Advanced Neuromonitoring Solutions ICP. Oxygen Partial Pressure, Intracranial Pressure and Temperature Measurement. Drainage

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Ira Daniels
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1 Advanced Neuromonitoring Solutions Oxygen Partial Pressure, Intracranial Pressure and Temperature Measurement Drainage O Temperature

Table of contents Page Microchip catheters with maximum precision NEUROVENT Microchip catheters 3 NEUROVENT microchip catheters are used for the reliable measurement of: and temperature measurement

oxygen partial pressure measurement 10-11 is measured using semiconductor pressure sensors. The quenching process of fluorescence is used to measure p ti O 2.

2 Table of contents Page Microchip catheters with maximum precision NEUROVENT Microchip catheters 3 NEUROVENT microchip catheters are used for the reliable measurement of: and temperature measurement 4-5 Accessories for and temperature measurement 6-7 Oxygen partial pressure measurement 8-9 (intracranial pressure) ICT (intracranial temperature) p ti O 2 (oxygen partial pressure) Accessories for oxygen partial pressure measurement is measured using semiconductor pressure sensors. The quenching process of fluorescence is used to measure p ti O 2. Consequently the level and changes in the parameters are measured safely, quickly and accurately. RAUMEDIC offers a wide range of microchip catheters for parenchyma as well as ventricular measurement. NEUROVENT -PTO: Pressure (), Temperature, Oxygen Partial Pressure (p ti O 2 ) References: An outcome analysis of two different procedures of burr-hole trephine and external ventricular drainage in acute hydrocephalus. Schödel P, Proescholdt M, Ullrich OW, Brawanski A, Schebesch KM J Clin Neurosci Feb;19(2): Bench test assessment of the new Raumedic Neurvent-P sensor: a technical report by the BrainIT Group. Citerio G, Piper I, Cormio M, Galli D, Cazzaniga S, Enblad P, Nilsson P, Contant C, Chambers I; BrainIT Group. Acta Neurochir (Wien) Nov;146(11): Accuracy and stability of temperature probes for intracranial applications. Alessandri B, Hoelper BM, Behr R, Kempski O. J Neurosci Methods Oct 30;139(2): Clinical evaluation of a new intracranial pressure monitoring device. Stendel R, Heidenreich J, Schilling A, Akhavan-Sigari R, Kurth R, Picht T, Pietilä T, Suess O, Kern C, Meisel J, Brock M. Acta Neurochir (Wien) Mar;145(3):185-93; discussion 193. Evaluation of a novel brain tissue oxygenation probe in an experimental swine model. Orakcioglu B, Sakowitz OW, Neumann JO, Kentar MM, Unterberg A, Kiening KL. Neurosurgery Dec;67(6): ; discussion Brain tissue oxygen monitoring: a study of the in vitro accuracy and stability of the Neurovent-PTO and Licox sensors. Purins K, Enblad P, Sandhagen B, Lewén A. Acta Neurochir (Wien) Apr;152(4):

Temperature Intracranial pressure and temperature measurement NEUROVENT -P and NEUROVENT Drainage Intracranial pressure () and temperature measurement can be achieved safely,

Parenchyma monitoring of with NEUROVENT-P; with integrated temperature measurement using NEUROVENT-P-TEMP Ventricular monitoring of and CSF drainage with NEUROVENT; with

NEUROVENT-P 092946-002 NEUROVENT-P-TEMP + temperature 094268-002 Parenchyma Ventricular NEUROVENT + drainage, stylet 092956-002 NEUROVENT-IFD-S + drainage, inset guide wire

temperature, inset guide wire soft 094288-002 NEUROVENT-TEMP-IFD-R + drainage + temperature, inset guide wire rigid 095327-002 NEUROVENT-Sleeve Housing in parenchyma +

3 Pa) Bandwidth > 100 Hz Measurement range temperature sensor +25 C to +45 C +77 F to +113 F Temperature accuracy in measurement range ±0.

6 F) Less than 2 mmhg during the first week at 37 C (98.6 F) Average deviation 0.

measurement NEUROVENTSleeve Housing Connection directly to the patient monitor Compatible with all standard patient monitors Pressure measurement during transport Consistent

3 Temperature Intracranial pressure and temperature measurement NEUROVENT -P and NEUROVENT Drainage Intracranial pressure () and temperature measurement can be achieved safely, quickly and accurately using RAUMEDIC s innovative catheters with semiconducter sensors. Parenchyma monitoring of with NEUROVENT-P; with integrated temperature measurement using NEUROVENT-P-TEMP Ventricular monitoring of and CSF drainage with NEUROVENT; with integrated temperature measurement using NEUROVENT-TEMP Parenchyma monitoring of and ventricular drainage using NEUROVENT-Sleeve Housing Technical Data Catheters Diameter NEUROVENT-P NEUROVENT-P-TEMP + temperature Parenchyma Ventricular NEUROVENT + drainage, stylet NEUROVENT-IFD-S + drainage, inset guide wire soft NEUROVENT-IFD-R + drainage, inset guide wire rigid NEUROVENT-TEMP + drainage + temperature, stylet NEUROVENT-TEMP-IFD-S + drainage + temperature, inset guide wire soft NEUROVENT-TEMP-IFD-R + drainage + temperature, inset guide wire rigid NEUROVENT-Sleeve Housing in parenchyma + ventricular drainage Pressure measurement range -50 to mmhg (-6.7 to 33.3 Pa) Bandwidth > 100 Hz Measurement range temperature sensor +25 C to +45 C +77 F to +113 F Temperature accuracy in measurement range ±0.1 C Catheter material Polyurethane Pressure sensibility 5 µv/v/mmhg NEUROVENT-P NEUROVENT Zero Drift Pressure Less than 1 mmhg during the first 24 hours at 37 C (98.6 F) Less than 2 mmhg during the first week at 37 C (98.6 F) Average deviation 0.6 mmhg after 5 days* Clinical benefits: No additional monitor Plug & Play system no catheter calibration required Simultaneous measurement, CSF drainage and temperature measurement NEUROVENTSleeve Housing Connection directly to the patient monitor Compatible with all standard patient monitors Pressure measurement during transport Consistent reproducibility of pressure curves with high precision resolution for wave analysis Excellent stability and linearity of measuring values Zero Point Simulator allows for easy replacement of patient monitor without losing measured values 4 * Bench test assessment of the new Raumedic Neurovent-P sensor: a technical report by the BrainIT group Citerio G., Piper I., Cormio M., Galli D., Cazzaniga S., Enblad P., Nilsson P., Contant C., and Chambers I., BrainIT Group Acta Neurochirurgica (Wien). 2004, Aug; DOI: /s z 5

Allen key 1 Measuring chain from the catheter to

KIT CH5 (parenchyma) 091868-002 DRILL KIT CH5

(parenchyma) 090506-002 Tunneling Sleeve CH12

sealing function NPS2 Available for all standard

094328-001 -TEMP-Adapter 094323-001 -TEMP-Adapter

NPS2 GE/MARQUETTE 093807-001 NPS2 Siemens/Dräger

091676-001 NPS2 Datex Ohmeda 090924-001 NPS2

4 Components of the RAUMEDIC BOLT KIT 1. BOLT including seal and fixing cap 2. Dura opener 3. Screwing in tool BOLT and DRILL KIT Components of the RAUMEDIC DRILL KIT 4. DRILL bit with stopper 5. Allen key 1 Measuring chain from the catheter to the patient monitor Implantation Accessories BOLT KIT CH5 (parenchyma) DRILL KIT CH5 (parenchyma) BOLT KIT CH9 (ventricular) DRILL KIT CH9 (ventricular) Tunneling Sleeve CH8 (parenchyma) Tunneling Sleeve CH12 (ventricular) BOLT KIT Advantages: Low profile -TEMP-Cable Art.No.: Self-cutting conical thread with sealing function NPS2 Available for all standard monitor types Cables and Adapters -TEMP-Cable TEMP-Adapter TEMP-Adapter Philips/HP NPS2 Philips/HP NPS2 GE/MARQUETTE NPS2 Siemens/Dräger Infinity NPS2 Nihon Kohden BSM NPS2 Datex Ohmeda NPS2 SpaceLabs NPS2 Fukuda Denshi NPS2 Schiller NPS2 Hellige Patient monitor Alternative NPS3 NPS2 for additional monitor types upon request Mobile Pressure Measurement NPS

Oxygen partial pressure measurement NEUROVENT -PTO Measurement of oxygen partial pressure (ptio2) shows the available oxygen in the brain tissue and allows for early

Catheters Dimension NEUROVENT-PTO + temperature + ptio2 NEUROVENT-PTO 2L + temperature + ptio2 for use with BOLT KIT PTO 2L 095108-002 NEUROVENT-TO Temperature + ptio2 3F

and temperature measurements in the parenchy- NEUROVENT-PTO ma.

temperature measurements in the parenchyma Pressure measurement range -50 to + 250 mmhg (-6.7 to 33.

1 C Catheter material Polyurethane Pressure sensibility 5 µv/v/mmhg Measurement process ptio2 Fiber optic ptio2 measuring surface 22 mm2 Measurement* range ptio2 0-150

hours at 37 C (98.6 F) Less than 2 mmhg during the first week at 37 C (98.6 F) Average deviation 0.

oxygen consumption by the O2 sensor Large oxygen sensor window NEUROVENT-PTO 2L No refrigeration of catheter required Application with BOLT KIT PTO 2L and Tunneling Sleeve.

5 Oxygen partial pressure measurement NEUROVENT -PTO Measurement of oxygen partial pressure (ptio2) shows the available oxygen in the brain tissue and allows for early detection of cerebral damage to help prevent secondary injury. The quenching process of fluorescence is used to measure ptio2. Catheters Dimension NEUROVENT-PTO + temperature + ptio2 NEUROVENT-PTO 2L + temperature + ptio2 for use with BOLT KIT PTO 2L NEUROVENT-TO Temperature + ptio2 3F NEUROVENT-PTO; provides oxygen partial pressure, and temperature measurements in the parenchyma NEUROVENT-PTO 2L; provides oxygen partial pressure, and temperature measurements in the parenchy- NEUROVENT-PTO ma. Catheter designed specifically for BOLT KIT PTO 2L (two lumen BOLT); to be used with microdialysis Technical Data NEUROVENT-TO; provides oxygen partial pressure and temperature measurements in the parenchyma Pressure measurement range -50 to mmhg (-6.7 to 33.3 kpa) Bandwidth > 100 Hz Measurement range temperature sensor +25 C to +45 C +77 F to F Temperature accuracy in measurement range ± 0.1 C Catheter material Polyurethane Pressure sensibility 5 µv/v/mmhg Measurement process ptio2 Fiber optic ptio2 measuring surface 22 mm2 Measurement* range ptio mmhg One catheter; three measurement functions ICT ptio2 NEUROVENT-TO Catheter for measuring temperature and ptio2 Zero Drift Pressure Less than 1 mmhg during the first 24 hours at 37 C (98.6 F) Less than 2 mmhg during the first week at 37 C (98.6 F) Average deviation 0.6 mmhg after 5 days** Clinical advantages: Parenchyma pressure, temperature and ptio2 measurement in one catheter Plug & play system no catheter calibration required No oxygen consumption by the O2 sensor Large oxygen sensor window NEUROVENT-PTO 2L No refrigeration of catheter required Application with BOLT KIT PTO 2L and Tunneling Sleeve. Data acquisition using RAUMEDIC EASY logo Excellent long-term stability and linearity of measuring values Compatible with standard patient monitors 8 *Measurement accuracy ± 2.5 mmhg ptio2 (for < 120 mmhg ptio2) **Bench test assessment of the new Raumedic Neurovent-P sensor: a technical report by the BrainIT group Citerio G., Piper I., Cormio M., Galli D., Cazzaniga S., Enblad P., Nilsson P., Contant C., and Chambers I., BrainIT Group Acta Neurochirurgica (Wien). 2004, Aug; DOI: /s z 9

Implantation Accessories BOLT KIT PTO 2L BOLT KIT PTO BOLT with single lumen, only for NEUROVENT-PTO/-TO CH5 Dimension 096026-001 DRILL KIT

bit and allen key CH9 091668-002 Spliceable Tunneling Sleeve Parenchyma Tunneling Sleeve for NEUROVENT-PTO 2L CH8 090506-002 BOLT with two

Ohmeda 094888-001 Cable DATALOGGER Hellige 094898-001 Cable DATALOGGER SpaceLabs 094967-002 Cable DATALOGGER Nihon Kohden 096006-001

6 Implantation Accessories BOLT KIT PTO 2L BOLT KIT PTO BOLT with single lumen, only for NEUROVENT-PTO/-TO CH5 Dimension DRILL KIT CH5 Drill bit and allen key CH BOLT KIT PTO 2L BOLT with two lumens, only for NEUROVENT-PTO 2L CH DRILL KIT CH9 Drill bit and allen key CH Spliceable Tunneling Sleeve Parenchyma Tunneling Sleeve for NEUROVENT-PTO 2L CH BOLT with two lumens for safe and functional implantation of the NEUROVENT-PTO 2L and a microdialysis catheter Data Acquisition and Accessories EASY logo Acquisition of + ICT + ptio2 measurement values Cable LWL Fiber optic connecting cable for ptio2 to EASY logo Connecting cable for pressure and temperature to EASY logo Stand Holder Pole mounting device for EASY logo Table Stand Table mounting device for EASY logo Cable PTO EASY logo Connecting Cables (EASY logo to patient monitor) 10 Cable DATALOGGER GE/MARQUETTE Cable DATALOGGER Philips/HP Cable DATALOGGER Siemens/Dräger Infinitiv Cable DATALOGGER Datex Ohmeda Cable DATALOGGER Hellige Cable DATALOGGER SpaceLabs Cable DATALOGGER Nihon Kohden Acquisition of, ICT and ptio2 measurement values using a single device Simple and safe operating interface Light weight Analog output Compatible with standard patient monitors 11

com/neuro 800-961-2122 106 Commerce Street, Suite 108 Lake Mary, FL 32746 C96N009 US 02_2014 Copyright by

7 Service Worldwide! RAUMEDIC Brain Competence RAUMEDIC, INC Edwards Ferry Road Leesburg, Virginia 20176, USA Commerce Street, Suite 108 Lake Mary, FL C96N009 US 02_2014 Copyright by RAUMEDIC AG Sources: Heading: AlienCat Fotolia.com rear page: Sebastian Kaulitzki Fotolia.com Toll Free: Tel: Fax:

Advanced Neuromonitoring Solutions ICP. Oxygen Partial Pressure, Intracranial Pressure and. Temperature. Drainage. Measurement O 2.

Advanced Neuromonitoring Solutions ICP Oxygen Partial Pressure, Intracranial Pressure and Temperature Measurement Drainage Temperature Table of contents Page Microchip catheters with maximum precision