino, water to eliminate to each chronic specific 58toxicity, product use category residues. product. 1 T+ District = Very Toxic(T+), T = Toxic(T), Xn = Harmful(Xn), C = Corrosive(C), Xi = Irritant(Xi), O = Oxidizing(O), E = Explosive(E), F+ = Extremely Flammable(F+), F = Highly Flammable(F), N = Dangerous Make Upper This Aquatic Mobility document and Chronic Country inflammability sure for Environment(N) soil. must 3 leakage limit. be Hazardous site regarded is well as to aired. a guarantee aquatic environment, Check Not incompatibility any specific Milano chronic for product toxicity, container property. category 3 material in section 7. Contaminated material should be disposed Lower The H361d Information in compliance use explosive this limit. with product Suspected provisions is subject damaging set forth to our in point direct unborn Not 13. control; Italia child. refore, users must, under ir own responsibility, comply with current health Upper and H301 safety explosive laws and limit. regulations. Toxic if The swallowed. producer is relieved Tel. from 0039 any 02 liability arising from improper uses Mixtures. H Vapour Provide Reference Results pressure. appointed to PBT or staff and sections. with Causes vpvb adequate serious assessment. training eye on damage. how Fax Not to use chemical products. H410 address competent Very toxic person to aquatic life with long lasting effects. Any Vapour information on personal protection and disposal is given sections 8 and 13. Information H412density responsible relevant. Harmful to aquatic life with long lasting effects. Relative Changes On basis density. to for previous Safety available review: Data Sheet info@bio-stain.it data, product does Not contain any PBT or vpvb in percentage greater than 0,1%. Solubility The following sections were modified: soluble in water SECTION Product Text risk (R) phrases mentioned in section 2-3 sheet: Partition 02 Or / 04 / distribution 06 coefficient: adverse / First Handling / 08 by effects. n-octanol/water / 11 / 12 / aid measures. and 15 / 16. storage Auto-ignition 4.1. Precautions R22 temperature. Description for safe handling. HARMFUL IF SWALLOWED Emergency telephone first aid number measures. Before Decomposition Information R41 handling temperature. product, RISK OF consult SERIOUS all DAMAGE or TO sections EYES. this material safety data sheet. Avoid leakage product into EYES: Viscosity R50/53 Remove contact lenses, VERY TOXIC if present TO AQUATIC Wash immediately with plenty water for at least minutes, opening eyelids fully. Get medical environment. advice/attention. Do eat, drink or smoke during Not ORGANISMS, use. MAY CAUSE LONG-TERM ADVERSE EFFECTS IN THE AQUATIC For urgent inquiries refer to Please Remove contact any nearest contaminated Tossicology clos and Antivenin personal protective Center equipment before entering Explosive places in which properties VIRONMT. people eat. SECTION SKIN: Oxidising R52/53 Remove properties 13. contaminated Disposal HARMFUL clothing. considerations. TO Rinse AQUATIC skin with Not ORGANISMS, a shower immediately. MAY CAUSE Get LONG-TERM medical advice/attention. ADVERSE EFFECTS IN THE AQUATIC 9.2. INGESTION: Have subject drink as much water as possible. Get medical advice/attention. Do induce vomiting unless explicitly SECTION Or Conditions Waste treatment 2. for Hazards VIRONMT. safe methods. storage, identification. including any incompatibilities. authorised VOC R63 by a doctor. Store (Directive only in 1999/13/EC) POSSIBLE original container. : RISK OF HARM Store containers 0 TO THE UNBORN CHILD. Reuse, when possible. Product residues should be considered sealed, special in a well hazardous ventilated waste. place, The away hazard from direct level sunlight. waste containing Keep containers this product away 2.1. INHALATION: VOC Classification Get medical advice/attention immediately. Remove victim to fresh air, away from accident scene. If subject stops from any (volatile incompatible carbon) : substance or mixture. should be evaluated according materials, to see applicable section regulations. 10 for details. 0 breathing, administer artificial respiration. Take suitable precautions for rescue workers. Disposal must be performed through an authorised waste management firm, in compliance with national and local regulations. The LEGD: product is classified as hazardous pursuant to provisions set forth in Directives 67/548/EEC and 1999/45/EC and/or EC Regulation 7.3. Specific end use(s) SECTION Avoid littering. Most important 10. Do Stability contaminate symptoms and soil, effects, reactivity. sewers and waterways. 1272/ ADR: European (CLP) Agreement (and subsequent concerning amendments both carriage acute and and Dangerous supplements). delayed. goods The by Road product thus requires a safety datasheet that complies with CONTAMINATED PACKAGING provisions For - CAS symptoms NUMBER: EC and Regulation Chemical effects caused Abstract 1907/2006 by Service and contained subsequent Number substances, amendments. see chap Contaminated Reactivity. packaging must be recovered or disposed in compliance with national waste management regulations. Any - CE50: additional Effective information concentration concerning (required to risks induce for health a 50% and/or effect) environment are given in sections 11 and 12 this sheet. There are no particular risks reaction with or substances in normal conditions use SECTION - CE Indication NUMBER: 8. Exposure any Identifier immediate in ESIS controls/personal medical (European attention archive and existing special protection. substances) treatment needed SECTION - CLP: Regulation Regulation Control Chemical /2008 parameters. stability. Transport 1272/2008 (CLP) and following amendments and adjustments. - DNEL: Derived No Effect Level Information The product is stable in normal conditions use and storage. Hazard The - EmS: product Emergency classification is Schedule and dangerous indication: under current provisions Code International Carriage Dangerous Goods by Road (ADR) and by Rail SECTION -(RID), GHS: Globally 5. Firefighting measures. Aquatic International Chronic Harmonized 3 Maritime H412 System Dangerous classification Goods and Code labeling (IMDG), chemicals and International Air Transport Association (IATA) regulations Exposure Possibility controls. hazardous reactions IATA No Extinguishing DGR: International hazardous reactions media. Air Transport Association Dangerous Goods Regulation are foreseeable in normal conditions use and storage SUITABLE - IC50: 67/548/EEC Immobilization EXTINGUISHING and 1999/45/EC Concentration EQUIPMT Directives 50% and following amendments and adjustments. SECTION As use 15. adequate Regulatory technical equipment must always take priority over personal protection equipment, make sure that workplace is The - IMDG: extinguishing International equipment Maritime should Code for be dangerous conventional goods kind: carbon dioxide, foam, powder and water spray. well Conditions aired UNSUITABLE through to avoid. Danger - IMO: International Symbols: effective local aspiration. EXTINGUISHING Maritime Organization EQUIPMT -- None HAND None in PROTECTION particular. However usual precautions used for chemical products should be respected R - INDEX phrases: Safety, in particular. NUMBER: health and Identifier environmental in Annex 52/53 VI regulations/legislation CLP specific for substance or mixture. - Protect LC50: Lethal hands Concentration with category 50% I (ref. Directive 89/686/EEC and standard 374) work gloves, such as those in latex, PVC or equivalent. The following Incompatible Special should materials. Seveso The - LD50: full category. Lethal wording hazards dose be considered arising 50% Risk from (R) and when hazard choosing substance (H) phrases work or mixture. is glove given in material: section 16 degradation, sheet. breakage times and permeation. Work glove resistance to preparations Information should be checked before use, as it can be unpredictable. Gloves limit depends on duration exposure. HAZARDS - OEL: Occupational CAUSED Exposure BY EXPOSURE Level IN THE EVT OF FIRE 2.2. Restrictions SKIN Do - PBT: Label PROTECTION Persistent brea elements. relating combustion bioaccumulative to product products. or and contained toxic as substances REACH Regulation pursuant to Annex XVII to EC Regulation 1907/2006. Wear Hazardous category decomposition I pressional products. - PEC: Product. Predicted environmental Concentration long-sleeved overalls and safety footwear (ref. Directive 89/686/CEE and standard 344). Wash body with 5.3. soap Information and Advice water - Hazard PEL: Point. Predicted labelling after for firefighters. pursuant exposure removing to 3level EC overalls. Regulation 1272/2008 (CLP) and subsequent amendments and supplements. RESPIRATORY PROTECTION GERAL - PNEC: Predicted INFORMATION no effect concentration SECTION Substances Use - Hazard If REACH: threshold jets pictograms: in value (if available) EC 11. Candidate water Regulation Toxicological List (Art. 59 to cool 1907/2006 containers --REACH). one more substances present in preparation for daily exposure in workplace or to a to prevent product decomposition and development substances potentially hazardous for fraction established by company s prevention and protection service is exceeded, wear a mask with an B or universal filter, class (1, 2 health. - RID: Regulation Always wear concerning full fire prevention international gear. transport Collect extinguishing dangerous goods water by train to prevent it from draining into sewer system. Dispose contaminated According Signal - TLV: 3) Threshold words: which to must currently be chosen available according water Limit used Value for extinction -- data, to this product limit concentration has yet use produced (ref. standard health damages. 141). Anyway, it must be handled carefully according to and remains fire according to applicable regulations. Substances good The use industrial subject respiratory practices. authorisarion tract This protection product (Annex XIV may equipment, REACH). have slight such health as masks effects like on that sensitive indicated people, above, by is inhalation necessary and/or to reduce cutaneous worker absorption exposure and/or in SPECIAL - TLV CEILING: PROTECTIVE Concentration EQUIPMT that should FOR FIRE-FIGHTERS be exceeded during any time occupational exposure. contact Normal Hazard - absence TWA STEL: statements: with technical eyes and/or measures. ingestion. The protection provided by masks is in any case limited. fire fighting Short-term clothing exposure i.e. limit fire kit (BS 469), gloves (BS 659) and boots (HO specification A29 and A30) in combination with If substance in question self-contained - TWA: H412Time-weighted open circuit average Harmful is odourless positive exposure to pressure aquatic limit compressed life or its with olfactory long air lasting threshold breathing effects. is higher than relative exposure limit and in event an emergency, apparatus (BS 137) Substances - Precautionary or VOC: Information when Volatile exposure subject statements: organic on toxicological levels exportation Compounds are unknown reporting effects. pursuant or to concentration (EC) Reg. 689/2008: oxygen in workplace is less than 17% volume, wear self-contained, - open-circuit vpvb: P273Very compressed Persistent and Avoid air very breathing release Bioaccumulative to apparatus environment. as (ref. for REACH standard Regulation. 137) or fresh air hose breathing apparatus for use with full face mask, half Nr. mask EC: or mouthpiece (ref. standard ). Substances Verde EYE PROTECTION Malachite subject to Rotterdam Convention:

2 SECTION 2. Hazards identification.... / >> Page n. 2 / Or hazards. SECTION 3. Composition/information on ingredients Substances. Contains: Identification. Conc. %. Classification 67/548/EEC. Classification 1272/2008 (CLP). Verde Malachite CAS ,4 Repr. Cat. 3 R63, Xn R22, Xi R41, N R50/53 Repr. 2 H361d, Acute Tox. 3 H301, Eye Dam. 1 H318, EC Aquatic Chronic 1 H410 INDEX. - Note: Upper limit is included into range. The full wording Risk (R) and hazard (H) phrases is given in section 16 sheet. T+ = Very Toxic(T+), T = Toxic(T), Xn = Harmful(Xn), C = Corrosive(C), Xi = Irritant(Xi), O = Oxidizing(O), E = Explosive(E), F+ = Extremely Flammable(F+), F = Highly Flammable(F), N = Dangerous for Environment(N) 3.2. Mixtures. Information relevant. SECTION 4. First aid measures Description first aid measures. EYES: Remove contact lenses, if present Wash immediately with plenty water for at least minutes, opening eyelids fully. Get medical advice/attention. SKIN: Remove contaminated clothing. Rinse skin with a shower immediately. Get medical advice/attention. INGESTION: Have subject drink as much water as possible. Get medical advice/attention. Do induce vomiting unless explicitly authorised by a doctor. INHALATION: Get medical advice/attention immediately. Remove victim to fresh air, away from accident scene. If subject stops breathing, administer artificial respiration. Take suitable precautions for rescue workers Most important symptoms and effects, both acute and delayed. For symptoms and effects caused by contained substances, see chap Indication any immediate medical attention and special treatment needed. SECTION 5. Firefighting measures Extinguishing media. SUITABLE EXTINGUISHING EQUIPMT The extinguishing equipment should be conventional kind: carbon dioxide, foam, powder and water spray. UNSUITABLE EXTINGUISHING EQUIPMT None in particular Special hazards arising from substance or mixture. HAZARDS CAUSED BY EXPOSURE IN THE EVT OF FIRE Do brea combustion products Advice for firefighters. GERAL INFORMATION Use jets water to cool containers to prevent product decomposition and development substances potentially hazardous for health. Always wear full fire prevention gear. Collect extinguishing water to prevent it from draining into sewer system. Dispose contaminated water used for extinction and remains fire according to applicable regulations. SPECIAL PROTECTIVE EQUIPMT FOR FIRE-FIGHTERS Normal fire fighting clothing i.e. fire kit (BS 469), gloves (BS 659) and boots (HO specification A29 and A30) in combination with self-contained open circuit positive pressure compressed air breathing apparatus (BS 137).

3 Page n. 3 / 7 SECTION 6. Accidental release measures Personal precautions, protective equipment and emergency procedures. FOR LIQUID PRODUCTS: Block leakage if re is no hazard. FOR SOLID PRODUCTS: If re are no contraindications, spray powder with water to prevent formation dust. Avoid breathing vapours/mists/gases. Wear suitable protective equipment (including personal protective equipment referred to under Section 8 safety data sheet) to prevent any contamination skin, eyes and personal clothing. These indications apply for both processing staff and those involved in emergency procedures Environmental precautions. The product must penetrate into sewer system or come into contact with surface water or ground water Methods and material for containment and cleaning up. FOR LIQUID PRODUCTS: Collect leaked product into a suitable container. Evaluate compatibility container to be used, by checking section 10. Absorb remainder with inert absorbent material. FOR SOLID PRODUCTS: Use spark-pro mechanical equipment to collect leaked product and place it in containers for recovery or disposal. If re are no contraindications, use jets water to eliminate product residues. Make sure leakage site is well aired. Check incompatibility for container material in section 7. Contaminated material should be disposed in compliance with provisions set forth in point Reference to or sections. Any information on personal protection and disposal is given in sections 8 and 13. SECTION 7. Handling and storage Precautions for safe handling. Before handling product, consult all or sections this material safety data sheet. Avoid leakage product into environment. Do eat, drink or smoke during use. Remove any contaminated clos and personal protective equipment before entering places in which people eat Conditions for safe storage, including any incompatibilities. Store only in original container. Store containers sealed, in a well ventilated place, away from direct sunlight. Keep containers away from any incompatible materials, see section 10 for details Specific end use(s). SECTION 8. Exposure controls/personal protection Control parameters Exposure controls. As use adequate technical equipment must always take priority over personal protection equipment, make sure that workplace is well aired through effective local aspiration. HAND PROTECTION Protect hands with category I (ref. Directive 89/686/EEC and standard 374) work gloves, such as those in latex, PVC or equivalent. The following should be considered when choosing work glove material: degradation, breakage times and permeation. Work glove resistance to preparations should be checked before use, as it can be unpredictable. Gloves limit depends on duration exposure. SKIN PROTECTION Wear category I pressional long-sleeved overalls and safety footwear (ref. Directive 89/686/CEE and standard 344). Wash body with soap and water after removing overalls. RESPIRATORY PROTECTION If threshold value (if available) for one or more substances present in preparation for daily exposure in workplace or to a fraction established by company s prevention and protection service is exceeded, wear a mask with an B or universal filter, class (1, 2 or 3) which must be chosen according to limit concentration use (ref. standard 141). The use respiratory tract protection equipment, such as masks like that indicated above, is necessary to reduce worker exposure in absence technical measures. The protection provided by masks is in any case limited. If substance in question is odourless or its olfactory threshold is higher than relative exposure limit and in event an emergency, or when exposure levels are unknown or concentration oxygen in workplace is less than 17% volume, wear self-contained, open-circuit compressed air breathing apparatus (ref. standard 137) or fresh air hose breathing apparatus for use with full face mask, half mask or mouthpiece (ref. standard 138). EYE PROTECTION

4 SECTION 8. Exposure controls/personal protection.... / >> Page n. 4 / 7 Use protective airtight goggles (ref. standard 166) recommended. VIRONMTAL EXPOSURE CONTROLS. The emissions generated by manufacturing processes, including those generated by ventilation equipment, should be checked to ensure compliance with environmental standards. SECTION 9. Physical and chemical properties Information on basic physical and chemical properties. Appearance liquid Colour green Odour odourless Odour threshold. ph. Melting point / freezing point. Initial boiling point. Boiling range. Flash point. Evaporation Rate Flammability solids and gases Lower inflammability limit. Upper inflammability limit. Lower explosive limit. Upper explosive limit. Vapour pressure. Vapour density Relative density. Solubility soluble in water Partition coefficient: n-octanol/water Auto-ignition temperature. Decomposition temperature. Viscosity Explosive properties Oxidising properties 9.2. Or VOC (Directive 1999/13/EC) : 0 VOC (volatile carbon) : 0 SECTION 10. Stability and reactivity Reactivity. There are no particular risks reaction with or substances in normal conditions use Chemical stability. The product is stable in normal conditions use and storage Possibility hazardous reactions. No hazardous reactions are foreseeable in normal conditions use and storage Conditions to avoid. None in particular. However usual precautions used for chemical products should be respected Incompatible materials Hazardous decomposition products. SECTION 11. Toxicological According to currently available data, this product has yet produced health damages. Anyway, it must be handled carefully according to good industrial practices. This product may have slight health effects on sensitive people, by inhalation and/or cutaneous absorption and/or contact with eyes and/or ingestion Information on toxicological effects. Verde Malachite

5 SECTION 11. Toxicological... / >> Page n. 5 / 7 LD50 (Oral). 275 mg/kg SECTION 12. Ecological Use this product according to good working practices. Avoid littering. Inform competent authorities, should product reach waterways or sewers or contaminate soil or vegetation. This product is dangerous for environment and aquatic organisms. In long term, it have negative effects on aquatic environment Toxicity. Verde Malachite LC50 (96h) - for Fish. EC50 (48h) - for Algae / Aquatic Plants. 0,14 mg/l 0,29 mg/l Daphnia magna Persistence and degradability Bioaccumulative potential Mobility in soil Results PBT and vpvb assessment. On basis available data, product does contain any PBT or vpvb in percentage greater than 0,1% Or adverse effects. SECTION 13. Disposal considerations Waste treatment methods. Reuse, when possible. Product residues should be considered special hazardous waste. The hazard level waste containing this product should be evaluated according to applicable regulations. Disposal must be performed through an authorised waste management firm, in compliance with national and local regulations. Avoid littering. Do contaminate soil, sewers and waterways. CONTAMINATED PACKAGING Contaminated packaging must be recovered or disposed in compliance with national waste management regulations. SECTION 14. Transport The product is dangerous under current provisions Code International Carriage Dangerous Goods by Road (ADR) and by Rail (RID), International Maritime Dangerous Goods Code (IMDG), and International Air Transport Association (IATA) regulations. SECTION 15. Regulatory Safety, health and environmental regulations/legislation specific for substance or mixture. Seveso category. Restrictions relating to product or contained substances pursuant to Annex XVII to EC Regulation 1907/2006. Product. Point. 3 Substances in Candidate List (Art. 59 REACH). Substances subject to authorisarion (Annex XIV REACH). Substances subject to exportation reporting pursuant to (EC) Reg. 689/2008: Substances subject to Rotterdam Convention:

6 SECTION 15. Regulatory... / >> Page n. 6 / 7 Substances subject to Stockholm Convention: Healthcare controls Chemical safety assessment. No chemical safety assessment has been processed for mixture and substances it contains. SECTION 16. Or Text hazard (H) indications mentioned in section 2-3 sheet: Repr. 2 Reproductive toxicity, category 2 Acute Tox. 3 Acute toxicity, category 3 Eye Dam. 1 Serious eye damage, category 1 Aquatic Chronic 1 Hazardous to aquatic environment, chronic toxicity, category 1 Aquatic Chronic 3 Hazardous to aquatic environment, chronic toxicity, category 3 H361d Suspected damaging unborn child. H301 Toxic if swallowed. H318 Causes serious eye damage. H410 Very toxic to aquatic life with long lasting effects. H412 Harmful to aquatic life with long lasting effects. Text risk (R) phrases mentioned in section 2-3 sheet: R22 HARMFUL IF SWALLOWED. R41 RISK OF SERIOUS DAMAGE TO EYES. R50/53 VERY TOXIC TO AQUATIC ORGANISMS, MAY CAUSE LONG-TERM ADVERSE EFFECTS IN THE AQUATIC VIRONMT. R52/53 HARMFUL TO AQUATIC ORGANISMS, MAY CAUSE LONG-TERM ADVERSE EFFECTS IN THE AQUATIC VIRONMT. R63 POSSIBLE RISK OF HARM TO THE UNBORN CHILD. LEGD: - ADR: European Agreement concerning carriage Dangerous goods by Road - CAS NUMBER: Chemical Abstract Service Number - CE50: Effective concentration (required to induce a 50% effect) - CE NUMBER: Identifier in ESIS (European archive existing substances) - CLP: EC Regulation 1272/ DNEL: Derived No Effect Level - EmS: Emergency Schedule - GHS: Globally Harmonized System classification and labeling chemicals - IATA DGR: International Air Transport Association Dangerous Goods Regulation - IC50: Immobilization Concentration 50% - IMDG: International Maritime Code for dangerous goods - IMO: International Maritime Organization - INDEX NUMBER: Identifier in Annex VI CLP - LC50: Lethal Concentration 50% - LD50: Lethal dose 50% - OEL: Occupational Exposure Level - PBT: Persistent bioaccumulative and toxic as REACH Regulation - PEC: Predicted environmental Concentration - PEL: Predicted exposure level - PNEC: Predicted no effect concentration - REACH: EC Regulation 1907/ RID: Regulation concerning international transport dangerous goods by train - TLV: Threshold Limit Value - TLV CEILING: Concentration that should be exceeded during any time occupational exposure. - TWA STEL: Short-term exposure limit - TWA: Time-weighted average exposure limit - VOC: Volatile organic Compounds - vpvb: Very Persistent and very Bioaccumulative as for REACH Regulation.

7 SECTION 16. Or... / >> Page n. 7 / 7 GERAL BIBLIOGRAPHY 1. Directive 1999/45/EC and following amendments 2. Directive 67/548/EEC and following amendments and adjustments 3. Regulation (EC) 1907/2006 (REACH) European Parliament 4. Regulation (EC) 1272/2008 (CLP) European Parliament 5. Regulation (EC) 790/2009 (I Atp. CLP) European Parliament 6. Regulation (EC) 453/2010 European Parliament 7. Regulation (EC) 286/2011 (II Atp. CLP) European Parliament 8. The Merck Index. - 10th Edition 9. Handling Chemical Safety 10. Niosh - Registry Toxic Effects Chemical Substances 11. INRS - Fiche Toxicologique (toxicological sheet) 12. Patty - Industrial Hygiene and Toxicology 13. N.I. Sax - Dangerous properties Industrial Materials-7, 1989 Edition 14. ECHA website Note for users: The information contained in present sheet are based on our own knowledge on date last version. Users must verify suitability and thoroughness provided information according to each specific use product. This document must be regarded as a guarantee on any specific product property. The use this product is subject to our direct control; refore, users must, under ir own responsibility, comply with current health and safety laws and regulations. The producer is relieved from any liability arising from improper uses. Provide appointed staff with adequate training on how to use chemical products. Changes to previous review: The following sections were modified: 02 / 04 / 06 / 07 / 08 / 11 / 12 / 15 / 16.